People in the UK will for the first time have their entire genetic code read from samples taken at a GP practice as part of a pioneering study to assess the potential benefits of screening for gene faults that increase the risk of disease.

Guidelines should change so that all men over the age of 40 with faults in the BRCA2 gene should be offered regular PSA testing to detect early signs of prostate cancer, experts are urging.

Men with faults in the BRCA2 gene have an increased risk of prostate cancer and could benefit from PSA testing to help detect the disease earlier, according to new research.