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Translational Therapeutics

Dr Adam Sharps' Team searches for novel therapeutic strategies to prevent the development of treatment resistance and to overcome the progression of cancer.

Team leader

Dr Adam Sharp

Dr Adam Sharp

Dr Adam Sharp is Leader of the Translational Therapeutics Team and Honorary Consultant Medical Oncologist within the Prostate Cancer Targeted Therapies Group and Drug Development Unit at the ICR and The Royal Marsden NHS Foundation Trust.

ORCID 0000-0002-3740-1612

Team members

Denisa Bogdan
Denisa Bogdan
Bioinfomatician +44 20 3437 6096

I am a bioinformatician working in the Cancer Biomarkers and Translational Therapeutics Teams at the Institute of Cancer Research. I work with next generation sequencing data to understand prostate cancer biomarkers in advanced disease. I have a multidisciplinary background in medicinal chemistry and molecular biology, as well as bioinformatics expertise, particularly in transcriptomics, epigenomics, integrative omics and biostatistics.

Dr Juan Jimenez Vacas
Dr Juan Jimenez Vacas
Postdoctoral Training Fellow +44 20 3437 6230

I am a Prostate Cancer UK Postdoctoral Travelling Fellow working in the Cancer Biomarkers and Translational Therapeutics teams at Institute of Cancer Research. I am currently focused on developing novel therapeutic strategies, as well as discovering vulnerabilities of advanced prostate cancer, to prevent the development of resistance against drugs currently used in clinical practise to tackle this disease.

Dr Ana Prim Padilha
Dr Ana Prim Padilha
Higher Scientific Officer +44 20 3437 6560

I am a Higher Scientific Officer working in the Translational Therapeutics Team at the Institute of Cancer Research. I am supporting the team in various projects with the aim to learn more about prostate cancer biology and to develop novel therapeutic strategies to treat patients with advanced disease.

Joe Taylor
Joe Taylor
Postdoctoral Training Fellow +44 20 3437 6844

I am a Postdoctoral Training Fellow working in the Translational Therapeutics team at the Institute of Cancer Research. My research is focused on the role of mRNA translation in prostate cancer, with a focus on discovering novel therapeutic vulnerabilities of advanced stage disease and to identify resistance mechanisms for drugs that are used in the clinic.

Dr Daniel Westaby
Dr Daniel Westaby
Clinical Training Fellow +44 20 3437 6519

I am a CRUK Clinical Research Training Fellow working in the Translational Therapeutics Team and the Prostate Cancer Targeted Therapies Group at the Institute of Cancer Research and Royal Marsden Hospital. I have an interest in developing novel therapeutic approaches to improve outcomes for men with advanced prostate cancer. My PhD is focused on the pre-clinical development and translation of strategies to target the intrinsic apoptosis pathway.

Wanting Zeng
Wanting Zeng
Scientific Officer +44 20 3437 6802

I am a Scientific Officer and I work closely with all members of the team to provide technical support whilst expanding my own research skills in cancer research. I am working on a number of projects in which the team are trying to develop and deliver new therapeutic strategies for patients with prostate cancer. I hope to support the team in translating these pre-clinical findings to the clinic, and help improve the outcome for men with advanced prostate cancer.

Dr Souvik Das
Higher Scientific Officer T +44 20 3437 6831
Natalie Lewis
Personal Assistant T +44 20 3437 6522