Research projects

Professor Kevin Harrington, Magnetic Resonance Group

Current research projects/themes include

• Evaluation and qualification of MRI biomarkers of diffuse adult and paediatric glioma, and neuroblastoma.
• The role of platelet-derived growth factor, and effects of putative platelet-derived growth factor (PDGF) antagonists, on tumour vascular morphology and function.
• Identification of in vivo biomarkers of tumour response to hypoxia-inducible factor-1 (HIF-1) inhibition.
• Evaluation and qualification of susceptibility magnetic resonance imaging (MRI)-derived biomarkers of tumours with velocity CT imaging of vascular corrosion casts.
• Imaging biomarkers in malignant bone disease.
• Non-invasive imaging of tumour elasticity using magnetic resonance (MR) elastography.
• The use of intrinsic susceptibility blood oxygen level-dependent (BOLD) MRI to assess tumour hypoxia.