Translational Sarcoma, Melanoma and Rare Tumour Surgery Group

Mr Myles Smith's group aims to translate basic science innovations generated at the ICR to advance the surgical treatment of cancer – for example, evaluating molecular markers to aid the definition of cancer at the time of surgery.


Our group aims to help the translation of imaging technologies developed at The Institute of Cancer Research to the clinic and bedside.

Tumour-specific preoperative and intraoperative imaging with targeted molecular probes holds great promise in cancer surgery. Improved ability to define the distribution of cancer at the time of surgery would better help define the extent and adequacy of resection, while minimising excision of healthy tissue.

Other benefits include intraoperative staging and the guidance of adjuvant treatments. Successful application of intraoperative targeted molecular imaging to cancer surgery has the potential to translate into improved local control and survival, while reducing the impact of curative interventions. We aim to help the translation of imaging technologies developed at The Institute of Cancer Research to the clinic and bedside.

Myles Smith

Honorary Faculty:

Translational Sarcoma, Melanoma and Rare Tumour Surgery Mr Myles Smith

Myles Smith is a Consultant General Surgeon and Surgical Oncologist. After completing his surgical training through the Royal College of Surgeons in Ireland's Higher Surgical Training scheme, he pursued a General Surgical Oncology Fellowship at the University of Toronto. He joined The Royal Marsden NHS Foundation Trust in 2015, where he focuses on sarcoma and melanoma treatment.

Recent discoveries from this group

09/03/26

Researchers have developed a new preclinical platform for studying aggressive childhood brain tumours, using advanced imaging to show how closely experimental models mirror the disease seen in patients.
King Charles presenting Professor Kristian Helin with the Queen Elizabeth Prize

24/02/26

Researchers from The Institute of Cancer Research, London, attended a prestigious ceremony at St James’s Palace today to mark the formal presentation of the Queen Elizabeth Prize for Higher and Further Education (previously known as the Queen’s Anniversary Prize).
Illustration of scaffolding complex

11/02/26

A team of scientists at The Institute of Cancer Research, London, has developed a repeatable three-dimensional (3D) imaging technique that could transform preclinical cancer studies.
Artificial brain with high-tech-looking background

28/01/26

The Institute of Cancer Research, London, is the joint recipient of a major new Medical Research Council (MRC) grant to advance how sensitive medical imaging data can be used for research.