Professor Vlad Pena's team focuses on the structural basis of human pre-mRNA processing under normal, pathological and drug-induced conditions.
Professor Vlad Pena uses biochemistry, electron cryo-microscopy and X-ray crystallography to understand splicing regulation and the connections between splicing and other gene expression processes. He is a Professor of Structural Biology and Gene Expression at the ICR.
I joined the ICR in 2019. My PhD project is focused on investigating important functional links between splicing and other fundamental events in the cell at the molecular level using biochemical tools and Cryo-EM.
I have a keen interest in structural biology and in particular in Cryo-Electron Microscopy (Cryo-EM). The focus of my PhD is to decipher the mechanism of action of complex ribonucleoprotein assemblies using single particle Cryo-EM.
I am a PhD student in the Division of Structural Biology and my aim is to get a better understanding of pre-mRNA splicing regulation through Cryo-EM analysis.
I am a PhD student and I’m interested in understanding the functions and structure of the splicing molecular machinery and capture its linking to other close related events in gene expression.