Professor Jyoti Choudhary's team explores the molecular phenotype of cancer studying protein-protein interactions, signalling, post-translational modifications and protein expression.
Professor Jyoti Choudhary's research focuses on the development and implementation of novel mass spectrometry and data analysis approaches for proteome discovery. She is Head of the Proteomics Core Facility and Career Faculty Leader of the Functional Proteomics Research Group.
My research uses the graph topology features of genomics and proteomics data to highlight previously undiscovered interactions, functional modules and pathway changes. I use a range of machine learning and explorative statistics techniques. I completed my PhD as part of the Genome Damage and Stability Center (GDSC) at the University of Sussex. My background is in Artificial Intelligence and Computer Science.
My research is focused on deep profiling of protein expression, post translational modifications and protein interactions in cancer by mass spectrometry. I am interested in the integration of multi-omics approaches to better understand how genomic alterations affect the function of the proteome with implications in patient classification and response to treatment.”
Liudmila obtained a BSc at King’s College London. She started her PhD at the ICR in October 2018 and is working on exploiting proteomic mass spectrometry analysis to understand the role of BAF chromatin remodelling complex in oncogenesis.