Researcher holding up a culture dish in each hand

Search newsletter

What's inside? See our first ever special edition of Search which is in addition to our twice-yearly newsletters. 

In this special summer edition of Search, we take an in depth look at the work our scientists are doing in bringing new treatments to people with cancer, who are at the heart of everything we do. 

You can find out more about the importance of understanding the biology of cancer. By unravelling cancer’s secrets, our scientists will have a better idea of how cancer develops, spreads and becomes resistant to treatment, which will help them find new ways to prevent and treat the disease. 

We then dive into drug discovery, explaining why protein degradation has the potential to lead to new treatments for hard-to-treat cancers and showcasing a recent advance that will help our structural biologists make further discoveries.

For instant access to our latest special issue of Search, simply subscribe by completing the form below. 

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"I look forward to getting my copy of Search. It’s great to read all about the excellent work that the ICR does and it reminds me why I decided to support them in the first place."
- James Wilding, donor

Newsletter archive

Search issue 51 - Spring 2025

Find out how our scientists are developing improved breast cancer tools that will help identify women at high risk and our pioneering trial to test multiple treatments for brain cancer.

Download issue 51 (PDF)

Search issue 50 - Autumn 2024

In our 50th edition of the Autumn Search issue, we look at the latest research news featuring a new breast cancer drug approval in the UK, for treating the most common type of advanced breast cancer.

Download issue 50 (PDF)

Search issue 49 – Spring 2024

Look at how our researchers received a prestigious Queen's Anniversary Prize on behalf of the ICR, in recognition of our transformational breast cancer research programme.

Download issue 49 (PDF)

Search issue 48 – Autumn 2023

Find out how we're transforming treatment for people with cancers of unmet need, and meet our family charity partner Siobhan's Superstar Legacy, whose generous donation is supporting the work of our new Team Leader in Developmental Oncology, Dr Sally George.

Download issue 48 (PDF)

Search issue 47 – Spring 2023

Meet Dr Stephen-John Sammut, whose research uses AI to forecast how cancer is likely to respond to treatment, and find out more about capivasertib, a new promising drug born from the ICR’s cutting-edge science and pioneering programme of clinical trials.

Download issue 47 (PDF)

Search issue 46 – Autumn 2022

Meet the Director of our Centre for Evolution and Cancer, Professor Trevor Graham, whose research uses evolutionary principles and computational modelling to reveal how cancer develops.

Download issue 46 (PDF)

Search issue 45 – Spring 2022

Meet our new Team Leader, Dr Alex Radzisheuskaya, whose research focusses on how proteins help to package up DNA in cells – and the role that this can play in cancer.

Download issue 45 (PDF)

 

A picture of an MRI scanner
New MRI scan can spot tiny traces of blood cancer after treatment

04/08/25

Whole-body MRI scans provide powerful insights into treatment effectiveness and long-term outcomes for patients with myeloma, an incurable but treatable blood cancer.  Results from the iTIMM study led by The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, London have shown that whole-body MRI scans (WB-MRI) can detect tiny traces of the disease, known as minimal residual disease (MRD), in the bone marrow after treatment. This can provide a crucial insight into how well patients with multiple myeloma are responding to treatment and whether they might relapse - offering a potential new standard in how this complex blood cancer is assessed. 
Small fragments, big impact: discovering the 'shearosomes' that drive cancer's spread

30/07/25

A collaborative study reveals an unexpected way cancer spreads through the body – by shedding tiny, previously unidentified fragments called shearosomes as tumour cells squeeze through narrow blood vessels. Shearosomes appear to actively influence their surroundings, supporting the growth of secondary tumours, offering new insights into how cancer spreads.
Turning cancer’s weakness into a weapon: 20 years of PARP inhibitors and BRCA research

29/07/25 - Robbie Lockyer

Two decades ago, a pivotal exchange between two scientists sparked a scientific and medical revolution. Professor Alan Ashworth, then Director of the Breast Cancer Now Toby Robins Research Centre at The Institute of Cancer Research, London, and his collaborator Professor Steve Jackson had long known that inherited genetic mutations in the genes BRCA1 and BRCA2 increase the risk of cancer. But, they wondered, what if those same mutations could be turned against the cancer itself?