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Functional Proteomics

Professor Jyoti Choudhary's team explores the molecular phenotype of cancer studying protein-protein interactions, signalling, post-translational modifications and protein expression.

Team leader

Professor Jyoti Choudhary

Professor Jyoti Choudhary

Team Leader

Professor Jyoti Choudhary's research focuses on the development and implementation of novel mass spectrometry and data analysis approaches for proteome discovery. She is Head of the Proteomics Core Facility and Career Faculty Leader of the Functional Proteomics Research Group.

ORCID 0000-0003-0881-5477

Team members

Dr Graeme Benstead-Hume
Dr Graeme Benstead-Hume
Senior Scientific Officer +44 20 7153 5119 ORCID 0000-0003-1478-3985

My research uses the graph topology features of genomics and proteomics data to highlight previously undiscovered interactions, functional modules and pathway changes. I use a range of machine learning and explorative statistics techniques. I completed my PhD as part of the Genome Damage and Stability Center (GDSC) at the University of Sussex. My background is in Artificial Intelligence and Computer Science.

Dr Gianluca Degliesposti
Dr Gianluca Degliesposti
Postdoctoral Training Fellow +44 20 3437 7054

I am a postdoc within Breast Cancer Research, embedded within the Functional Proteomics Lab. In my current research I’m developing new protocols for the analysis of cell surface proteomes from both experimental and clinical samples in the breast cancer settting. I’m working on small scale enrichment of plasma-membrane proteins, their identification, and quantification by isobaric tandem mass tag labelling. My previous research was focused on cross-linking and mass spectrometry as a proteomics tool for the structural investigation of protein-protein interactions in protein complexes. I completed my PhD at the University of Modena as part of the Molecular Modelling & Drug Design Lab.

Dr Theo Roumeliotis
Dr Theo Roumeliotis
Senior Scientific Officer +44 20 3437 7479

My research is focused on deep profiling of protein expression, post translational modifications and protein interactions in cancer by mass spectrometry. I am interested in the integration of multi-omics approaches to better understand how genomic alterations affect the function of the proteome with implications in patient classification and response to treatment.”

Liudmila Shcherbakova
Liudmila Shcherbakova
PhD Student

Liudmila obtained a BSc at King’s College London. She started her PhD at the ICR in October 2018 and is working on exploiting proteomic mass spectrometry analysis to understand the role of BAF chromatin remodelling complex in oncogenesis.

Sreejan Bandyopadhyay
Scientific Officer T +44 20 7153 5276
Dr Daniel Bode
Visiting Scientist
Gina Boot
Visiting Scientist
Lachlan Ellingboe
Summer Vacation Student
Zuza Kozik
Postdoctoral Training Fellow
Dr Chiara Marcozzi
Honorary Appointment
Miriam Melake
PhD Student T +44 20 7153 5239
Dr Mercedes Pardo Calvo
Senior Scientific Officer T +44 20 3437 7467
Dr Angela Paul
Senior Scientific Officer
Dr Bharath Sampadi
Postdoctoral Training Fellow T +44 20 3437 7026
Dr Fernando Jr Sialana
Postdoctoral Training Fellow T +44 20 3437 7645
Dr James Wright
Bioinfomatician T +44 20 3437 7455
Dr Lu Yu
Senior Scientific Officer