Study and Careers

Department/Directorate Information: Division of Clinical Studies - Clinical Trials and Statistics Unit (ICR-CTSU) The ICR-CTSU is a Cancer Research UK-funded, internationally recognised methodologist led clinical trials unit, providing cancer-focused clinical trial research expertise. We lead pioneering, efficient, high-quality, and impactful trials across the phases. Our expertise ranges from experimental medicine early phase studies exploring biological efficacy to trials which may deliver widespread change to routine practice, underpinned by applied methodology to drive forward clinical trial innovation. See our clinical trials Role Summary The Group Leader will lead a component of ICR-CTSU’s portfolio of clinical trials research. The post holder will join an existing faculty and seek to further develop and grow the portfolio in line with ICR-CTSU’s overall strategy; taking responsibility for a number of ongoing trials as well as the development of new trials. There will be the opportunity to develop and grow a team including the potential for a Postdoctoral Training Fellow and/ or a Trial Manager. We seek an experienced statistician / biostatistician with a strong research interest in clinical trials methodology and a passion for direct involvement in the oversight and leadership of academic clinical trials. The successful candidate will work closely with the Director of ICR-CTSU to further enhance the Unit’s internationally recognised strength in clinical trial design, conduct and analysis. The post holder will be expected to make a substantial independent intellectual contribution to clinical trials projects and be proactive in leading and contributing to broad initiatives that enhance the overall effectiveness of ICR-CTSU. The appointee will contribute to the overall scientific life of the ICR including the newly established ICR/Royal Marsden Hospital’s Centre for Trials and Population Data Science, by providing mentorship to more junior colleagues and acting as an academic leader. We seek an individual who will work closely and collaboratively with other faculty/Group Leaders at the ICR and with international/national key opinion leaders to extend the breadth and depth of ICR-CTSU’s biologically rich clinical trials portfolio. In partnership with clinical opinion leaders, this individual will generate research funds to conduct and deliver clinical trials research at the international forefront. Presentation at national and international conferences, production of top-quality research outputs and substantial professional contribution to wider clinical trial network bodies are expected. Enthusiasm for team-based science in a collaborative interdisciplinary environment is essential. The appointment will be based on track record and the ability and willingness to engage in team science. The successful appointee will have access to ICR’s successful PhD training programme and core facilities. Key Requirements Higher degree (MSc or PhD) in medical statistics/biostatistics or an allied field (e.g. public health, epidemiology, data science) with relevant work experience Significant experience as a clinical trials, medical statistician or bio-statistician within the academic or commercial sector; a blend of both would be highly desirable A desire to apply existing and novel statistical methods to the requirements of a diverse range of statistical problems A broad understanding of cancer research Ability to lead a Clinical Trials Unit based research group As part of your online application, you will be required to upload your full CV which will pre-populate your application form, you will also be asked to attach the following documents and failure to do so will mean your application cannot be considered on this occasion: Lists of major publications, achievements, research grants and distinctions. A PDF of a maximum of five key publications, or other research outputs (e.g. patents) that best demonstrate previous productivity or a single document giving hyperlinks to these outputs. You must also complete the personal statement section of the application form in the format of a cover letter including the names and contact details of three academic referees Joining as a Group Leader, you will be given outstanding support to help you to continue to develop in your career. Along with a start-up package of funding, you will also have access to resources to establish your group, including support for recruiting key group members, such as PhD students and postdoctoral researchers. We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Professor Emma Hall ([email protected])

Summary of Role We would like to appoint a Senior Trial Manager to be responsible for: • Day to day management of the trial(s) through set-up, recruitment and reporting; • Liaising with stakeholders and participating centres to promote the trial(s) and ensure successful recruitment and delivery; • Co-ordination of data management and biological sample collection activities. The post offers an excellent opportunity for an enthusiastic and well-motivated individual with clinical trial management experience to work in a dynamic and supportive academic environment in a dedicated cancer clinical trials unit. The successful applicant will be responsible for the central coordination of multicentre cancer trials. Key Requirements Applicants should hold a first degree or equivalent level qualification in biological science, social science or other relevant subject (including nursing and health care disciplines) or equivalent, relevant work experience and have a good understanding of the principles of GCP, data protection and research governance. Experience in clinical trial management is essential. We encourage all applicants to access the job pack attached for more detailed information regarding this role. Department/Directorate Information The Institute of Cancer Research is looking for a Senior Trial Manager to join the Cancer Research UK Clinical Trials & Statistics Unit (ICR-CTSU) at its Sutton site in Surrey. ICR-CTSU runs a diverse portfolio of national and international phase III multicentre randomised controlled trials, and phase II trials of targeted treatments with a focus on breast, urological and head and neck cancer treatments. Informal enquiries can be made by emailing [email protected].

About the Role We are seeking a Senior Trusts Fundraising Manager to join our Trusts & Corporate Team and contribute to our income generation plans. The successful candidate will play a key role in maximising income from Trusts and Foundations to support our mission: to make the discoveries that defeat cancer. Key Responsibilities To maximise income from Trusts and Foundations by further developing the ICR’s relationships with existing medium and large Trust donors and by personally securing the support of new ones. You will be required to focus on raising grants broadly in the range of £10k to £500k To develop a donor pipeline aligned with Trusts and Foundations that have a strong synergy with the ICR’s mission and research priorities. The postholder will help shape engagement strategies and secure multi‑year partnerships that deepen the ICR’s institutional relationships About You We are looking for a candidate able to demonstrate a substantial track record of securing support from Trusts and Foundations (including six-figure+ sums) and sustaining a portfolio of partner/donor relationships in the not-for-profit environment. An individual who can develop relationships with individuals at the highest level, both externally and internally, and including with scientists, senior volunteers and trustees. And you must be able to write well, putting together compelling proposals with detailed plans and budgets. What We Offer A supportive and collaborative working environment. Opportunities for professional development and career progression. Competitive salary and pension Department/Directorate Information The Development and Communications directorate tells the ICR’s story and focuses on income generation. The ICR is world-renowned for its outstanding cancer research – and it deserves communication to match. We believe that communicating effectively about the ICR's work can help us build on our successes – attracting donors and supporters, the best staff and students, commercial partners and collaborators. Within the Development and Comms directorate, the Trusts & Corporate team is responsible for all philanthropic organisational relationships for the ICR. We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact the Talent team via Email on [email protected]

Under the guidance of Professor Jyoti Choudhary, we are seeking to appoint a motivated Postdoctoral Training Fellow to develop innovative quantitative proteomics workflows for the characterization of protein degradation and functions. The successful candidate will play a key role in developing or optimising new proteomics methods and undertaking end-to-end analysis of a variety of samples. About you The successful candidate must have: PhD in biochemistry or chemistry with sound knowledge of biological mass spectrometry Expertise in biochemical and protein purification techniques Expertise in computational analysis of omic data-ability to perform statistics, data integration and bioinformatics Candidates who are nearing completion of their PhD may apply, but confirmation on awarded PhD is required within 6 months of employment. The ICR has a workforce agreement stating that Postdoctoral Training Fellows can only be employed for up to 7 years as PDTF at the ICR, providing total postdoctoral experience (including previous employment at this level elsewhere) does not exceed 7 years. For general information on Postdocs at The ICR, more information can be found here. Functional Proteomics Group The Functional Proteomics Group led by Professor Jyoti Choudhary explores the molecular phenotype of cancer studying protein-protein interactions, signalling, post-translational modifications and protein expression. We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Jyoti Choudhary for further information by emailing [email protected].