Trying to drug the apparently undruggable, and what it can teach us 04 Nov 2020 Professor Paul Workman reflects in depth on his experience in trying to drug a particularly challenging cancer target, and why it is always important to be clear about the risks and benefits of a drug discovery project – and to share the results with the research community. Find out more Show/Hide
Climbing the peaks of drug discovery – tackling the most challenging targets with ingenuity and realism 21 Oct 2020 Professor Paul Workman argues that creating drugs is a bit like climbing mountains – and as with scaling a craggy slope versus a smooth wall of rock, tackling some disease targets is easier than others. Find out more Show/Hide
Book published in tribute to the late Dr Susan Lindquist – HSF1 and Molecular Chaperones in Biology and Cancer 24 Apr 2020 With the publication of a monograph in her honour, in which he contributed an article, Professor Paul Workman celebrates the outstanding scientific achievements of the late Dr Susan Lindquist in the field of protein folding and its application to cancer and neurodegenerative disease. He also explains how her work has underpinned several of his drug discovery projects at the ICR. Find out more Show/Hide
Understanding the off-target effects of cancer drugs – and how they could lead us to new forms of treatment 03 Mar 2020
Our manifesto for cancer drug discovery and development – focusing on innovation to tackle treatment resistance and meeting patients’ needs 30 Apr 2019
Why regulators must move with the science if we’re to get innovative new treatments to patients more quickly 05 Dec 2018