The Functional Proteomics Team is interested in solving questions about the biology underlying cancerous disease by studying molecular processes and pathways. To do this, the team use a range of techniques including mass spectrometry, biochemistry, molecular biology and informatics, to study protein function, proteome composition and organisation.
The team develops advanced mass spectrometry and novel proteomics techniques to further an understanding of cancer biology. Taking a multi-omics approach, the group examines both the genome and the proteome (entire set of expressed proteins) to investigate the heterogeneity of tumours.
Through its research and collaborations the group explores protein-protein interactions, cell signalling and protein expression to investigate cancer in a range of human tissues, cell lines, and model organisms.