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Division of Genetics and Epidemiology

The Division of Genetics and Epidemiology is internationally renowned for its pioneering work in understanding the underlying genetic causes of cancer risk. High-quality laboratory, epidemiological and clinical research within the division is driven by energetic, innovative leadership and complemented by participation in national and international research consortiums, clinical collaborations and technological partnerships.

Current vacancies

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The research leaders in the division – formed between the division and the Cancer Genetics Unit at The Royal Marsden NHS Foundation Trust – provide exceptional opportunities to translate scientific discoveries for clinical benefit, particularly in the development of new ways of detecting people at increased risk of cancer and strategies to help them manage that risk.

Gene discovery research in the Division has been extremely successful, identifying genetic predisposition factors in a wide variety of cancers, including breast, ovarian, prostate, lung, testicular, brain, haematological and childhood cancers. The work has revealed important insights into the genetic architecture of cancer, and has identified both genetic and epigenetic factors that play an important role in determining cancer risk.

Researchers are also conducting several long-term epidemiological studies looking at how genetic, behavioural and environmental factors may affect cancer risk. The division hosts the Breakthrough Generations Study – funded by Breakthrough Breast Cancer – which is one of the world’s largest studies of the causes of breast cancer, involving more than 100,000 women across the UK.

Head of Division

Professor Richard Houlston

Professor Richard Houlston

Head of Division

Professor Richard Houlston is Head of the Division of Genetics and Epidemiology. His research focuses on the identification and characterisation of genetic susceptibility to cancer.

+44 20 8722 4175 ORCID 0000-0002-5268-0242

Research groups

Cancer Genomics

Group leader: Professor Richard Houlston

Professor Richard Houlston’s Cancer Genomics Team works to identify cancer susceptibility genes and understand how these can cause cancer.

Clinical Cancer Epidemiology

Group leader: Professor Amy Berrington

Professor Amy Berrington’s group is investigating the late-effects of cancer treatments, medical radiation exposures and other medications to improve outcomes for patients.

Integrative Cancer Epidemiology

Group leader: Professor Montse Garcia-Closas

Professor Montserrat Garcia-Closas's Group investigates the causes of cancer with the aim of understanding carcinogenic processes and improving risk assessment for precision prevention.

Myeloma Group

Group leader: Professor Richard Houlston

The Myeloma Group led by Professor Richard Houlston is investigating new personalised treatments for the blood cancer myeloma.

Myeloma Molecular Therapy

Group leader: Dr Martin Kaiser

Dr Martin Kaiser’s Team aims to design gentler, tailored therapies for patients with multiple myeloma, an immune cell cancer of the bone marrow.


Group leader: Professor Rosalind Eeles

Professor Rosalind Eeles’ Oncogenetics Group aims to translate laboratory findings about genetic risk factors for cancer, particularly prostate cancer, into the clinic.

Translational Genetics

Group leader: Professor Clare Turnbull

Professor Clare Turnbull's group is investigating ways to optimise ‘next-generation’ sequencing technologies and analyses of these data in order to identify novel cancer predisposition genes.