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Professor Rosalind Eeles key publications


Boutros, PC., Fraser, M., Harding, NJ., de Borja, R., Trudel, D., Lalonde, E., Meng, A., Hennings-Yeomans, PH., McPherson, A., Sabelnykova, VY., et al. (2015) Spatial genomic heterogeneity within localized, multifocal prostate cancer. Nat Genet, Vol.47, pp.736–745, Show Abstract

Cooper, CS., Eeles, R., Wedge, DC., Van Loo, P., Gundem, G., Alexandrov, LB., Kremeyer, B., Butler, A., Lynch, AG., Camacho, N., et al. (2015) Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue. Nat Genet, Vol.47(4), pp.367–372, Show Abstract

Gillessen, S., Omlin, A., Attard, G., de Bono, JS., Efstathiou, E., Fizazi, K., Halabi, S., Nelson, PS., Sartor, O., Smith, MR., et al. (2015) Management of patients with advanced prostate cancer: Recommendations of the St.Gallen Advanced Prostate Cancer Consensus Conference (APCCC). Ann Oncol, Vol.26(8), pp.1589–1604, Show Abstract

Gundem, G., Van Loo, P., Kremeyer, B., Alexandrov, LB., Tubio, JM., Papaemmanuil, E., Brewer, DS., Kallio, HM., Högnäs, G., Annala, M., et al. (2015) The evolutionary history of lethal metastatic prostate cancer. Nature, Vol.520(7547), pp.353–357, Show Abstract

Kote-Jarai, Z., Mikropoulos, C., Leongamornlert, DA., Dadaev, T., Tymrakiewicz, M., Saunders, EJ., Jones, M., Jugurnauth-Little, S., Govindasami, K., Guy, M., et al. (2015) Prevalence of the HOXB13 G84E germline mutation in British men and correlation with prostate cancer risk, tumour characterisitics and clinical outcomes. Ann Oncol, Vol.26(4), pp.756–761, Show Abstract

Al Olama, AA., Kote-Jarai, Z., Berndt, SI., Conti, DV., Schumacher, F., Han, Y., Benlloch, S., Hazelett, DJ., Wang, Z., Saunders, E., et al. (2014) A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer. Nat Genet, Vol.46(10), pp.1103–1109, Show Abstract

Bancroft, EK., Page, EC., Castro, E., Lilja, H., Vickers, A., Sjoberg, D., Assel, M., Foster, CS., Mitchell, G., Drew, K., et al. (2014) Targeted Prostate Cancer Screening in BRCA1 and BRCA2 Mutation Carriers: Results from the Initial Screening Round of the IMPACT Study.  Eur Urol, Vol.66(3), pp.489–499, Show Abstract
Selected as the Best Fundamental Research Paper published in Eur Urol 2014

Cuzick, J., Thorat, MA., Andriole, G., Brawley, OW., Brown, PH., Culig, Z., Eeles, RA., Ford, LG., Hamdy, FC., Holmberg, L., et al. (2014) Prevention and early detection of prostate cancer. Lancet Oncol, Vol.15(11), pp.e484–492, Show Abstract

Lalonde, E., Ishkanian, AS., Sykes, J., Fraser, M., Ross-Adams, H., Erho, N., Dunning, MJ., Halim, S., Lamb, AD., Moon, NC., et al. (2014) Tumour genomic and microenvironmental heterogeneity for integrated prediction of 5-year biochemical recurrence of prostate cancer: a retrospective cohort study. Lancet Oncol, Vol.15(13), pp.1521–1532, Show Abstract

Tubio, JM., Li, Y., Ju, YS., Martincorena, I., Cooke, SL., Tojo, M., Gundem, G., Pipinikas, CP., Zamora, J., Raine, K., et al. (2014) Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes. Science, Vol. 345(6196), pp.1251343, Show Abstract

Eeles, RA., Al Olama, AA., Benlloch, S., Saunders, EJ., Leongamornlert, DA., Tymrakiewicz, M., Ghoussaini, M., Luccarini, C., Dennis, J., Jugurnauth-Little, S., et al. (2013) Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom gentotyping array. Nat Genet, Vol.45(4), pp.385–391, Show Abstract

Ruark, E., Seal, S., McDonald, H., Zhang, F., Elliot, A., Lau, K., Perdeaux, E., Rapley, E., Eeles, R., Peto, J., et al. (2013) Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14. Nat Genet, Vol.45(6), pp.686–689, Show Abstract

Tree, AC., Khoo, VS., Eeles, RA., Ahmed, M., Dearnaley, DP., Hawkins, MA., Huddart, RA., Nutting, CM., Ostler, PJ. & van As, NJ. (2013) Stereotactic body radiotherapy for oligometastases. Lancet Oncol, Vol.14(1), pp.e28–37, Show Abstract

Kote-Jarai, Z., Al Olama, AA., Giles, GG., Severi, G., Schleutker, J., Weischer, M., Canzian, F., Riboli, E., Key, T., Gronberg, H., et al. (2011) Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study. Nat Genet, Vol.43(8), pp.785–791, Show Abstract

Al Olama, AA., Kote-Jarai, Z., Giles, GG., Guy, M., Morrison, J., Severi, G., Leongamornlert, DA., Tymrakiewicz, M., Saunders, E., Hopper, JL., et al. (2009) Multiple loci on 8q24 associated with prostate cancer susceptibility. Nat Genet, Vol.41(10), pp.1058–1160, Show Abstract

Eeles, RA., Kote-Jarai, Z., Al-Olama,  AA., Giles, G., Guy, M., Severi, G.,  Muir, K., Hopper, JL., Henderson,  BE., Haiman, CA., et al. (2009) Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. Nat Genet, Vol.41(10), pp.1116–1121, Show Abstract

Eeles, R., Giles, G., Neal, D., Hamdy, F., Donovan, J., Muir, K. & Easton, D. (2008) SNPs in the kallikrein gene region associated with prostate cancer risk: true cause or association by design?: Reply to "Variation in KLK genes, prostate-specific antigen and risk of prostate cancer". Nat Genet, Vol.40(9)Show Abstract

Eeles, RA., Kote-Jarai, Z., Giles, GG., Olama, AA., Guy, M., Jugurnauth, SK., Mulholland, S., Leongamornlert, DA., Edwards, SM., Morrison, J., et al. (2008) Multiple newly identified loci associated with prostate cancer susceptibility. Nat Genetics, Vol. 40(3), pp.316–321, Show Abstract

Vergis, R., Corbishley, CM., Norman, AR., Bartlett, J., Jhavar, S., Borre, M., Heeboll, S., Horwich, A., Huddart, R., Khoo, V., et al. (2008) Intrinsic markers of tumour hypoxia and angiogenesis in localised prostate cancer predict the outcome of radical treatment: analysis of two randomised radiotherapy trials and one surgical cohort study. Lancet Oncol, Vol.9(4), pp.342–351, Show Abstract

Dearnaley, DP., Sydes, MR., Graham, JD., Aird, EG., Bottomley, D., Cowan, RA., Huddart, RA., Jose, CC., Matthews, JH., Millar, J., et al. (2007) Escalated-dose versus standard-dose conformal radiotherapy in prostate cancer: first results from the MRC RT01 randomised controlled trial. Lancet Oncol, Vol.8(6), pp.475–487, Show Abstract