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Journal Articles

Ranes, M. Zaleska, M. Sakalas, S. Knight, R. Guettler, S. (2021). Reconstitution of the destruction complex defines roles of AXIN polymers and APC in β-catenin capture, phosphorylation, and ubiquitylation. , Vol.81 (16), pp. 3246-3261.e11.  show abstract

Pollock, K. Liu, M. Zaleska, M. Meniconi, M. Pfuhl, M. Collins, I. Guettler, S. (2019). Fragment-based screening identifies molecules targeting the substrate-binding ankyrin repeat domains of tankyrase. Scientific reports, Vol.9 (1), pp. 19130-?.  show abstract

Zaleska, M. Pollock, K. Collins, I. Guettler, S. Pfuhl, M. (2019). Solution NMR assignment of the ARC4 domain of human tankyrase 2. Biomolecular nmr assignments, Vol.13 (1), pp. 255-260.  show abstract

Xiong, S. Lorenzen, K. Couzens, A.L. Templeton, C.M. Rajendran, D. Mao, D.Y. Juang, Y.-. Chiovitti, D. Kurinov, I. Guettler, S. Gingras, A.-. Sicheri, F. (2018). Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment. Structure (london, england : 1993), Vol.26 (8), pp. 1101-1115.e6.  show abstract

Mariotti, L. Pollock, K. Guettler, S. (2017). Regulation of Wnt/β-catenin signalling by tankyrase-dependent poly(ADP-ribosyl)ation and scaffolding. British journal of pharmacology, Vol.174 (24), pp. 4611-4636.  show abstract

Pollock, K. Ranes, M. Collins, I. Guettler, S. (2017). Identifying and Validating Tankyrase Binders and Substrates: A Candidate Approach. Methods mol biol, Vol.1608, pp. 445-473.  show abstract

Mariotti, L. Templeton, C.M. Ranes, M. Paracuellos, P. Cronin, N. Beuron, F. Morris, E. Guettler, S. (2016). Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-β-Catenin Signaling. Molecular cell, Vol.63 (3), pp. 498-513.

Guettler, S. (2016). AXIN Shapes Tankyrase ARChitecture. Structure, Vol.24 (10), pp. 1625-1627.

Guettler, S. LaRose, J. Petsalaki, E. Gish, G. Scotter, A. Pawson, T. Rottapel, R. Sicheri, F. (2011). Structural basis and sequence rules for substrate recognition by Tankyrase explain the basis for cherubism disease. Cell, Vol.147 (6), pp. 1340-1354.  show abstract