News and features
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New cancer drug shows signs of promise in early-stage trial
A drug which can block the activity of a common mutation in cancer has shown promise in its first patient trial, a new study reports.
Science Writing Prize 2014 – Using crystals to cure cancer
Each year, the ICR runs a science writing competition among our scientists and students – and here is 2014’s winning piece.

ICR to collaborate with Merck Serono and Wellcome Trust to co-develop anti-cancer drugs
Merck Serono, The Institute of Cancer Research (ICR), and the Wellcome Trust, London, today announced a co-development and license agreement building on two independent research programs at both the ICR and Merck Serono to identify inhibitors of tankyrase, an enzyme of the poly (ADP-ribose) polymerase family.

Chemotherapy regimen shows promise against testicular cancer
A combination of chemotherapy drugs has shown promise in a group of patients with testicular cancer and other germ cell tumours who currently have a poor prognosis.
DNA in ‘gene deserts’ linked with breast cancer
Long stretches of DNA that contain no genes at all can affect the risk of breast cancer, by physically interacting with genes elsewhere, a new study reports.

Statement in response to NICE approval of dabrafenib for the treatment of certain cases of advanced melanoma
Professor Paul Workman comments on final draft guidance from NICE recommending dabrafenib for the treatment of advanced melanoma which tests positive for the BRAF V600 mutation.

Blood test could identify when cancer treatment has become detrimental
Some treatments for prostate cancer, while initially effective at controlling the disease, not only stop working over time but actually start driving tumour growth, a major new study shows.

Genetic testing can identify men at six-fold increased risk of prostate cancer
Scientists can now explain a third of the inherited risk of prostate cancer, after a major international study identified 23 new genetic variants associated with increased risk of the disease.
Location of cancer’s growth affects treatment effectiveness
A new study by scientists at the ICR, showed that mice with melanoma responded differently to a viral therapy depending on where in the body their tumours developed.

Statement in response to the Government's decision to increase the Cancer Drugs Fund
Our Interim Chief Executive, Professor Paul Workman, comments on the Government's decision to increase the Cancer Drugs Fund from £200m a year to £280m a year
New tool to probe cancer’s molecular make-up
Scientists have shown how to better identify and measure vital molecules that control cell behaviour – paving the way for improved tools for diagnosis, prediction and monitoring of cancer.
Risk of premature menopause after cancer treatment mapped
Women treated for the cancer Hodgkin lymphoma will be able to better understand their risks of future infertility after researchers estimated their risk of premature menopause with different treatments.
