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Research overview

Dr George Poulogiannis, Signalling & Cancer Metabolism team

The research focus of the Poulogiannis lab is to understand the signalling and metabolic networks that are related to cell growth and malignant transformation. In particular, we are interested in deciphering the genetic and molecular pathways that underlie metabolic addiction of cancer cells to known biosynthetic pathways and/or drive cancer cell adaptation to oxygen and nutrient deprivation. In line with these efforts, we aim to explore unique metabolic nodes for novel therapeutic intervention, biomarker selection, and personalized treatment.

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