The Drug Discoverer

Professor Paul Workman reflects in depth on his experience in trying to drug a particularly challenging cancer target, and why it is always important to be clear about the risks and benefits of a drug discovery project – and to share the results with the research community.

Professor Paul Workman argues that creating drugs is a bit like climbing mountains – and as with scaling a craggy slope versus a smooth wall of rock, tackling some disease targets is easier than others.

With the publication of a monograph in her honour, in which he contributed an article, Professor Paul Workman celebrates the outstanding scientific achievements of the late Dr Susan Lindquist in the field of protein folding and its application to cancer and neurodegenerative disease. He also explains how her work has underpinned several of his drug discovery projects at the ICR.