"It's been the start of a whole new life for me."
Watch how Karen O’Malley, from Fife in Scotland (pictured centre front with friends) is living well with advanced bowel cancer and pursuing her passion for wild swimming, thanks to a combination of chemotherapy and a targeted treatment.
What are cancer combination therapies?
Many cancer patients are treated with combination therapies. These therapies can combine two or more drugs or different types of therapy such as immunotherapy, chemotherapy and radiotherapy.
By discovering clever new combinations that aim to treat cancer in different ways, we hope we can stop cancer from developing resistance early on.
Why do we need combination therapies?
Drug resistance – where cancer adapts, evolves, and becomes resistant to treatment - is one of the biggest challenges we face in cancer research.
Over the years, our discovery of new targeted drugs has helped to improve the lives of cancer patients. But as cancer can become resistant to these drugs, we need to find ways to make them work harder.
One way we are doing this is by seeing if different combinations of treatments, either given at the same time, or in a certain sequence, will work better. This can involve treating patients with several drugs that work by different molecular mechanisms, or re-sensitising a cancer to an original treatment by giving the patient another therapy.
We need your donations to improve our understanding of the biology behind cancer, so we can find more combinations of treatments and help cancer patients have a better chance of surviving their cancer.