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New computational breakthrough helps uncover how water molecules influence cancer drug potency
In a major step forward for cancer drug discovery, researchers have demonstrated how computational simulations can unravel the complex role of water molecules in drug binding, potentially saving years of trial and error in the lab.
Embracing mathematics is key to illuminating cancer cell evolution
A new review explains how turning to mathematics is helping researchers decode one of cancer’s most elusive traits: its ability to evolve and adapt.
New combination treatment could overcome immunotherapy resistance in difficult-to-treat cancers
A pioneering clinical trial has demonstrated for the first time that two existing treatments can be combined to potentially improve outcomes for sarcoma and melanoma patients with advanced tumours in their limbs.
Bowel cancer’s 'big bang' moment revealed
Like the astronomical explosion that kickstarted the universe, bowel cancer has a 'Big Bang' moment which determines how it will grow, according to new research from scientists at The Institute of Cancer Research, London.
Scientists discover new weakness in drug-resistant sarcomas, offering hope for smarter treatment strategies
In a major step forward for cancer research, scientists have uncovered a surprising vulnerability in soft tissue sarcomas – a rare and aggressive group of cancers that affect the soft tissues of the body, such as muscle, fat and blood vessels.
International trial shows combination immunotherapy treatment significantly improves survival in high-risk kidney cancer patients
Combination immunotherapy treatment significantly improves disease-free survival following surgery in patients with the most common type of kidney cancer, according to new research.
Global study challenges ‘cancer epidemic’ in young adults – except for bowel cancer
Cancer cases in both younger and older adults are increasing, challenging the idea that a global rise is only occurring in the under 50s, a major new analysis by The Institute of Cancer Research, London, has found.
Targeted drug prolongs survival in breast cancer patient group
Patients with HR+ and HER2- node positive high-risk early breast cancer experience improved long term overall survival seven years on, following two years of taking a targeted drug alongside standard hormone therapy, according to new research.
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‘Smart jab’ shows promise in treating advanced head and neck cancer
A new type of cancer treatment which is given via an injection under the skin has shown early signs of success in patients with advanced head and neck cancer.
New drug shows dramatic effect in shrinking lung cancer tumours
A new drug is having a dramatic effect on shrinking lung cancer tumours, according to new research.
MRI scan before bladder cancer surgery shown to save lives
Giving patients with suspected bladder cancer an MRI scan before surgery could mean they would be treated more quickly, leading to fewer deaths due to the disease, new ICR-led research suggests.
Men with BRCA1 and BRCA2 gene mutations should get annual prostate cancer screening
Prostate cancer guidelines should change so that all men from the age of 40 with mutations in either the BRCA1 or BRCA2 gene are offered regular PSA testing to detect early signs of the disease, experts are urging.