Dr Alex Radzisheuskaya is a Team Leader in the Division of Cancer Biology at the Institute of Cancer Research, London. She started at the ICR in November 2021.
Alex is originally from Belarus. In 2008, she received the Darwin Trust of Edinburgh Scholarship to pursue her studies at the University of Edinburgh, where she received her BSc with Honours in Molecular Biology. In 2014, she earned her PhD from the University of Cambridge, where she studied mechanisms of induced pluripotency at the laboratory of Dr Jose CR Silva at the Wellcome Trust – MRC Cambridge Stem Cell Institute.
For her postdoctoral research, Dr Radzisheuskaya joined the laboratory of Professor Kristian Helin at the Biotech Research and Innovation Center in Copenhagen. The overall theme of her postdoctoral work was understanding how chromatin-associated proteins regulate gene expression and cell fate decisions and how they contribute to cancer, in particular acute myeloid leukaemia.
For this work, she secured two postdoctoral fellowships: Marie Skłodowska-Curie Individual Postdoc Fellowship and EMBO Long-Term Postdoc Fellowship. In 2018, the laboratory moved to Memorial Sloan Kettering Cancer Center in New York, where she continued her research until November 2021.
The major focus of Alex’s laboratory at the ICR is to understand how post-translational modifications on histone proteins regulate genome organization and stability and how they contribute to the development of cancer.