Working life and benefits

Department/Directorate Information: Division of Clinical Studies - Clinical Trials and Statistics Unit (ICR-CTSU) The ICR-CTSU is a Cancer Research UK-funded, internationally recognised methodologist led clinical trials unit, providing cancer-focused clinical trial research expertise. We lead pioneering, efficient, high-quality, and impactful trials across the phases. Our expertise ranges from experimental medicine early phase studies exploring biological efficacy to trials which may deliver widespread change to routine practice, underpinned by applied methodology to drive forward clinical trial innovation. See our clinical trials Role Summary The Group Leader will lead a component of ICR-CTSU’s portfolio of clinical trials research. The post holder will join an existing faculty and seek to further develop and grow the portfolio in line with ICR-CTSU’s overall strategy; taking responsibility for a number of ongoing trials as well as the development of new trials. There will be the opportunity to develop and grow a team including the potential for a Postdoctoral Training Fellow and/ or a Trial Manager. We seek an experienced statistician / biostatistician with a strong research interest in clinical trials methodology and a passion for direct involvement in the oversight and leadership of academic clinical trials. The successful candidate will work closely with the Director of ICR-CTSU to further enhance the Unit’s internationally recognised strength in clinical trial design, conduct and analysis. The post holder will be expected to make a substantial independent intellectual contribution to clinical trials projects and be proactive in leading and contributing to broad initiatives that enhance the overall effectiveness of ICR-CTSU. The appointee will contribute to the overall scientific life of the ICR including the newly established ICR/Royal Marsden Hospital’s Centre for Trials and Population Data Science, by providing mentorship to more junior colleagues and acting as an academic leader. We seek an individual who will work closely and collaboratively with other faculty/Group Leaders at the ICR and with international/national key opinion leaders to extend the breadth and depth of ICR-CTSU’s biologically rich clinical trials portfolio. In partnership with clinical opinion leaders, this individual will generate research funds to conduct and deliver clinical trials research at the international forefront. Presentation at national and international conferences, production of top-quality research outputs and substantial professional contribution to wider clinical trial network bodies are expected. Enthusiasm for team-based science in a collaborative interdisciplinary environment is essential. The appointment will be based on track record and the ability and willingness to engage in team science. The successful appointee will have access to ICR’s successful PhD training programme and core facilities. Key Requirements Higher degree (MSc or PhD) in medical statistics/biostatistics or an allied field (e.g. public health, epidemiology, data science) with relevant work experience Significant experience as a clinical trials, medical statistician or bio-statistician within the academic or commercial sector; a blend of both would be highly desirable A desire to apply existing and novel statistical methods to the requirements of a diverse range of statistical problems A broad understanding of cancer research Ability to lead a Clinical Trials Unit based research group As part of your online application, you will be required to upload your full CV which will pre-populate your application form, you will also be asked to attach the following documents and failure to do so will mean your application cannot be considered on this occasion: Lists of major publications, achievements, research grants and distinctions. A PDF of a maximum of five key publications, or other research outputs (e.g. patents) that best demonstrate previous productivity or a single document giving hyperlinks to these outputs. You must also complete the personal statement section of the application form in the format of a cover letter including the names and contact details of three academic referees Joining as a Group Leader, you will be given outstanding support to help you to continue to develop in your career. Along with a start-up package of funding, you will also have access to resources to establish your group, including support for recruiting key group members, such as PhD students and postdoctoral researchers. We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Professor Emma Hall ([email protected])

Applications are invited for the post of Clinical Research Fellow in the Prostate Cancer Targeted Therapy Group (PCTTG) at The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust to contribute to the discovery, development and delivery of the next generation of treatments, technologies and methodology into clinical care. This post is an excellent opportunity to be centrally involved in the management of patients with advanced prostate cancer enrolled in clinical trials of experimental anti-cancer drugs. In addition, the applicant will be encouraged to become involved in translational research that could lead to a PhD and will gain experience in translational and clinical research including the conduct of clinical trials and manuscript writing. To be considered applicants must meet the following essential criteria: Full registration with the General Medical Council, Acquisition of MRCP, and Clinical experience in managing cancer patients. Department/Directorate Information The PCTTG, under the leadership and guidance of Professor Johann de Bono and Dr Adam Sharp, has led on the development of many of the new drugs currently used for the management of advanced prostate cancer including abiraterone, cabazitaxel, enzalutamide, olaparib and Lutetium PSMA. The Unit is based at the Royal Marsden in the Oak Cancer Centre, a day-care area with outpatient facilities exclusively dedicated to the care and treatment of patients enrolled in clinical trials and is closely linked to our translational research laboratories at The Institute of Cancer Research. What we offer A dynamic and supportive research environment Access to state-of-the-art facilities and professional development opportunities Collaboration with leading researchers in the field Competitive salary and pension We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Professor Johann de Bono via email on [email protected]

We currently have an exciting opportunity for a self-motivated and experienced HR Adviser to join our HR Operations team for 12 months. Providing dedicated partnering with client departments, you’ll work closely with line managers to provide proactive and pragmatic advice and guidance on all aspects of people management, taking ownership of a busy employee relations caseload. You will also be responsible for supervising the work of our HR Administrative Team to ensure our monthly payroll input is submitted accurately and on time. You will work closely with other HR teams, including Recruitment, Systems and Information, and Learning and Organisational Development to ensure the provision of an effective, end to end HR service to Scientific and Professional Services teams across the ICR. Key Requirements You will have previous HR advisory experience, as well as a sound experience of managing employee relations cases end-to-end. You’ll need to be highly computer-literate, and have excellent attention to detail, with strong organisational and prioritisation skills to deliver effectively within a fast-paced environment. You will also have first-rate customer service skills to build and maintain collaborative relationships with colleagues across the organisation. Previous line management experience, and of managing small scale team restructures, including knowledge and understanding of TUPE processes would be a distinct advantage. Human Resources Directorate We know that talented, brilliant, passionate people lie at the heart of the ICR. That’s why we provide the policies, procedures, systems and people management infrastructure to recruit, retain, motivate and develop our people to achieve their full potential. We offer both operational and strategic support to teams across the ICR. We are organised across four main functions: HR Operations Learning and Organisational Development Pensions Reward, Information and Systems The ICR’s future success depends on recruiting the very best people with the very best skills and our HR strategy ensures that we have the organisational capacity and capability to deliver this. We encourage all applicants to access the job description pack attached for more detailed information regarding this role. For an informal discussion regarding the Sutton based role, please contact Karen Grieff via email on [email protected].

Under the guidance of XNAT Team lead Simon Doran, we are seeking to recruit a Data Manager for the joint Institute of Cancer Research and Royal Marsden XNAT Repository, which holds deidentified imaging and associated clinical data underpinning a huge variety of cancer research projects. The successful candidate will join a dynamic team, with rigorous standards and a large portfolio of state-of-the-art projects and clinical studies. They will play a key role in information governance, information security and data management; liaison with XNAT users and external site teams; training of XNAT users; public and patient involvement and engagement; and active collaboration with scientific teams to contribute to ongoing and future research projects. About you The successful candidate must have: an undergraduate degree (or higher) in computer science, physical sciences, mathematics, computational biology, medicine or a related field; knowledge of computing in a medical field; attention to detail and the ability to use computer software accurately, to maintain adherence to procedures and clinical/regulatory standards; the ability to forge trusted working relationships with peers, senior colleagues and "research customers"; and the ability to respond quickly to issues, taking ownership while ensuring that others engage effectively, acting as a good team player but with the ability to work independently. Ideally, you will also have: experience of engaging in scientific projects with the ability to understand and discuss them with researchers; experience of previous projects involving imaging data; previous exposure to the XNAT imaging platform; and demonstrated programming skills in one or more high-level programming languages (e.g., Python, Java, C++ and JavaScript) and Linux shell scripts. Department/Directorate Information The ICR's Division of Radiotherapy and Imaging (https://www.icr.ac.uk/research-and-discoveries/icr-divisions/radiotherapy-and-imaging) investigates new imaging methods to diagnose cancer, and ways in which advances in technology and molecular biology can improve radiation treatment. It uses imaging to evaluate the response to treatment in vivo, through techniques measuring aspects of tumour biology. Your colleagues in the MRI team will include world-leading clinical radiologists and specialists in imaging informatics, artificial intelligence, MRI physics and image analysis. We operate a state-of-the-art image repository based on the XNAT platform, working at the interface between the Institute and the Royal Marsden. This holds the curated reference copy of deidentified imaging and associated clinical data for more than 250 separate academic activities. What we offer A dynamic and supportive research environment Access to state-of-the-art facilities and professional development opportunities Collaboration with leading researchers in the field Excellent opportunities to gain experience Competitive salary and pension We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact [email protected].