Guidelines should change so that all men over the age of 40 with faults in the BRCA2 gene should be offered regular PSA testing to detect early signs of prostate cancer, experts are urging.

Men with faults in the BRCA2 gene have an increased risk of prostate cancer and could benefit from PSA testing to help detect the disease earlier, according to new research.

A new panel of genes could pick out men at highest risk of developing prostate cancer and pick out those already diagnosed who are likely to have particularly aggressive forms of the disease, a large-scale genetic analysis has found.