CLOSED Early-Onset Breast Cancer Risk: Age-Specific Genetic Susceptibility and Prediction in Diverse Populations

Primary supervisor: Professor Montse Garcia-Closas Primary site: Sutton Funded by Marie Skłodowska-Curie Actions (MSCA) Doctoral Networks

CLOSED Modifiable Risk Factors and Cancer Burden in the UK: Trends, Impact, and Prevention Opportunities

Primary supervisor: Professor Montse Garcia-Closas Primary site: Sutton Funded by CRUK CD3 Programme

CLOSED: Structural dissection of β-catenin ubiquitylation by cryo-electronmicroscopy

Primary supervisor: Professor Sebastian Guettler Primary site: Chelsea Funded by CRUK

CLOSED: Regulation of the β-catenin destruction complex by deubiquitylation

Primary supervisor: Professor Sebastian Guettler Primary site: Chelsea Funded by CRUK

CLOSED: Optimising radiotherapy dose-fractionation and volume for maximal synergy with immunotherapy

Primary supervisor: Dr Navita Somaiah, Dr Erik Wennerberg Primary site: Sutton Funded by CRUK RadNet

CLOSED: Towards non-invasive monitoring and prediction of cancer evolutionary dynamics from cfDNA

Primary supervisor: Professor Trevor Graham Primary site: Sutton Funded by Horizon Europe MSCA Doctoral Network 2025

CLOSED: New strategies for exploiting the fitness costs of drug resistance in cancer

Primary supervisor: Professor Trevor Graham Primary site: Sutton Funded by Horizon Europe MSCA Doctoral Network 2025

CLOSED: Targeting Urea Cycle Dysregulation as a Tumour Specific Vulnerability in Lethal Prostate Cancer

Primary supervisor: Dr Alec Paschalis Primary site: Sutton Funded by ICR

CLOSED: The Multiscale Vulnerability Map: Cross-Discipline Multimodal Mining Reveals Colorectal Cancer's Hidden Weak Points

Primary supervisor: Professor Anguraj Sadanandam Primary site: Sutton Funded by MRC iCASE Award (Merck)

CLOSED: Comprehensive multi-omics profiling of “islands of resistance” tumour cells to uncover aromatase inhibitor resistant subclones in oestrogen receptor positive breast cancer

Primary supervisor: Dr Maggie Cheang Primary site: Sutton Funded by MRC iCASE award (AstraZeneca)

CLOSED: Exploiting lineage-specific dependencies in paediatric-type diffuse high-grade glioma.

Primary supervisor: Professor Chris Jones Primary site: Sutton Funded by Medical Research Council - Doctoral Training Partnership (MRC DTP)

CLOSED: Development of the next generation circulating tumour DNA tests in gastrointestinal cancers

Primary supervisor: Professor Michael Hubank Primary site: Sutton Funded by NIHR

CLOSED: Cell cycle regulation of the WEE1 kinase

Primary supervisor: Professor Jonathon Pines Primary site: Chelsea Funded by Medical Research Council - Doctoral Training Partnership (MRC DTP)

CLOSED: Deciphering cancer cell dependency on eIF4E

Primary supervisor: Dr Paul Clarke Primary site: Sutton Funded by Medical Research Council - Doctoral Training Partnership (MRC DTP)

CLOSED: Targeting AMPK as a metabolic vulnerability of metastatic cancer cells

Primary supervisor: Professor Joanna Loizou Primary site: Sutton Funded by ICR

CLOSED: Typos in the genome: Defining the molecular mechanism of replication slippage

Primary supervisor: Dr Gideon Coster Primary site: Chelsea Funded by Medical Research Council - Doctoral Training Partnership (MRC DTP)