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Journal Articles

Moerke, C., Jaco, I., Dewitz, C., Müller, T., Jacobsen, A.V., Gautheron, J., Fritsch, J., Schmitz, J., Bräsen, J.H., Günther, C., et al. (2019). The anticonvulsive Phenhydan® suppresses extrinsic cell death. Cell death & differentiation, Vol.26 (9), pp. 1631-1645.

Legrand, A.J., Konstantinou, M., Goode, E.F. & Meier, P. (2019). The Diversification of Cell Death and Immunity: Memento Mori. Molecular cell, .

Annibaldi, A. & Meier, P. (2018). Checkpoints in TNF-Induced Cell Death: Implications in Inflammation and Cancer. Trends in molecular medicine, Vol.24 (1), pp. 49-65.

Barry, R., John, S.W., Liccardi, G., Tenev, T., Jaco, I., Chen, C.-., Choi, J., Kasperkiewicz, P., Fernandes-Alnemri, T., Alnemri, E., et al. (2018). SUMO-mediated regulation of NLRP3 modulates inflammasome activity. Nat commun, Vol.9 (1), p. 3001.  show abstract

Galluzzi, L., Vitale, I., Aaronson, S.A., Abrams, J.M., Adam, D., Agostinis, P., Alnemri, E.S., Altucci, L., Amelio, I., Andrews, D.W., et al. (2018). Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell death & differentiation, Vol.25 (3), pp. 486-541.

Salla, M., Aguayo-Ortiz, R., Danmaliki, G.I., Zare, A., Said, A., Moore, J., Pandya, V., Manaloor, R., Fong, S., Blankstein, A.R., et al. (2018). Identification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity Analysis. Journal of pharmacology and experimental therapeutics, Vol.365 (2), pp. 354-367.

Annibaldi, A. & Meier, P. (2018). Ripk1 and haematopoiesis: a case for LUBAC and Ripk3. Cell death differ, Vol.25 (8), pp. 1361-1363.

Jaco, I., Annibaldi, A., Lalaoui, N., Wilson, R., Tenev, T., Laurien, L., Kim, C., Jamal, K., Wicky John, S., Liccardi, G., et al. (2017). MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death. Mol cell, Vol.66 (5), pp. 698-710.e5.  show abstract

Horn, S., Hughes, M.A., Schilling, R., Sticht, C., Tenev, T., Ploesser, M., Meier, P., Sprick, M.R., MacFarlane, M. & Leverkus, M., et al. (2017). Caspase-10 Negatively Regulates Caspase-8-Mediated Cell Death, Switching the Response to CD95L in Favor of NF-κB Activation and Cell Survival. Cell rep, Vol.19 (4), pp. 785-797.  show abstract

Wallberg, F., Tenev, T. & Meier, P. (2016). Time-Lapse Imaging of Cell Death. Cold spring harbor protocols, Vol.2016 (3), pp. pdb.prot087395-pdb.prot087395.

Meier, P. & Banreti, A. (2016). Tissue Repair: How to Inflame Your Neighbours. Current biology, Vol.26 (5), pp. R192-R194.

Orme, M.H., Liccardi, G., Moderau, N., Feltham, R., Wicky-John, S., Tenev, T., Aram, L., Wilson, R., Bianchi, K., Morris, O., et al. (2016). The unconventional myosin CRINKLED and its mammalian orthologue MYO7A regulate caspases in their signalling roles. Nature communications, Vol.7 (1).

Plaza-Menacho, I., Barnouin, K., Barry, R., Borg, A., Orme, M., Chauhan, R., Mouilleron, S., Martínez-Torres, R.J., Meier, P. & McDonald, N.Q., et al. (2016). RET Functions as a Dual-Specificity Kinase that Requires Allosteric Inputs from Juxtamembrane Elements. Cell reports, Vol.17 (12), pp. 3319-3332.

Morris, O., Liu, X., Domingues, C., Runchel, C., Chai, A., Basith, S., Tenev, T., Chen, H., Choi, S., Pennetta, G., et al. (2016). Signal Integration by the IκB Protein Pickle Shapes Drosophila Innate Host Defense. Cell host microbe, Vol.20 (3), pp. 283-295.  show abstract

Neyen, C., Runchel, C., Schüpfer, F., Meier, P. & Lemaitre, B. (2016). The regulatory isoform rPGRP-LC induces immune resolution via endosomal degradation of receptors. Nature immunology, Vol.17 (10), pp. 1150-1158.

Galluzzi, L., Bravo-San Pedro, J.M., Vitale, I., Aaronson, S.A., Abrams, J.M., Adam, D., Alnemri, E.S., Altucci, L., Andrews, D., Annicchiarico-Petruzzelli, M., et al. (2015). Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell death & differentiation, Vol.22 (1), pp. 58-73.

Meier, P., Morris, O. & Broemer, M. (2015). Ubiquitin-Mediated Regulation of Cell Death, Inflammation, and Defense of Homeostasis. , , pp. 209-239.

Silke, J. & Meier, P. (2013). Inhibitor of Apoptosis (IAP) Proteins-Modulators of Cell Death and Inflammation. Cold spring harbor perspectives in biology, Vol.5 (2).

Borst, G.R., McLaughlin, M., Kyula, J.N., Neijenhuis, S., Khan, A., Good, J., Zaidi, S., Powell, N.G., Meier, P., Collins, I., et al. (2013). Targeted Radiosensitization by the Chk1 Inhibitor SAR-020106. International journal of radiation oncology biology physics, Vol.85 (4), pp. 1110-1118.

Meier, P. (2012). Ubiquitin-mediated regulation of RhoGTPase signalling: IAPs and HACE1 enter the fray. Embo journal, Vol.31, pp. 1-2.  show abstract

Meinander, A., Runchel, C., Tenev, T., Chen, L., Kim, C.-., Ribeiro, P.S., Broemer, M., Leulier, F., Zvelebil, M., Silverman, N., et al. (2012). Ubiquitylation of the initiator caspase DREDD is required for innate immune signalling. Embo j, Vol.31 (12), pp. 2770-2783.  show abstract

Lopez, J., John, S.W., Tenev, T., Rautureau, G.J., Hinds, M.G., Francalanci, F., Wilson, R., Broemer, M., Santoro, M.M., Day, C.L., et al. (2011). CARD-Mediated Autoinhibition of cIAP1's E3 Ligase Activity Suppresses Cell Proliferation and Migration. Mol cell, .  show abstract

Tenev, T., Bianchi, K., Darding, M., Broemer, M., Langlais, C., Wallberg, F., Zachariou, A., Lopez, J., Macfarlane, M., Cain, K., et al. (2011). The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs. Mol cell, .  show abstract

Lee, T.V., Fan, Y., Wang, S.A., Srivastava, M., Broemer, M., Meier, P. & Bergmann, A. (2011). Drosophila IAP1-Mediated Ubiquitylation Controls Activation of the Initiator Caspase DRONC Independent of Protein Degradation. Plos genet, Vol.7 (9),  show abstract

Darding, M., Feltham, R., Tenev, T., Bianchi, K., Benetatos, C., Silke, J. & Meier, P. (2011). Molecular determinants of Smac mimetic induced degradation of cIAP1 and cIAP2. Cell death differ, .  show abstract

Darding, M. & Meier, P. (2011). IAPs: Guardians of RIPK1. Cell death differ, .  show abstract

Tenev, T., Bianchi, K., Darding, M., Broemer, M., Langlais, C., Wallberg, F., Zachariou, A., Lopez, J., MacFarlane, M., Cain, K., et al. (2011). The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs (vol 43, pg 432, 2011). Mol cell, Vol.43 (4), pp. 689-689.

Gyrd-Hansen, M. & Meier, P. (2010). IAPs: from caspase inhibitors to modulators of NF-kappa B, inflammation and cancer. Nat rev cancer, Vol.10 (8), pp. 561-574.  show abstract

Broemer, M., Tenev, T., Rigbolt, K.T., Hempel, S., Blagoev, B., Silke, J., Ditzel, M. & Meier, P. (2010). Systematic in vivo RNAi analysis identifies IAPs as NEDD8-E3 ligases. Mol cell, Vol.40 (5), pp. 810-822.  show abstract

Lopez, J. & Meier, P. (2010). To fight or die - inhibitor of apoptosis proteins at the crossroad of innate immunity and death. Curr opin cell biol, Vol.22 (6), pp. 872-881.  show abstract

Paquette, N., Broemer, M., Aggarwal, K., Chen, L., Husson, M., Erturk-Hasdemir, D., Reichhart, J.M., Meier, P. & Silverman, N. (2010). Caspase-Mediated Cleavage, IAP Binding, and Ubiquitination: Linking Three Mechanisms Crucial for Drosophila NF-kappa B Signaling. Mol cell, Vol.37 (2), pp. 172-182.  show abstract

Broemer, M. & Meier, P. (2009). Ubiquitin-mediated regulation of apoptosis. Trends cell biol, Vol.19 (3), pp. 130-140.  show abstract

Orme, M. & Meier, P. (2009). Inhibitor of apoptosis proteins in Drosophila: gatekeepers of death. Apoptosis, Vol.14 (8), pp. 950-960.  show abstract

Bianchi, K. & Meier, P. (2009). A tangled web of ubiquitin chains: breaking news in TNF-R1 signaling. Mol cell, Vol.36 (5), pp. 736-742.  show abstract

Erturk-Hasdemir, D., Broemer, M., Leulier, F., Lane, W.S., Paquette, N., Hwang, D., Kim, C.H., Stoven, S., Meier, P. & Silverman, N., et al. (2009). Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes. P natl acad sci usa, Vol.106 (24), pp. 9779-9784.  show abstract

Gyrd-Hansen, M., Darding, M., Miasari, M., Santoro, M.M., Zender, L., Xue, W., Tenev, T., da Fonseca, P.C., Zvelebil, M., Bujnicki, J.M., et al. (2008). IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis. Nat cell biol, Vol.10 (11), pp. 1309-1317.  show abstract

Lhocine, N., Ribeiro, P.S., Buchon, N., Wepf, A., Wilson, R., Tenev, T., Lemaitre, B., Gstaiger, M., Meier, P. & Leulier, F., et al. (2008). PIMS modulates immune tolerance by negatively regulating Drosophila innate immune signaling. Cell host microbe, Vol.4 (2), pp. 147-158.  show abstract

Bardet, P.L., Kolahgar, G., Mynett, A., Miguel-Aliaga, I., Briscoe, J., Meier, P. & Vincent, J.P. (2008). A fluorescent reporter of caspase activity for live imaging. P natl acad sci usa, Vol.105 (37), pp. 13901-13905.  show abstract

Ditzel, M., Broemer, M., Tenev, T., Bolduc, C., Lee, T.V., Rigbolt, K.T., Elliott, R., Zvelebil, M., Blagoev, B., Bergmann, A., et al. (2008). Inactivation of effector caspases through nondegradative polyubiquitylation. Mol cell, Vol.32 (4), pp. 540-553.  show abstract

Tenev, T., Ditzel, M., Zachariou, A. & Meier, P. (2007). The antiapoptotic activity of insect IAPs requires activation by an evolutionarily conserved mechanism. Cell death differ, Vol.14 (6), pp. 1191-1201.  show abstract

Meier, P. & Vousden, K.H. (2007). Lucifer's labyrinth--ten years of path finding in cell death. Mol cell, Vol.28 (5), pp. 746-754.  show abstract

Ribeiro, P.S., Kuranaga, E., Tenev, T., Leulier, F., Miura, M. & Meier, P. (2007). DIAP2 functions as a mechanism-based regulator of drICE that contributes to the caspase activity threshold in living cells. J cell biol, Vol.179 (7), pp. 1467-1480.  show abstract

Leulier, F., Ribeiro, P.S., Palmer, E., Tenev, T., Takahashi, K., Robertson, D., Zachariou, A., Pichaud, F., Ueda, R. & Meier, P., et al. (2006). Systematic in vivo RNAi analysis of putative components of the Drosophila cell death machinery. Cell death differ, Vol.13 (10), pp. 1663-1674.  show abstract

Leulier, F., Lhocine, N., Lemaitre, B. & Meier, P. (2006). The Drosophila inhibitor of apoptosis protein DIAP2 functions in innate immunity and is essential to resist gram-negative bacterial infection. Mol cell biol, Vol.26 (21), pp. 7821-7831.  show abstract

Tenev, T., Zachariou, A., Wilson, R., Ditzel, M. & Meier, P. (2005). IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms. Nat cell biol, Vol.7 (1), pp. 70-77.  show abstract

Ditzel, M. & Meier, P. (2005). Ubiquitylation in apoptosis: DIAP1's (N-)en(d)igma. Cell death differ, Vol.12 (9), pp. 1208-1212.

Ditzel, M., Wilson, R., Tenev, T., Zachariou, A., Paul, A., Deas, E. & Meier, P. (2003). Degradation of DIAP1 by the N-end rule pathway is essential for regulating apoptosis. Nat cell biol, Vol.5 (5), pp. 467-473.  show abstract

Meier, P. & Silke, J. (2003). Programmed cell death: Superman meets Dr Death. Nat cell biol, Vol.5 (12), pp. 1035-1038.  show abstract

Zachariou, A., Tenev, T., Goyal, L., Agapite, J., Steller, H. & Meier, P. (2003). IAP-antagonists exhibit non-redundant modes of action through differential DIAP1 binding. Embo j, Vol.22 (24), pp. 6642-6652.  show abstract

Tenev, T., Zachariou, A., Wilson, R., Paul, A. & Meier, P. (2002). Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1. Embo j, Vol.21 (19), pp. 5118-5129.  show abstract

Wilson, R., Goyal, L., Ditzel, M., Zachariou, A., Baker, D.A., Agapite, J., Steller, H. & Meier, P. (2002). The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis. Nat cell biol, Vol.4 (6), pp. 445-450.  show abstract

Ditzel, M. & Meier, P. (2002). IAP degradation: decisive blow or altruistic sacrifice?. Trends cell biol, Vol.12 (10), pp. 449-452.  show abstract

Meier, P., Finch, A. & Evan, G. (2000). Apoptosis in development. Nature, Vol.407 (6805), pp. 796-801.  show abstract

Meier, P., neyen, C., runchel, C., schupfer, F. & lemaitre, B. The regulatory isoform rPGRP-LC resolves immune activation through receptor clearance via ESCRT-mediated trafficking. Nature immunology, .

Meier, P., kata, H., ditzel, M. & bergmann, A. An inhibitory mono-ubiquitylation of the Drosophila initiator caspase Dronc functions in both apoptotic and non-apoptotic pathways. Plos genetics, .

Annibaldi, A., Wicky John, S., Vanden Berghe, T., Swatek, K., Ruan, J., Liccardi, G., Bianchi, K., Komander, D., Choi, S., Coillie, S., et al. Ubiquitin-mediated regulation of RIPK1 kinase activity, independent of IKK and MK2. Molecular cell, .

Feltham, R., Jamal, K., Tenev, T., Liccardi, G., Jaco, I., Monteiro Domingues, C., Morris, O., Wicky John, S., Annibaldi, A., Widya, M., et al. Mind bomb regulates cell death during TNF signaling by suppressing RIPK1’s cytotoxic potential. Cell reports, .

Liccardi, G., Ramos Garcia, L., Tenev, T., Annibaldi, A., Legrand, A., Robertson, D., Darding, M., Bianchi, K. & Meier, P. RIPK1 and Caspase-8 ensure chromosome stability independently of their role in cell death and inflammation. Molecular cell, .


Book Chapters

Meier, P., Wållberg, F. & Tenev, T. Time-lapse imaging of necrosis. In McCall, K. & Klein, C. (Eds.), .