ICR-CTSU Breast and Rare Cancers Trials Group
Professor Judith Bliss’s group within the ICR’s Clinical Trials and Statistics Unit carries out clinical trials for the treatment of early and late-stage breast cancer and melanomas.
Research, projects and publications in this group
Our research aims to develop, conduct and report high quality trials, and associated research, of scientific importance and which will impact directly on clinical practice of breast and rare cancers within the NHS and internationally.
Professor Judith Bliss
Professor of Clinical Trials, Group Leader:
ICR-CTSU Breast and Rare Cancers Trials
Professor Judith Bliss is the Director of the Cancer Research UK funded Clinical Trials & Statistics Unit (ICR-CTSU) and Deputy Head of the Division of Clinical Studies. Professor Bliss is investigating how best to personalise breast and rare cancer treatment for individual patients. She is a member of several national and international research groups, and is Chair of the UK Breast Intergroup.
Researchers in this group
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Professor Judith Bliss's group have written 275 publications
Most recent new publication 6/2025
See all their publicationsThe Cancer Research UK funded Clinical Trials and Statistics Unit (ICR-CTSU) provides the scientific leadership and operational management to develop, conduct and report high quality, innovative randomised trials, with integrated translational and psychosocial research. ICR-CTSU is an NCRI Accredited and UKCRC Registered Clinical Trials Unit with an established track record. Recently published trials have led directly to changes in clinical practice. Our research work is focussed in selected clinical and therapeutic areas; with Professor Bliss leading the ICR-CTSU Breast and Rare Cancers Trials Group undertaking trials of systemic therapies, radiotherapy and surgical techniques.
The aims of the research are to continue to develop, conduct and report high quality trials, and associated research, of scientific importance and which will impact directly on clinical practice within the NHS and internationally. Building on past successes, and recognising the changing national and international priorities for clinical trials, our programme of randomised trials have the following focus:
Early breast cancer – systemic therapy
- The advent of UK based peri-operative trials
- International trials for targeted treatments – what can the UK offer?
- Refining adjuvant chemotherapy – where do we go next?
Advanced breast cancer – systemic therapy
- Development of targeted therapies
Early breast cancer – radiotherapy
- The limits of hypofractionation
- Tailoring radiotherapy
Surgical trials and other cancer sites
- Complex surgical interventions
- Head and neck cancer
Fundamental to both the scientific hypothesis, and to the conduct of these trials, is the targeting of treatments towards patients with the most potential for therapeutic gain. In addition to evaluation of therapeutic outcome, scientific output will be maximised by integrated biomarker directed translational research; patient assessed quality of life & symptom evaluation; statistical and trials methodology research.