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Search newsletter

What's inside? See our first ever special edition of Search which is in addition to our twice-yearly newsletters. 

In this special summer edition of Search, we take an in depth look at the work our scientists are doing in bringing new treatments to people with cancer, who are at the heart of everything we do. 

You can find out more about the importance of understanding the biology of cancer. By unravelling cancer’s secrets, our scientists will have a better idea of how cancer develops, spreads and becomes resistant to treatment, which will help them find new ways to prevent and treat the disease. 

We then dive into drug discovery, explaining why protein degradation has the potential to lead to new treatments for hard-to-treat cancers and showcasing a recent advance that will help our structural biologists make further discoveries.

For instant access to our latest special issue of Search, simply subscribe by completing the form below. 

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Newsletter archive

Search issue 51 - Spring 2025

Find out how our scientists are developing improved breast cancer tools that will help identify women at high risk and our pioneering trial to test multiple treatments for brain cancer.

Download issue 51 (PDF)

Search issue 50 - Autumn 2024

In our 50th edition of the Autumn Search issue, we look at the latest research news featuring a new breast cancer drug approval in the UK, for treating the most common type of advanced breast cancer.

Download issue 50 (PDF)

Search issue 49 – Spring 2024

Look at how our researchers received a prestigious Queen's Anniversary Prize on behalf of the ICR, in recognition of our transformational breast cancer research programme.

Download issue 49 (PDF)

Search issue 48 – Autumn 2023

Find out how we're transforming treatment for people with cancers of unmet need, and meet our family charity partner Siobhan's Superstar Legacy, whose generous donation is supporting the work of our new Team Leader in Developmental Oncology, Dr Sally George.

Download issue 48 (PDF)

Search issue 47 – Spring 2023

Meet Dr Stephen-John Sammut, whose research uses AI to forecast how cancer is likely to respond to treatment, and find out more about capivasertib, a new promising drug born from the ICR’s cutting-edge science and pioneering programme of clinical trials.

Download issue 47 (PDF)

Search issue 46 – Autumn 2022

Meet the Director of our Centre for Evolution and Cancer, Professor Trevor Graham, whose research uses evolutionary principles and computational modelling to reveal how cancer develops.

Download issue 46 (PDF)

Search issue 45 – Spring 2022

Meet our new Team Leader, Dr Alex Radzisheuskaya, whose research focusses on how proteins help to package up DNA in cells – and the role that this can play in cancer.

Download issue 45 (PDF)

 

06/09/25

The Institute of Cancer Research, London, and The Royal Marsden NHS Foundation Trust have teamed up with Sir Chris Hoy and PureGym to launch a collaboration to encourage men with prostate cancer to be more active.

The partnership was launched today, at a PureGym in Glasgow, by six-time Olympic gold medallist Sir Chris Hoy,  PureGym CEO Clive Chesser, and Professor Nick James of the Institute of Cancer Research (ICR) ahead of Sir Chris’s Tour De 4 charity bike ride.

It will see experts at The ICR and The Royal Marsden provide a structured exercise programme, including a free one-year membership at PureGym, for men with advanced prostate cancer on hormone therapy.

Advanced prostate cancer affects around 20,000 men in the UK each year. The main treatment is hormone therapy – side effects include weight gain driven by increase in body fat and muscle loss, fatigue and psychological changes. Long term, these treatments increase the risk of bone thinning, heart disease and diabetes.

Are you on hormone therapy as part of your prostate cancer treatment? You could be suitable for a free PureGym membership and a structured exercise programme.

Register your interest

Exercise can improve quality of life

Research has shown that exercise can result in a better quality of life for men on hormone therapy, with less fatigue, lower body fat and higher muscle mass, and improved bone density. NHS guidelines recommend that men with advanced prostate cancer are offered exercise programmes.

However, few programmes are available, and figures show that around a third of men with advanced prostate cancer are completely inactive and only around one in eight meet guideline levels of activity.

Understanding barriers to exercise

Financial pressures, fatigue, coping with a major illness, and lack of knowledge about how to begin exercising safely, are all recognised as major barriers stopping men with prostate cancer from exercising. This initiative aims to address this.

Professor Nick James, Professor of Prostate and Bladder Cancer Research at The Institute of Cancer Research, London, and Consultant Clinical Oncologist at The Royal Marsden NHS Foundation Trust. He says:

“A diagnosis of advanced cancer is devastating. I frequently hear patients being advised by their families that they must take it easy and not overexert themselves whereas in most cases, this advice, while well-meaning is not usually true. In fact, the opposite is true.

“There is growing evidence that exercise, as well as improving general well-being, might also directly improve cancer outcomes. Some studies have shown that exercising is so effective that if it was a drug, we would call it a ‘breakthrough’. However, while prostate cancer patients may be advised about the importance of exercise, they are rarely supported to actually begin – or simply continue – exercising safely.

“Joining a gym, particularly when you are older and recently diagnosed with a major illness, is clearly a major psychological hurdle. It’s also a financial barrier for many people, so we’re delighted to partner with PureGym to offer men with locally advanced or metastatic prostate cancer who are on hormone therapy this free access to gym facilities. Alongside this, we will provide a structured exercise programme, which can be undertaken at home or in the gym, with the aim of supporting men to build a regular exercise habit that could improve their quality of life and overall health.”

Sir Chris Hoy says:

“This is a groundbreaking partnership and initiative which demonstrates the power of the Tour De 4, what it can achieve and the legacy it will leave.

“Scientific studies have shown that structured exercise is the perfect complement to many cancer treatments, but we need to break down the barriers that often prevent patients getting consistent and regular physical activity to experience these benefits.

“Exercise has been a fundamental part of my life and never more so than since my diagnosis of prostate cancer. I find it hugely encouraging that the importance of exercise for prostate cancer is being recognised. This is a significant step forward and potentially transformative.

“I have a long-standing association with PureGym which, more than any fitness organisation in the UK, has the scale, reach and capability to make a demonstrable national impact. I look forward to seeing the results of this initiative in the coming months and years.”

Clive Chesser CEO of PureGym says:

“Prostate cancer, the most common cancer among men, is a terrible disease with nearly 50k diagnosed with it each year. For a number of reasons many of these men are not as active as they could be and we want this to change, which is why I am delighted to be announcing this partnership, enabled by our national reach and scale as the UK’s largest gym company. We hope that offering free membership to advanced prostate cancer sufferers will enable thousands, across the country, to benefit from regular exercise with expert guidance from The Institute of Cancer Research and The Royal Marsden.

“As Sir Chris Hoy, with whom we have a long association, has so bravely shown staying active is a great way of managing the disease both mentally and physically and we are proud to be supporting him with his vital mission.”

The initiative

Men with locally advanced or metastatic prostate cancer, on hormone therapy, will be eligible for:

  • Free one-year PureGym membership
  • 26-week exercise programme with videos that can be followed either at home or in the gym, alongside information and resources to support you in your treatment journey.

The exercise programme has been specifically designed for men with prostate cancer that has spread beyond the prostate into the surrounding tissues or has spread to more distant parts of the body. The programme considers fatigue, lower bone density, and risks associated with having prostate cancer that has spread to the bones.

To register your interest in taking part, and for more information, visit icr.ac.uk/puregym