Genomics

Advances in the technology to read people’s DNA have made it so much faster and cheaper that we can now read the genetic code of many different genes at once, increasingly by sequencing the entire genome of a patient or their cancer.

Comparing a genome sequence from a tumour cell with one from a healthy cell allows our researchers to pinpoint the genetic changes that are involved in causing cancer, helping us to create new and improved treatments. We can also learn about genetic changes people inherit which may increase their risk of cancer, and this can lead to new ways of preventing the disease.

This page highlights recent news stories, blog posts and videos that concern the use of genomics technologies in cancer research.

Recent stories on genomics technologies in cancer research

Maggie Cheang pictured smiling.
ICR researcher awarded prestigious lectureship for practice-changing breast cancer research

23/06/25

Dr Maggie Cheang, a breast cancer researcher at The Institute of Cancer Research, London, has been awarded the prestigious CL Oakley lectureship.
Multiple trays of small, transparent containers or vials filled with liquids
Scientists find new way to predict how bowel cancer drugs will stop working

20/06/25

Scientists from The Institute of Cancer Research, London, have developed a tool that can predict how bowel cancer adapts to treatment – helping researchers to design new personalised drugs that will keep patients living well for longer.
An image of bowel tumour organoids on a black background
Scientists uncover clues behind drug resistance in bowel cancer

16/06/25

Scientists have discovered clues which may explain why some treatments stop working for people with bowel cancer – causing around 16,800 deaths in the UK every year. The study, led by researchers at The Institute of Cancer Research, London, could help clinicians make better use of current treatments and develop more targeted therapies for bowel cancer in the future.
Cell Division-(green-4-3)945x532
New protective role of gene frequently mutated in cancer uncovers potential therapeutic target

02/05/25

New research into how cancer develops has uncovered more detail about the importance of the centromere, a region of human DNA that has a critical role in effective cell division.
Intermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour
Smarter chemotherapy approach could delay drug resistance in ovarian cancer

01/05/25

Adaptive chemotherapy – a personalised approach to giving chemotherapy – can prolong survival in lab models of ovarian cancer, according to new results published in the journal Cancer Research.
Genetic study links common form of testicular cancer to rare variants in cell structure genes

24/04/25

The largest study to date of most common form of testicular cancer has uncovered a possible link between disease risk and variations in the genes controlling cell shape and movement.
ICR scientists unveil AI-powered platform that helps researchers speed up biomarker discoveries for personalised cancer treatment

02/04/25

An ICR team has unveiled a cutting-edge research platform powered by artificial intelligence (AI) that will revolutionise cancer research by allowing researchers to integrate and analyse large and complex clinical trial datasets, speeding up the discovery of new cancer biomarkers.
Mini tumours grown from a bowel cancer
£5.5m research funding to transform bowel cancer care

30/03/25

Scientists from The Institute of Cancer Research, London, are part of a team of international researchers who have secured £5.5million in funding to find smarter, kinder treatments for people living with bowel cancer.