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Newly discovered role for cancer-linked protein exposes vulnerability in tumour cells
Scientists have uncovered a previously hidden role for a protein frequently mutated in cancer, showing that it helps maintain the stability of the genome at some of its most vulnerable sites.
New understanding of enzyme regulating gene expression could inform future cancer therapies
Scientists have uncovered how an important cellular enzyme is regulated, revealing new insights into the fundamental biological processes controlling gene expression and opening up potential avenues for future cancer drug development.
Local anaesthetic shows promise in blocking childhood cancer spread, study finds
A drug best known for numbing the skin before minor medical procedures may hold unexpected promise in tackling one of the most aggressive childhood cancers.
New insights reveal why some triple-negative breast cancers resist treatment
A team co-led by researchers at The Institute of Cancer Research, London, has uncovered how treatment-resistant cancer cells may drive poor outcomes for people with triple-negative breast cancer (TNBC), one of the most aggressive forms of the disease.
Seeing the immune system in action: new imaging study sheds light on cancer immunotherapy
Experts have demonstrated that an innovative, non-invasive imaging technique can be harnessed to monitor oncolytic virotherapy, a rapidly advancing field of cancer treatment.
Excess weight is the strongest clue to the rise in cancer rates in under 50s
Being overweight or obese is an important cause of rising cancer rates among younger adults in England, according to a major new study by researchers from The Institute of Cancer Research, London
New AI tool to assist pathologists in complicated lung cancer analyses
Researchers have developed an artificial intelligence (AI) tool that helps doctors more accurately measure a key marker used to decide which lung cancer patients might benefit from certain treatments.
DNA Day: Why defeating cancer is in our genes
DNA Day marks the anniversary of two important events in the history of genetics – the publication of the discovery of the DNA double helix in 1953, and the completion of the Human Genome Project in 2003.
-16-9.jpg?sfvrsn=b9495114_2 "Glioblastoma cells (Dr Chris Jones/the ICR) 16:9")
ICR plays key role in groundbreaking new brain cancer trials
Scientists from The Institute of Cancer Research (ICR), London, are taking part in a groundbreaking new set of brain cancer clinical trials designed to improve survival and quality of life for people with glioblastoma.
-growing-in-single-files-along-collagen-fibres-(red)_renee-flaherty.jpg?sfvrsn=b3bf3bc8_3 "Invasive lobular breast cells (yellow) growing in single files along collagen fibres (red)_Renee Flaherty")
Scientists identify a potential new treatment option for lobular breast cancer
A drug currently being tested in clinical trials for a rare blood cancer could also be used to treat lobular breast cancer, according to a study published in the journal Cancer Research.
Scientists develop new way to determine which patients will respond best to bowel cancer treatment
Scientists have developed an AI-powered method that could determine which patients with advanced bowel cancer are most likely to respond to a targeted drug used on the NHS – potentially sparing thousands of patients from treatments that won’t work for them.
UK scientists create most detailed map yet of mutations that drive cancer
Scientists have created the most comprehensive map to date of the genetic mutations that fuel cancer – opening the door to extending precision treatments to thousands more patients and offering clues as to why bowel cancer rates are rising in younger people.
