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Journal Articles

Zormpas-Petridis, K., Failmezger, H., Roxanis, I., Blackledge, M.D., Jamin, Y. & Yuan, Y. (2018). Capturing global spatial context for accurate cell classification in skin cancer histology. Corr, Vol.abs/1808.02355.

Tucker, E.R., Tall, J.R., Danielson, L.S., Gowan, S., Jamin, Y., Robinson, S.P., Banerji, U. & Chesler, L. (2017). Immunoassays for the quantification of ALK and phosphorylated ALK support the evaluation of on-target ALK inhibitors in neuroblastoma. Molecular oncology, Vol.11 (8), pp. 996-1006.

Almeida, G.S., Panek, R., Hallsworth, A., Webber, H., Papaevangelou, E., Boult, J.K., Jamin, Y., Chesler, L. & Robinson, S.P. (2017). Pre-clinical imaging of transgenic mouse models of neuroblastoma using a dedicated 3-element solenoid coil on a clinical 3T platform. British journal of cancer, Vol.117 (6), pp. 791-800.

Guan, J., Tucker, E.R., Wan, H., Chand, D., Danielson, L.S., Ruuth, K., El Wakil, A., Witek, B., Jamin, Y., Umapathy, G., et al. (2016). The ALK inhibitor PF-06463922 is effective as a single agent in neuroblastoma driven by expression of ALK and MYCN. Disease models & mechanisms, Vol.9 (9), pp. 941-952.

Hill, D.K., Kim, E., Teruel, J.R., Jamin, Y., Widerøe, M., Søgaard, C.D., Størkersen, Ø., Rodrigues, D.N., Heindl, A., Yuan, Y., et al. (2016). Diffusion-weighted MRI for early detection and characterization of prostate cancer in the transgenic adenocarcinoma of the mouse prostate model. Journal of magnetic resonance imaging, Vol.43 (5), pp. 1207-1217.

Vaughan, L., Clarke, P.A., Barker, K., Chanthery, Y., Gustafson, C.W., Tucker, E., Renshaw, J., Raynaud, F., Li, X., Burke, R., et al. (2016). Inhibition of mTOR-kinase destabilizes MYCN and is a potential therapy for MYCN-dependent tumors. Oncotarget, Vol.7 (36).

Osborne, J.D., Matthews, T.P., McHardy, T., Proisy, N., Cheung, K.-., Lainchbury, M., Brown, N., Walton, M.I., Eve, P.D., Boxall, K.J., et al. (2016). Multiparameter Lead Optimization to Give an Oral Checkpoint Kinase 1 (CHK1) Inhibitor Clinical Candidate: (R)-5-((4-((Morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CCT245737). J med chem, Vol.59 (11), pp. 5221-5237.  show abstract

Yogev, O., Barker, K., Sikka, A., Almeida, G.S., Hallsworth, A., Smith, L.M., Jamin, Y., Ruddle, R., Koers, A., Webber, H.T., et al. (2016). p53 Loss in MYC-Driven Neuroblastoma Leads to Metabolic Adaptations Supporting Radioresistance. Cancer research, Vol.76 (10), pp. 3025-3035.

Jamin, Y., Boult, J.K., Li, J., Popov, S., Garteiser, P., Ulloa, J.L., Cummings, C., Box, G., Eccles, S.A., Jones, C., et al. (2015). Exploring the biomechanical properties of brain malignancies and their pathologic determinants in vivo with magnetic resonance elastography. Cancer res, Vol.75 (7), pp. 1216-1224.  show abstract

Papaevangelou, E., Almeida, G.S., Jamin, Y., Robinson, S.P. & deSouza, N.M. (2015). Diffusion-weighted MRI for imaging cell death after cytotoxic or apoptosis-inducing therapy. British journal of cancer, Vol.112 (9), pp. 1471-1479.

Dolman, M.E., Poon, E., Ebus, M.E., den Hartog, I.J., van Noesel, C.J., Jamin, Y., Hallsworth, A., Robinson, S.P., Petrie, K., Sparidans, R.W., et al. (2015). Cyclin-Dependent Kinase Inhibitor AT7519 as a Potential Drug for MYCN-Dependent Neuroblastoma. Clinical cancer research, Vol.21 (22), pp. 5100-5109.

O’Connor, J.P., Boult, J.K., Jamin, Y., Babur, M., Finegan, K.G., Williams, K.J., Little, R.A., Jackson, A., Parker, G.J., Reynolds, A.R., et al. (2015). Oxygen enhanced MRI accurately identifies, quantifies, and maps hypoxia in preclinical cancer models. Cancer research, (in press).

Li, J., Jamin, Y., Boult, J.K., Cummings, C., Waterton, J.C., Ulloa, J., Sinkus, R., Bamber, J.C. & Robinson, S.P. (2014). Tumour biomechanical response to the vascular disrupting agent ZD6126 in vivo assessed by magnetic resonance elastography. Br j cancer, Vol.110 (7), pp. 1727-1732.  show abstract

Jamin, Y., Eykyn, T.R., Poon, E., Springer, C.J. & Robinson, S.P. (2014). Detection of the prodrug-activating enzyme carboxypeptidase G2 activity with chemical exchange saturation transfer magnetic resonance. Mol imaging biol, Vol.16 (2), pp. 152-157.  show abstract

Jamin, Y., Glass, L., Hallsworth, A., George, R., Koh, D.-., Pearson, A.D., Chesler, L. & Robinson, S.P. (2014). Intrinsic susceptibility MRI identifies tumors with ALKF1174L mutation in genetically-engineered murine models of high-risk neuroblastoma. Plos one, Vol.9 (3), p. e92886.  show abstract

Baker, L.C., Boult, J.K., Jamin, Y., Gilmour, L.D., Walker-Samuel, S., Burrell, J.S., Ashcroft, M., Howe, F.A., Griffiths, J.R., Raleigh, J.A., et al. (2013). Evaluation and immunohistochemical qualification of carbogen-induced ΔR₂ as a noninvasive imaging biomarker of improved tumor oxygenation. Int j radiat oncol biol phys, Vol.87 (1), pp. 160-167.  show abstract

Jamin, Y., Tucker, E.R., Poon, E., Popov, S., Vaughan, L., Boult, J.K., Webber, H., Hallsworth, A., Baker, L.C., Jones, C., et al. (2013). Evaluation of clinically translatable MR imaging biomarkers of therapeutic response in the TH-MYCN transgenic mouse model of neuroblastoma. Radiology, Vol.266 (1), pp. 130-140.  show abstract

Hill, D.K., Orton, M.R., Mariotti, E., Boult, J.K., Panek, R., Jafar, M., Parkes, H.G., Jamin, Y., Miniotis, M.F., Al-Saffar, N.M., et al. (2013). Model Free Approach to Kinetic Analysis of Real-Time Hyperpolarized C-13 Magnetic Resonance Spectroscopy Data. Plos one, Vol.8 (9).

Burrell, J.S., Walker-Samuel, S., Baker, L.C., Boult, J.K., Jamin, Y., Halliday, J., Waterton, J.C. & Robinson, S.P. (2013). Exploring ΔR(2) * and ΔR(1) as imaging biomarkers of tumor oxygenation. J magn reson imaging, Vol.38 (2), pp. 429-434.  show abstract

Brockmann, M., Poon, E., Berry, T., Carstensen, A., Deubzer, H.E., Rycak, L., Jamin, Y., Thway, K., Robinson, S.P., Roels, F., et al. (2013). Small molecule inhibitors of aurora-a induce proteasomal degradation of N-myc in childhood neuroblastoma. Cancer cell, Vol.24 (1), pp. 75-89.  show abstract

Hill, D.K., Jamin, Y., Orton, M.R., Tardif, N., Parkes, H.G., Robinson, S.P., Leach, M.O., Chung, Y.-. & Eykyn, T.R. (2013). ¹H NMR and hyperpolarized ¹³C NMR assays of pyruvate-lactate: a comparative study. Nmr biomed, Vol.26 (10), pp. 1321-1325.  show abstract

Beloueche-Babari, M., Jamin, Y., Arunan, V., Walker-Samuel, S., Revill, M., Smith, P.D., Halliday, J., Waterton, J.C., Barjat, H., Workman, P., et al. (2013). Acute tumour response to the MEK1/2 inhibitor selumetinib (AZD6244, ARRY-142886) evaluated by non-invasive diffusion-weighted MRI. Br j cancer, Vol.109 (6), pp. 1562-1569.  show abstract

Hill, D.K., Orton, M.R., Mariotti, E., Boult, J.K., Panek, R., Jafar, M., Parkes, H.G., Jamin, Y., Miniotis, M.F., Al-Saffar, N.M., et al. (2013). Model free approach to kinetic analysis of real-time hyperpolarized 13C magnetic resonance spectroscopy data. Plos one, Vol.8 (9), p. e71996.  show abstract

Boult, J.K., Jamin, Y., Jacobs, V., Gilmour, L.D., Walker-Samuel, S., Halliday, J., Elvin, P., Ryan, A.J., Waterton, J.C. & Robinson, S.P., et al. (2012). False-negative MRI biomarkers of tumour response to targeted cancer therapeutics. Br j cancer, Vol.106 (12), pp. 1960-1966.  show abstract

Baker, L.C., Boult, J.K., Walker-Samuel, S., Chung, Y.-., Jamin, Y., Ashcroft, M. & Robinson, S.P. (2012). The HIF-pathway inhibitor NSC-134754 induces metabolic changes and anti-tumour activity while maintaining vascular function. Br j cancer, Vol.106 (10), pp. 1638-1647.  show abstract

Berry, T., Luther, W., Bhatnagar, N., Jamin, Y., Poon, E., Sanda, T., Pei, D., Sharma, B., Vetharoy, W.R., Hallsworth, A., et al. (2012). The ALK(F1174L) Mutation Potentiates the Oncogenic Activity of MYCN in Neuroblastoma. Cancer cell, Vol.22 (1), pp. 117-130.

Burrell, J.S., Bradley, R.S., Walker-Samuel, S., Jamin, Y., Baker, L.C., Boult, J.K., Withers, P.J., Halliday, J., Waterton, J.C. & Robinson, S.P., et al. (2012). MRI measurements of vessel calibre in tumour xenografts: comparison with vascular corrosion casting. Microvasc res, Vol.84 (3), pp. 323-329.  show abstract

Bielen, A., Box, G., Perryman, L., Bjerke, L., Popov, S., Jamin, Y., Jury, A., Valenti, M., Brandon, A.D., Martins, V., et al. (2012). Dependence of Wilms tumor cells on signaling through insulin-like growth factor 1 in an orthotopic xenograft model targetable by specific receptor inhibition. Proc natl acad sci u s a, Vol.109 (20), pp. E1267-E1276.  show abstract

Walton, M.I., Eve, P.D., Hayes, A., Valenti, M.R., De Haven Brandon, A.K., Box, G., Hallsworth, A., Smith, E.L., Boxall, K.J., Lainchbury, M., et al. (2012). CCT244747 is a novel potent and selective CHK1 inhibitor with oral efficacy alone and in combination with genotoxic anticancer drugs. Clin cancer res, Vol.18 (20), pp. 5650-5661.  show abstract

Burrell, J.S., Walker-Samuel, S., Baker, L.C., Boult, J.K., Jamin, Y., Ryan, A.J., Waterton, J.C., Halliday, J. & Robinson, S.P. (2012). Evaluation of novel combined carbogen USPIO (CUSPIO) imaging biomarkers in assessing the antiangiogenic effects of cediranib (AZD2171) in rat C6 gliomas. Int j cancer, Vol.131 (8), pp. 1854-1862.  show abstract

Jamin, Y., Smyth, L., Robinson, S.P., Poon, E.S., Eykyn, T.R., Springer, C.J., Leach, M.O. & Payne, G.S. (2011). Noninvasive detection of carboxypeptidase G2 activity in vivo. Nmr biomed, Vol.24 (4), pp. 343-350.  show abstract

Faisal, A., Vaughan, L., Bavetsias, V., Sun, C., Atrash, B., Avery, S., Jamin, Y., Robinson, S.P., Workman, P., Blagg, J., et al. (2011). The aurora kinase inhibitor CCT137690 downregulates MYCN and sensitizes MYCN-amplified neuroblastoma in vivo. Mol cancer ther, Vol.10 (11), pp. 2115-2123.  show abstract

Boult, J.K., Walker-Samuel, S., Jamin, Y., Leiper, J.M., Whitley, G.S. & Robinson, S.P. (2011). Active site mutant dimethylarginine dimethylaminohydrolase 1 expression confers an intermediate tumour phenotype in C6 gliomas. J pathol, Vol.225 (3), pp. 344-352.  show abstract

Vaughan, L.S., Barker, K., Webber, H., Jamin, Y., Robinson, S., Guichard, S. & Chesler, L. (2011). AZD8055, a combined TORC1/TORC2 inhibitor regulates Mycn protein expression and prevents neuroblastoma growth in vitro and in vivo. Cancer research, Vol.71.

Vaughan, L.S., Barker, K., Webber, H., Jamin, Y., Robinson, S., Guichard, S. & Chesler, L. (2011). Abstract 4345: AZD8055, a combined TORC1/TORC2 inhibitor regulates Mycn protein expression and prevents neuroblastoma growth in vitro and in vivo. Tumor biology, .

Jamin, Y., Cullis, E.R., Vaughan, L., Koh, D.-., Chesler, L. & Robinson, S.P. (2010). Abstract 4189: Characterization of tumor progression and chemoresponse in a novel transgenic mouse model of neuroblastoma (TH-MYCN) using magnetic resonance imaging. Tumor biology, .

Gabellieri, C., Beloueche-Babari, M., Jamin, Y., Payne, G.S., Leach, M.O. & Eykyn, T.R. (2009). Modulation of choline kinase activity in human cancer cells observed by dynamic 31P NMR. Nmr biomed, Vol.22 (4), pp. 456-461.  show abstract

Jamin, Y., Gabellieri, C., Smyth, L., Reynolds, S., Robinson, S.P., Springer, C.J., Leach, M.O., Payne, G.S. & Eykyn, T.R. (2009). Hyperpolarized (13)C magnetic resonance detection of carboxypeptidase G2 activity. Magn reson med, Vol.62 (5), pp. 1300-1304.  show abstract

Robinson, S., Boult, J., Baker, L. & Jamin, Y. Investigating the Vascular Phenotype of Subcutaneously and Orthotopically Propagated PC3 Prostate Cancer Xenografts Using Combined Carbogen USPIO (CUSPIO) MRI. Topics in magnetic resonance imaging, .

Shah, A., Delgado-Goni, T., Casals Galobart, T., Wantuch, S., Jamin, Y., Leach, M., Robinson, S., Bamber, J. & Beloueche-Babari, M. Detecting human melanoma cell re-differentiation following BRAF or heat shock protein 90 inhibition using photoacoustic and magnetic resonance imaging. Scientific reports, .

Poon, E., Jamin, Y., Liang, T., Waltz, S., Kwok, C., Hakkert, A., Richards, M., Urban, Z., Thway, K., Zied, R., et al. Pharmacological blockade of MYCN in neuroblastoma using orally-bioavailable CDK inhibitors reveals an approach widely applicable to Myc-dependent cancers. Nature medicine, .  show abstract

Hill, D.K., Heindl, A., Zormpas-Petridis, K., Collins, D.J., Euceda, L.R., Rodrigues, D.N., Moestue, S.A., Jamin, Y., Koh, D.-., Yuan, Y., et al. Non-Invasive Prostate Cancer Characterization with Diffusion-Weighted MRI: Insight from In silico Studies of a Transgenic Mouse Model. Frontiers in oncology, Vol.7.

Vlachogiannis, G., Hedayat, S., Vatsiou, A., Jamin, Y., Fernandez Mateos, J., Khan, K., Lampis, A., Eason, K., Burke, R., Rata, M., et al. Patient-derived organoids model treatment response of metastatic gastrointestinal cancers. Science, .

Little, R.A., Jamin, Y., Boult, J.K., Naish, J.H., Watson, Y., Cheung, S., Holliday, K.F., Lu, H., McHugh, D.J., Irlam, J., et al. Mapping Hypoxia in Renal Carcinoma with Oxygen-enhanced MRI: Comparison with Intrinsic Susceptibility MRI and Pathology. Radiology, Vol.288 (3), pp. 739-747.  show abstract

Baker, L.C., Sikka, A., Price, J.M., Boult, J.K., Lepicard, E.Y., Box, G., Jamin, Y., Spinks, T.J., Kramer-Marek, G., Leach, M.O., et al. Evaluating Imaging Biomarkers of Acquired Resistance to Targeted EGFR Therapy in Xenograft Models of Human Head and Neck Squamous Cell Carcinoma. Frontiers in oncology, Vol.8.

Jamin, Y. MRI imaging of the hemodynamic vasculature of neuroblastoma predicts response to anti-angiogenic treatment. Cancer research, .


Conferences

Zormpas-Petridis, K., Failmezger, H., Roxanis, I., Blackledge, M.D., Jamin, Y. & Yuan, Y. (2018). Capturing Global Spatial Context for Accurate Cell Classification in Skin Cancer Histology., COMPAY/[email protected], Vol.11039, pp.52-60.

Guan, J., Danielson, L., Chand, D., Jamin, Y., Ruuth, K., Tucker, E., Umapathy, G., Wakil, A.E., Witek, B., Johnson, T.W., et al. (2016). Abstract B12: The ALK inhibitor PF-06463922 shows significant response as a single agent in ALK/MYCN driven models of neuroblastoma, Presented at Abstracts: AACR Special Conference: Advances in Pediatric Cancer Research: From Mechanisms and Models to Treatment and Survivorship; November 9-12, 2015; Fort Lauderdale, Florida, Targeted Therapeutics and Resistance, .

Li, J., Boult, J.K., Vinci, M., Popov, S., Barker, K., Ahmad, Z., Jamin, Y., Cummings, C., Eccles, S.A., Bamber, J.C., et al. (2015). Abstract 1488:In vivomagnetic resonance elastography in pediatric brain tumor models, Presented at Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA, Tumor Biology, .

Almeida, G.S., King, P., Jamin, Y., Hallsworth, A., Webber, H., Popov, S., Pearson, A.D., Chesler, L. & Robinson, S.P. (2015). Abstract 491: Tumor response to cabozantinib in the TH-MYCN GEM model of neuroblastoma, Presented at Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA, Tumor Biology, .

Papaevangelou, E., Almeida, G.S., Jamin, Y., Robinson, S.P. & deSouza, N.M. (2015). Abstract 2930: Differential tumour response to birinapant and irinotecan revealed by non-invasive MRI, Presented at Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA, Molecular and Cellular Biology, .

Boult, J., Li, J., Vinci, M., Jury, A., Popov, S., Jamin, Y., Cummings, C., Eccles, S., Bamber, J., Sinkus, R., et al. (2014). IMAGING THE TENSIONAL HOMEOSTASIS OF ORTHOTOPIC PAEDIATRIC GLIOMA XENOGRAFTS IN VIVO WITH MAGNETIC RESONANCE ELASTOGRAPHY, NEURO-ONCOLOGY, Vol.16, pp.48-49.

Jamin, Y., Glass, L., Hallsworth, A., George, R.E., Koh, D.-., Pearson, A.D., Chesler, L. & Robinson, S.P. (2013). Intrinsic susceptibility magnetic resonance imaging identifies tumors with ALKF1174L mutation in transgenic murine models of high-risk neuroblastoma., CANCER RESEARCH, Vol.73 (8).

Beloueche-Babari, M., Jamin, Y., Walker-Samuel, S., Smith, P.D., Waterton, J.C., Halliday, J., Barjat, H., Workman, P., Leach, M.O. & Robinson, S.P., et al. (2012). Non-invasive Imaging of Response to MEK Inhibition With Selumetinib (AZD6244, ARRY-142886) in a Human Colorectal Cancer Xenograft Using Diffusion-Weighted MRI, EUROPEAN JOURNAL OF CANCER, Vol.48, p.S202.

Jamin, Y., Cullis, E.R., Vaughan, L., Webber, H., Boult, J.K., Baker, L.C., Dow-Mu, K., Chesler, L. & Robinson, S.P. (2011). Abstract 5290: Imaging biomarkers of response to chemotherapy in neuroblastoma, Presented at Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL, Tumor Biology, .

Baker, L.C., Boult, J.K., Walker‐Samuel, S., Jamin, Y., Ashcroft, M.A. & Robinson, S.P. (2009). Abstract C90: An MRI and histological investigation of the acute response of orthotopic PC3 prostate tumors to the HIF pathway inhibitor NSC‐134754in vivo, Presented at Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics--Nov 15-19, 2009; Boston, MA, Other Therapeutic Agents, .

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