News and features
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Computer-controlled table could direct radiotherapy to tumours
Sophisticated computer modelling could be used to deliver high doses of radiotherapy to tumours more quickly than current methods

Highlights of 2013
We review ten of the most exciting discoveries made in the past year.
ICR research team wins award for improving quality of life for cancer patients
A clinical trials team at The Institute of Cancer Research, London, has won a top award for its work to improve quality of life for people with head and neck cancers.
Beating breast cancer’s resistance to hormone treatments
Professor Clare Isacke discovered that a signalling pathway in ER-positive breast cancer that is linked to resistance to aromatase inhibitors in some cancers.

Pinpointing the first founder mutations that lead to leukaemia
Professors Mel Greaves and Richard Houlston were able to identify the exact mutations that kick-start cancer, potentially enabling more effective targeted therapies.
Pioneering cancer drugs could treat many more patients – by targeting new gene defect
A pioneering new class of targeted cancer drug could benefit many more patients than previously thought including some with ovarian, stomach, bladder, cervical and prostate cancer.

ICR researchers visit Westminster to see science policy making in action
Last week, two of our researchers here at The Institute of Cancer Research, London, spent a week in Westminster as part of the Royal Society MP Pairing Scheme.

Discovering an intriguing gene link to breast and ovarian cancer
Professor Nazneen Rahman's team found gene mutations linked to an increased risk of breast and ovarian cancer, in what may be a new mechanism of cancer development.
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Identifying the genetic driver of childhood glioblastoma
Dr Chris Jones uncovered the genetic causes of a rare but lethal form of childhood brain cancer, improving our understanding of the development of the disease.

Unlocking the hidden potential of cutting-edge cancer drugs
Professor Paul Workman and collaborators uncovered a hidden mechanism revealing how a class of cutting-edge cancer drugs attack tumours.
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Stopping cancer in its tracks
Dr Chris Bakal and his team pinpointed a set of genes that allows melanoma cells to change rapidly between two shapes in order to escape from the skin and spread around the body.

Quantifying breast cancer risk after lymphoma treatment
Professor Tony Swerdlow and colleagues reported on the world’s largest cohort study into factors affecting the risk of breast cancer after treatment with radiotherapy for Hodgkin lymphoma.
