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ICR-CTSU clinical trials

The ICR-CTSU manages a number of trials in different disease sites. Use the filter below to view trials for each cancer type:

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Open to recruitment

PACE

International randomised study of laparoscopic prostatectomy vs stereotactic body radiotherapy (SBRT) and conventional radiotherapy vs SBRT for early stage organ-confined prostate cancer.

RE-AKT

Randomised phase II study of enzalutamide (MDV3100) in combination with AZD5363 in patients with metastatic castration resistant prostate cancer.

In follow-up

CHHiP

Conventional or hypofractionated high dose intensity modulated radiotherapy for prostate cancer.

CORE

Conventional care versus Radioablation (stereotactic body radiotherapy) for extracranial oligometastases.

CTC-STOP

Utilising Circulating Tumour Cell (CTC) counts to optimize systemic therapy of metastatic prostate cancer.

LopeRA

Randomised controlled trial of laparoscopic, open and robot assisted prostatectomy as treatment for organ confined prostate cancer.

PIVOTAL

Randomised phase II trial of prostate and pelvis versus prostate alone treatment for locally advanced prostate cancer.

PROMPTS

Prospective randomised phase III study of observation versus screening MRI and pre-emptive treatment in castrate resistant prostate cancer patients with spinal metastasis.

REASURE

Phase II open label study of biomarkers to assess response in patients with metastatic castration-resistant prostate cancer treated with radium-223.

Closed

Intercontinental

Intercontinental is an international phase III randomised trial comparing intermittent versus continuous androgen suppression for patients with prostate-specific-antigen progression in the clinical absence of distant metastases following radiotherapy for prostate cancer.

ProSTART

A Pilot Study for a Phase III Clinical Trial in Patients with Favourable Risk Prostate Cancer Comparing Active Surveillance Therapy Against Radical Treatment

TOPARP

Phase II trial of olaparib in patients with advanced castration resistant prostate cancer.

Division of Clinical Studies

The division carries out or coordinates high-quality trials and translational research at both an early phase – typically to test new targeted drugs – and a later stage.

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