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Sarcoma Molecular Pathology Team

Professor Janet Shipley’s team is investigating ways to improve the treatment of patients with soft tissue sarcomas associated with poor clinical outcome.

Group leader

Professor Janet Shipley

Professor Janet Shipley

Professor Janet Shipley is investigating ways to improve the treatment of patients with sarcomas that have a poor outcome.

ORCID 0000-0001-6748-8678

Group members

Dr Ewa Aladowicz
Dr Ewa Aladowicz
Senior Scientific Officer +44 20 8722 4181

I joined the ICR in 2013. I work on the development and characterisation of 3D and PDX models of paediatric sarcomas. I use these models to study new therapies that combine standard chemotherapy with targeting drugs.

Dr Carolina Bernauer
Dr Carolina Bernauer
PhD Student +44 20 8722 4181

I am a Clinical Research Fellow interested in understanding the complexities of cancer and bridging the gap between researchers and clinicians. My current project is focused on understanding whether tumour hypoxia can be targeted, and used as a predictive biomarker to improve treatment response, in patients with aggressive forms of rhabdomyosarcoma.

Dr Anastasia Loktev
Dr Anastasia Loktev
Honorary Appointment +44 20 8722 4221

My research interests lie within translational cancer research to develop better therapeutic interventions for patients. Currently, I am working on combination treatments for the targeted therapy of rare paediatric sarcomas.

Dr Stella Man
Dr Stella Man
Higher Scientific Officer

I am currently developing three dimensional spheroid models for paediatric soft tissue sarcomas. The in vitro models will serve as invaluable tools for testing novel treatment strategies as well as for understanding the role of the tumour stroma on these rare and often aggressive tumours.

Dr Antonio Romo Morales
Dr Antonio Romo Morales
Honorary Appointment

I’m in the final year of my PhD in Ewing Sarcoma. My research aim is to identify novel therapeutic strategies for this rare cancer through combination strategies using spheroid models and molecular biology techniques.

Dr Olivia Ruhen
Dr Olivia Ruhen
Honorary Appointment

I work on rhabdomyosarcoma, an aggressive cancer of the soft tissue which is most common in children and young adults. My project is focused on developing a new circulating tumour DNA-based blood test which will hopefully enable earlier detection of treatment failure and disease recurrence in paediatric rhabdomyosarcoma patients.

Dr Joanna Selfe
Dr Joanna Selfe
Senior Scientific Officer

I am a Senior Scientific Officer and am involved in several projects looking at rhabdomyosarcoma. These involve trying to improve the prognostication of rhabdomyosarcoma as well as identifying new drug targets and approaches to treating rhabdomyosarcoma to achieve better outcomes while sparing children unnecessary treatment and therefore side effects that can affect them in later life.

Brenda Summersgill
Brenda Summersgill
Volunteer

I joined the team in 1992 working mainly with rhabdomyosarcoma and testicular germ cell tumours. Since 2014 I have worked on a voluntary basis cataloguing the department's tissue assets.

Dr Kallayanee Chawengsaksophak
Senior Staff Scientist T +44 20 3437 6281
Dr Susanne Gatz
Honorary Appointment
Dr Supriti Ghosh
Postdoctoral Training Fellow T +44 20 3437 6839
Yeman Hagos
Honorary Appointment
Dr Lisa Thompson
Honorary Appointment
Professor Nicola Valeri
Honorary Appointment T +44 20 8722 4311
Professor Yinyin Yuan
Honorary Appointment