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AI-generated DNA helix
Targeting cancer cell DNA repair mechanism may make radiotherapy more effective

19/06/26

Scientists have uncovered a mechanism that helps cancer cells survive radiation, pointing to a potential new way to make treatment more effective.
Silver sheets of drugs
ICR welcomes FDA approval of capivasertib for advanced prostate cancer

18/06/26

The Institute of Cancer Research, London, strongly welcomes the news that the targeted drug capivasertib, has been approved by the US Food and Drug Administration (FDA) for treating a type of advanced prostate cancer.
Radiotherapy IMRT (photo: Jan Chlebik/the ICR)
Thousands of men with prostate cancer will now be offered high-powered radiotherapy on the NHS

18/06/26

Thousands of men with prostate cancer in England will be offered a more precise form of radiotherapy that cuts treatment time by up to 75 per cent, based on the results of a trial led by The Institute of Cancer Research (ICR), London and Royal Marsden NHS Foundation Trust. The therapy is known as SABR or SBRT.
Hand holding magnifying lens pointing at group of different coloured illustrated figures
Cancer trials under the microscope: Study finds barriers to inclusion persist in the UK

08/06/26

A new UK-based study is shedding light on a quiet but consequential problem in cancer research: whether some people have less opportunity than others to participate in clinical trials.
Image of immunofluorescence staining of bladder tumour tissue. Some areas appear lighter green, some dark blue, and others black.
Immunotherapy boost can spare more bladder cancer patients major surgery

02/06/26

An immunotherapy helps bladder cancer patients remain cancer free and enables them to avoid surgery, a phase II trial has found.
Histopathologic image illustrating squamous cell carcinoma.
Immunotherapy injection shrinks tumours in patients with recurrent and/or metastatic head and neck cancer

31/05/26

A targeted cancer treatment given via a simple injection under the skin shrank tumours in more than one third of patients with recurrent and/or metastatic head and neck cancer whose disease has stopped responding to standard treatments, according to research led by scientists at The Institute of Cancer Research, London
Image of pill bottle with pills spilling out
New targeted therapy shrinks advanced gastrointestinal tumours for 61 per cent of patients in an early study

30/05/26

A new, targeted cancer therapy for advanced gastrointestinal stromal tumours (GIST) has shown promising early results, with 61 per cent of patients who received velzatinib as first-line treatment experiencing tumour shrinkage of 30 per cent or over. The results could pave the way for a larger trial to evaluate this therapy as a first-line alternative to imatinib, which has been the standard treatment for more than two decades.
Big Bang moment in bowel cancer research
Targeted therapy shows promise for patients with advanced colorectal cancer in a first-in-human study

30/05/26

A targeted antibody therapy combined with standard chemotherapy has shown early signs of tumour shrinkage and disease control in patients with advanced bowel cancer, according to new Phase I clinical trial results from The Institute of Cancer Research, London and The Royal Marsden NHS Foundation Trust.
A fluorescence microscope image of Xenopus cancer kidney cells in interphase
Combination immunotherapy significantly reduces kidney cancer recurrence after surgery

30/05/26

Results from the international Phase III RAMPART trial were presented today at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting by researchers from The Institute of Cancer Research, London and The Royal Marsden NHS Foundation Trust.
Radiotherapy machine at The Royal Marsden Hospital (photo: Jan Chlebik/the ICR)
One week radiotherapy course shown to be safe and effective in the long term for early stage breast cancer

20/05/26

A one-week course of post-surgery radiotherapy is just as safe and effective as the traditional three-week course for people with early-stage breast cancer, according to long-term results from a ground-breaking study, led by The Institute of Cancer Research, London
triple negative breast cancer cell
Early scan could help predict breast cancer treatment response

19/05/26

Research led by The Institute of Cancer Research, London and King’s College London suggests that an early scan taken after one cycle of chemotherapy could help to predict how well a patient’s cancer will respond to treatment.
MR Linac
Men can be safely treated with two radiotherapy sessions for localised prostate cancer with no increase in side effects in comparison to five sessions

17/05/26

Men with localised prostate cancer could benefit from a shorter course of radiotherapy, after new research data shows that just two higher-dose treatments are as safe as a standard five-session regimen, with no increase in side effects.