Clinical trials methodology research at ICR-CTSU
Our applied methodology research portfolio investigates best practice in trial design, conduct, analysis and reporting.
We specialise in applied methodology research which allows exploration and delivery of complex trials applicable in the real-world to benefit people affected by cancer and improve the quality of future oncology research, while also assessing innovative methodology approaches.
Areas of interest
- biomarker-rich trials and trial platforms
- biological endpoints
- technical radiotherapy studies
- imaging biomarkers
- patient reported outcomes
- use of routine data
- equality, diversity and inclusion
- efficient early phase adaptive designs
- integration of omics and clinical data
Key projects and studies
DEFINE
Guidance for Early Phase Dose-Finding trials. This project aims to develop guidance on protocol content and reporting of early-phase trials.REDEFINE
Exploring the Potential Benefits of Decentralisation of Cancer Clinical Trials in the United Kingdom and its Acceptability, Feasibility, Facilitators and Barriers from a Diverse Stakeholder Perspective. This study aims to identify ways to make cancer clinical trials more accessible to everyone, regardless of their circumstances.
