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Clinical PhD Fellowships

Our clinical PhD fellowships are provided to develop and support future leaders in clinical cancer research.

About our clinical PhD fellowships

Our clinical PhD fellowships are provided to develop and support future leaders in clinical cancer research. The Clinical Academic Training Programme, ICR-Imperial is a programme which will provide clinical academics with the expertise to discover, develop, and deliver the next generation of treatments, technologies, and methodologies into clinical care.

The fellowship awards include tuition fees, research expenses, and a clinical salary. Applicants from a range of clinical specialities are invited to apply, including oncology, paediatrics, radiology, surgery, anaesthesia, and haematology.

Current opportunities

We are advertising a range of projects. You can read the project proposals below, and follow the links for more information. If the opportunities below don't interest you, you can sign up to our mailing list for future opportunities.

 

Available projects and the project archive

You can view our current and past projects, below. Use the dropdowns to select the subject you are interested in, and then click 'Filter' to see relevant projects. If you use a filter and cannot see any results, then there are no projects matching your requirements.

Clinical specialty:

Primary institution:

Deadline:

 

Novel liquid biopsies to guide treatment in recurrent head and neck cancer

  • Primary Supervisor: Dr Ben O'Leary (ICR)
  • Primary Division: Division of Radiotherapy & Imaging
  • Primary Team: Targeted Therapy

Project summary

Intelligent adaptive radiotherapy for pelvic malignancies

  • Primary Supervisor: Dr Susan Lalondrelle (ICR)
  • Primary Division: Division of Radiotherapy & Imaging
  • Primary Team: Gynaecological Cancer

Project summary

Exploration of the combination of oncolytic virus and PARP inhibition in triple-negative breast cancer and the effect on the immune microenvironment

  • Primary Supervisor: Prof Kevin Harrington (ICR)
  • Primary Division: Division of Radiotherapy & Imaging
  • Primary Team: Targeted Therapy Team

Project summary

Assessing personalised brain tumour evolution dynamics with synthetic DTI, MR radiomics and near-patient sensing

  • Primary Supervisor: Dr Matt Williams (Imperial)
  • Primary Division: Division of Cancer
  • Primary Team: Surgery & Cancer

Project summary

Investigating drug resistance and sensitivity of emerging therapies in KRAS G12C mutated colon cancers

  • Primary Supervisor: Prof Udai Banerji (ICR)
  • Primary Division: Division of Clinical Studies
  • Primary Team: Clinical Pharmacology & Adaptive Therapy

Project summary

Enhancing the precision of lung cancer immunotherapy: development of new AI driven biomarkers of resistance utilising samples from the phase III REFINE-Lung study

  • Primary Supervisor: Dr Ehsan Ghorani (Imperial)
  • Primary Division: Division of Medicine
  • Primary Team: Surgery & Cancer

Project summary

Image based grading of liquid biopsies

  • Primary Supervisor: Dr Ali Salehi-Reyhani (Imperial)
  • Primary Division: Division of Cancer
  • Primary Team: Surgery & Cancer

Project summary

An artificial intelligence-based approach to identify immunologic predictors of outcome to immunotherapy in hepatocellular cancer using digital pathology

  • Primary Supervisor: Dr David James Pinato (Imperial)
  • Primary Division: Division of Cancer
  • Primary Team: Developmental Therapeutics

Project summary

Retrospective Clinical Validation of Radiotherapy Recurrence and Treatment Predictive Biomarkers in Muscle-invasive Bladder Cancers using Large Clinical Trial Samples

  • Primary Supervisor: Prof Anguraj Sadanandam (ICR)
  • Primary Division: Division of Molecular Pathology
  • Primary Team: Systems & Precision Cancer Medicine

Project summary

Development of cancer triage pathways and multi-centre evaluation of Rapid Diagnostic centres

  • Primary Supervisor: Prof Ceire Costelloe (ICR)
  • Primary Division: Division of Clinical Studies
  • Primary Team: Health Informatics

Project summary

Validation of multiplex assays of variant effect (MAVES) in cancer susceptibility genes

  • Primary Supervisor: Prof Clare Turnbull (ICR)
  • Primary Division: Division of Genetics & Epidemiology
  • Primary Team: Translational Genetics

Project summary

Developing transcription inhibitors as a new class of cancer therapeutics

  • Primary Supervisor: Prof Simak Ali (Imperial)
  • Primary Division: Division of Cancer
  • Primary Team: Department of Surgey & Cancer

Project summary

Previous projects 

Identification of novel tissue and circulating biomarkers of anti-tumoral immune response and identification of novel drug targets in locally-advanced head and neck squamous cell carcinoma (LA-HNSCC)
Shreerang Bhide (ICR)

Decreasing the burden of cancer (early detection in high risk groups with a genetic predisposition and identification of new methods of screening)
Ros Eeles (ICR)

ctDNA guided optimisation of chemotherapy in colorectal cancer using evolutionary genomics
Trevor Graham (ICR)

Lung cancer early detection: novel liquid biopsy technologies with a metabolomics focus
Richard Lee (ICR)

Bone marrow microenvironment remodelling and innate immunity signalling pathways in acute myeloid leukaemia patient responses
Cristina Lo Celso (Imperial)

Molecular and imaging biomarkers for prostate cancer
Stephen Mangar (Imperial)

Super-resolution imaging to assess epigenetic evolution in ovarian high grade serous carcinoma
Iain McNeish (Imperial)

Investigating and targeting the sub-clonal dynamics of therapy resistance in metastatic invasive lobular breast cancer
Rachael Natrajan (ICR)

Drivers of metastasis and recurrence in head and neck and gynaecological squamous cell carcinomas
Ben O'Leary (ICR)

Development of a disruptive artificial intelligence-based multi-modal companion diagnosis for precise combination cancer immunotherapies
Anguraj Sadanandam (ICR)

Improving patient outcomes by circumventing treatment resistance in lethal prostate cancer
Adam Sharp (ICR)

The development of novel fluorescence and radiolabelled markers in gastrointestinal stromal tumour (GIST) and evaluation of their use perioperative assessment and fluorescence guided surgery
Myles Smith (ICR)

Harnessing the immunogenic potential of radiotherapy for maximum impact in high-risk hormone positive breast cancer patients – translational research linked to neo-adjuvant radiotherapy trials
Navita Somaiah (ICR)

Incorporating uncertainty information into artificial intelligence auto-contouring approaches for radiotherapy planning
Alexandra Taylor (ICR)

Developing a miniaturised robotics platform with integrated real-time metabolomics for first-in-human enhanced minimally invasive surgery in head and neck cancer
Burak Temelkuran (Imperial)

Analysing gene expression changes with liquid biopsies to identify mechanisms of resistance to breast cancer treatment
Nicholas Turner (ICR)

Using argumentation-based eXplainable AI to integrate large, shallow and small detailed datasets in palliative radiotherapy
Matt Williams (Imperial)

Discovering novel immunogenic peptides induced by aberrant splicing in breast cancer
Luis Zapata (ICR)

Predictors of lung cancer response to immunotherapy
William Cookson (Imperial)

Targeting inflammatory cell mediated fuelling of prostate cancer
Johann de Bono (ICR)

T-cell phenotypes and dynamics in gastro-oesophageal cancer immunotherapy
Marco Gerlinger (ICR)

Developing integrative biomarkers for improving neoadjuvant therapy in high-risk soft tissue sarcoma
Paul Huang (ICR)

Immunoengineering strategies for biomimetic silicone implant design to mitigate the risk of radiotherapy-induced capsular contracture in implant-based breast reconstruction
Aadil Khan (ICR/RMH)

Understanding Role of Tumour Heterogeneity and Evolution in treatment resistance in Aggressive Thyroid Cancers: utility of circulating free tumour DNA (ctDNA)
Dae Kim (ICR/RMH)

Neuroendocrine markers in colorectal adenocarcinomas
Christos Kontovounisios (Imperial)

Investigation of Immune and Microbiome Disruption as drivers of mutagenic pathways in Oesophago-Gastric Cancer
Sacheen Kumar (ICR)

Management of cancer risk in people with Lynch Syndrome and a Family History of Colorectal Cancer (CRC)
Kevin Monahan (Imperial)

Radiogenomics and hepatocellular cancer
Rohini Sharma (Imperial)

Determinants of toxicity in prostate radiotherapy
Alison Tree (ICR/RMH)

Deciphering cancer evolution through post-mortem profiling
Samra Turajlic (ICR/RMH/Crick)

Massive germline exome sequencing to identify novel breast cancer susceptibility genes
Clare Turnbull (ICR)

Predicting and targeting neoantigens associated with BRCA1/2 reversion mutations in PARP inhibitor and platinum-resistant breast cancer
Andrew Tutt (ICR)

Mechanistic exploration of cell-free tumour DNA (ctDNA) shedding into circulation using microfluidic vascularised organoid-on-chip models
Nicola Valeri (Imperial)