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Let’s finish it: 
help us revolutionise cancer treatment

We aim to discover a new generation of treatments that will turn cancer into a manageable or curable disease.

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 “Palbociclib allows me to live a good life with cancer – and I want all cancer patients to have this hope and optimism for the future.” Hear Christine’s story.

Following her initial breast cancer diagnosis and successful treatment in 2012, Christine was shocked to discover that her cancer had spread to her brain in 2018. Thanks to palbociclib – a targeted drug that works by blocking proteins that help cancer cells divide and spread – Christine is now living well with cancer, including a new-found passion for cycling. 

Taking on the challenge of drug resistance

Our scientists have led the discovery and development of many targeted treatments that are helping more cancer patients like Christine, live longer and with fewer side-effects. But we now know that some cancers adapt to their environments within our bodies to side-step those drugs designed to halt their progress. 

We are now poised to take on this challenge with the world’s first anti-evolution 'Darwinian' drug discovery programme, in which we will focus on understanding, anticipating and overcoming cancer evolution, and preventing drug resistance.

To deliver this pioneering drug discovery programme, we are constructing a major new research building – the Centre for Cancer Drug Discovery – to bring over 300 scientists together in one collaborative space. Our Centre will pave the way for a new era of drug discovery so that patients do not have to give up on their dreams for the future. Our aim is to help them defeat their cancer and finish all the things they started.

How you can help

With your help we can discover treatments so smart and targeted that even advanced cancer can be managed long-term and effectively cured. Please donate today – and let’s finish cancer together. 

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