Patient stories

Elen Hughes was first diagnosed with primary invasive lobular breast cancer in 2008 at the age of 37. Eight years later, her cancer returned and spread, and she has been on a rollercoaster journey ever since, experiencing the highs of remission and the lows of numerous relapses. Since February 2025, she has been treated with the drug capivasertib, the discovery of which was underpinned by research at The Institute of Cancer Research. She is now doing well and feels hopeful for her future.

Sophie Norman had just turned 16 when she was diagnosed with the blood cancer acute lymphoblastic leukaemia (ALL) in the summer of 2021. Now aged 19 and cancer free, she is in her first year at Bath University, studying Biochemistry. She is looking forward to a career in medical research, inspired by the scientists she met at The Institute of Cancer Research (ICR) during a work experience placement in our Centre for Cancer Drug Discovery.

Karen Mawdsley’s daughter, Ellie, was diagnosed with DIPG (diffuse intrinsic pontine glioma), an aggressive brain tumour, in December 2021. She sadly passed away in July 2023, aged 23. Ellie was determined to improve the lives of young people with brain cancer and selflessly donated her brain tissue to The Institute of Cancer Research. Her parents, Karen and Ian, are continuing her legacy and have set up The Ellie Mawdsley Foundation to raise awareness and fund further vital research into brain tumours in Ellie’s memory.

Markus was shocked when he was diagnosed with the blood cancer chronic lymphocytic leukaemia (CLL) in 2021. Determined to break down barriers and start conversations about cancer, Markus turned to art as a way of sharing his experiences.

When personal trainer Gemma Seager, 45, injured her back while lifting weights, she assumed it would improve with rest. But after 10 months of pain, she was diagnosed with myeloma, a type of blood cancer, in June 2021. Thanks to treatment, she currently has no evidence of disease in her body and recently completed the London Marathon.

In April 2019, Claire Shepherd, now 34, began feeling unwell and constantly fatigued. Having initially put her symptoms down to her hectic lifestyle, she was shocked to be diagnosed with acute myeloid leukaemia (AML). Now, six years on and following successful treatment, she is in remission and making the most of every day…

Cecelia Brunott, 48, was diagnosed with myeloma in 2020. She had a stem cell transplant and is currently taking a targeted treatment to keep her cancer stable. She lives in Farnham, Surrey, with her wife Eva.

Karin Manchester, 65, was told she had a week to live after being diagnosed with acute myeloid leukaemia (AML), a type of blood cancer, in 2004. Thanks to successful treatment and taking part in a clinical trial, she has been in remission for over 20 years.