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Wilson, M., Andronesi, O., Barker, P.B., Bartha, R., Bizzi, A., Bolan, P.J., Brindle, K.M., Choi, I., Cudalbu, C., Dydak, U., et al. (2019). Methodological consensus on clinical proton MRS of the brain: Review and recommendations. Magnetic resonance in medicine, Vol.82 (2), pp. 527-550.

Carceller, F., Jerome, N.P., Fowkes, L.A., Khabra, K., Mackinnon, A., Bautista, F., Marshall, L.V., Vaidya, S., Mandeville, H., Morgan, V., et al. (2019). Post-radiotherapy apparent diffusion coefficient (ADC) in children and young adults with high-grade gliomas and diffuse intrinsic pontine gliomas. Pediatric hematology and oncology, Vol.36 (2), pp. 103-112.

Winfield, J.M., Miah, A.B., Strauss, D., Thway, K., Collins, D.J., deSouza, N.M., Leach, M.O., Morgan, V.A., Giles, S.L., Moskovic, E., et al. (2019). Utility of Multi-Parametric Quantitative Magnetic Resonance Imaging for Characterization and Radiotherapy Response Assessment in Soft-Tissue Sarcomas and Correlation With Histopathology. Frontiers in oncology, Vol.9.

Kousi, E., Smith, J., Ledger, A.E., Scurr, E., Allen, S., Wilson, R.M., O'Flynn, E., Pope, R.J., Leach, M.O. & Schmidt, M.A., et al. (2018). Quantitative evaluation of contrast agent uptake in standard fat-suppressed dynamic contrast-enhanced MRI examinations of the breast. Medical physics, Vol.45 (1), pp. 287-296.

Gurney-Champion, O.J., McQuaid, D., Dunlop, A., Wong, K.H., Welsh, L.C., Riddell, A.M., Koh, D.-., Oelfke, U., Leach, M.O., Nutting, C.M., et al. (2018). MRI-based Assessment of 3D Intrafractional Motion of Head and Neck Cancer for Radiation Therapy. International journal of radiation oncology*biology*physics, Vol.100 (2), pp. 306-316.

Wong, K.H., Panek, R., Dunlop, A., Mcquaid, D., Riddell, A., Welsh, L.C., Murray, I., Koh, D.-., Leach, M.O., Bhide, S.A., et al. (2018). Changes in multimodality functional imaging parameters early during chemoradiation predict treatment response in patients with locally advanced head and neck cancer. European journal of nuclear medicine and molecular imaging, Vol.45 (5), pp. 759-767.

Manias, K.A., Harris, L.M., Davies, N.P., Natarajan, K., MacPherson, L., Foster, K., Brundler, M.-., Hargrave, D.R., Payne, G.S., Leach, M.O., et al. (2018). Prospective multicentre evaluation and refinement of an analysis tool for magnetic resonance spectroscopy of childhood cerebellar tumours. Pediatric radiology, Vol.48 (11), pp. 1630-1641.

den Otter, L.A., Kaza, E., Kierkels, R.G., Meijers, A., Ubbels, F.J., Leach, M.O., Collins, D.J., Langendijk, J.A. & Knopf, A. (2018). Reproducibility of the lung anatomy under active breathing coordinator control: Dosimetric consequences for scanned proton treatments. Medical physics, Vol.45 (12), pp. 5525-5534.

Jerome, N.P., Miyazaki, K., Collins, D.J., Orton, M.R., d’Arcy, J.A., Wallace, T., Moreno, L., Pearson, A.D., Marshall, L.V., Carceller, F., et al. (2017). Repeatability of derived parameters from histograms following non-Gaussian diffusion modelling of diffusion-weighted imaging in a paediatric oncological cohort. European radiology, Vol.27 (1), pp. 345-353.

Ertas, G., Doran, S.J. & Leach, M.O. (2017). A computerized volumetric segmentation method applicable to multi-centre MRI data to support computer-aided breast tissue analysis, density assessment and lesion localization. Medical & biological engineering & computing, Vol.55 (1), pp. 57-68.

Welsh, L., Panek, R., Riddell, A., Wong, K., Leach, M.O., Tavassoli, M., Rahman, D., Schmidt, M., Hurley, T., Grove, L., et al. (2017). Blood transfusion during radical chemo-radiotherapy does not reduce tumour hypoxia in squamous cell cancer of the head and neck. British journal of cancer, Vol.116 (1), pp. 28-35.

Panek, R., Welsh, L., Baker, L.C., Schmidt, M.A., Wong, K.H., Riddell, A.M., Koh, D.-., Dunlop, A., Mcquaid, D., d'Arcy, J.A., et al. (2017). Noninvasive Imaging of Cycling Hypoxia in Head and Neck Cancer Using Intrinsic Susceptibility MRI. Clinical cancer research, Vol.23 (15), pp. 4233-4241.

Beloueche-Babari, M., Wantuch, S., Casals Galobart, T., Koniordou, M., Parkes, H.G., Arunan, V., Chung, Y.-., Eykyn, T.R., Smith, P.D. & Leach, M.O., et al. (2017). MCT1 Inhibitor AZD3965 Increases Mitochondrial Metabolism, Facilitating Combination Therapy and Noninvasive Magnetic Resonance Spectroscopy. Cancer research, Vol.77 (21), pp. 5913-5924.

Carceller, F., Jerome, N.P., Miyazaki, K., Collins, D.J., Orton, M.R., d'Arcy, J.A., Wallace, T., Moreno, L., Pearson, A.D., Zacharoulis, S., et al. (2017). Feasibility and applicability of diffusion-weighted and dynamic contrast-enhanced magnetic resonance imaging in routine assessments of children with high-grade gliomas. Pediatric blood & cancer, Vol.64 (2), pp. 279-283.

O'Connor, J.P., Aboagye, E.O., Adams, J.E., Aerts, H.J., Barrington, S.F., Beer, A.J., Boellaard, R., Bohndiek, S.E., Brady, M., Brown, G., et al. (2017). Imaging biomarker roadmap for cancer studies. Nature reviews clinical oncology, Vol.14 (3), pp. 169-186.

Kaza, E., Dunlop, A., Panek, R., Collins, D.J., Orton, M., Symonds-Tayler, R., McQuaid, D., Scurr, E., Hansen, V. & Leach, M.O., et al. (2017). Lung volume reproducibility under ABC control and self-sustained breath-holding. Journal of applied clinical medical physics, Vol.18 (2), pp. 154-162.

McClelland, J.R., Modat, M., Arridge, S., Grimes, H., D’Souza, D., Thomas, D., Connell, D.O., Low, D.A., Kaza, E., Collins, D.J., et al. (2017). A generalized framework unifying image registration and respiratory motion models and incorporating image reconstruction, for partial image data or full images. Physics in medicine and biology, Vol.62 (11), pp. 4273-4292.

Winfield, J.M., Tunariu, N., Rata, M., Miyazaki, K., Jerome, N.P., Germuska, M., Blackledge, M.D., Collins, D.J., de Bono, J.S., Yap, T.A., et al. (2017). Extracranial Soft-Tissue Tumors: Repeatability of Apparent Diffusion Coefficient Estimates from Diffusion-weighted MR Imaging. Radiology, Vol.284 (1), pp. 88-99.  show abstract

Doran, S.J., Hipwell, J.H., Denholm, R., Eiben, B., Busana, M., Hawkes, D.J., Leach, M.O. & Silva, I.D. (2017). Breast MRI segmentation for density estimation: Do different methods give the same results and how much do differences matter?. Medical physics, Vol.44 (9), pp. 4573-4592.

Borri, M., Gordon, K.D., Hughes, J.C., Scurr, E.D., Koh, D.-., Leach, M.O., Mortimer, P.S. & Schmidt, M.A. (2017). Magnetic Resonance Imaging–Based Assessment of Breast Cancer–Related Lymphoedema Tissue Composition. Investigative radiology, Vol.52 (9), pp. 554-561.

Phi, X.-., Houssami, N., Hooning, M.J., Riedl, C.C., Leach, M.O., Sardanelli, F., Warner, E., Trop, I., Saadatmand, S., Tilanus-Linthorst, M.M., et al. (2017). Accuracy of screening women at familial risk of breast cancer without a known gene mutation: Individual patient data meta-analysis. European journal of cancer, Vol.85, pp. 31-38.

Agliano, A., Balarajah, G., Ciobota, D.M., Sidhu, J., Clarke, P.A., Jones, C., Workman, P., Leach, M.O. & Al-Saffar, N.M. (2017). Pediatric and adult glioblastoma radiosensitization induced by PI3K/mTOR inhibition causes early metabolic alterations detected by nuclear magnetic resonance spectroscopy. Oncotarget, Vol.8 (29).

Fong, A.-., Thavasu, P., Gagrica, S., Swales, K.E., Leach, M.O., Cosulich, S.C., Chung, Y.-. & Banerji, U. (2017). Evaluation of the combination of the dual m-TORC1/2 inhibitor vistusertib (AZD2014) and paclitaxel in ovarian cancer models. Oncotarget, Vol.8 (69).

Chung, Y.-., Leach, M.O. & Eykyn, T.R. (2017). Magnetic Resonance Spectroscopy to Study Glycolytic Metabolism During Autophagy. , , pp. 133-153.

Blackledge, M.D., Collins, D.J., Koh, D.-. & Leach, M.O. (2016). Rapid development of image analysis research tools: Bridging the gap between researcher and clinician with pyOsiriX. Computers in biology and medicine, Vol.69, pp. 203-212.

Phi, X.-., Saadatmand, S., De Bock, G.H., Warner, E., Sardanelli, F., Leach, M.O., Riedl, C.C., Trop, I., Hooning, M.J., Mandel, R., et al. (2016). Contribution of mammography to MRI screening in BRCA mutation carriers by BRCA status and age: individual patient data meta-analysis. British journal of cancer, Vol.114 (6), pp. 631-637.

Orton, M.R., Messiou, C., Collins, D., Morgan, V.A., Tessier, J., Young, H., deSouza, N. & Leach, M.O. (2016). Diffusion-weighted MR imaging of metastatic abdominal and pelvic tumours is sensitive to early changes induced by a VEGF inhibitor using alternative diffusion attenuation models. European radiology, Vol.26 (5), pp. 1412-1419.

Rata, M., Collins, D.J., Darcy, J., Messiou, C., Tunariu, N., Desouza, N., Young, H., Leach, M.O. & Orton, M.R. (2016). Assessment of repeatability and treatment response in early phase clinical trials using DCE-MRI: comparison of parametric analysis using MR- and CT-derived arterial input functions. European radiology, Vol.26 (7), pp. 1991-1998.

Kousi, E., Borri, M., Dean, J., Panek, R., Scurr, E., Leach, M.O. & Schmidt, M.A. (2016). Quality assurance in MRI breast screening: comparing signal-to-noise ratio in dynamic contrast-enhanced imaging protocols. Physics in medicine and biology, Vol.61 (1), pp. 37-49.

O'Flynn, E.A., Blackledge, M., Collins, D., Downey, K., Doran, S., Patel, H., Dumonteil, S., Mok, W., Leach, M.O. & Koh, D.-., et al. (2016). Evaluating the diagnostic sensitivity of computed diffusion-weighted MR imaging in the detection of breast cancer. Journal of magnetic resonance imaging, Vol.44 (1), pp. 130-137.

Panek, R., Welsh, L., Dunlop, A., Wong, K.H., Riddell, A.M., Koh, D.-., Schmidt, M.A., Doran, S., Mcquaid, D., Hopkinson, G., et al. (2016). Repeatability and sensitivity of T2* measurements in patients with head and neck squamous cell carcinoma at 3T. Journal of magnetic resonance imaging, Vol.44 (1), pp. 72-80.

Perez-Lopez, R., Lorente, D., Blackledge, M.D., Collins, D.J., Mateo, J., Bianchini, D., Omlin, A., Zivi, A., Leach, M.O., de Bono, J.S., et al. (2016). Volume of Bone Metastasis Assessed with Whole-Body Diffusion-weighted Imaging Is Associated with Overall Survival in Metastatic Castration-resistant Prostate Cancer. Radiology, Vol.280 (1), pp. 151-160.

Borri, M., Scurr, E.D., Richardson, C., Usher, M., Leach, M.O. & Schmidt, M.A. (2016). A novel approach to evaluate spatial resolution of MRI clinical images for optimization and standardization of breast screening protocols. Medical physics, Vol.43 (12), pp. 6354-6363.

Carceller, F., Fowkes, L.A., Khabra, K., Moreno, L., Saran, F., Burford, A., Mackay, A., Jones, D.T., Hovestadt, V., Marshall, L.V., et al. (2016). Pseudoprogression in children, adolescents and young adults with non-brainstem high grade glioma and diffuse intrinsic pontine glioma. Journal of neuro-oncology, Vol.129 (1), pp. 109-121.

Schmidt, M.A., Panek, R., Colgan, R., Hughes, J., Sohaib, A., Saran, F., Murray, J., Bernard, J., Revell, P., Nittka, M., et al. (2016). Slice Encoding for Metal Artefact Correction in magnetic resonance imaging examinations for radiotherapy planning. Radiotherapy and oncology, Vol.120 (2), pp. 356-362.

Jerome, N.P., Boult, J.K., Orton, M.R., d’Arcy, J., Collins, D.J., Leach, M.O., Koh, D.-. & Robinson, S.P. (2016). Modulation of renal oxygenation and perfusion in rat kidney monitored by quantitative diffusion and blood oxygen level dependent magnetic resonance imaging on a clinical 1 5T platform. Bmc nephrology, Vol.17 (1).

Denholm, R., De Stavola, B., Hipwell, J.H., Doran, S.J., Busana, M.C., Eng, A., Jeffreys, M., Leach, M.O., Hawkes, D. & dos Santos Silva, I., et al. (2016). Pre-natal exposures and breast tissue composition: findings from a British pre-birth cohort of young women and a systematic review. Breast cancer research, Vol.18 (1).

Delgado-Goni, T., Miniotis, M.F., Wantuch, S., Parkes, H.G., Marais, R., Workman, P., Leach, M.O. & Beloueche-Babari, M. (2016). The BRAF Inhibitor Vemurafenib Activates Mitochondrial Metabolism and Inhibits Hyperpolarized Pyruvate–Lactate Exchange in BRAF-Mutant Human Melanoma Cells. Molecular cancer therapeutics, Vol.15 (12), pp. 2987-2999.

Panek, R., Schmidt, M.A., Borri, M., Koh, D.-., Riddell, A., Welsh, L., Dunlop, A., Powell, C., Bhide, S.A., Nutting, C.M., et al. (2016). Time-resolved angiography with stochastic trajectories for dynamic contrast-enhanced MRI in head and neck cancer: Are pharmacokinetic parameters affected?. Medical physics, Vol.43 (11), pp. 6024-6032.

Jerome, N.P., Papoutsaki, M.-., Orton, M.R., Parkes, H.G., Winfield, J.M., Boss, M.A., Leach, M.O., deSouza, N.M. & Collins, D.J. (2016). Development of a temperature-controlled phantom for magnetic resonance quality assurance of diffusion, dynamic, and relaxometry measurements. Medical physics, Vol.43 (6Part1), pp. 2998-3007.

Jerome, N.P., d’Arcy, J.A., Feiweier, T., Koh, D.-., Leach, M.O., Collins, D.J. & Orton, M.R. (2016). Extended T2-IVIM model for correction of TE dependence of pseudo-diffusion volume fraction in clinical diffusion-weighted magnetic resonance imaging. Physics in medicine and biology, Vol.61 (24), pp. N667-N680.

Cheng, L., Blackledge, M.D., Collins, D.J., Orton, M.R., Jerome, N.P., Feiweier, T., Rata, M., Morgan, V., Tunariu, N., Leach, M.O., et al. (2016). T2-adjusted computed diffusion-weighted imaging: A novel method to enhance tumour visualisation. Comp. in bio. and med., Vol.79, pp. 92-98.

Phi, X.-., Houssami, N., Obdeijn, I.-., Warner, E., Sardanelli, F., Leach, M.O., Riedl, C.C., Trop, I., Tilanus-Linthorst, M.M., Mandel, R., et al. (2015). Magnetic resonance imaging improves breast screening sensitivity in BRCA mutation carriers age ≥ 50 years: evidence from an individual patient data meta-analysis. J clin oncol, Vol.33 (4), pp. 349-356.  show abstract

Lee, C.P., Taylor, N.J., Attard, G., Pacey, S., Nathan, P.D., de Bono, J.S., Temple, G., Bell, S., Stefanic, M., Stopfer, P., et al. (2015). Phase I Study of Nintedanib Incorporating Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Patients With Advanced Solid Tumors. The oncologist, Vol.20 (4), pp. 368-369.

Kaza, E., Collins, D., Symonds-Tayler, R., McDonald, F., Scurr, E., McNair, H., Hansen, V. & Leach, M. (2015). 143: Magnetic resonance imaging (MRI) in patients with non-small cell lung cancer (NSCLC) using active breathing coordinator motion control. Lung cancer, Vol.87, pp. S52-S52.

Harris, L.M., Tunariu, N., Messiou, C., Hughes, J., Wallace, T., DeSouza, N.M., Leach, M.O. & Payne, G.S. (2015). Evaluation of lactate detection using selective multiple quantum coherence in phantoms and brain tumours. Nmr biomed, Vol.28 (3), pp. 338-343.  show abstract

Beloueche-Babari, M., Box, C., Arunan, V., Parkes, H.G., Valenti, M., De Haven Brandon, A., Jackson, L.E., Eccles, S.A. & Leach, M.O. (2015). Acquired resistance to EGFR tyrosine kinase inhibitors alters the metabolism of human head and neck squamous carcinoma cells and xenograft tumours. British journal of cancer, Vol.112 (7), pp. 1206-1214.

Payne, G.S., deSouza, N.M., Messiou, C. & Leach, M.O. (2015). Single-shot single-voxel lactate measurements using FOCI-LASER and a multiple-quantum filter. Nmr in biomedicine, Vol.28 (4), pp. 496-504.

Grech-Sollars, M., Hales, P.W., Miyazaki, K., Raschke, F., Rodriguez, D., Wilson, M., Gill, S.K., Banks, T., Saunders, D.E., Clayden, J.D., et al. (2015). Multi-centre reproducibility of diffusion MRI parameters for clinical sequences in the brain. Nmr in biomedicine, Vol.28 (4), pp. 468-485.

Borri, M., Schmidt, M.A., Gordon, K.D., Wallace, T.A., Hughes, J.C., Scurr, E.D., Koh, D.-., Leach, M.O. & Mortimer, P.S. (2015). Quantitative Contrast-Enhanced Magnetic Resonance Lymphangiography of the Upper Limbs in Breast Cancer Related Lymphedema: An Exploratory Study. Lymphatic research and biology, Vol.13 (2), pp. 100-106.

Miyazaki, K., Jerome, N.P., Collins, D.J., Orton, M.R., d’Arcy, J.A., Wallace, T., Moreno, L., Pearson, A.D., Marshall, L.V., Carceller, F., et al. (2015). Demonstration of the reproducibility of free-breathing diffusion-weighted MRI and dynamic contrast enhanced MRI in children with solid tumours: a pilot study. European radiology, Vol.25 (9), pp. 2641-2650.

McErlean, C.M., Boult, J.K., Collins, D.J., Leach, M.O., Robinson, S.P. & Doran, S.J. (2015). Detecting microvascular changes in the mouse spleen using optical computed tomography. Microvascular research, Vol.101, pp. 96-102.

Wardlaw, J.M., Davies, H., Booth, T.C., Laurie, G., Compston, A., Freeman, C., Leach, M.O., Waldman, A.D., Lomas, D.J., Kessler, K., et al. (2015). Acting on incidental findings in research imaging. Bmj, Vol.351 (nov10 1), pp. h5190-h5190.

Andreou, A., Sohaib, A., Collins, D.J., Takahara, T., Kwee, T.C., Leach, M.O., MacVicar, D.A. & Koh, D.-. (2015). Diffusion-weighted MR neurography for the assessment of brachial plexopathy in oncological practice. Cancer imaging, Vol.15 (1).

Welsh, L., Panek, R., McQuaid, D., Dunlop, A., Schmidt, M., Riddell, A., Koh, D.-., Doran, S., Murray, I., Du, Y., et al. (2015). Prospective, longitudinal, multi-modal functional imaging for radical chemo-IMRT treatment of locally advanced head and neck cancer: the INSIGHT study. Radiation oncology, Vol.10 (1).

Cheng, L., Tunariu, N., Collins, D.J., Blackledge, M.D., Riddell, A.M., Leach, M.O., Popat, S. & Koh, D.-. (2015). Response evaluation in mesothelioma: Beyond RECIST. Lung cancer, Vol.90 (3), pp. 433-441.

Kaza, E., Symonds-Tayler, R., Collins, D.J., McDonald, F., McNair, H.A., Scurr, E., Koh, D.-. & Leach, M.O. (2015). First MRI application of an active breathing coordinator. Phys med biol, Vol.60 (4), pp. 1681-1696.  show abstract

Jerome, N.P., Orton, M.R., d'Arcy, J.A., Feiweier, T., Tunariu, N., Koh, D.-., Leach, M.O. & Collins, D.J. (2015). Use of the temporal median and trimmed mean mitigates effects of respiratory motion in multiple-acquisition abdominal diffusion imaging. Phys med biol, Vol.60 (2), pp. N9-20.  show abstract

Panek, R., Borri, M., Orton, M., O'Flynn, E., Morgan, V., Giles, S.L., deSouza, N., Leach, M.O. & Schmidt, M.A. (2015). Evaluation of diffusion models in breast cancer. Medical physics, Vol.42 (8), pp. 4833-4839.

Orton, M.R., Collins, D.J., Koh, D.-. & Leach, M.O. (2014). Improved intravoxel incoherent motion analysis of diffusion weighted imaging by data driven Bayesian modeling. Magn reson med, Vol.71 (1), pp. 411-420.  show abstract

Jerome, N.P., Orton, M.R., d'Arcy, J.A., Collins, D.J., Koh, D.-. & Leach, M.O. (2014). Comparison of free-breathing with navigator-controlled acquisition regimes in abdominal diffusion-weighted magnetic resonance images: Effect on ADC and IVIM statistics. J magn reson imaging, Vol.39 (1), pp. 235-240.  show abstract

Rata, M., Giles, S.L., deSouza, N.M., Leach, M.O. & Payne, G.S. (2014). Comparison of three reference methods for the measurement of intracellular pH using P-31 MRS in healthy volunteers and patients with lymphoma. Nmr in biomedicine, Vol.27 (2), pp. 158-162.

Öz, G., Alger, J.R., Barker, P.B., Bartha, R., Bizzi, A., Boesch, C., Bolan, P.J., Brindle, K.M., Cudalbu, C., Dinçer, A., et al. (2014). Clinical Proton MR Spectroscopy in Central Nervous System Disorders. Radiology, Vol.270 (3), pp. 658-679.

Gareth, E.D., Nisha, K., Yit, L., Soujanye, G., Emma, H., Massat, N.J., Maxwell, A.J., Sarah, I., Rosalind, E., Leach, M.O., et al. (2014). MRI breast screening in high-risk women: cancer detection and survival analysis. Breast cancer research and treatment, Vol.145 (3), pp. 663-672.

Spinks, T.J., Karia, D., Leach, M.O. & Flux, G. (2014). Quantitative PET and SPECT performance characteristics of the Albira Trimodal pre-clinical tomograph. Phys med biol, Vol.59 (3), pp. 715-731.  show abstract

Evans, D.G., Kesavan, N., Lim, Y., Gadde, S., Hurley, E., Massat, N.J., Maxwell, A.J., Ingham, S., Eeles, R., Leach, M.O., et al. (2014). MRI breast screening in high-risk women: cancer detection and survival analysis (vol 145, pg 663, 2014). Breast cancer research and treatment, Vol.147 (3), pp. 691-691.

Ledger, A.E., Borri, M., Pope, R.J., Scurr, E.D., Wallace, T., Richardson, C., Usher, M., Allen, S., Wilson, R.M., Thomas, K., et al. (2014). Investigating the influence of flip angle and k-space sampling on dynamic contrast-enhanced MRI breast examinations. Acad radiol, Vol.21 (11), pp. 1394-1401.  show abstract

Lin, G., Hill, D.K., Andrejeva, G., Boult, J.K., Troy, H., Fong, A.-., Orton, M.R., Panek, R., Parkes, H.G., Jafar, M., et al. (2014). Dichloroacetate induces autophagy in colorectal cancer cells and tumours. Br j cancer, Vol.111 (2), pp. 375-385.  show abstract

Yap, T.A., Yan, L., Patnaik, A., Tunariu, N., Biondo, A., Fearen, I., Papadopoulos, K.P., Olmos, D., Baird, R., Delgado, L., et al. (2014). Interrogating two schedules of the AKT inhibitor MK-2206 in patients with advanced solid tumors incorporating novel pharmacodynamic and functional imaging biomarkers. Clin cancer res, Vol.20 (22), pp. 5672-5685.  show abstract

Blackledge, M.D., Collins, D.J., Tunariu, N., Orton, M.R., Padhani, A.R., Leach, M.O. & Koh, D.-. (2014). Assessment of treatment response by total tumor volume and global apparent diffusion coefficient using diffusion-weighted MRI in patients with metastatic bone disease: a feasibility study. Plos one, Vol.9 (4), p. e91779.  show abstract

Lin, G., Andrejeva, G., Wong Te Fong, A.-., Hill, D.K., Orton, M.R., Parkes, H.G., Koh, D.-., Robinson, S.P., Leach, M.O., Eykyn, T.R., et al. (2014). Reduced Warburg effect in cancer cells undergoing autophagy: steady- state 1H-MRS and real-time hyperpolarized 13C-MRS studies. Plos one, Vol.9 (3), p. e92645.  show abstract

Al-Saffar, N.M., Marshall, L.V., Jackson, L.E., Balarajah, G., Eykyn, T.R., Agliano, A., Clarke, P.A., Jones, C., Workman, P., Pearson, A.D., et al. (2014). Lactate and choline metabolites detected in vitro by nuclear magnetic resonance spectroscopy are potential metabolic biomarkers for PI3K inhibition in pediatric glioblastoma. Plos one, Vol.9 (8), p. e103835.  show abstract

Sherwood, V., Civale, J., Rivens, I., Collins, D.J., Leach, M.O. & ter Haar, G.R. (2014). Development of a hybrid magnetic resonance and ultrasound imaging system. Biomed res int, Vol.2014, p. 914347.  show abstract

Falck Miniotis, M., Arunan, V., Eykyn, T.R., Marais, R., Workman, P., Leach, M.O. & Beloueche-Babari, M. (2013). MEK1/2 inhibition decreases lactate in BRAF-driven human cancer cells. Cancer res, Vol.73 (13), pp. 4039-4049.  show abstract

Tilanus-Linthorst, M.M., Lingsma, H.F., Evans, D.G., Thompson, D., Kaas, R., Manders, P., van Asperen, C.J., Adank, M., Hooning, M.J., Lim, G.E., et al. (2013). Optimal age to start preventive measures in women with BRCA1/2 mutations or high familial breast cancer risk. International journal of cancer, Vol.133 (1), pp. 156-163.

Andreou, A., Koh, D.M., Collins, D.J., Blackledge, M., Wallace, T., Leach, M.O. & Orton, M.R. (2013). Measurement reproducibility of perfusion fraction and pseudodiffusion coefficient derived by intravoxel incoherent motion diffusion-weighted MR imaging in normal liver and metastases. Eur radiol, Vol.23 (2), pp. 428-434.  show abstract

Goh, V., Schaeffter, T. & Leach, M. (2013). Reproducibility of Dynamic Contrast-enhanced MR Imaging: Why We Should Care. Radiology, Vol.266 (3), pp. 698-700.

Kaffanke, J.B., Romanzetti, S., Dierkes, T., Leach, M.O., Balcom, B.J. & Shah, N.J. (2013). Multi-Frame SPRITE: A method for resolution enhancement of multiple-point SPRITE data. Journal of magnetic resonance, Vol.230, pp. 111-116.

Schmidt, M.A., Borri, M., Scurr, E., Ertas, G., Payne, G., O'Flynn, E., Desouza, N. & Leach, M.O. (2013). Breast dynamic contrast-enhanced examinations with fat suppression: are contrast-agent uptake curves affected by magnetic field inhomogeneity?. Eur radiol, Vol.23 (6), pp. 1537-1545.  show abstract

Shin, H.-., Orton, M.R., Collins, D.J., Doran, S.J. & Leach, M.O. (2013). Stacked autoencoders for unsupervised feature learning and multiple organ detection in a pilot study using 4D patient data. Ieee trans pattern anal mach intell, Vol.35 (8), pp. 1930-1943.  show abstract

Hill, D.K., Jamin, Y., Orton, M.R., Tardif, N., Parkes, H.G., Robinson, S.P., Leach, M.O., Chung, Y.-. & Eykyn, T.R. (2013). ¹H NMR and hyperpolarized ¹³C NMR assays of pyruvate-lactate: a comparative study. Nmr biomed, Vol.26 (10), pp. 1321-1325.  show abstract

Tam, H.H., Collins, D.J., Brown, G., Chau, I., Cunningham, D., Leach, M.O. & Koh, D.-. (2013). The role of pre-treatment diffusion-weighted MRI in predicting long-term outcome of colorectal liver metastasis. Br j radiol, Vol.86 (1030), p. 20130281.  show abstract

Yap, T.A., Arkenau, H.-., Camidge, D.R., George, S., Serkova, N.J., Gwyther, S.J., Spratlin, J.L., Lal, R., Spicer, J., Desouza, N.M., et al. (2013). First-in-human phase I trial of two schedules of OSI-930, a novel multikinase inhibitor, incorporating translational proof-of-mechanism studies. Clin cancer res, Vol.19 (4), pp. 909-919.  show abstract

Beloueche-Babari, M., Jamin, Y., Arunan, V., Walker-Samuel, S., Revill, M., Smith, P.D., Halliday, J., Waterton, J.C., Barjat, H., Workman, P., et al. (2013). Acute tumour response to the MEK1/2 inhibitor selumetinib (AZD6244, ARRY-142886) evaluated by non-invasive diffusion-weighted MRI. Br j cancer, Vol.109 (6), pp. 1562-1569.  show abstract

Chung, Y.-., El Akabawy, G., So, P.-., Solanky, B.S., Leach, M.O. & Modo, M. (2013). Profiling metabolite changes in the neuronal differentiation of human striatal neural stem cells using 1H-magnetic resonance spectroscopy. Neuroreport, Vol.24 (18), pp. 1035-1040.  show abstract

Blackledge, M.D., Koh, D.M., Collins, D.J., Chua, S. & Leach, M.O. (2013). The utility of whole-body diffusion-weighted MRI for delineating regions of interest in PET. Nuclear instruments & methods in physics research section a-accelerators spectrometers detectors and associated equipment, Vol.702, pp. 148-151.

Hill, D.K., Orton, M.R., Mariotti, E., Boult, J.K., Panek, R., Jafar, M., Parkes, H.G., Jamin, Y., Miniotis, M.F., Al-Saffar, N.M., et al. (2013). Model free approach to kinetic analysis of real-time hyperpolarized 13C magnetic resonance spectroscopy data. Plos one, Vol.8 (9), p. e71996.  show abstract

Eccles, S.A., Aboagye, E.O., Ali, S., Anderson, A.S., Armes, J., Berditchevski, F., Blaydes, J.P., Brennan, K., Brown, N.J., Bryant, H.E., et al. (2013). Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer. Breast cancer research, Vol.15 (5).

Rodrigues, L.M., Chung, Y.L., Al Saffar, N.M., Sharp, S.Y., Jackson, L.E., Banerji, U., Stubbs, M., Leach, M.O., Griffiths, J.R. & Workman, P., et al. (2012). Effects of HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin (17-AAG) on NEU/HER2 overexpressing mammary tumours in MMTV-NEU-NT mice monitored by Magnetic Resonance Spectroscopy. Bmc research notes, Vol.5, p. 250.  show abstract  full text

Koh, D.M., Blackledge, M., Padhani, A.R., Takahara, T., Kwee, T.C., Leach, M.O. & Collins, D.J. (2012). Whole-body diffusion-weighted MRI: tips, tricks, and pitfalls. American journal of roentgenology, Vol.199 (2), pp. 252-262.

Scurr, E.D., Collins, D.J., Temple, L., Karanjia, N., Leach, M.O. & Koh, D.-. (2012). Appearances of colorectal hepatic metastases at diffusion-weighted MRI compared with histopathology: initial observations. Br j radiol, Vol.85 (1011), pp. 225-230.  show abstract

Raza, S.A., Funicelli, L., Sohaib, S.A., Collins, D.J., Scurr, E., Leach, M.O. & Koh, D.-. (2012). Assessment of colorectal hepatic metastases by quantitative T2 relaxation time. Eur j radiol, Vol.81 (4), pp. e536-e540.  show abstract

Miyazaki, K., Orton, M.R., Davidson, R.L., d'Arcy, J.A., Lewington, V., Koh, T.S., Thng, C.H., Leach, M.O., Collins, D.J. & Koh, D.-., et al. (2012). Neuroendocrine tumor liver metastases: use of dynamic contrast-enhanced MR imaging to monitor and predict radiolabeled octreotide therapy response. Radiology, Vol.263 (1), pp. 139-148.  show abstract

Germuska, M., Tunariu, N., Leach, M.O., Xu, J. & Payne, G.S. (2012). An evaluation of motion compensation strategies and repeatability for abdominal (1)H MR spectroscopy measurements in volunteer studies and clinical trials. Nmr biomed, Vol.25 (6), pp. 859-865.  show abstract

Leach, M.O., Morgan, B., Tofts, P.S., Buckley, D.L., Huang, W., Horsfield, M.A., Chenevert, T.L., Collins, D.J., Jackson, A., Lomas, D., et al. (2012). Imaging vascular function for early stage clinical trials using dynamic contrast-enhanced magnetic resonance imaging. Eur radiol, Vol.22 (7), pp. 1451-1464.  show abstract

Vachon, C.M., Scott, C.G., Fasching, P.A., Hall, P., Tamimi, R.M., Li, J., Stone, J., Apicella, C., Odefrey, F., Gierach, G.L., et al. (2012). Common breast cancer susceptibility variants in LSP1 and RAD51L1 are associated with mammographic density measures that predict breast cancer risk. Cancer epidemiol biomarkers prev, Vol.21 (7), pp. 1156-1166.  show abstract

Koh, D.-., Blackledge, M., Padhani, A.R., Takahara, T., Kwee, T.C., Leach, M.O. & Collins, D.J. (2012). Whole-body diffusion-weighted MRI: tips, tricks, and pitfalls. Ajr am j roentgenol, Vol.199 (2), pp. 252-262.  show abstract

Heijnsdijk, E.A., Warner, E., Gilbert, F.J., Tilanus-Linthorst, M.M., Evans, G., Causer, P.A., Eeles, R.A., Kaas, R., Draisma, G., Ramsay, E.A., et al. (2012). Differences in natural history between breast cancers in BRCA1 and BRCA2 mutation carriers and effects of MRI screening-MRISC, MARIBS, and Canadian studies combined. Cancer epidemiol biomarkers prev, Vol.21 (9), pp. 1458-1468.  show abstract

Messiou, C., Orton, M., Ang, J.E., Collins, D.J., Morgan, V.A., Mears, D., Castellano, I., Papadatos-Pastos, D., Brunetto, A., Tunariu, N., et al. (2012). Advanced solid tumors treated with cediranib: comparison of dynamic contrast-enhanced MR imaging and CT as markers of vascular activity. Radiology, Vol.265 (2), pp. 426-436.  show abstract

Doran, S.J., d'Arcy, J., Collins, D.J., Andriantsimiavona, R., Orton, M., Koh, D.-. & Leach, M.O. (2012). Informatics in radiology: development of a research PACS for analysis of functional imaging data in clinical research and clinical trials. Radiographics, Vol.32 (7), pp. 2135-2150.  show abstract

Koh, D.-., Blackledge, M., Burns, S., Hughes, J., Stemmer, A., Kiefer, B., Leach, M.O. & Collins, D.J. (2012). Combination of chemical suppression techniques for dual suppression of fat and silicone at diffusion-weighted MR imaging in women with breast implants. Eur radiol, Vol.22 (12), pp. 2648-2653.  show abstract

Peet, A.C., Arvanitis, T.N., Leach, M.O. & Waldman, A.D. (2012). Functional imaging in adult and paediatric brain tumours. Nat rev clin oncol, Vol.9 (12), pp. 700-711.  show abstract

Beloueche-Babari, M., Arunan, V., Troy, H., te Poele, R.H., te Fong, A.-., Jackson, L.E., Payne, G.S., Griffiths, J.R., Judson, I.R., Workman, P., et al. (2012). Histone deacetylase inhibition increases levels of choline kinase α and phosphocholine facilitating noninvasive imaging in human cancers. Cancer res, Vol.72 (4), pp. 990-1000.  show abstract

Nathan, P., Zweifel, M., Padhani, A.R., Koh, D.-., Ng, M., Collins, D.J., Harris, A., Carden, C., Smythe, J., Fisher, N., et al. (2012). Phase I trial of combretastatin A4 phosphate (CA4P) in combination with bevacizumab in patients with advanced cancer. Clin cancer res, Vol.18 (12), pp. 3428-3439.  show abstract

Tilanus-Linthorst, M.M., Lingsma, H., Evans, G.D., Kaas, R., Manders, P., Hooning, M.J., van Asperen, C.J., Thompson, D., Eeles, R., Oosterwijk, J.C., et al. (2012). Abstract P4-11-05: Optimal age to start preventive measures in women with BRCA1/2 mutations or high familial breast cancer risk. Poster session abstracts, .

Wong Te Fong, A.-., Eykyn, T.R., Parkes, H.G., Bielen, A., Jones, C., Judson, I.R., Griffiths, J.R., Leach, M.O. & Chung, Y.-. (2012). Abstract B61: Picropodophyllin (PPP) increases glucose metabolism and lactate production in paediatric glioblastoma cells. Clinical cancer research, Vol.18 (10_Supplement), pp. B61-B61.

Shin, H.C., Orton, M.R., Collins, D.J., Doran, S.J. & Leach, M.O. (2012). Stacked Autoencoders for Unsupervised Feature Learning and Multiple Organ Detection in a Pilot Study Using 4D Patient Data. Ieee trans pattern anal mach intell, .  show abstract

Koh, D.M., Blackledge, M., Burns, S., Hughes, J., Stemmer, A., Kiefer, B., Leach, M.O. & Collins, D.J. (2012). Combination of chemical suppression techniques for dual suppression of fat and silicone at diffusion-weighted MR imaging in women with breast implants. European radiology, Vol.22 (12), pp. 2648-2653.

Koh, T.S., Thng, C.H., Hartono, S., Kwek, J.W., Khoo, J.B., Miyazaki, K., Collins, D.J., Orton, M.R., Leach, M.O., Lewington, V., et al. (2011). Dynamic Contrast-Enhanced MRI of Neuroendocrine Hepatic Metastases: A Feasibility Study Using a Dual-Input Two-Compartment Model. Magn reson med, Vol.65 (1), pp. 250-260.  show abstract

Beloueche-Babari, M., Workman, P. & Leach, M.O. (2011). Exploiting tumor metabolism for non-invasive imaging of the therapeutic activity of molecularly targeted anticancer agents. Cell cycle, Vol.10 (17), pp. 2883-2893.  show abstract

Blackledge, M.D., Leach, M.O., Collins, D.J. & Koh, D.M. (2011). Computed diffusion-weighted MR imaging may improve tumor detection. Radiology, Vol.261 (2), pp. 573-581.  show abstract

Hunter, C.J., Scurr, E., Jeyadevan, N., Collins, D.J., Abulafi, M., Tekkis, P.P., Georgiou, P.A., Leach, M.O. & Brown, G. (2011). Optimising magnetic resonance imaging for preoperative staging and surgical planning in colon cancer at 1 5 tesla and 3 0 tesla. Journal of clinical oncology, Vol.29 (4).

Kurhanewicz, J., Vigneron, D.B., Brindle, K., Chekmenev, E.Y., Comment, A., Cunningham, C.H., DeBerardinis, R.J., Green, G.G., Leach, M.O., Rajan, S.S., et al. (2011). Analysis of Cancer Metabolism by Imaging Hyperpolarized Nuclei: Prospects for Translation to Clinical Research. Neoplasia, Vol.13 (2), pp. 81-97.  show abstract

Hunter, C.J., Scurr, E., Jeyadevan, N., Collins, D.J., Abulafi, M., Tekkis, P.P., Georgiou, P.A., Leach, M.O. & Brown, G. (2011). Optimising magnetic resonance imaging for preoperative staging and surgical planning in colon cancer at 1 5 tesla and 3 0 tesla. J clin oncol, Vol.29 (4_suppl), p. 395.  show abstract

Just, N., Koh, D.M., D'Arcy, J., Collins, D.J. & Leach, M.O. (2011). Assessment of the effect of haematocrit-dependent arterial input functions on the accuracy of pharmacokinetic parameters in dynamic contrast-enhanced MRI. Nmr biomed, .  show abstract

Whitcher, B., Schmid, V.J., Collins, D.J., Orton, M.R., Koh, D.M., de Corcuera, I.D., Parera, M., del Campo, J.M., deSouza, N.M., Leach, M.O., et al. (2011). A Bayesian hierarchical model for DCE-MRI to evaluate treatment response in a phase II study in advanced squamous cell carcinoma of the head and neck. Magn reson mater phy, Vol.24 (2), pp. 85-96.  show abstract

Yap, T.A., Olmos, D., Brunetto, A.T., Tunariu, N., Barriuso, J., Riisnaes, R., Pope, L., Clark, J., Futreal, A., Germuska, M., et al. (2011). Phase I Trial of a Selective c-MET Inhibitor ARQ 197 Incorporating Proof of Mechanism Pharmacodynamic Studies. J clin oncol, Vol.29 (10), pp. 1271-1279.  show abstract

Blackledge, M.D., Leach, M.O., Collins, D.J. & Koh, D.-. (2011). Computed diffusion-weighted MR imaging may improve tumor detection. Radiology, Vol.261 (2), pp. 573-581.  show abstract

Hutton, J., Walker, L.G., Gilbert, F.J., Evans, D.G., Eeles, R., Kwan-Lim, G.E., Thompson, D., Pointon, L.J., Sharp, D.M., Leach, M.O., et al. (2011). Psychological impact and acceptability of magnetic resonance imaging and X-ray mammography: the MARIBS Study. Brit j cancer, Vol.104 (4), pp. 578-586.  show abstract

Bahn, J.D., Skipper, J., Garcia, A., Jiang, P., Osgood, R., Symons, R., Frost, G.I., Shepard, H., Thompson, C.B. & Li, X., et al. (2011). Abstract 2501: PEGylated human recombinant hyaluronidase (PEGPH20) enhances radiotherapy in hyaluronan-rich solid tumors. Tumor biology, .

Beloueche-Babari, M., Arunan, V., Troy, H., Jackson, L.E., Wong, A.-., Workman, P., Judson, I., Griffiths, J.R., Leach, M.O. & Chung, Y.-., et al. (2011). Abstract 5277: Non-invasive metabolic biomarkers of histone deacetylase inhibition in human colon cancer cells and tumors. Tumor biology, .

Chung, Y.-., Lin, G., Troy, H., Fong, A.-., Jackson, L.E., Hill, D.K., Orton, M., Koh, D.-., Robinson, S.P., Judson, I.R., et al. (2011). Abstract 3788: Autophagy induced by DCA, PI3K inhibition or starvation results in reduced lactate production measured in real-time by DNP 13C MRS. Cellular and molecular biology, .

Leary, A., Pickering, L.M., Larkin, J.M., Leach, M.O., Gore, M.E., Sohaib, A., Collins, D.J. & Koh, D. (2011). Quantitative diffusion-weighted (DW) MR imaging of microcapillary perfusion and tissue diffusivity as biomarkers of response of renal cell carcinoma (RCC) to treatment with sunitinib. Journal of clinical oncology, Vol.29 (15).

Leary, A., Pickering, L.M., Larkin, J.M., Leach, M.O., Gore, M.E., Sohaib, A., Collins, D.J. & Koh, D. (2011). Quantitative diffusion-weighted (DW) MR imaging of microcapillary perfusion and tissue diffusivity as biomarkers of response of renal cell carcinoma (RCC) to treatment with sunitinib. J clin oncol, Vol.29 (15_suppl), p. TPS154.  show abstract

Ertas, G., Doran, S. & Leach, M.O. (2011). Computerized detection of breast lesions in multi-centre and multi-instrument DCE-MR data using 3D principal component maps and template matching. Phys med biol, Vol.56 (24), pp. 7795-7811.  show abstract

Jamin, Y., Smyth, L., Robinson, S.P., Poon, E.S., Eykyn, T.R., Springer, C.J., Leach, M.O. & Payne, G.S. (2011). Noninvasive detection of carboxypeptidase G2 activity in vivo. Nmr biomed, Vol.24, pp. 343-350.  show abstract

Al-Saffar, N.M., Jackson, L.E., Raynaud, F.I., Clarke, P.A., Ramírez de Molina, A., Lacal, J.C., Workman, P. & Leach, M.O. (2010). The phosphoinositide 3-kinase inhibitor PI-103 downregulates choline kinase alpha leading to phosphocholine and total choline decrease detected by magnetic resonance spectroscopy. Cancer res, Vol.70 (13), pp. 5507-5517.  show abstract

Beloueche-Babari, M., Chung, Y.-., Al-Saffar, N.M., Falck-Miniotis, M. & Leach, M.O. (2010). Metabolic assessment of the action of targeted cancer therapeutics using magnetic resonance spectroscopy. Br j cancer, Vol.102 (1), pp. 1-7.  show abstract

Beloueche-Babari, M., Arunan, V., Jackson, L.E., Perusinghe, N., Sharp, S.Y., Workman, P. & Leach, M.O. (2010). Modulation of melanoma cell phospholipid metabolism in response to heat shock protein 90 inhibition. Oncotarget, Vol.1 (3), pp. 185-197.  show abstract

Arias-Mendoxa, F., Howe, F., Griffiths, J.R., Glickson, J.D., O'Connor, O., Koutcher, J.A., Leach, M.O., Heerschap, A., Brown, T.R. & Applications, C.G., et al. (2010). Correlation of the intra-tumor phospholipid-related signatures determined noninvasively by phosphorus and hydrogen MR spectroscopy: An approach to increase the sensitivity and applicability of the technique to predict therapeutic outcome in non-Hodgkin's lymphoma. Journal of clinical oncology, Vol.28 (15).

Leach, M.O. (2009). Breast cancer screening in women at high risk using MRI. Nmr biomed, Vol.22 (1), pp. 17-27.  show abstract

Lee, C.P., Payne, G.S., Oregioni, A., Ruddle, R., Tan, S., Raynaud, F.I., Eaton, D., Campbell, M.J., Cross, K., Halbert, G., et al. (2009). A phase I study of the nitroimidazole hypoxia marker SR4554 using 19F magnetic resonance spectroscopy. Br j cancer, Vol.101 (11), pp. 1860-1868.  show abstract

Newbold, K., Castellano, I., Charles-Edwards, E., Mears, D., Sohaib, A., Leach, M., Rhys-Evans, P., Clarke, P., Fisher, C., Harrington, K., et al. (2009). AN EXPLORATORY STUDY INTO THE ROLE OF DYNAMIC CONTRAST-ENHANCED MAGNETIC RESONANCE IMAGING OR PERFUSION COMPUTED TOMOGRAPHY FOR DETECTION OF INTRATUMORAL HYPOXIA IN HEAD-AND-NECK CANCER. Int j radiat oncol, Vol.74 (1), pp. 29-37.  show abstract

Koh, , Blackledge, M., Collins, D.J., Padhani, A.R., Wallace, T., Wilton, B., Taylor, N.J., Stirling, J.J., Sinha, R., Walicke, P., et al. (2009). Reproducibility and changes in the apparent diffusion coefficients of solid tumours treated with combretastatin A4 phosphate and bevacizumab in a two-centre phase I clinical trial. European radiology, Vol.19 (11), pp. 2728-2738.

Jackson, A.S., Reinsberg, S.A., Sohaib, S.A., Charles-Edwards, E.M., Jhavar, S., Christmas, T.J., Thompson, A.C., Bailey, M.J., Corbishley, C.M., Fisher, C., et al. (2009). Dynamic contrast-enhanced MRI for prostate cancer localization. Br j radiol, Vol.82 (974), pp. 148-156.  show abstract

Gabellieri, C., Beloueche-Babari, M., Jamin, Y., Payne, G.S., Leach, M.O. & Eykyn, T.R. (2009). Modulation of choline kinase activity in human cancer cells observed by dynamic 31P NMR. Nmr biomed, Vol.22 (4), pp. 456-461.  show abstract

Gabellieri, C., Leach, M.O. & Eykyn, T.R. (2009). Modulating the relaxivity of hyperpolarized substrates with gadolinium contrast agents. Contrast media mol imaging, Vol.4 (3), pp. 143-147.  show abstract

Beloueche-Babari, M., Peak, J.C., Jackson, L.E., Tiet, M.-., Leach, M.O. & Eccles, S.A. (2009). Changes in choline metabolism as potential biomarkers of phospholipase C{gamma}1 inhibition in human prostate cancer cells. Mol cancer ther, Vol.8 (5), pp. 1305-1311.  show abstract

Mancini, L., Davies, L., Friedlos, F., Falck-Miniotis, M., Dzik-Jurasz, A.S., Springer, C.J., Leach, M.O. & Payne, G.S. (2009). A novel technique to monitor carboxypeptidase G2 expression in suicide gene therapy using 19F magnetic resonance spectroscopy. Nmr biomed, Vol.22 (5), pp. 561-566.  show abstract

Orton, M.R., Miyazaki, K., Koh, D.-., Collins, D.J., Hawkes, D.J., Atkinson, D. & Leach, M.O. (2009). Optimizing functional parameter accuracy for breath-hold DCE-MRI of liver tumours. Phys med biol, Vol.54 (7), pp. 2197-2215.  show abstract

Evans, D.G., Lennard, F., Pointon, L.J., Ramus, S.J., Gayther, S.A., Sodha, N., Kwan-Lim, G.E., Leach, M.O., Warren, R., Thompson, D., et al. (2009). Eligibility for Magnetic Resonance Imaging Screening in the United Kingdom: Effect of Strict Selection Criteria and Anonymous DNA Testing on Breast Cancer Incidence in the MARIBS Study. Cancer epidem biomar, Vol.18 (7), pp. 2123-2131.  show abstract

Gilbert, F.J., Warren, R.M., Kwan-Lim, G., Thompson, D.J., Eeles, R.A., Evans, D.G., Leach, M.O. & United Kingdom Magnetic Resonance Imaging in Breast Screening (MARIBS) Study Group, (2009). Cancers in BRCA1 and BRCA2 carriers and in women at high risk for breast cancer: MR imaging and mammographic features. Radiology, Vol.252 (2), pp. 358-368.  show abstract

White, M.J., Hawkes, D.J., Melbourne, A., Collins, D.J., Coolens, C., Hawkins, M., Leach, M.O. & Atkinson, D. (2009). Motion Artifact Correction in Free-Breathing Abdominal MRI Using Overlapping Partial Samples to Recover Image Deformations. Magn reson med, Vol.62 (2), pp. 440-449.  show abstract

Kaffanke, J.B., Stocker, T., Romanzetti, S., Dierkes, T., Leach, M.O. & Shah, N.J. (2009). Phase-cycled averaging for the suppression of residual magnetisation in SPI sequences. J magn reson, Vol.199 (2), pp. 117-125.  show abstract

Waldman, A.D., Jackson, A., Price, S.J., Clark, C.A., Booth, T.C., Auer, D.P., Tofts, P.S., Collins, D.J., Leach, M.O., Rees, J.H., et al. (2009). Quantitative imaging biomarkers in neuro-oncology. Nat rev clin oncol, Vol.6 (8), pp. 445-454.  show abstract

Jamin, Y., Gabellieri, C., Smyth, L., Reynolds, S., Robinson, S.P., Springer, C.J., Leach, M.O., Payne, G.S. & Eykyn, T.R. (2009). Hyperpolarized (13)C magnetic resonance detection of carboxypeptidase G2 activity. Magn reson med, Vol.62 (5), pp. 1300-1304.  show abstract

Koh, D.M., Blackledge, M., Collins, D.J., Padhani, A.R., Wallace, T., Wilton, B., Taylor, N.J., Stirling, J.J., Sinha, R., Walicke, P., et al. (2009). Reproducibility and changes in the apparent diffusion coefficients of solid tumours treated with combretastatin A4 phosphate and bevacizumab in a two-centre phase I clinical trial. Eur radiol, Vol.19 (11), pp. 2728-2738.  show abstract

Arias-Mendoza, F., Leach, M.O., Koutcher, J.A., Griffiths, J.R., Heerschap, A., Glickson, J.D., O'Connor, O.A., Brown, T.R. & Cooperative Group for MR Applications in Cancer, (2009). Prediction of treatment response in subtypes of non-Hodgkin's lymphoma by in vivo (31)P MR spectroscopy before treatment. J clin oncol, Vol.27 (15_suppl), p. 8565.  show abstract

Thompson, D.J., Leach, M.O., Kwan-Lim, G., Gayther, S.A., Ramus, S.J., Warsi, I., Lennard, F., Khazen, M., Bryant, E., Reed, S., et al. (2009). Assessing the usefulness of a novel MRI-based breast density estimation algorithm in a cohort of women at high genetic risk of breast cancer: the UK MARIBS study. Breast cancer res, Vol.11 (6), p. R80.  show abstract

Chung, Y.L., Troy, H., Kristeleit, R., Aherne, W., Jackson, E., Atadja, P., Griffiths, J.R., Judson, I.R., Workman, P., Leach, M.O., et al. (2008). Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of a novel histone deacetylase inhibitor, LAQ824, in human colon carcinoma cells and xenografts. Neoplasia, Vol.10 (4), pp. 303-313.  show abstract

Koh, D.M., Brown, G., Riddell, A.M., Scurr, E., Collins, D.J., Allen, S.D., Chau, I., Cunningham, D., Desouza, N.M., Leach, M.O., et al. (2008). Detection of colorectal hepatic metastases using MnDPDP MR imaging and diffusion-weighted imaging (DWI) alone and in combination. Eur radiol, Vol.18 (5), pp. 903-910.  show abstract

Orton, M.R., d'Arcy, J.A., Walker-Samuel, S., Hawkes, D.J., Atkinson, D., Collins, D.J. & Leach, M.O. (2008). Computationally efficient vascular input function models for quantitative kinetic modelling using DCE-MRI. Phys med biol, Vol.53 (5), pp. 1225-1239.  show abstract

Miyazaki, K., Collins, D.J., Walker-Samuel, S., Taylor, J.N., Padhani, A.R., Leach, M.O. & Koh, D.-. (2008). Quantitative mapping of hepatic perfusion index using MR imaging: a potential reproducible tool for assessing tumour response to treatment with the antiangiogenic compound BIBF 1120, a potent triple angiokinase inhibitor. Eur radiol, Vol.18 (7), pp. 1414-1421.  show abstract

Gabellieri, C., Reynolds, S., Lavie, A., Payne, G.S., Leach, M.O. & Eykyn, T.R. (2008). Therapeutic target metabolism observed using hyperpolarized 15N choline. J am chem soc, Vol.130 (14), pp. 4598-4599.  show abstract

Khazen, M., Warren, R.M., Boggis, C.R., Bryant, E.C., Reed, S., Warsi, I., Pointon, L.J., Kwan-Lim, G.E., Thompson, D., Eeles, R., et al. (2008). A pilot study of compositional analysis of the breast and estimation of breast mammographic density using three-dimensional T-1-weighted magnetic resonance imaging. Cancer epidem biomar, Vol.17 (9), pp. 2268-2274.  show abstract

Peet, A.C., Arvanitis, T.N., Auer, D.P., Davies, N.P., Hargrave, D., Howe, F.A., Jaspan, T., Leach, M.O., Macarthur, D., MacPherson, L., et al. (2008). The value of magnetic resonance spectroscopy in tumour imaging. Arch dis child, Vol.93 (9), pp. 725-727.

White, M.J., O'Gorman, R.L., Charles-Edwards, E.M., Kane, P.A., Karani, J.B., Leach, M.O. & Totman, J.J. (2007). Parametric mapping of the hepatic perfusion index with gadolinium-enhanced volumetric MRI. Br j radiol, Vol.80 (950), pp. 113-120.  show abstract

White, M.J., O'Gorman, R.L., Charles-Edwards, E.M., Kane, P.A., Karani, J.B., Leach, M.O. & Totman, J.J. (2007). Parametric mapping of the hepatic perfusion index with gadolinium-enhanced volumetric MRI. Brit j radiol, Vol.80 (950), pp. 113-120.  show abstract

Saslow, D., Boetes, C., Burke, W., Harms, S., Leach, M.O., Lehman, C.D., Morris, E., Pisano, E., Schnall, M., Sener, S., et al. (2007). American Cancer Society guidelines for breast screening with MRI as an adjunct to mammography. Ca-cancer j clin, Vol.57 (2), pp. 75-89.  show abstract

Hutton, J., Walker, L.G., Sharp, D.M., Leach, M.O. & MRC study advisory grp, (2007). Magnetic resonance imaging: An acceptable way of screening women with a family history of breast cancer?. Psycho-oncol, Vol.16 (3), pp. 265-265.

Lankester, K.J., Taylor, J.N., Stirling, J.J., Boxall, J., d'Arcy, J.A., Collins, D.J., Walker-Samuel, S., Leach, M.O., Rustin, G.J. & Padhani, A.R., et al. (2007). Dynamic MRI for imaging tumor microvasculature: Comparison of susceptibility and relaxivity techniques in pelvic tumors. J magn reson imaging, Vol.25 (4), pp. 796-805.  show abstract

Koh, D.M., Scurr, E., Collins, D., Kanber, B., Norman, A., Leach, M.O. & Husband, J.E. (2007). Predicting response of colorectal hepatic metastasis: Value of pretreatment apparent diffusion coefficients. Am j roentgenol, Vol.188 (4), pp. 1001-1008.  show abstract

Tanner, C., Schnabel, J.A., Hill, D.L., Hawkes, D.J., Degenhard, A., Leach, M.O., Hose, D.R., Hall-Craggs, M.A. & Usiskin, S.I. (2007). Quantitative evaluation of free-form deformation registration for dynamic contrast-enhanced MR mammography. Med phys, Vol.34 (4), pp. 1221-1233.  show abstract

Riches, S.F., Collins, D.J., Scuffham, J.W. & Leach, M.O. (2007). EU Directive 2004/40: field measurements of a 1 5 T clinical MR scanner. Brit j radiol, Vol.80 (954), pp. 483-487.  show abstract

Walker-Samuel, S., Parker, C.C., Leach, M.O. & Collins, D.J. (2007). Reproducibility of reference tissue quantification of dynamic contrast-enhanced data: comparison with a fixed vascular input function. Phys med biol, Vol.52 (1), pp. 75-89.  show abstract

Walker-Samuel, S., Leach, M.O. & Collins, D.J. (2007). Reference tissue quantification of DCE-MRI data without a contrast agent calibration. Phys med biol, Vol.52 (3), pp. 589-601.  show abstract

Orton, M.R., Collins, D.J., Walker-Samuel, S., d'Arcy, J.A., Hawkes, D.J., Atkinson, D. & Leach, M.O. (2007). Bayesian estimation of pharmacokinetic parameters for DCE-MRI with a robust treatment of enhancement onset time. Phys med biol, Vol.52 (9), pp. 2393-2408.  show abstract

Melbourne, A., Atkinson, D., White, M.J., Collins, D., Leach, M. & Hawkes, D. (2007). Registration of dynamic contrast-enhanced MRI using a progressive principal component registration (PPCR). Phys med biol, Vol.52 (17), pp. 5147-5156.  show abstract

Gabellieri, C., Eykyn, T.R. & Leach, M.O. (2007). Conformational exchange in pimonidazole--a hypoxia marker. Magn reson chem, Vol.45 (8), pp. 621-623.  show abstract

Riches, S.F., Collins, D.J., Charles-Edwards, G.D., Shafford, J.C., Cole, J., Keevil, S.F. & Leach, M.O. (2007). Measurements of occupational exposure to switched gradient and spatially-varying magnetic fields in areas adjacent to 1 5 T clinical MRI systems. J magn reson imaging, Vol.26 (5), pp. 1346-1352.  show abstract

Jackson, A.S., Reinsberg, S.A., Sohaib, S.A., Charles-Edwards, E.M., Mangar, S.A., South, C.P., Leach, M.O. & Dearnaley, D.P. (2007). Distortion-corrected T2 weighted MRI: a novel approach to prostate radiotherapy planning. Br j radiol, Vol.80 (959), pp. 926-933.  show abstract

Tilanus-Linthorst, M.M., Obdeijn, I.M., Hop, W.C., Causer, P.A., Leach, M.O., Warner, E., Pointon, L., Hill, K., Klijn, J.G., Warren, R.M., et al. (2007). BRCA1 mutation and young age predict fast breast cancer growth in the Dutch, United Kingdom, and Canadian magnetic resonance imaging screening trials. Clin cancer res, Vol.13 (24), pp. 7357-7362.  show abstract

Eykyn, T.R. & Leach, M.O. (2007). Selective homonuclear Hartmann-Hahn for C-13 -> C-13 polarization transfer in solution state NMR. Mol phys, Vol.105 (13-14), pp. 1827-1832.  show abstract

Lessmann, B., Nattkemper, T.W., Kessar, P., Pointon, L., Khazen, M., Leach, M.O. & Degenhard, A. (2007). Multiscale analysis of MR-mammography. Z med phys, Vol.17 (3), pp. 166-171.  show abstract

Al-Saffar, N.M., Troy, H., Ramírez de Molina, A., Jackson, L.E., Madhu, B., Griffiths, J.R., Leach, M.O., Workman, P., Lacal, J.C., Judson, I.R., et al. (2006). Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma models. Cancer res, Vol.66 (1), pp. 427-434.  show abstract

Beloueche-Babari, M., Jackson, L.E., Al-Saffar, N.M., Eccles, S.A., Raynaud, F.I., Workman, P., Leach, M.O. & Ronen, S.M. (2006). Identification of magnetic resonance detectable metabolic changes associated with inhibition of phosphoinositide 3-kinase signaling in human breast cancer cells. Mol cancer ther, Vol.5 (1), pp. 187-196.  show abstract

Kaffanke, J., Dierkes, T., Romanzetti, S., Halse, M., Rioux, J., Leach, M.O., Balcom, B. & Shah, N.J. (2006). Application of the chirp z-transform to MRI data. J magn reson, Vol.178 (1), pp. 121-128.  show abstract

d'Arcy, J.A., Collins, D.J., Padhani, A.R., Walker-Samuel, S., Suckling, J. & Leach, M.O. (2006). Informatics in Radiology (infoRAD): Magnetic Resonance Imaging Workbench: analysis and visualization of dynamic contrast-enhanced MR imaging data. Radiographics, Vol.26 (2), pp. 621-632.  show abstract

Workman, P., Aboagye, E.O., Chung, Y.-., Griffiths, J.R., Hart, R., Leach, M.O., Maxwell, R.J., McSheehy, P.M., Price, P.M., Zweit, J., et al. (2006). Minimally invasive pharmacokinetic and pharmacodynamic technologies in hypothesis-testing clinical trials of innovative therapies. J natl cancer inst, Vol.98 (9), pp. 580-598.  show abstract

Padhani, A.R., Hayes, C., Assersohn, L., Powles, T., Makris, A., Suckling, J., Leach, M.O. & Husband, J.E. (2006). Prediction of clinicopathologic response of breast cancer to primary chemotherapy at contrast-enhanced MR imaging: initial clinical results. Radiology, Vol.239 (2), pp. 361-374.  show abstract

Tanner, C., Schnabel, J.A., Hill, D.L., Hawkes, D.J., Leach, M.O. & Hose, D.R. (2006). Factors influencing the accuracy of biomechanical breast models. Med phys, Vol.33 (6), pp. 1758-1769.  show abstract

Warren, R.M., Thompson, D., Pointon, L.J., Hoff, R., Gilbert, F.J., Padhani, A.R., Easton, D.F., Lakhani, S.R. & Leach, M.O. (2006). Evaluation of a prospective scoring system designed for a multicenter breast MR imaging screening study. Radiology, Vol.239 (3), pp. 677-685.  show abstract

Arias-Mendoza, F., Payne, G.S., Zakian, K.L., Schwarz, A.J., Stubbs, M., Stoyanova, R., Ballon, D., Howe, F.A., Koutcher, J.A., Leach, M.O., et al. (2006). In vivo31P MR spectral patterns and reproducibility in cancer patients studied in a multi-institutional trial. Nmr in biomedicine, Vol.19 (4), pp. 504-512.

Leach, M.O. (2006). Magnetic resonance spectroscopy (MRS) in the investigation of cancer at The Royal Marsden Hospital and The Institute of Cancer Research. Phys med biol, Vol.51 (13), pp. R61-R82.  show abstract

Partridge, M., Trapp, J.V., Adams, E.J., Leach, M.O., Webb, S. & Seco, J. (2006). An investigation of dose calculation accuracy in intensity-modulated radiotherapy of sites in the head & neck. Phys medica, Vol.22 (3), pp. 97-104.  show abstract

Payne, G.S., Troy, H., Vaidya, S.J., Griffiths, J.R., Leach, M.O. & Chung, Y.-. (2006). Evaluation of 31P high-resolution magic angle spinning of intact tissue samples. Nmr biomed, Vol.19 (5), pp. 593-598.  show abstract

Payne, G.S. & Leach, M.O. (2006). Applications of magnetic resonance spectroscopy in radiotherapy treatment planning. Br j radiol, Vol.79 Spec No 1, pp. S16-S26.  show abstract

Warren, R., Hayes, C., Pointon, L., Hoff, R., Gilbert, F.J., Padhani, A.R., Rubin, C., Kaplan, G., Raza, K., Wilkinson, L., et al. (2006). A test of performance of breast MRI interpretation in a multicentre screening study. Magn reson imaging, Vol.24 (7), pp. 917-929.  show abstract

Koh, D.M., Scurr, E., Collins, D.J., Pirgon, A., Kanber, B., Karanjia, N., Brown, G., Leach, M.O. & Husband, J.E. (2006). Colorectal hepatic metastases: quantitative measurements using single-shot echo-planar diffusion-weighted MR imaging. Eur radiol, Vol.16 (9), pp. 1898-1905.  show abstract

Griebsch, I., Brown, J., Boggis, C., Dixon, A., Dixon, M., Easton, D., Eeles, R., Evans, D.G., Gilbert, F.J., Hawnaur, J., et al. (2006). Cost-effectiveness of screening with contrast enhanced magnetic resonance imaging vs X-ray mammography of women at a high familial risk of breast cancer. Brit j cancer, Vol.95 (7), pp. 801-810.  show abstract

Beloueche-Babari, M., Jackson, L.E., Workman, P. & Leach, M.O. (2006). Inhibition of MEK1/2 signalling with CI-1040 in human melanoma cells leads to alterations in phosphocholine metabolism. Ejc suppl, Vol.4 (12), pp. 170-171.

Walker-Samuel, S., Leach, M.O. & Collins, D.J. (2006). Evaluation of response to treatment using DCE-MRI: the relationship between initial area under the gadolinium curve (IAUGC) and quantitative pharmacokinetic analysis. Phys med biol, Vol.51 (14), pp. 3593-3602.  show abstract

Payne, G.S., Collins, D.J., Loynds, P., Mould, G., Murphy, P.S., Dzik-Jurasz, A.S., Kessar, P., Haque, N., Yamaguchi, M., Atarashi, S., et al. (2005). Quantitative assessment of the hepatic pharmacokinetics of the antimicrobial sitafloxacin in humans using in vivoF magnetic resonance spectroscopy. Br j clin pharmacol, Vol.59 (2), pp. 244-248.  show abstract

Peet, A.C., Leach, M.O., Pinkerton, C.R., Price, P., Williams, S.R. & Grundy, R.G. (2005). Proceedings of the Engineering and Physical Sciences Research Council Workshop - The development of functional imaging in the diagnosis, management and understanding of childhood brain tumours. Pediatr blood cancer, Vol.44 (2), pp. 103-113.  show abstract

McSheehy, P.M., Port, R.E., Rodrigues, L.M., Robinson, S.P., Stubbs, M., van der Borns, K., Peters, G.J., Judson, I.R., Leach, M.O. & Griffiths, J.R., et al. (2005). Investigations in vivo of the effects of carbogen breathing on 5-fluorouracil pharmacokinetics and physiology of solid rodent tumours. Cancer chemoth pharm, Vol.55 (2), pp. 117-128.  show abstract

Oregioni, A., Eykyn, T.R., Hosny, N., Payne, G.S. & Leach, M.O. (2005). Adiabatic half-passage pulses for measuring the polarization of highly non-equilibrium spin-systems. Chem phys lett, Vol.414 (1-3), pp. 102-106.  show abstract

Jhavar, S.G., Fisher, C., Jackson, A., Reinsberg, S.A., Dennis, N., Falconer, A., Dearnaley, D., Edwards, S.E., Edwards, S.M., Leach, M.O., et al. (2005). Processing of radical prostatectomy specimens for correlation of data from histopathological, molecular biological, and radiological studies: a new whole organ technique. J clin pathol, Vol.58 (5), pp. 504-508.  show abstract

Padhani, A.R. & Leach, M.O. (2005). Antivascular cancer treatments: functional assessments by dynamic contrast-enhanced magnetic resonance imaging. Abdom imaging, Vol.30 (3), pp. 324-341.  show abstract

Doran, S.J., Bourgeois, M.E. & Leach, M.O. (2005). Burst imaging - Can it ever be useful in the clinic?. Concept magn reson a, Vol.26A (1), pp. 11-34.  show abstract

Nattkemper, T.W., Arnrich, B., Lichte, O., Timm, W., Degenhard, A., Pointon, L., Hayes, C. & Leach, M.O. (2005). Evaluation of radiological features for breast tumour classification in clinical screening with machine learning methods. Artif intell med, Vol.34 (2), pp. 129-139.  show abstract

Doran, S.J., Charles-Edwards, L., Reinsberg, S.A. & Leach, M.O. (2005). A complete distortion correction for MR images: I Gradient warp correction. Phys med biol, Vol.50 (7), pp. 1343-1361.  show abstract

Zaitsev, M., D'Arcy, J., Collins, D.J., Leach, M.O., Zilles, K. & Shah, N.J. (2005). Dual-contrast echo planar imaging with keyhole: application to dynamic contrast-enhanced perfusion studies. Phys med biol, Vol.50 (19), pp. 4491-4505.  show abstract

Reinsberg, S.A., Doran, S.J., Charles-Edwards, E.M. & Leach, M.O. (2005). A complete distortion correction for MR images: II Rectification of static-field inhomogeneities by similarity-based profile mapping. Phys med biol, Vol.50 (11), pp. 2651-2661.  show abstract

Leach, M.O., Brindle, K.M., Evelhoch, J.L., Griffiths, J.R., Horsman, M.R., Jackson, A., Jayson, G.C., Judson, I.R., Knopp, M.V., Maxwell, R.J., et al. (2005). The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations. Br j cancer, Vol.92 (9), pp. 1599-1610.  show abstract

Trapp, J.V., Leach, M.O. & Webb, S. (2005). Preliminary dose response study of a gel dosimeter using 2-Hydroxyethyl Methacrylate (HEMA). Australas phys eng sci med, Vol.28 (3), pp. 172-174.  show abstract

Warren, R.M., Pointon, L., Thompson, D., Hoff, R., Gilbert, F.J., Padhani, A., Easton, D., Lakhani, S.R., Leach, M.O. & MARIBS Study Grp, , et al. (2005). Reading protocol for dynamic contrast-enhanced MR images of the breast: Sensitivity and specificity analysis. Radiology, Vol.236 (3), pp. 779-788.  show abstract

Payne, G.S., Dzik-Jurasz, A.S., Mancini, L., Nutley, B., Raynaud, F. & Leach, M.O. (2005). Identification of biliary metabolites of ifosfamide using 31P magnetic resonance spectroscopy and mass spectrometry. Cancer chemother pharmacol, Vol.56 (4), pp. 409-414.  show abstract

Prescot, A.P., Dzik-Jurasz, A.S., Leach, M.O., Sirohi, B., Powles, R. & Collins, D.J. (2005). Localized COSY and DQF-COSY 1H-MRS sequences for investigating human tibial bone marrow in vivo and initial application to patients with acute leukemia. J magn reson imaging, Vol.22 (4), pp. 541-548.  show abstract

van As, N., Jackson, A., Sohaib, S., South, C., Charles-Edwards, E., Reinsberg, S., Leach, M. & Dearnaley, D. (2005). Prostate and pelvis radiotherapy using IMRT and ultra small superparamagnetic nano-particles to optimise dose to involved lymph nodes. Ejc suppl, Vol.3 (2), pp. 399-400.

Jackson, A., Sohaib, S., South, C., Reinsberg, S., Charles-Edwards, L., Leach, M. & Dearnaley, D. (2005). Distortion corrected T2 weighted MRI: implications for rectal and bladder dose sparing in prostate radiotherapy planning. Ejc suppl, Vol.3 (2), pp. 410-410.

Mancini, L., Payne, G.S. & Leach, M.O. (2005). Implementation and evaluation of CSI-localized J cross-polarization for detection of 31P magnetic resonance spectra in vivo. Magn reson med, Vol.54 (5), pp. 1065-1071.  show abstract

Keevil, S.F., Gedroyc, W., Gowland, P., Hill, D.L., Leach, M.O., Ludman, C.N., McLeish, K., McRobbie, D.W., Razavi, R.S. & Young, I.R., et al. (2005). Electromagnetic field exposure limitation and the future of MRI. Brit j radiol, Vol.78 (935), pp. 973-975.

Beloueche-Babari, M., Jackson, L.E., Al-Saffar, N.M., Workman, P., Leach, M.O. & Ronen, S.M. (2005). Magnetic resonance spectroscopy monitoring of mitogen-activated protein kinase signaling inhibition. Cancer res, Vol.65 (8), pp. 3356-3363.  show abstract

O'Donnell, A., Padhani, A., Hayes, C., Kakkar, A.J., Leach, M., Trigo, J.M., Scurr, M., Raynaud, F., Phillips, S., Aherne, W., et al. (2005). A phase I study of the angiogenesis inhibitor SU5416 (semaxanib) in solid tumours, incorporating dynamic contrast MR pharmacodynamic end points. Brit j cancer, Vol.93 (8), pp. 876-883.  show abstract

Leach, M.O., Boggis, C.R., Dixon, A.K., Easton, D.F., Eeles, R.A., Evans, D.G., Gilbert, F.J., Griebsch, I., Hoff, R.J., Kessar, P., et al. (2005). Screening with magnetic resonance imaging and mammography of a UK population at high familial risk of breast cancer: a prospective multicentre cohort study (MARIBS). Lancet, Vol.365 (9473), pp. 1769-1778.  show abstract

Eykyn, T.R., Payne, G.S. & Leach, M.O. (2005). Inversion recovery measurements in the presence of radiation damping and implications for evaluating contrast agents in magnetic resonance. Phys med biol, Vol.50 (22), pp. N371-N376.  show abstract

Lankester, K.J., Taylor, N.J., Stirling, J.J., Boxall, J., D'Arcy, J.A., Leach, M.O., Rustin, G.J. & Padhani, A.R. (2005). Effects of platinum/taxane based chemotherapy on acute perfusion in human pelvic tumours measured by dynamic MRI. Brit j cancer, Vol.93 (9), pp. 979-985.  show abstract

Chung, Y.L., Troy, H., Judson, I.R., Leek, R., Leach, M.O., Stubbs, M., Harris, A.L. & Griffiths, J.R. (2004). Noninvasive measurements of capecitabine metabolism in bladder tumors overexpressing thymidine phosphorylase by fluorine-19 magnetic resonance spectroscopy. Clin cancer res, Vol.10 (11), pp. 3863-3870.  show abstract

Charles-Edwards, G.D., Payne, G.S., Leach, M.O. & Bifone, A. (2004). Effects of residual single-quantum coherences in intermolecular multiple-quantum coherence studies. J magn reson, Vol.166 (2), pp. 215-227.  show abstract

Ah-See, M.W., Padhani, A.R., Taylor, N.J., Daley, F.M., Bentzen, S.M., Burcombe, R.J., Harrison, M., Stirling, J.J., Leach, M.O. & Makris, A., et al. (2004). Evaluation of VEGF expression within breast cancer biopsies & tumour microvasculature assessment by multi-functional dynamic contrast-enhanced MRI. European journal of cancer supplements, Vol.2 (3), pp. 100-100.

Trapp, J.V., Partridge, M., Hansen, V.N., Childs, P., Bedford, J., Warrington, A.P., Leach, M.O. & Webb, S. (2004). The use of gel dosimetry for verification of electron and photon treatment plans in carcinoma of the scalp. Phys med biol, Vol.49 (9), pp. 1625-1635.  show abstract

Trapp, J.V., Warrington, A.P., Partridge, M., Philps, A., Glees, J., Tait, D., Ahmed, R., Leach, M.O. & Webb, S. (2004). Measurement of the three-dimensional distribution of radiation dose in grid therapy. Phys med biol, Vol.49 (19), pp. N317-N323.  show abstract

Dzik-Jurasz, A.S., Leach, M.O. & Rowland, I.J. (2004). Investigation of microenvironmental factors influencing the longitudinal relaxation times of drugs and other compounds. Magn reson imaging, Vol.22 (7), pp. 973-982.  show abstract

Arias-Mendoza, F., Zakian, K., Schwartz, A., Howe, F.A., Koutcher, J.A., Leach, M.O., Griffiths, J.R., Heerschap, A., Glickson, J.D., Nelson, S.J., et al. (2004). Methodological standardization for a multi-institutional in vivo trial of localized P-31 MR spectroscopy in human cancer research In vitro and normal volunteer studies. Nmr biomed, Vol.17 (6), pp. 382-391.  show abstract

(2004). Notices of Duplicate Publication. Radiology, Vol.233 (3), pp. 938-938.

Ah-See, M.W., Makris, A., Taylor, N.J., Burcombe, R.J., Harrison, M., Stirling, J.J., Richman, P.I., Leach, M.O. & Padhani, A.R. (2004). Does vascular imaging with MRI predict response to neoadjuvant chemotherapy in primary breast cancer?. J clin oncol, Vol.22 (14_suppl), p. 582.  show abstract

Trapp, J.V., Michael, G., Evans, P.M., Baldock, C., Leach, M.O. & Webb, S. (2004). Dose resolution in gel dosimetry: effect of uncertainty in the calibration function. Phys med biol, Vol.49 (10), pp. N139-N146.  show abstract

Delakis, I., Moore, E.M., Leach, M.O. & De Wilde, J.P. (2004). Developing a quality control protocol for diffusion imaging on a clinical MRI system. Phys med biol, Vol.49 (8), pp. 1409-1422.  show abstract

Fragoso, M., Love, P.A., Verhaegen, F., Nalder, C., Bidmead, A.M., Leach, M. & Webb, S. (2004). The dose distribution of low dose rate Cs-137 in intracavitary brachytherapy: comparison of Monte Carlo simulation, treatment planning calculation and polymer gel measurement. Phys med biol, Vol.49 (24), pp. 5459-5474.  show abstract

Murphy, P.S., Viviers, L., Abson, C., Rowland, I.J., Brada, M., Leach, M.O. & Dzik-Jurasz, A.S. (2004). Monitoring temozolomide treatment of low-grade glioma with proton magnetic resonance spectroscopy. Br j cancer, Vol.90 (4), pp. 781-786.  show abstract

Leach, M.O., Brindl, K.M., Evelhoch, J.L., Griffiths, J.R., Horsman, M.R., Jackson, A., Hayson, G., Judson, I.R., Knopp, M.V., Maxwell, R.J., et al. (2004). Assessment of antiangiogenic and antivascular therapeutics using MRI: Recommendations for appropriate methodology for clinical trials. Br j radiol, Vol.76, pp. S87-S91.

Seddon, B.M., Payne, G.S., Simmons, L., Ruddle, R., Grimshaw, R., Tan, S., Turner, A., Raynaud, F., Halbert, G., Leach, M.O., et al. (2003). A phase I study of SR-4554 via intravenous administration for noninvasive investigation of tumor hypoxia by magnetic resonance spectroscopy in patients with malignancy. Clin cancer res, Vol.9 (14), pp. 5101-5112.  show abstract

Lee, Y.K., Bollet, M., Charles-Edwards, G., Flower, M.A., Leach, M.O., McNair, H., Moore, E., Rowbottom, C. & Webb, S. (2003). Radiotherapy treatment planning of prostate cancer using magnetic resonance imaging alone. Radiother oncol, Vol.66 (2), pp. 203-216.  show abstract

Schnabel, J.A., Tanner, C., Castellano-Smith, A.D., Degenhard, A., Leach, M.O., Hose, D.R., Hill, D.L. & Hawkes, D.J. (2003). Validation of nonrigid image registration using finite-element methods: Application to breast MR images. Ieee t med imaging, Vol.22 (2), pp. 238-247.  show abstract

McSheehy, P.M., Troy, H., Kelland, L.R., Judson, I.R., Leach, M.O. & Griffiths, J.R. (2003). Increased tumour extracellular pH induced by Bafilomycin A1 inhibits tumour growth and mitosis in vivo and alters 5-fluorouracil pharmacokinetics. Eur j cancer, Vol.39 (4), pp. 532-540.  show abstract

Vaidya, S.J., Payne, G.S., Leach, M.O. & Pinkerton, C.R. (2003). Potential role of magnetic resonance spectroscopy in assessment of tumour response in childhood cancer. Eur j cancer, Vol.39 (6), pp. 728-735.  show abstract

Chung, Y.-., Troy, H., Banerji, U., Jackson, L.E., Walton, M.I., Stubbs, M., Griffiths, J.R., Judson, I.R., Leach, M.O., Workman, P., et al. (2003). Magnetic resonance spectroscopic pharmacodynamic markers of the heat shock protein 90 inhibitor 17-allylamino,17-demethoxygeldanamycin (17AAG) in human colon cancer models. J natl cancer inst, Vol.95 (21), pp. 1624-1633.  show abstract

Murphy, P.S., Rowland, I.J., Viviers, L., Brada, M., Leach, M.O. & Dzik-Jurasz, A.S. (2003). Could assessment of glioma methylene lipid resonance by in vivo (1)H-MRS be of clinical value?. Br j radiol, Vol.76 (907), pp. 459-463.  show abstract

Ong, J.T., d'Arcy, J.A., Collins, D.J., Rivens, I.H., ter Haar, G.R. & Leach, M.O. (2003). Sliding window dual gradient echo (SW-dGRE): T1 and proton resonance frequency (PRF) calibration for temperature imaging in polyacrylamide gel. Phys med biol, Vol.48 (13), pp. 1917-1931.  show abstract

Dzik-Jurasz, A.S., Prescot, A.P., Leach, M. & Collins, D.J. (2003). Non-invasive study of human gall bladder bile in vivo using H-1-MR spectroscopy. Brit j radiol, Vol.76 (907), pp. 483-486.  show abstract

Mancini, L., Payne, G.S., Dzik-Jurasz, A.S. & Leach, M.O. (2003). Ifosfamide pharmacokinetics and hepatobiliary uptake in vivo investigated using single- and double-resonance P-31 MRS. Magnet reson med, Vol.50 (2), pp. 249-255.  show abstract

Mancini, L., Payne, G.S. & Leach, M.O. (2003). Comparison of polarization transfer sequences for enhancement of signals in clinical 31P MRS studies. Magn reson med, Vol.50 (3), pp. 578-588.  show abstract

Prescot, A.P., Collins, D.J., Leach, M.O. & Dzik-Jurasz, A.S. (2003). Human gallbladder bile: noninvasive investigation in vivo with single-voxel 1H MR spectroscopy. Radiology, Vol.229 (2), pp. 587-592.  show abstract

Cherubini, A., Payne, G.S., Leach, M.O. & Bifone, A. (2003). Hyperpolarising C-13 for NMR studies using laser-polarised Xe-129: SPINOE vs thermal mixing. Chem phys lett, Vol.371 (5-6), pp. 640-644.  show abstract

Love, P.A., Evans, P.M., Leach, M.O. & Webb, S. (2003). Polymer gel measurement of dose homogeneity in the breast: comparing MLC intensity modulation with standard wedged delivery. Phys med biol, Vol.48 (8), pp. 1065-1074.  show abstract

Leach, M.O., Brindle, K.M., Evelhoch, J.L., Griffiths, J.R., Horsman, M.R., Jackson, A., Jayson, G., Judson, I.R., Knopp, M.V., Maxwell, R.J., et al. (2003). Assessment of antiangiogenic and antivascular therapeutics using MRI: recommendations for appropriate methodology for clinical trials. Brit j radiol, Vol.76, pp. S87-S91.

Murphy, P.S., Dzik-Jurasz, A.S., Leach, M.O. & Rowland, I.J. (2002). The effect of Gd-DTPA on T(1)-weighted choline signal in human brain tumours. Magn reson imaging, Vol.20 (1), pp. 127-130.  show abstract

Wolber, J., Cherubini, A., Leach, M.O. & Bifone, A. (2002). Hyperpolarized Xe-129 NMR as a probe for blood oxygenation. Magnet reson med, Vol.43, pp. 491-496.

Padhani, A.R., Hayes, C., Landau, S. & Leach, M.O. (2002). Reproducibility of quantitative dynamic MRI of normal human tissues. Nmr biomed, Vol.15 (2), pp. 143-153.  show abstract

d'Arcy, J.A., Collins, D.J., Rowland, I.J., Padhani, A.R. & Leach, M.O. (2002). Applications of sliding window reconstruction with cartesian sampling for dynamic contrast enhanced MRI. Nmr biomed, Vol.15 (2), pp. 174-183.  show abstract

Dzik-Jurasz, A.S., Murphy, P.S., George, M., Prock, T., Collins, D.J., Swift, I., Leach, M.O. & Rowland, I.J. (2002). Human rectal adenocarcinoma: demonstration of 1H-MR spectra in vivo at 1 5 T. Magn reson med, Vol.47 (4), pp. 809-811.  show abstract

Hayes, C., Padhani, A.R. & Leach, M.O. (2002). Assessing changes in tumour vascular function using dynamic contrast-enhanced magnetic resonance imaging. Nmr biomed, Vol.15 (2), pp. 154-163.  show abstract

Lankester, K.J., Taylor, N.J., Stirling, J.J., Boxall, J., Rustin, G.J., Leach, M.O., Maxwell, R.J. & Padhani, A.R. (2002). Dynamic contrast enhanced MRI assessment of acute microvascular effects with conventional cytotoxic chemotherapy in human tumours. Brit j cancer, Vol.86, pp. S99-S99.

Leach, M.O. (2002). Assessing response to treatment in breast cancer using magnetic resonance. J exp clin cancer res, Vol.21 (3 Suppl), pp. 39-45.  show abstract

Leach, M.O., Eeles, R.A., Turnbull, L.W., Dixon, A.K., Brown, J., Hoff, R.J., Coulthard, A., Dixon, J.M., Easton, D.F., Evans, D.G., et al. (2002). The UK national study of magnetic resonance imaging as a method of screening for breast cancer (MARIBS). J exp clin cancer res, Vol.21 (3 Suppl), pp. 107-114.  show abstract

Warren, R.M., Pointon, L., Caines, R., Hayes, C., Thompson, D., Leach, M.O. & UK MRI breast screening study, (2002). What is the recall rate of breast MRI when used for screening asymptomatic women at high risk?. Magn reson imaging, Vol.20 (7), pp. 557-565.  show abstract

Degenhard, A., Tanner, C., Hayes, C., Hawkes, D.J., Leach, M.O. & UK MRI Breast Screening Study, (2002). Comparison between radiological and artificial neural network diagnosis in clinical screening. Physiol meas, Vol.23 (4), pp. 727-739.  show abstract

Schwarz, A.J., Maisey, N.R., Collins, D.J., Cunningham, D., Huddart, R. & Leach, M.O. (2002). Early in vivo detection of metabolic response: a pilot study of 1H MR spectroscopy in extracranial lymphoma and germ cell tumours. Br j radiol, Vol.75 (900), pp. 959-966.  show abstract

Al-Saffar, N.M., Titley, J.C., Robertson, D., Clarke, P.A., Jackson, L.E., Leach, M.O. & Ronen, S.M. (2002). Apoptosis is associated with triacyglycerol accumulation in Jurkat T-cells. Brit j cancer, Vol.86 (6), pp. 963-970.  show abstract

Prock, T., Collins, D.J., Dzik-Jurasz, A.S. & Leach, M.O. (2002). An algorithm for the optimum combination of data from arbitrary magnetic resonance phased array probes. Phys med biol, Vol.47 (2), pp. N39-N46.  show abstract

Murphy, P.S., Leach, M.O. & Rowland, I.J. (2002). The effects of paramagnetic contrast agents on metabolite protons in aqueous solution. Phys med biol, Vol.47 (6), pp. N53-N59.  show abstract

Degenhard, A., Hayes, C. & Leach, M.O. (2002). Consecutive projections onto convex sets. Phys med biol, Vol.47 (6), pp. N61-N66.  show abstract

Prock, T., Collins, D.J. & Leach, M.O. (2002). A model to assess SAR for surface coil magnetic resonance spectroscopy measurements. Phys med biol, Vol.47 (10), pp. 1805-1817.  show abstract

Estilaei, M.R., Matson, G.B., Payne, G.S., Leach, M.O., Fein, G. & Meyerhoff, D.J. (2001). Effects of chronic alcohol consumption on the broad phospholipid signal in human brain: An in vivo P-31 MRS study. Alcohol clin exp res, Vol.25 (1), pp. 89-97.  show abstract

Padhani, A.R., MacVicar, A.D., Gapinski, C.J., Dearnaley, D.P., Parker, G.J., Suckling, J., Leach, M.O. & Husband, J.E. (2001). Effects of androgen deprivation on prostatic morphology and vascular permeability evaluated with mr imaging. Radiology, Vol.218 (2), pp. 365-374.  show abstract

Ronen, S.M., Jackson, L.E., Beloueche, M. & Leach, M.O. (2001). Magnetic resonance detects changes in phosphocholine associated with Ras activation and inhibition in NIH 3T3 cells. Br j cancer, Vol.84 (5), pp. 691-696.  show abstract

George, M.L., Dzik-Jurasz, A.S., Brown, G., Padhani, A.R., Husband, J., Leach, M.O., Rowland, I.J., Hill, M.E., Cunningham, D.C., Tait, D., et al. (2001). Dynamic contrast MRI (DCMRI) assessment of tumour permeability in locally advanced rectal cancer: a prognostic indicator for response to chemoradiotherapy. Brit j surg, Vol.88, pp. 25-25.

Klomp, D.W., Collins, D.J., van den Boogert, H.J., Schwarz, A., Rijpkema, M., Prock, T., Payne, G.S., Leach, M.O. & Heerschap, A. (2001). Radio-frequency probe for H-1 decoupled P-31 MRS of the head and neck region. Magn reson imaging, Vol.19 (5), pp. 755-759.  show abstract

Prock, T., Collins, D.J. & Leach, M.O. (2001). Numerical evaluation of shaped surface coil sensitivity at 63 MHz. Phys med biol, Vol.46 (7), pp. 1753-1765.  show abstract

Dzik-Jurasz, A.S., Wolber, J., Prock, T., Collins, D.J., Leach, M.O. & Rowland, I.J. (2001). The quantitative F-19-imaging of albumin at 1 5 T: a potential in-vivo tool. Magn reson imaging, Vol.19 (6), pp. 839-844.  show abstract

Degenhard, A., Tanner, C., Hayes, C., Hawkes, D.J. & Leach, M.O. (2001). Pre-processed image reconstruction applied to breast and brain MR imaging. Physiol meas, Vol.22 (3), pp. 589-604.  show abstract

Estilaei, M.R., Matson, G.B., Payne, G.S., Leach, M.O., Fein, G. & Meyerhoff, D.J. (2001). Effects of abstinence from alcohol on the broad phospholipid signal in human brain: An in vivo P-31 magnetic resonance spectroscopy study. Alcohol clin exp res, Vol.25 (8), pp. 1213-1220.  show abstract

Wolber, J., McIntyre, D.J., Rodrigues, L.M., Carnochan, P., Griffiths, J.R., Leach, M.O. & Bifone, A. (2001). In vivo hyperpolarized 129Xe NMR spectroscopy in tumors. Magn reson med, Vol.46 (3), pp. 586-591.  show abstract

Seddon, B., Simmons, L., Grimshaw, R., Tan, S., Raynaud, F., Judson, I., Workman, P., Payne, G. & Leach, M. (2001). Phase I pharmacokinetic and spectroscopic study of SR 4554: A new nitroimidazole used as a non-invasive probe of tumor hypoxia detected by F-19 magnetic resonance spectroscopy. Clin cancer res, Vol.7 (11), pp. 3700S-3700S.

Anderson, H., Price, P., Blomley, M., Leach, M.O., Workman, P. & Canc Res Campaign PK PD Technolog, (2001). Measuring changes in human tumour vasculature in response to therapy using functional imaging techniques. Brit j cancer, Vol.85 (8), pp. 1085-1093.  show abstract

Ronen, S.M. & Leach, M.O. (2001). Imaging biochemistry: applications to breast cancer. Breast cancer res, Vol.3 (1), pp. 36-40.  show abstract

Leach, M.O. (2001). Application of magnetic resonance imaging to angiogenesis in breast cancer. Breast cancer res, Vol.3 (1), pp. 22-27.  show abstract

Padhani, A.R., Gapinski, C.J., Macvicar, D.A., Parker, G.J., Suckling, J., Revell, P.B., Leach, M.O., Dearnaley, D.P. & Husband, J.E. (2000). Dynamic contrast enhanced MRI of prostate cancer: correlation with morphology and tumour stage, histological grade and PSA. Clin radiol, Vol.55 (2), pp. 99-109.  show abstract

Parker, G.J., Baustert, I., Tanner, S.F. & Leach, M.O. (2000). Improving image quality and T(1) measurements using saturation recovery turboFLASH with an approximate K-space normalisation filter. Magn reson imaging, Vol.18 (2), pp. 157-167.  show abstract

Denbow, M.L., Rivens, I.H., Rowland, I.J., Leach, M.O., Fisk, N.M. & ter Haar, G.R. (2000). Preclinical development of noninvasive vascular occlusion with focused ultrasonic surgery for fetal therapy. Am j obstet gynecol, Vol.182 (2), pp. 387-392.  show abstract

Wolber, J., Cherubini, A., Leach, M.O. & Bifone, A. (2000). Hyperpolarized 129Xe NMR as a probe for blood oxygenation. Magn reson med, Vol.43 (4), pp. 491-496.  show abstract

Payne, G.S. & Leach, M.O. (2000). Surface-coil polarization transfer for monitoring tissue metabolism in vivo. Magn reson med, Vol.43 (4), pp. 510-516.  show abstract

Murphy, P.S., Cosgrove, V.P., Schwarz, A.J., Webb, S. & Leach, M.O. (2000). Proton spectroscopic imaging of polyacrylamide gel dosimeters for absolute radiation dosimetry. Phys med biol, Vol.45 (4), pp. 835-845.  show abstract

Baustert, I.C., Oldham, M., Smith, T.A., Hayes, C., Webb, S. & Leach, M.O. (2000). Optimized MR imaging for polyacrylamide gel dosimetry. Phys med biol, Vol.45 (4), pp. 847-858.  show abstract

Brown, J., Coulthard, A., Dixon, A.K., Dixon, J.M., Easton, D.F., Eeles, R.A., Evans, D.G., Gilbert, F.G., Hayes, C., Jenkins, J.P., et al. (2000). Rationale for a national multi-centre study of magnetic resonance imaging screening in women at genetic risk of breast cancer. Breast, Vol.9 (2), pp. 72-77.  show abstract

Brown, J., Coulthard, A., Dixon, A.K., Dixon, J.M., Easton, D.F., Eeles, R.A., Evans, D.G., Gilbert, F.G., Hayes, C., Jenkins, J.P., et al. (2000). Protocol for a national multi-centre study of magnetic resonance imaging screening in women at genetic risk of breast cancer. Breast, Vol.9 (2), pp. 78-82.  show abstract

Davidson, A., Tait, D.M., Payne, G.S., Hopewell, J.W., Leach, M.O., Watson, M., MacVicar, A.D., Britton, J.A. & Ashley, S. (2000). Magnetic resonance spectroscopy in the evaluation of neurotoxicity following cranial irradiation for childhood cancer. Brit j radiol, Vol.73 (868), pp. 421-424.  show abstract

Cosgrove, V.P., Murphy, P.S., McJury, M., Adams, E.J., Warrington, A.P., Leach, M.O. & Webb, S. (2000). The reproducibility of polyacrylamide gel dosimetry applied to stereotactic conformal radiotherapy. Phys med biol, Vol.45 (5), pp. 1195-1210.  show abstract

Smith, T.A., Maisey, N., Titley, J.C., Jackson, L.E., Leach, M.O. & Ronen, S.M. (2000). Changes in deoxyglucose uptake is associated with glucose transport modification in tumor cell response to therapy. J nucl med, Vol.41 (5), pp. 263P-263P.

Hoogenraad, F.G., Pouwels, P.J., Hofman, M.B., Rombouts, S.A., Lavini, C., Leach, M.O. & Haacke, E.M. (2000). High-resolution segmented EPI in a motor task fMRI study. Magnetic resonance imaging, Vol.18 (4), pp. 405-409.

Wolber, J., Cherubini, A., Leach, M.O. & Bifone, A. (2000). On the oxygenation-dependent (129)Xe T (1) in blood. Nmr biomed, Vol.13 (4), pp. 234-237.  show abstract

Lavini, C., Payne, G.S., Leach, M.O. & Bifone, A. (2000). Intravenous delivery of hyperpolarized (129)Xe: a compartmental model. Nmr biomed, Vol.13 (4), pp. 238-244.  show abstract

Wolber, J., Cherubini, A., Leach, M.O. & Bifone, A. (2000). On the oxygenation-dependent Xe-129 T-1 in blood. Nmr biomed, Vol.13 (4), pp. 234-237.  show abstract

Li, B.S., Payne, G.S., Collins, D.J. & Leach, M.O. (2000). 1H decoupling for in vivo (19)F MRS studies using the time-share modulation method on a clinical 1 5 T NMR system. Magn reson med, Vol.44 (1), pp. 5-9.  show abstract

George, M.L., Dzik-Jurasz, A.S., Padhani, A., Leach, M.O., Rowland, I.J., Eccles, S.A. & Swift, R.I. (2000). Comparison of vascular permeability measured by dynamic MRI and serum/plasma VEGF in locally advanced rectal cancer. Brit j cancer, Vol.83, pp. 20-20.

Davidson, A., Payne, G., Leach, M.O., McVicar, D., Britton, J.M., Watson, M. & Tait, D.M. (2000). Proton magnetic resonance spectroscopy ((1)H-MRS) of the brain following high-dose methotrexate treatment for childhood cancer. Med pediatr oncol, Vol.35 (1), pp. 28-34.  show abstract

Schwarz, A.J. & Leach, M.O. (2000). Implications of respiratory motion for the quantification of 2D MR spectroscopic imaging data in the abdomen. Phys med biol, Vol.45 (8), pp. 2105-2116.  show abstract

Tanner, S.F., Finnigan, D.J., Khoo, V.S., Mayles, P., Dearnaley, D.P. & Leach, M.O. (2000). Radiotherapy planning of the pelvis using distortion corrected MR images: the removal of system distortions. Phys med biol, Vol.45 (8), pp. 2117-2132.  show abstract

Payne, G.S., Pinkerton, C.R., Bouffet, E. & Leach, M.O. (2000). Initial measurements of ifosfamide and cyclophosphamide in patients using P-31 MRS: Pulse-and-acquire, decoupling, and polarization transfer. Magnet reson med, Vol.44 (2), pp. 180-184.  show abstract

McJury, M., Oldham, M., Cosgrove, V.P., Murphy, P.S., Doran, S., Leach, M.O. & Webb, S. (2000). Radiation dosimetry using polymer gels: methods and applications. Br j radiol, Vol.73 (873), pp. 919-929.  show abstract

Brown, J., Buckley, D., Coulthard, A., Dixon, A.K., Dixon, J.M., Easton, D.F., Eeles, R.A., Evans, D.G., Gilbert, F.G., Graves, M., et al. (2000). Magnetic resonance imaging screening in women at genetic risk of breast cancer: imaging and analysis protocol for the UK multicentre study. Magn reson imaging, Vol.18 (7), pp. 765-776.  show abstract

Brown, J., Buckley, D., Coulthard, A., Dixon, A.K., Dixon, J.M., Easton, D.F., Eeles, R.A., Evans, D.G., Gilbert, F.G., Graves, M., et al. (2000). Magnetic resonance imaging screening in women at genetic risk of breast cancer: imaging and analysis protocol for the UK multicentre study UK MRI Breast Screening Study Advisory Group. Magnetic resonance imaging, Vol.18 (7), pp. 765-776.  show abstract

Smith, T.A., Maisey, N.R., Titley, J.C., Jackson, L.E., Leach, M.O. & Ronen, S.M. (2000). Treatment of SW620 cells with Tomudex and oxaliplatin induces changes in 2-deoxy-D-glucose incorporation associated with modifications in glucose transport. J nucl med, Vol.41 (10), pp. 1753-1759.  show abstract

Dzik-Jurasz, A.S., Collins, D.J., Leach, M.O. & Rowland, I.J. (2000). Gallbladder localization of F-19 MRS catabolite signals in patients receiving bolus and protracted venous infusional 5-fluorouracil. Magnet reson med, Vol.44 (4), pp. 516-520.  show abstract

Schwarz, A.J., Rijpkema, M., Collins, D.J., Payne, G.S., Prock, T., Woodward, A.C., Heerschap, A. & Leach, M.O. (2000). SAR and tissue heating with a clinical (31)P MRS protocol using surface coils, adiabatic pulses, and proton-decoupling. Magn reson med, Vol.44 (5), pp. 692-700.  show abstract

Murphy, P.S., Cosgrove, V.P., Leach, M.O. & Webb, S. (2000). A modified polymer gel for radiotherapy dosimetry: assessment by MRI and MRS. Phys med biol, Vol.45 (11), pp. 3213-3223.  show abstract

Troy, H., McSheehy, P.M., Judson, I.R., Workman, P., Leach, M.O. & Griffiths, J.R. (2000). Early detection of the response of human HT29 adenocarcinomas to the thioredoxin inhibitor, PX12, using P-31-magnetic resonance spectroscopy (MRS) in vivo. Clin cancer res, Vol.6, pp. 4563S-4563S.

McSheehy, P., Troy, H., Leach, M.O., Judson, I.R. & Griffiths, J.R. (2000). Mouse hepatomas deficient in Hypoxia-inducible-Factor-1 beta (HIF-1 beta) show increased metabolism of 2 '-fluoro-2 '-deoxy-D-glucose (FDG) compared to wildtype. Clin cancer res, Vol.6, pp. 4563S-4564S.

McSheehy, P.M., Leach, M.O., Judson, I.R. & Griffiths, J.R. (2000). Metabolites of 2 '-fluoro-2 '-deoxy-D-glucose detected by F-19 magnetic resonance spectroscopy in vivo predict response of murine RIF-1 tumors to 5-fluorouracil. Cancer res, Vol.60 (8), pp. 2122-2127.  show abstract

Padhani, A.R., Khoo, V.S., Suckling, J., Husband, J.E., Leach, M.O. & Dearnaley, D.P. (1999). Evaluating the effect of rectal distension and rectal movement on prostate gland position using cine MRI. Int j radiat oncol biol phys, Vol.44 (3), pp. 525-533.  show abstract

Wolber, J., Rowland, I.J., Leach, M.O. & Bifone, A. (1999). Perfluorocarbon emulsions as intravenous delivery media for hyperpolarized xenon. Magn reson med, Vol.41 (3), pp. 442-449.  show abstract

Rivens, I.H., Rowland, I.J., Denbow, M., Fisk, N.M., ter Haar, G.R. & Leach, M.O. (1999). Vascular occlusion using focused ultrasound surgery for use in fetal medicine. Eur j ultrasound, Vol.9 (1), pp. 89-97.  show abstract

Ronen, S.M., DiStefano, F., McCoy, C.L., Robertson, D., Smith, T.A., Al-Saffar, N.M., Titley, J., Cunningham, D.C., Griffiths, J.R., Leach, M.O., et al. (1999). Magnetic resonance detects metabolic changes associated with chemotherapy-induced apoptosis. Br j cancer, Vol.80 (7), pp. 1035-1041.  show abstract

Khoo, V.S., Padhani, A.R., Tanner, S.F., Finnigan, D.J., Leach, M.O. & Dearnaley, D.P. (1999). Comparison of MRI with CT for the radiotherapy planning of prostate cancer: a feasibility study. Br j radiol, Vol.72 (858), pp. 590-597.  show abstract

Maisey, N.R., Smith, T.A., Ronen, S.M. & Leach, M.O. (1999). Do early changes in deoxy-glucose uptake vary with therapy?. Brit j cancer, Vol.80, pp. 108-108.

Maisey, N.R., Hill, M.E., Webb, A., Cunningham, D., Flux, G.D., Padhani, A., Ott, R.J. & Norman, A. (1999). Can PET avoid the need for radiotherapy in lymphoma residual masses?. British journal of cancer, Vol.80, pp. 108-108.

McJury, M., Oldham, M., Leach, M.O. & Webb, S. (1999). Dynamics of polymerization in polyacrylamide gel (PAG) dosimeters: (I) ageing and long-term stability. Phys med biol, Vol.44 (8), pp. 1863-1873.  show abstract

Rueckert, D., Sonoda, L.I., Hayes, C., Hill, D.L., Leach, M.O. & Hawkes, D.J. (1999). Nonrigid registration using free-form deformations: Application to breast MR images. Ieee t med imaging, Vol.18 (8), pp. 712-721.  show abstract

Hepworth, S.J., Leach, M.O. & Doran, S.J. (1999). Dynamics of polymerization in polyacrylamide gel (PAG) dosimeters: (II) modelling oxygen diffusion. Phys med biol, Vol.44 (8), pp. 1875-1884.  show abstract

Denton, E.R., Sonoda, L.I., Rueckert, D., Rankin, S.C., Hayes, C., Leach, M.O., Hill, D.L. & Hawkes, D.J. (1999). Comparison and evaluation of rigid, affine, and nonrigid registration of breast MR images. J comput assist tomo, Vol.23 (5), pp. 800-805.  show abstract

McJury, M., Tapper, P.D., Cosgrove, V.P., Murphy, P.S., Griffin, S., Leach, M.O., Webb, S. & Oldham, M. (1999). Experimental 3D dosimetry around a high-dose-rate clinical 192Ir source using a polyacrylamide gel (PAG) dosimeter. Phys med biol, Vol.44 (10), pp. 2431-2444.  show abstract

Payne, G.S., Pinkerton, C.R. & Leach, M.O. (1999). Magnetic resonance spectroscopy studies of ifosfamide in vivo. Clin cancer res, Vol.5, pp. 3827S-3827S.

Padhani, A., Hayes, C., Judson, I., Workman, P., Langecker, P., Leach, M. & Husband, J. (1999). Dynamic contrast enhanced MR imaging in the evaluation of antiangiogenesis therapy. Clin cancer res, Vol.5, pp. 3828S-3828S.

Murphy, P.S., Leach, M.O. & Rowland, I.J. (1999). Signal modulation in (1)H magnetic resonance spectroscopy using contrast agents: proton relaxivities of choline, creatine, and N-acetylaspartate. Magn reson med, Vol.42 (6), pp. 1155-1158.  show abstract

Ojugo, A.S., McSheehy, P.M., McIntyre, D.J., McCoy, C., Stubbs, M., Leach, M.O., Judson, I.R. & Griffiths, J.R. (1999). Measurement of the extracellular pH of solid tumours in mice by magnetic resonance spectroscopy: a comparison of exogenous F-19 and P-31 probes. Nmr biomed, Vol.12 (8), pp. 495-504.  show abstract

Liney, G.P., Gibbs, P., Hayes, C., Leach, M.O. & Turnbull, L.W. (1999). Dynamic contrast‐enhanced MRI in the differentiation of breast tumors: User‐defined versus semi‐automated region‐of‐interest analysis. Journal of magnetic resonance imaging, Vol.10 (6), pp. 945-949.

Wolber, J., Cherubini, A., Dzik-Jurasz, A.S., Leach, M.O. & Bifone, A. (1999). Spin-lattice relaxation of laser-polarized xenon in human blood. Proc natl acad sci u s a, Vol.96 (7), pp. 3664-3669.  show abstract

Khoo, V.S., Padhani, A.R., Suckling, J., Husband, J.E., Leach, M.O. & Dearnaley, D.P. (1998). The effect of rectal activity on prostate gland position during cine MRI of the pelvis: Implications for radiotherapy planning. Brit j cancer, Vol.78, pp. 8-8.

Parker, G.J., Suckling, J., Tanner, S.F., Padhani, A.R., Husband, J.E. & Leach, M.O. (1998). MRIW: parametric analysis software for contrast-enhanced dynamic MR imaging in cancer. Radiographics, Vol.18 (2), pp. 497-506.  show abstract

Ojugo, A.S., McSheehy, P.M., Stubbs, M., Alder, G., Bashford, C.L., Maxwell, R.J., Leach, M.O., Judson, I.R. & Griffiths, J.R. (1998). Influence of pH on the uptake of 5-fluorouracil into isolated tumour cells. Brit j cancer, Vol.77 (6), pp. 873-879.  show abstract

Oldham, M., Baustert, I., Lord, C., Smith, T.A., McJury, M., Warrington, A.P., Leach, M.O. & Webb, S. (1998). An investigation into the dosimetry of a nine-field tomotherapy irradiation using BANG-gel dosimetry. Phys med biol, Vol.43 (5), pp. 1113-1132.  show abstract

Wolber, J., Doran, S.J., Leach, M.O. & Bifone, A. (1998). Measuring diffusion of xenon in solution with hyperpolarized Xe-129 NMR. Chem phys lett, Vol.296 (3-4), pp. 391-396.  show abstract

Oldham, M., McJury, M., Baustert, I.B., Webb, S. & Leach, M.O. (1998). Improving calibration accuracy in gel dosimetry. Phys med biol, Vol.43 (10), pp. 2709-2720.  show abstract

Leach, M.O., Verrill, M., Glaholm, J., Smith, T.A., Collins, D.J., Payne, G.S., Sharp, J.C., Ronen, S.M., McCready, V.R., Powles, T.J., et al. (1998). Measurements of human breast cancer using magnetic resonance spectroscopy: a review of clinical measurements and a report of localized 31P measurements of response to treatment. Nmr biomed, Vol.11 (7), pp. 314-340.  show abstract

Bifone, A., Payne, G.S. & Leach, M.O. (1998). In vivo multiple spin echoes. J magn reson, Vol.135 (1), pp. 30-36.  show abstract

Keevil, S.F., Barbiroli, B., Brooks, J.C., Cady, E.B., Canese, R., Carlier, P., Collins, D.J., Gilligan, P., Gobbi, G., Hennig, J., et al. (1998). Absolute metabolite quantification by in vivo NMR spectroscopy: II a multicentre trial of protocols for in vivo localised proton studies of human brain. Magnetic resonance imaging, Vol.16 (9), pp. 1093-1106.

Podo, F., Henriksen, O., Bovée, W.M., Leach, M.O., Leibfritz, D. & de Certaines, J.D. (1998). Absolute metabolite quantification by in vivo NMR spectroscopy: I introduction, objectives and activities of a concerted action in biomedical research. Magnetic resonance imaging, Vol.16 (9), pp. 1085-1092.

Leach, M. (1998). Untitled. Physics in medicine and biology, Vol.43 (12), pp. U3-U3.

McSheehy, P.M., Robinson, S.P., Ojugo, A.S., Aboagye, E.O., Cannell, M.B., Leach, M.O., Judson, I.R. & Griffiths, J.R. (1998). Carbogen breathing increases 5-fluorouracil uptake and cytotoxicity in hypoxic murine RIF-1 tumors: A magnetic resonance study in vivo. Cancer res, Vol.58 (6), pp. 1185-1194.  show abstract

Taylor, N.J., Doyle, V.L., Fox, R.A. & Leach, M.O. (1998). A simple phantom to locate the origin of MRI ghost artefacts. Magn reson imaging, Vol.16 (1), pp. 73-76.  show abstract

Khoo, V.S., Dearnaley, D.P., Finnigan, D.J., Padhani, A., Tanner, S.F. & Leach, M.O. (1997). Magnetic resonance imaging (MRI): considerations and applications in radiotherapy treatment planning. Radiother oncol, Vol.42 (1), pp. 1-15.  show abstract

Rowland, I.J., Rivens, I., Chen, L., Lebozer, C.H., Collins, D.J., ter Haar, G.R. & Leach, M.O. (1997). MRI study of hepatic tumours following high intensity focused ultrasound surgery. Br j radiol, Vol.70, pp. 144-153.  show abstract

Doyle, V.L., Payne, G.S., Collins, D.J., Verrill, M.W. & Leach, M.O. (1997). Quantification of phosphorus metabolites in human calf muscle and soft-tissue tumours from localized MR spectra acquired using surface coils. Phys med biol, Vol.42 (4), pp. 691-706.  show abstract

Parker, G.J., Suckling, J., Tanner, S.F., Padhani, A.R., Revell, P.B., Husband, J.E. & Leach, M.O. (1997). Probing tumor microvascularity by measurement, analysis and display of contrast agent uptake kinetics. J magn reson imaging, Vol.7 (3), pp. 564-574.  show abstract

Payne, G.S. & Leach, M.O. (1997). Implementation and evaluation of frequency offset corrected inversion (FOCI) pulses on a clinical MR system. Magn reson med, Vol.38 (5), pp. 828-833.  show abstract

McSheehy, P.M., Seymour, M.T., Ojugo, A.S., Rodrigues, L.M., Leach, M.O., Judson, I.R. & Griffiths, J.R. (1997). A pharmacokinetic and pharmacodynamic study in vivo of human HT29 tumours using F-19 and P-31 magnetic resonance spectroscopy. Eur j cancer, Vol.33 (14), pp. 2418-2427.  show abstract

Findlay, M.P., Raynaud, F., Cunningham, D., Iveson, A., Collins, D.J. & Leach, M.O. (1996). Measurement of plasma 5-fluorouracil by high-performance liquid chromatography with comparison of results to tissue drug levels observed using in vivo 19F magnetic resonance spectroscopy in patients on a protracted venous infusion with or without interferon-alpha. Ann oncol, Vol.7 (1), pp. 47-53.  show abstract

Leach, M. (1996). Untitled. Physics in medicine and biology, Vol.41 (1), pp. U4-U4.

van Sluis, R., Yongbi, N.M., Payne, G.S. & Leach, M.O. (1996). Simultaneous localized 1H STEAM/31P ISIS spectroscopy in vivo. Magn reson med, Vol.35 (4), pp. 465-470.  show abstract

Leach, M.O. (1996). Introduction to in vivo MRS of cancer: new perspectives and open problems. Anticancer res, Vol.16 (3B), pp. 1503-1514.  show abstract

Tanner, S.F., Clarke, J., Leach, M.O., Mesbahi, M.H., Nicolson, V., Powles, R., Husband, J.E. & Tait, D. (1996). MRI in the evaluation of late bone marrow changes following bone marrow transplantation. Br j radiol, Vol.69 (828), pp. 1145-1151.  show abstract

Doyle, V.L., Buil, M., Payne, G.S. & Leach, M.O. (1995). Calculation of sensitivity correction factors for surface coil MRS. Magn reson med, Vol.33 (1), pp. 108-112.  show abstract

Keevil, S.F., Barbiroli, B., Collins, D.J., Danielsen, E.R., Hennig, J., Henriksen, O., Leach, M.O., Longo, R., Lowry, M., Moore, C., et al. (1995). Quality assessment in in vivo NMR spectroscopy: IV A multicentre trial of test objects and protocols for performance assessment in clinical NMR spectroscopy. Magnetic resonance imaging, Vol.13 (1), pp. 139-157.

Bovée, W.M., Keevil, S.F., Leach, M.O. & Podo, F. (1995). Quality assessment in in vivo NMR spectroscopy: II A protocol for quality assessment. Magnetic resonance imaging, Vol.13 (1), pp. 123-129.

Yongbi, N.M., Payne, G.S., Collins, D.J. & Leach, M.O. (1995). Quantification of signal selection efficiency, extra volume suppression and contamination for ISIS, STEAM and PRESS localized 1H NMR spectroscopy using an EEC localization test object. Phys med biol, Vol.40 (7), pp. 1293-1303.  show abstract

ARTEMOV, D., BHUJWALLA, Z., MAXWELL, R., GRIFFITHS, J., JUDSON, I., LEACH, M. & GLICKSON, J. (1995). PHARMACOKINETICS OF THE C-13 LABELED ANTICANCER AGENT TEMOZOLOMIDE DETECTED IN-VIVO BY SELECTIVE CROSS-POLARIZATION TRANSFER. Magnet reson med, Vol.34 (3), pp. 338-342.  show abstract

van Sluis, R., Payne, G.S. & Leach, M.O. (1995). Increased NOE enhancement in 1H decoupled 31P MRS. Magn reson med, Vol.34 (6), pp. 893-897.  show abstract

Payne, G.S. & Leach, M.O. (1995). On doubling the signal in localised stimulated echo measurements. Magn reson imaging, Vol.13 (4), pp. 629-632.  show abstract

Leach, M.O., Collins, D.J., Keevil, S., Rowland, I., Smith, M.A., Henriksen, O., Bovée, W.M. & Podo, F. (1995). Quality assessment in in vivo NMR spectroscopy: III Clinical test objects: design, construction, and solutions. Magn reson imaging, Vol.13 (1), pp. 131-137.  show abstract

SHARP, J. & LEACH, M. (1994). A PHASE-ENCODED SELECTION TECHNIQUE (PEST) FOR SLICE SELECTION WITHOUT RESONANT-FREQUENCY-OFFSET ERRORS. J magn reson ser b, Vol.103 (2), pp. 168-174.

Findlay, M.P. & Leach, M.O. (1994). In vivo monitoring of fluoropyrimidine metabolites: magnetic resonance spectroscopy in the evaluation of 5-fluorouracil. Anticancer drugs, Vol.5 (3), pp. 260-280.  show abstract

Leach, M.O., Arnold, D., Brown, T.R., Charles, H.C., de Certaines, J.D., Evelhoch, J.L., Margulis, A.R., Negendank, W.G., Nelson, S.J. & Podo, F., et al. (1994). International Workshop on Standardization in Clinical Magnetic Resonance Spectroscopy Measurements: proceedings and recommendations. Acad radiol, Vol.1 (2), pp. 171-186.

Leach, M.O., Arnold, D., Brown, T.R., Charles, H.C., de Certaines, J.D., Evelhoch, J.L., Margulis, A.R., Negendank, W.G., Nelson, S.J. & Podo, F., et al. (1994). International workshop on standardization in clinical MRS measurements: proceedings and recommendations. Technol health care, Vol.2 (4), pp. 217-234.

Leach, M.O. (1994). Magnetic resonance spectroscopy applied to clinical oncology. Technol health care, Vol.2 (4), pp. 235-246.  show abstract

Yongbi, N.M., Payne, G.S. & Leach, M.O. (1994). A gradient scheme suitable for localized shimming and in vivo 1H/31P STEAM and ISIS NMR spectroscopy. Magn reson med, Vol.32 (6), pp. 768-772.  show abstract

GOWLAND, P., LEACH, M. & TANNER, S. (1994). REDUCING MOTION ARTIFACTS IN IN-VIVO MAGNETIC-RESONANCE-IMAGING MEASUREMENTS OF RELAXATION-TIMES. Brit j radiol, Vol.67 (804), pp. 1249-1257.  show abstract

Gowland, P.A., Leach, M.O. & Tanner, S.F. (1994). Technical note: reducing motion artifacts in in vivo magnetic resonance imaging measurements of relaxation times. Br j radiol, Vol.67 (804), pp. 1249-1257.  show abstract

Smith, T.A., Baluch, S., Titley, J.C., Ormerod, M.G., Eccles, S., Tombs, A.J., Leach, M.O., Griffiths, J.R. & McCready, V.R. (1993). The effect of oestrogen ablation on the phospholipid metabolite content of primary and transplanted rat mammary tumours. Nmr biomed, Vol.6 (3), pp. 209-214.  show abstract

FINDLAY, M., LEACH, M., CUNNINGHAM, D., COLLINS, D., PAYNE, G., GLAHOLM, J., MANSI, J. & MCCREADY, V. (1993). THE NONINVASIVE MONITORING OF LOW-DOSE, INFUSIONAL 5-FLUOROURACIL AND ITS MODULATION BY INTERFERON-ALPHA USING IN-VIVO F-19 MAGNETIC-RESONANCE SPECTROSCOPY IN PATIENTS WITH COLORECTAL-CANCER - A PILOT-STUDY. Ann oncol, Vol.4 (7), pp. 597-602.  show abstract

SMITH, T., BUSH, C., JAMESON, C., TITLEY, J., LEACH, M., WILMAN, D. & MCCREADY, V. (1993). PHOSPHOLIPID METABOLITES, PROGNOSIS AND PROLIFERATION IN HUMAN BREAST-CARCINOMA. Nmr biomed, Vol.6 (5), pp. 318-323.  show abstract

Taylor, N.J., Rowland, I.J., Tanner, S.F. & Leach, M.O. (1993). A rapid interleaved method for measuring signal intensity curves in both blood and tissue during contrast agent administration. Magn reson med, Vol.30 (6), pp. 744-749.  show abstract

SHARP, J., LEACH, M. & COLLINS, D. (1992). A SINGLE-SHOT SHIMMING SEQUENCE USING LOW-POWER RF NOISE PULSES FOR LOCALIZED INVIVO NMR-SPECTROSCOPY. Phys med biol, Vol.37 (1), pp. 281-287.

Sharp, J.C. & Leach, M.O. (1992). Rapid localization of concave volumes by conformal NMR spectroscopy. Magn reson med, Vol.23 (2), pp. 386-393.  show abstract

Webb, S., Collins, D.J. & Leach, M.O. (1992). Quantitative magnetic resonance spectroscopy by optimized numerical curve fitting. Nmr biomed, Vol.5 (2), pp. 87-94.  show abstract

YONGBI, N., LEACH, M., PAYNE, G. & COLLINS, D. (1992). A 2-POINT VOLUME LOCALIZED T1 MEASUREMENT SEQUENCE FOR INVIVO SPECTROSCOPY USING A SURFACE COIL. Nmr biomed, Vol.5 (2), pp. 95-100.  show abstract

PAYNE, G. & LEACH, M. (1992). THRESHOLD VOLTAGES FOR HYPERBOLIC SECANT INVERSION PULSES. Nmr biomed, Vol.5 (3), pp. 142-144.  show abstract

GOWLAND, P. & LEACH, M. (1992). FAST AND ACCURATE MEASUREMENTS OF T(1) USING A MULTI-READOUT SINGLE INVERSION-RECOVERY SEQUENCE. Magnet reson med, Vol.26 (1), pp. 79-88.

Leach, M.O. (1992). Practicalities of localization in animal and human tumours. Nmr biomed, Vol.5 (5), pp. 244-252.  show abstract

Madden, A. & Leach, M.O. (1992). Radial diffusion coefficient mapping. Br j radiol, Vol.65 (778), pp. 885-894.  show abstract

Madden, A., Leach, M.O., Sharp, J.C., Collins, D.J. & Easton, D. (1991). A quantitative analysis of the accuracy of in vivo pH measurements with 31P NMR spectroscopy: assessment of pH measurement methodology. Nmr biomed, Vol.4 (1), pp. 1-11.  show abstract

Gowland, P.A. & Leach, M.O. (1991). A simple method for the restoration of signal polarity in multi-image inversion recovery sequences for measuring T1. Magn reson med, Vol.18 (1), pp. 224-231.  show abstract

SMITH, T., GLAHOLM, J., LEACH, M., MACHIN, L., COLLINS, D., PAYNE, G. & MCCREADY, V. (1991). A COMPARISON OF INVIVO AND INVITRO P-31 NMR-SPECTRA FROM HUMAN BREAST-TUMORS - VARIATIONS IN PHOSPHOLIPID-METABOLISM. Brit j cancer, Vol.63 (4), pp. 514-516.  show abstract

Madden, A., Leach, M.O., Collins, D.J. & Payne, G.S. (1991). The water resonance as an alternative pH reference: relevance to in vivo 31P NMR localized spectroscopy studies. Magn reson med, Vol.19 (2), pp. 416-421.  show abstract

Davies, S. & Leach, M. (1991). Globalism Versus Villagism: Food Security and Environmental National and International Levels. Ids bulletin, Vol.22 (3), pp. 43-50.

Davies, S. & Leach, M. (1991). Editorial. Ids bulletin, Vol.22 (3), pp. 1-4.

Mansi, J.L., de Graeff, A., Newell, D.R., Glaholm, J., Button, D., Leach, M.O., Payne, G. & Smith, I.E. (1991). A phase II clinical and pharmacokinetic study of Lonidamine in patients with advanced breast cancer. Br j cancer, Vol.64 (3), pp. 593-597.  show abstract

SMITH, T., ECCLES, S., ORMEROD, M., TOMBS, A., TITLEY, J. & LEACH, M. (1991). THE PHOSPHOCHOLINE AND GLYCEROPHOSPHOCHOLINE CONTENT OF AN ESTROGEN-SENSITIVE RAT MAMMARY-TUMOR CORRELATES STRONGLY WITH GROWTH-RATE. Brit j cancer, Vol.64 (5), pp. 821-826.  show abstract

SMITH, T., GLAHOLM, J., LEACH, M., MACHIN, L. & MCCREADY, V. (1991). THE EFFECT OF INTRA-TUMOR HETEROGENEITY ON THE DISTRIBUTION OF PHOSPHORUS-CONTAINING METABOLITES WITHIN HUMAN BREAST-TUMORS - AN INVITRO STUDY USING P-31 NMR-SPECTROSCOPY. Nmr biomed, Vol.4 (6), pp. 262-267.  show abstract

GLAHOLM, J., SHARP, J.C., COLLINS, D., ROWELL, N.P., LEACH, M.O., FARNSWORTH, K., MCCREADY, V.R. & HIND, A.J. (1990). INVIVO LOCALIZED P-31 SPECTROSCOPY OF HUMAN BREAST-CARCINOMA. Brit j cancer, Vol.61 (1), pp. 176-176.

Madden, A., Glaholm, J. & Leach, M.O. (1990). An assessment of the sensitivity of in vivo 31P nuclear magnetic resonance spectroscopy as a means of detecting pH heterogeneity in tumours: a simulation study. Br j radiol, Vol.63 (746), pp. 120-124.  show abstract

GLAHOLM, J., LEACH, M., COLLINS, D., ALJEHAZI, B., SHARP, J., SMITH, T., ADACH, J., HIND, A., MCCREADY, V. & WHITE, H., et al. (1990). COMPARISON OF 5-FLUOROURACIL PHARMACOKINETICS FOLLOWING INTRAPERITONEAL AND INTRAVENOUS ADMINISTRATION USING INVIVO F-19 MAGNETIC-RESONANCE SPECTROSCOPY. Brit j radiol, Vol.63 (751), pp. 547-553.

MADDEN, A., LEACH, M. & COLLINS, D. (1989). PH CALIBRATION CURVE AT 1 5 TESLA. Phys med biol, Vol.34 (9), pp. 1289-1293.

SHARP, J. & LEACH, M. (1989). CONFORMAL NMR-SPECTROSCOPY - ACCURATE LOCALIZATION TO NONCUBOIDAL VOLUMES WITH OPTIMUM SNR. Magnet reson med, Vol.11 (3), pp. 376-388.

GLAHOLM, J., LEACH, M., COLLINS, D., MANSI, J., SHARP, J., MADDEN, A., SMITH, I. & MCCREADY, V. (1989). INVIVO P-31 MAGNETIC-RESONANCE SPECTROSCOPY FOR MONITORING TREATMENT RESPONSE IN BREAST-CANCER. Lancet, Vol.1 (8650), pp. 1326-1327.

Madden, A. & Leach, M.O. (1989). Installation of an ambient-temperature control system in a 1 5-tesla whole body system to facilitate animal studies. Med phys, Vol.16 (6), pp. 916-919.  show abstract

GOWLAND, P., LEACH, M. & SHARP, J. (1989). THE USE OF AN IMPROVED INVERSION PULSE WITH THE SPIN-ECHO INVERSION-RECOVERY SEQUENCE TO GIVE INCREASED ACCURACY AND REDUCED IMAGING TIME FOR T1 MEASUREMENTS. Magnet reson med, Vol.12 (2), pp. 261-267.

MAUREEMOOTOO, K., WEBB, S., LEACH, M. & BENTLEY, R. (1988). THE PERFORMANCE-CHARACTERISTICS OF A SIMULATOR-BASED CT-SCANNER. Ieee t med imaging, Vol.7 (2), pp. 91-98.

LEACH, M. & COLLINS, D. (1988). THE ROLE OF NUCLEAR MAGNETIC-RESONANCE IMAGING IN RADIOTHERAPY. Brit j radiol, Vol.61 (726), pp. 560-560.

WEBB, S., LEACH, M., BENTLEY, R., MAUREEMOOTOO, K., NAHUM, A., TOMS, M., GARDINER, J., PARTON, D., UNWIN, S. & YARNOLD, J., et al. (1988). THE ROLE OF THE ROYAL-MARSDEN-HOSPITAL COMPUTED-TOMOGRAPHY SIMULATOR IN PLANNING RADIOTHERAPY TREATMENT FOR BREAST-CANCER. Brit j radiol, Vol.61 (726), pp. 562-562.

GLAHOLM, J., COLLINS, D., LEACH, M., MCCREADY, V., SHARP, J., FARNSWORTH, K. & ADACH, J. (1988). INVIVO F-19 NMR-SPECTROSCOPY - HUMAN 5-FLUOROURACIL PHARMACOKINETIC COMPARISON OF INTRAPERITONEAL VERSUS INTRAVENOUS DRUG ADMINISTRATION. Tumordiagn ther, Vol.9 (4), pp. 165-166.

MCCREADY, V.R., LEACH, M.O., ADACH, J., SHARP, J., COLLINS, D., FARNSWORTH, K., HIND, A., GRIFFITHS, J., POWLES, T., WHITE, H., et al. (1988). P-31 NUCLEAR MAGNETIC SPECTROSCOPIC MONITORING OF TUMOR RESPONSE TO THERAPY. Brit j radiol, Vol.61 (729), pp. 876-877.

FLOWER, M., OTT, R., WEBB, S., LEACH, M., MARSDEN, P., CLACK, R., KHAN, O., BATTY, V., MCCREADY, V. & BATEMAN, J., et al. (1988). CLINICAL-TRIALS OF THE PROTOTYPE RUTHERFORD-APPLETON-LABORATORY MWPC POSITRON CAMERA AT THE ROYAL-MARSDEN-HOSPITAL. Nucl instrum meth a, Vol.269 (2), pp. 350-353.

LEACH, M.O., HIND, A.J., SHARPE, J.C., SAUTER, R., REQUARDT, E. & WEBER, H. (1987). THE USE OF A HIGH-FIELD, WHOLE-BODY, NMR IMAGING AND SPECTROSCOPY SYSTEM IN THE STUDY OF ONCOLOGY. Phys med biol, Vol.32 (2), pp. 286-286.

OTT, R., BATTY, V., WEBB, S., FLOWER, M., LEACH, M., CLACK, R., MARSDEN, P., MCCREADY, V., BATEMAN, J., SHARMA, H., et al. (1987). MEASUREMENT OF RADIATION-DOSE TO THE THYROID USING POSITRON EMISSION TOMOGRAPHY. Brit j radiol, Vol.60 (711), pp. 245-251.

Webb, S., Leach, M.O., Bentley, R.E., Maureemootoo, K., Yarnold, J.R., Toms, M.A., Gardiner, J. & Parton, D. (1987). Clinical dosimetry for radiotherapy to the breast based on imaging with the prototype Royal Marsden Hospital CT simulator. Phys med biol, Vol.32 (7), pp. 835-845.  show abstract

LEACH, M., MCCREADY, V., HIND, A., SHARP, J. & COLLINS, D. (1987). PIMSS - A CORRECTION FOR MUSCLE CONTAMINATION IN P-31 NUCLEAR-MAGNETIC-RESONANCE SPECTROSCOPY USING PROTON IMAGES AND A PHOSPHORUS SENSITIVITY IMAGE. Brit j radiol, Vol.60 (716), pp. 787-787.

LEACH, M., HIND, A. & GOWLAND, P. (1987). THE VARIATION OF SIGNAL, CONTRAST AND CONTRAST-TO-NOISE RATIO IN NUCLEAR-MAGNETIC-RESONANCE FAST IMAGING SEQUENCES. Brit j radiol, Vol.60 (716), pp. 788-788.

OTT, R., BATEMAN, J., BATTY, V., CLACK, R., FLOWER, M., LEACH, M., MARSDEN, P., MCCREADY, V., WEBB, S., SHARMA, H., et al. (1986). 3D POSITRON EMISSION TOMOGRAPHY - PRELIMINARY-RESULTS. Brit j radiol, Vol.59 (700), pp. 419-422.

LEACH, M., HIND, A., SAUTER, R., REQUARDT, H. & WEBER, H. (1986). THE DESIGN AND USE OF A DUAL-FREQUENCY SURFACE COIL PROVIDING PROTON IMAGES FOR IMPROVED LOCALIZATION IN P-31 SPECTROSCOPY OF SMALL LESIONS. Med phys, Vol.13 (4), pp. 510-513.

WEBB, S., OTT, R., FLOWER, M., LEACH, M., MARSDEN, P., BRODERICK, M., MCCREADY, V., LONG, A., CLACK, R. & BATEMAN, E., et al. (1986). PROGRESS TOWARDS THE MEASUREMENT OF THYROID VOLUME USING SPECT AND PET. Brit j radiol, Vol.59 (703), pp. 728-729.

LEACH, M. (1986). THE INSTALLATION OF A HIGH-FIELD NUCLEAR-MAGNETIC-RESONANCE SYSTEM FOR SPECTROSCOPY AND IMAGING. Brit j radiol, Vol.59 (704), pp. 820-820.

LEACH, M., HIND, A., SAUTER, R., REQUARDT, H. & WEBER, H. (1986). A DUAL-FREQUENCY NUCLEAR-MAGNETIC-RESONANCE SURFACE COIL FOR PROTON IMAGING AND P-31 SPECTROSCOPY. Brit j radiol, Vol.59 (704), pp. 820-821.

WEBB, S., LEACH, M.O., BENTLEY, R.E., MAUREEMOOTOO, K., TOMS, M.A. & YARNOLD, J. (1986). CLINICAL-EXPERIENCE WITH THE ROYAL MARSDEN HOSPITAL COMPUTED-TOMOGRAPHY SIMULATOR APPLIED TO PLANNING RADIOTHERAPY TREATMENT FOR BREAST-CANCER. Brit j radiol, Vol.59 (704), pp. 831-831.

MARSDEN, P., BATEMAN, J., OTT, R. & LEACH, M. (1986). THE DEVELOPMENT OF HIGH-EFFICIENCY CATHODE CONVERTERS FOR A MULTIWIRE PROPORTIONAL CHAMBER POSITRON CAMERA. Med phys, Vol.13 (5), pp. 703-706.

OTT, R.J., BATTY, V., CLACK, R., FLOWER, M.A., LEACH, M.O., MARSDEN, P., WEBB, S. & MCCREADY, V.R. (1985). LOW-COST POSITRON COMPUTED-TOMOGRAPHY. J photogr sci, Vol.33 (6), pp. 231-232.

WEBB, S., FLOWER, M., OTT, R., LEACH, M., FIELDING, S., INAMDAR, R., LOWERY, C. & BRODERICK, M. (1985). STUDIES IN THE PHYSICS OF IMAGING BY SINGLE PHOTON-EMISSION COMPUTED-TOMOGRAPHY. J photogr sci, Vol.33 (6), pp. 232-233.

OTT, R., BATEMAN, J., BATTY, V., CLACK, R., FIELDING, S., FLOWER, M., LEACH, M., MARSDEN, P., MCCREADY, V. & WEBB, S., et al. (1985). MEASUREMENT OF THYROID VOLUME AND UPTAKE USING POSITRON EMISSION TOMOGRAPHY. Brit j radiol, Vol.58 (692), pp. 824-824.

LEACH, M., WEBB, S. & BENTLEY, R. (1985). AN X-RAY-DETECTOR SYSTEM AND MODIFIED SIMULATOR PROVIDING CT IMAGES FOR RADIOTHERAPY DOSIMETRY PLANNING. Phys med biol, Vol.30 (4), pp. 303-311.

LEACH, M., WEBB, S., BENTLEY, R. & YARNOLD, J. (1985). THE APPLICATION OF A RADIOTHERAPY SIMULATOR BASED CT SCANNER FOR RADIOTHERAPY TREATMENT PLANNING. Phys med biol, Vol.30 (1), pp. 94-94.

WEBB, S., LONG, A., OTT, R., LEACH, M. & FLOWER, M. (1985). CONSTRAINED DECONVOLUTION OF SPECT LIVER TOMOGRAMS BY DIRECT DIGITAL IMAGE-RESTORATION. Med phys, Vol.12 (1), pp. 53-58.

OTT, R.J., BATTY, V., CLACK, R., FLOWER, M.A., LEACH, M.O., MARSDEN, P., MCCREADY, V.R. & WEBB, S. (1985). USE OF PET FOR ESTIMATION OF RADIATION-DOSE VARIATIONS WITHIN THE THYROID FROM RADIOIODINE THERAPY IN THYROTOXIC PATIENTS. J nucl med, Vol.26 (5), pp. P30-P31.

WEBB, S., OTT, R.J., BATEMAN, J.E., FLESHER, A.C., FLOWER, M.A., LEACH, M.O., MARSDEN, P., KHAN, O. & MCCREADY, V.R. (1984). TUMOR-LOCALIZATION IN ONCOLOGY USING POSITRON EMITTING RADIOPHARMACEUTICALS AND A MULTIWIRE PROPORTIONAL CHAMBER POSITRON CAMERA - TECHNIQUES FOR 3D-DECONVOLUTION. Nucl instrum meth a, Vol.221 (1), pp. 233-241.

LEACH, M.O., FLOWER, M.A., OTT, R.J. & WEBB, S. (1984). THE MEASUREMENT OF RESOLUTION IN SINGLE PHOTON-EMISSION COMPUTERIZED-TOMOGRAPHY. Phys med biol, Vol.29 (3), pp. 282-284.

FLOWER, M., OTT, R., WEBB, S., LEACH, M., MARSDEN, P., KHAN, O., MCCREADY, V., BATEMAN, J., FLESHER, A., SHARMA, H., et al. (1984). A CLINICAL-EVALUATION OF A PROTOTYPE POSITRON CAMERA FOR LONGITUDINAL EMISSION TOMOGRAPHY. Brit j radiol, Vol.57 (684), pp. 1103-1117.

FLOWER, M., LEACH, M., OTT, R., WEBB, S., BRODERICK, M., INAMDAR, R., LOWRY, C., GREY, L. & KALIRAI, T. (1984). TECHNICAL EVALUATION AND DEVELOPMENT OF A GE-400/A CAMERA AND STAR COMPUTER FOR QUANTITATIVE EMISSION TOMOGRAPHY. Brit j radiol, Vol.57 (682), pp. 943-944.

OTT, R., WEBB, S., FLOWER, M., LEACH, M., MARSDEN, P., BATEMAN, J., FLESHER, A., KHAN, O. & MCCREADY, V. (1984). POSITRON EMISSION TOMOGRAPHY IN ONCOLOGY - PHYSICAL PROBLEMS AND CLINICAL-RESULTS. Brit j radiol, Vol.57 (682), pp. 950-950.

LEACH, M., BELL, C. & HARVEY, T. (1984). THE RELEASE RATE OF AR-37 FROM HUMAN-SUBJECTS FOLLOWING INTRAVENOUS-INJECTION. Phys med biol, Vol.29 (7), pp. 779-788.

OTT, R.J., FLOWER, M.A., KHAN, O., KALIRAI, T., WEBB, S., LEACH, M.O. & MCCREADY, V.R. (1983). A COMPARISON BETWEEN 180-DEGREES AND 360-DEGREES DATA RECONSTRUCTION IN SINGLE PHOTON-EMISSION COMPUTED-TOMOGRAPHY OF THE LIVER AND SPLEEN. Brit j radiol, Vol.56 (672), pp. 931-937.

WEBB, S., FLOWER, M.A., OTT, R.J., LEACH, M.O. & INAMDAR, R. (1983). THE SPATIAL-RESOLUTION OF A ROTATING GAMMA-CAMERA TOMOGRAPHIC FACILITY. Brit j radiol, Vol.56 (672), pp. 939-944.

OTT, R.J., BATEMAN, J.E., FLESHER, A.C., FLOWER, M.A., LEACH, M.O., WEBB, S., KHAN, O. & MCCREADY, V.R. (1983). PRELIMINARY CLINICAL IMAGES FROM A PROTOTYPE POSITRON CAMERA. Brit j radiol, Vol.56 (670), pp. 773-776.

WEBB, S., FLOWER, M.A., OTT, R.J. & LEACH, M.O. (1983). A COMPARISON OF ATTENUATION CORRECTION METHODS FOR QUANTITATIVE SINGLE PHOTON-EMISSION COMPUTED-TOMOGRAPHY. Phys med biol, Vol.28 (9), pp. 1045-1056.

ROBINS, A.B. & LEACH, M.O. (1983). PHARMACOKINETICS OF THERAPEUTIC DOSES OF ISOTOPICALLY LABELED PLATINUM ANTI-TUMOR AGENTS IN THE MOUSE AND RAT. Cancer treat rep, Vol.67 (3), pp. 245-252.

LEACH, M.O., BELL, C.M. & THOMAS, B.J. (1983). THE RETENTION AND RELEASE OF AR-37 FROM SAMPLES OF HUMAN-BONE EXAMINED INVITRO AND A REVIEW OF THE IMPLICATIONS FOR ARGON TRANSFER FROM BONE INVIVO. Phys med biol, Vol.28 (4), pp. 389-405.

FLOWER, M.A., OTT, R.J., KHAN, O., LEACH, M.O., MCCREADY, V.R., WEBB, S., BATEMAN, J.E. & FLESHER, A.C. (1983). PRELIMINARY CLINICAL-STUDIES USING A PROTOTYPE MULTIWIRE PROPORTIONAL CHAMBER POSITRON CAMERA. J nucl med, Vol.24 (5), pp. P103-P104.

OTT, R.J., KHAN, O., FLOWER, M.A., KALIRAI, T., LEACH, M.O., WEBB, S. & MCCREADY, V.R. (1983). A COMPARISON BETWEEN 180-DEGREES AND 360-DEGREES DATA RECONSTRUCTION IN SINGLE PHOTON-EMISSION COMPUTED-TOMOGRAPHY OF THE LIVER AND SPLEEN. Eur j nucl med, Vol.8 (5), pp. A3-A3.

OTT, R.J., BATEMAN, J.E., FLOWER, M.A., FLESHER, A.C., LEACH, M.O., WEBB, S., KHAN, O. & MCCREADY, V.R. (1983). PRELIMINARY PATIENT STUDIES WITH A MULTIWIRE PROPORTIONAL CHAMBER POSITRON CAMERA. Eur j nucl med, Vol.8 (5), pp. A43-A43.

MCCREADY, V.R., FLOWER, M.A., OTT, R., SMYTHE, J. & YARNOLD, J. (1983). QUANTITATIVE STUDIES OF GA-67 UPTAKE IN HUMAN-LUNG TUMORS DURING CHEMOTHERAPY. Eur j nucl med, Vol.8 (5), pp. A24-A24.

LEACH, M.O., WEBB, S. & BENTLEY, R.E. (1982). A ROTATE-TRANSLATE CT SCANNER PROVIDING CROSS-SECTIONAL DATA SUITABLE FOR PLANNING THE DOSIMETRY OF RADIOTHERAPY TREATMENT. Med phys, Vol.9 (2), pp. 269-278.

WEBB, S., OTT, R.J., FLOWER, M.A., LEACH, M.O. & GREY, L. (1982). LONGITUDINAL TOMOGRAPHY USING A 3 PINHOLE APERTURE ATTACHED TO A GAMMA-CAMERA. Phys med biol, Vol.27 (1), pp. 165-165.

LEACH, M.O. & BELL, C.M. (1982). BLOOD-FLOW MEASUREMENTS AND THE PARTITION-COEFFICIENT OF XE-133 IN BONE. Phys med biol, Vol.27 (11), pp. 1401-1403.

BELL, C.M. & LEACH, M.O. (1982). A COMPARTMENTAL MODEL FOR INVESTIGATING THE INFLUENCE OF PHYSIOLOGICAL FACTORS ON THE RATE OF WASHOUT OF XE-133 AND AR-37 FROM THE BODY. Phys med biol, Vol.27 (9), pp. 1105-1117.

LEACH, M.O. & BELL, C.M. (1982). THE PREPARATION OF AR-37 IN STERILE SOLUTION SUITABLE FOR INJECTION INVIVO. Int j appl radiat is, Vol.33 (7), pp. 586-588.

LEACH, M.O. (1982). CORRECTION. International journal of applied radiation and isotopes, Vol.33 (12), pp. 1481-1481.

LEACH, M.O., BELL, C.M., THOMAS, B.J., DABEK, J.T., JAMES, H.M., CHETTLE, D.R. & FREMLIN, J.H. (1978). INVIVO MEASUREMENT OF CALCIUM BY AR-37 METHOD - STUDY OF EFFECT OF RECIRCULATING BREATH COLLECTION SYSTEMS ON EXHALATION RATE. Phys med biol, Vol.23 (2), pp. 282-290.

BELL, C.M., LEACH, M.O., DABEK, J.T., CHETTLE, D.R., JAMES, H., THOMAS, B.J. & FREMLIN, J.H. (1978). PROBLEMS IN INTERPRETATION OF INVIVO MEASUREMENT OF CALCIUM BY AR-37 METHOD - INVESTIGATION OF INERT-GAS ELIMINATION IN HUMANS. J nucl med, Vol.19 (1), pp. 54-60.

LEACH, M.O., THOMAS, B.J. & VARTSKY, D. (1977). TOTAL-BODY NITROGEN MEASURED BY N-14(N,2N)N-13 METHOD - STUDY OF INTERFERING REACTIONS AND VARIATION OF SPATIAL SENSITIVITY WITH DEPTH. Int j appl radiat is, Vol.28 (3), pp. 263-269.

Kurhanewicz, J., Vigneron, D.B., Brindle, K., Chekmenev, E.Y., Comment, A., Cunningham, C.H., Deberardinis, R.J., Green, G.G., Leach, M.O., Rajan, S.S., et al. Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research. Neoplasia, Vol.2 (13), pp. 81-97.

Arias-Mendoza, F., Payne, G.S., Zakian, K., Stubbs, M., O'Connor, O.A., Mojahed, H., Smith, M.R., Schwarz, A.J., Shukla-Dave, A., Howe, F., et al. Noninvasive Phosphorus Magnetic Resonance Spectroscopic Imaging Predicts Outcome to First-line Chemotherapy in Newly Diagnosed Patients with Diffuse Large B-Cell Lymphoma. Academic radiology, Vol.20, pp. 1122-1129.

Hill, D.K., Ortom, M.R., Mariotti, E., Boult, J.K., Panek, R., Jafar, M., Parkes, H.G., Jamin, Y., Miniotis, M.F., Al-Saffar, M.S., et al. Model Free Approach to Kinetic Analysis of Real-Time Hyperpolarized 13C Magnetic Resonance Spectroscopy Data. Plos one, Vol.9 (8).  show abstract

Borri, M., Schmidt, M.A., Powell, C., Koh, D.-., Riddell, A.M., Partridge, M., Bhide, S.A., Nutting, C.M., Harrington, K.J., Newbold, K.L., et al. Characterizing Heterogeneity within Head and Neck Lesions Using Cluster Analysis of Multi-Parametric MRI Data. Plos one, Vol.10 (9), pp. e0138545-e0138545.

Ledger, A.E., Scurr, E.D., Hughes, J., Macdonald, A., Wallace, T., Thomas, K., Wilson, R., Leach, M.O. & Schmidt, M.A. Comparison of Dixon Sequences for Estimation of Percent Breast Fibroglandular Tissue. Plos one, Vol.11 (3), pp. e0152152-e0152152.

Blackledge, M.D., Tunariu, N., Orton, M.R., Padhani, A.R., Collins, D.J., Leach, M.O. & Koh, D.-. Inter- and Intra-Observer Repeatability of Quantitative Whole-Body, Diffusion-Weighted Imaging (WBDWI) in Metastatic Bone Disease. Plos one, Vol.11 (4), pp. e0153840-e0153840.

Payne, G.S., Harris, L.M., Cairns, G.S., Desouza, N.M., Saran, F. & Leach, M.O. Validating a robust double-quantum-filtered 1H MRS lactate measurement method in high-grade brain tumours. Nmr in biomedicine, .

Leach, M., Mossop, H., Blackledge, M., Rata, M., McDonald, A., Rescigno, P., Zafeiriou, Z., Porta, N., Hall, E., De Bono, J., et al. Diffusion-weighted imaging as a treatment response biomarker evaluating bone metastases in prostate cancer. Radiology, .

Eeles, R., Saya, S., Thomas, S., Taylor, N., Benafif, S., Bancroft, E., Pope, J., Chamberlain, A., Gunapala, R., Leach, M., et al. Baseline Results from the UK SIGNIFY Study: A whole-Body MRI Screening Study in TP53 Mutation Carriers and Matched Controls. Familial cancer, .

Freedman, J. T2-Weighted 4D Magnetic Resonance Imaging for Application in Magnetic Resonance-Guided Radiotherapy Treatment Planning. Investigative radiology, .

Shah, A., Delgado-Goni, T., Casals Galobart, T., Wantuch, S., Jamin, Y., Leach, M., Robinson, S., Bamber, J. & Beloueche-Babari, M. Detecting human melanoma cell re-differentiation following BRAF or heat shock protein 90 inhibition using photoacoustic and magnetic resonance imaging. Scientific reports, .

Al-Saffar, N.M., Agliano, A., Marshall, L.V., Jackson, L.E., Balarajah, G., Sidhu, J., Clarke, P.A., Jones, C., Workman, P., Pearson, A.D., et al. In vitro nuclear magnetic resonance spectroscopy metabolic biomarkers for the combination of temozolomide with PI3K inhibition in paediatric glioblastoma cells. Plos one, Vol.12 (7), pp. e0180263-e0180263.

Jerome, N., Boult, J., Orton, M., d'Arcy, J.A., Nerurkar, A., Leach, M., Koh, D., Collins, D.J. & Robinson, S. Characterisation of fibrosis in chemically-induced rat mammary carcinomas using multi-modal endogenous contrast MRI on a 1 5T clinical platform. European radiology, .

Denholm, R., De Stavola, B., Hipwell, J., Doran, S.J., Busana, M., Jeffreys, M., Leach, M.O., Hawkes, D. & dos-Santos-Silva, I. Growth trajectories, breast size, and breast-tissue composition in a British pre-birth cohort of young women. American journal of epidemiology, .

Hill, D.K., Heindl, A., Zormpas-Petridis, K., Collins, D.J., Euceda, L.R., Rodrigues, D.N., Moestue, S.A., Jamin, Y., Koh, D.-., Yuan, Y., et al. Non-Invasive Prostate Cancer Characterization with Diffusion-Weighted MRI: Insight from In silico Studies of a Transgenic Mouse Model. Frontiers in oncology, Vol.7.

Bailey, C., Collins, D.J., Tunariu, N., Orton, M.R., Morgan, V.A., Feiweier, T., Hawkes, D.J., Leach, M.O., Alexander, D.C. & Panagiotaki, E., et al. Microstructure Characterization of Bone Metastases from Prostate Cancer with Diffusion MRI: Preliminary Findings. Frontiers in oncology, Vol.8.

Freedman, J., Collins, D., Gurney-Champion, O., Nill, S., Oelfke, U., Leach, M., Wetscherek, A. & McClelland, J. Super-resolution T2-weighted 4D MRI for image guided radiotherapy. Radiotherapy and oncology, .

Doran, S. & Leach, M.O. Circulating growth and sex hormone levels and breast-tissue composition in young nulliparous women. Cancer epidemiology, biomarkers and prevention, .

Baker, L.C., Sikka, A., Price, J.M., Boult, J.K., Lepicard, E.Y., Box, G., Jamin, Y., Spinks, T.J., Kramer-Marek, G., Leach, M.O., et al. Evaluating Imaging Biomarkers of Acquired Resistance to Targeted EGFR Therapy in Xenograft Models of Human Head and Neck Squamous Cell Carcinoma. Frontiers in oncology, Vol.8.

Al-Saffar, N., Wong Te Fong, A., Gowan, S., Boult, J., Robinson, S., Eccles, S., Yap, T., Leach, M., Paravati, R. & Chung, Y., et al. Metabolic biomarkers for the AKT inhibitor MK-2206 in pre-clinical models of human colorectal and prostate carcinoma. British journal of cancer, .

Freedman, J.N., Bainbridge, H.E., Nill, S., Collins, D.J., Kachelrieß, M., Leach, M.O., McDonald, F., Oelfke, U. & Wetscherek, A. Synthetic 4D-CT of the thorax for treatment plan adaptation on MR-guided radiotherapy systems. Physics in medicine & biology, Vol.64 (11), pp. 115005-115005.


Conferences

Beloueche-Babari, M., Galobart, T.C., Wantuch, S., Smith, P.D. & Leach, M.O. (2017). Abstract 444: Monocarboxylate transporter 1 inhibition with AZD3965 increases cancer cell dependence on bioenergetic metabolism predicating combination therapy with mitochondrial inhibitors, Presented at Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC, Molecular and Cellular Biology, Genetics, .

Den Otter, L.A., Kaza, E., Kierkels, R.G., Leach, M.O., Collins, D.J., Langendijk, J.A. & Knopf, A.C. (2017). OC-0303: Evaluation of lung anatomy vs. lung volume reproducibility for scanned proton treatments under ABC., Radiotherapy and Oncology, Vol.123, pp.S156-S157.

Schmidt, M.A., Panek, R., Colgan, R., Hughes, J., Sohaib, A., Saran, F., Murray, J., Bernard, J., Ravell, P., Nittka, M., et al. (2016). Evaluation of SEMAC MRI metal artifact reduction for orthopaedic implants in radiotherapy planning, RADIOTHERAPY AND ONCOLOGY, Vol.119, p.S899.

Wholey, E.G., Parkes, H.G., Workman, P., Leach, M.O. & Beloueche-Babari, M. (2015). Abstract 1158: Real-time assessment of uptake and utilization of lactate in intact human breast cancer cells using a 1H-NMR-based assay, Presented at Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA, Molecular and Cellular Biology, .

Andrejeva, G., Lin, G., Parkes, H.G., Mui, J., Wong Te Fong, A.-., Vizcay-Barrena, G., Fleck, R., Leach, M.O. & Chung, Y.-. (2015). Abstract 2897: Phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy, Presented at Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA, Molecular and Cellular Biology, .

Costa, M., McErlean, C., Rivens, I., Adamovics, J., Leach, M.O., Haar, G.T. & Doran, S.J. (2015). PRESAGE®as a new calibration method for high intensity focused ultrasound therapy, Journal of Physics: Conference Series, Vol.573, p.012026.

McErlean, C., Bräuer-Krisch, E., Adamovics, J., Leach, M.O. & Doran, S.J. (2015). High resolution 3D dosimetry for microbeam radiation therapy using optical CT, Journal of Physics: Conference Series, Vol.573, p.012032.

Fong, A.-., Andrejeva, G., Bielen, A., Jones, C., Griffiths, J., Leach, M.O. & Chung, Y.-. (2014). Abstract 2451: Insulin-like growth factor-1 receptor (IGF-1R) inhibitors downregulate p53 expression and upregulate the Warburg effect in paediatric glioblastoma cells, Presented at Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA, Molecular and Cellular Biology, .

Lechon, F.C., Fowkes, L., Khabra, K., Martin-Retortillo, L.M., Marshall, L.V., Vaidya, S., Koh, D.-., Leach, M.O., Pearson, A.D. & Zacharoulis, S., et al. (2014). CHARACTERISATION OF PSEUDOPROGRESSION IN CHILDREN AND ADOLESCENTS WITH HIGH GRADE GLIOMAS, NEURO-ONCOLOGY, Vol.16, p.46.

Price, J.M., Baker, L.C., Boult, J.K., Box, C., Kramer-Marek, G., Murray, I., Robinson, S.P. & Leach, M.O. (2014). 18F-fluorodeoxyglucose (FDG) uptake is increased in epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) resistant compared with sensitive head and neck cancer xenografts, EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, Vol.41, p.S638.

Box, C., Baker, L.C., Beloueche-Babari, M., Rogers, S.J., Box, G.M., Harrington, K.J., Leach, M.O., Robinson, S.P. & Eccles, S.A. (2013). 2D, 3D and in vivo models of head and neck cancer identify novel correlates of resistance to epidermal growth factor receptor tyrosine kinase inhibitors, EUROPEAN JOURNAL OF CANCER, Vol.49, p.S772.

Welsh, L.C., Powell, C., Schmidt, M., Borri, M., Koh, D.M., Riddell, A., Bhide, S.A., Nutting, C.M., Leach, M.O. & Newbold, K.L., et al. (2013). Changes in brain white matter diffusion tensor imaging indices following radiotherapy for head & neck cancer, EUROPEAN JOURNAL OF CANCER, Vol.49, p.S758.

Spinks, T.J., Karia, D., Flux, G. & Leach, M. (2013). Performance Characteristics of the Albira Tri-Modal Pre-clinical Scanner, EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, Vol.40, p.S409.

Te Fong, A.-., Jones, C., Griffiths, J.R., Leach, M.O. & Chung, Y.-. (2013). Picropodophyllin downregulates p53 and increases the Warburg effect in pediatric glioblastoma cells., CANCER RESEARCH, Vol.73 (8).

Tilanus-Linthorst, M.M., Lingsma, H., Evans, D.G., Kaas, R., Manders, P., Hooning, M.J., van Asperen, C.J., Oosterwijk, J.C., Leach, M.O. & Steyerberg, E.J., et al. (2012). Optimal Age to Start Preventive Measures in Women with BRCA1/2 Mutations or High Familial Breast Cancer Risk, EUROPEAN JOURNAL OF CANCER, Vol.48, pp.S83-S84.

Rossiter, J., Arvanitis, T., Natarajan, K., Wilson, M., Davies, N., Gill, S., Grazier, R., Crouch, J., Auer, D., Clark, C., et al. (2012). A CLINICAL TRIALS E-REPOSITORY WITH INTEGRATED CONVENTIONAL AND FUNCTIONAL IMAGING DATA, NEURO-ONCOLOGY, Vol.14, p.124.

Beloueche-Babari, M., Jamin, Y., Walker-Samuel, S., Smith, P.D., Waterton, J.C., Halliday, J., Barjat, H., Workman, P., Leach, M.O. & Robinson, S.P., et al. (2012). Non-invasive Imaging of Response to MEK Inhibition With Selumetinib (AZD6244, ARRY-142886) in a Human Colorectal Cancer Xenograft Using Diffusion-Weighted MRI, EUROPEAN JOURNAL OF CANCER, Vol.48, p.S202.

Ledger, A.E., Borri, M., Schmidt, M., Pope, R., Scurr, E., Wallace, T., Richardson, C., Usher, M., Allen, S., Wilson, R., et al. (2012). Assessment of the dynamic range in dynamic contrast-enhanced magnetic resonance imaging breast examinations, BREAST CANCER RESEARCH, Vol.14.

Jafar, M., Giles, S., Morgan, V., Schmidt, M., Leach, M.O., deSouza, N.M. & IEEE, (2012). EVALUATION OF DISTORTION CORRECTION OF DIFFUSION-WEIGHTED MR IMAGES OF HUMAN CERVIX, 2012 9TH IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING (ISBI), , pp.514-517.

Davies, N.P., Arvanitis, T.N., Auer, D., French, A., Grazier, R., Grundy, R., Howe, F.A., Hargrave, D., Jaspan, T., Lateef, S., et al. (2010). MULTICENTRE PROSPECTIVE CLASSIFICATION OF CHILDHOOD BRAIN TUMOURS BASED ON 'H MRS METABOLITE PROFILES, Presented at 14th International Symposium on Pediatric Neuro-Oncology, Vienna, AUSTRIA. NEURO-ONCOLOGY, Vol.12 (6), p.II32.

Arvanitis, T.N., Natarajan, K., Rossiter, J., Ting, J.I., Sun, Y., Wilson, M., Davies, N.P., Orphanidou-Vlachou, E., Grazier, R., Crouch, J., et al. (2010). THE CHILDREN'S CANCER AND LEUKAEMIA GROUP (CCLG) FUNCTIONAL IMAGING E-REPOSITORY FOR CLINICAL TRIALS OF CHILDHOOD BRAIN TUMOURS, Presented at 14th International Symposium on Pediatric Neuro-Oncology, Vienna, AUSTRIA. NEURO-ONCOLOGY, Vol.12 (6), p.II118.

Leach, M. (2010). FUNCTIONAL MR FOR TREATMENT PLANNING, RADIOTHERAPY AND ONCOLOGY, Vol.96, p.S199.

Mendoza, F.A., Payne, G., Zakian, K., Stubbs, M., Majahed, H., Schwarz, A., Dave, A.S., Howe, F., Poptani, H., Lee, S.C., et al. (2010). Phosphorus Magnetic Resonance Spectroscopy Predicts Outcome to Chemotherapy In Patients with Diffuse Large B Cell Lymphoma A Prospective International Multicenter Analysis of a Pretreatment Metabolic Biomarker of Response, Presented at 52nd Annual Meeting of the American-Society-of-Hematology (ASH), Orlando, FL. BLOOD, Vol.116 (21), pp.1279-1280.

Arias-Mendoza, F., Payne, G., Zakian, K., Stubbs, M., Mojahed, H., Schwarz, A., Shukla-Dave, A., Howe, F., Poptani, H., Lee, S.C., et al. (2010). Phosphorus Magnetic Resonance Spectroscopy Predicts Outcome to Chemotherapy In Patients with Diffuse Large B-Cell Lymphoma: A Prospective International Multicenter Analysis of a Pretreatment Metabolic Biomarker of Response., Presented at 52nd Annual Meeting of the American-Society-of-Hematology (ASH), Orlando, FL. BLOOD, Vol.116 (21), pp.1279-1280.

Reed, S., Ertas, G., Doran, S., Warren, R.M. & Leach, M.O. (2010). Robustness of interactive intensity thresholding based breast density assessment in MR-Mammography, Presented at Conference on Medical Imaging 2010 - Computer-Aided Diagnosis, San Diego, CA. MEDICAL IMAGING 2010: COMPUTER - AIDED DIAGNOSIS, Vol.7624,

Solanky, B., Chung, Y.L., Leach, M.O., So, P.W. & Modo, M. (2010). Characterization of a Human Neural Stem Cell Biomarker Using Magnetic Resonance Spectroscopy, Presented at 17th Annual Meeting of the American-Society-for-Neural-Therapy-and-Repair, Clearwater, FL. CELL TRANSPLANTATION, Vol.19 (3), pp.362-363.

Ertas, G., Reed, S. & Leach, M.O. (2010). Comparison of breast density assessments based on interactive thresholding and automated fast fuzzy c-means clustering in three-dimensional MR imaging, WORLD CONGRESS ON MEDICAL PHYSICS AND BIOMEDICAL ENGINEERING, VOL 25, PT 4: IMAGE PROCESSING, BIOSIGNAL PROCESSING, MODELLING AND SIMULATION, BIOMECHANICS, Vol.25, pp.1893-1896.

Chung, Y., Troy, H., Payne, G.S., Stubbs, M., Judson, I.R., Griffiths, J.R. & Leach, M.O. (2009). Abstract A224: Noninvasive PD markers of a pyruvate dehydrogenase kinase inhibitor, dichloroacetate, in human colon carcinoma xenografts, Presented at Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics--Nov 15-19, 2009; Boston, MA, Imaging, .

Chung, Y., Troy, H., Stubbs, M., Thurston, D.E., Judson, I.R., Leach, M.O. & Griffiths, J.R. (2009). Abstract A228: Noninvasive magnetic resonance spectroscopic PD markers of a minor‐groove interstrand cross‐linking agent (BN2629) in human colon carcinoma and melanoma xenografts, Presented at Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics--Nov 15-19, 2009; Boston, MA, Imaging, .

Chung, Y., Troy, H., Judson, I.R., Griffiths, J.R., Leach, M.O. & Eykyn, T. (2009). Abstract A72: Assessment of pyuvate dehydrogenase kinase inhibition by dichloroacetate in human colon carcinoma cells by dynamic hyperpolarized13C MRS and steady state1H MRS, Presented at Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics--Nov 15-19, 2009; Boston, MA, Cellular Responses to Therapy, .

Li, S.P., Makris, A., Taylor, N.J., Beresford, M.J., Ah-See, M.-., Stirling, J.J., Collins, D.J., d'Arcy, J.A., Leach, M.O. & Padhani, A.R., et al. (2009). Greater Anti-Angiogenic Effects with Docetaxel Compared with Anthracyclines in the Neoadjuvant Treatment of Breast Cancer, CANCER RESEARCH, Vol.69 (24), p.768S.

Arias-Mendoza, F., Leach, M.O., Koutcher, J.A., Griffiths, J.R., Heerschap, A., Glickson, J.D., O'Connor, O.A., Brown, T.R. & Cooperat Grp MR Applicat Canc, (2009). Prediction of treatment response in subtypes of non-Hodgkin's lymphoma by in vivo P-31 MR spectroscopy before treatment, Presented at 45th Annual Meeting of the American-Society-of-Clinical-Oncology, Orlando, FL. JOURNAL OF CLINICAL ONCOLOGY, Vol.27 (15),

Arias-Mendoza, F., Payne, G.S., Zakian, K., Stubbs, M., Cruz-Lobo, J.G., Schwarz, A.J., Shukla-Dave, A., Howe, F., Maisey, N.R., Cunningham, D., et al. (2008). Treatment response predictor using 31P MRS for chop and R-chop therapy in diffuse large B-cell lymphoma, Presented at 10th International Conference on Malignant Lymphoma, Lugano, SWITZERLAND. ANNALS OF ONCOLOGY, Vol.19, p.147.

Beloueche-Babari, M., Tiet, M.Y., Jackson, L.E., Workman, P. & Leach, M.O. (2008). Heat shock protein 90 inhibitors modulate choline phospholipid profiles and metabolizing enzymes in human melanoma cells, Presented at 20th Meeting of the European-Association-for-Cancer-Research, Lyon, FRANCE. EJC SUPPLEMENTS, Vol.6 (9), pp.84-85.

Miniotis, M.F., Workman, P., Leach, M.O. & Beloueche-Babari, M. (2008). Inhibition of MEK1/2 signalling results in decreased levels of intracellular lactate in human melanoma and colorectal cancer cells as observed with magnetic resonance spectroscopy, Presented at 20th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Geneva, SWITZERLAND. EJC SUPPLEMENTS, Vol.6 (12), pp.27-28.

Nathan, P.D., Judson, I., Padhani, A., Harris, A., Carden, C.P., Smythe, J., Collins, D., Leach, M., Walicke, P. & Rustin, G.J., et al. (2008). A phase I study of combretastatin A4 phosphate (CA4P) and bevacizumab in subjects with advanced solid tumors, JOURNAL OF CLINICAL ONCOLOGY, Vol.26 (15).

Leach, M.O., Eeles, R., Evans, G., Easton, D., Warren, R., Gayther, S., Ramus, S., Boggis, C., Lennard, F., Bryant, E., et al. (2007). The UK MARIBS study of MRI breast screening: progress on genetic and density projects, Presented at 10th Nottingham International Breast Cancer Conference, Nottingham, ENGLAND. EJC SUPPLEMENTS, Vol.5 (3), p.18.

Tilanus-Linthorst, M.M., Obdeijn, I.M., Hop, W.C., Causer, P., Leach, M.O., Warner, E., Pointon, L., Hill, K., Klijn, J.G., Warren, R.M., et al. (2007). A BRCA1 or BRCA2 mutation and young age predict fast breast cancer growth. Implications for screening?, Presented at 30th Annual San Antonio Breast Cancer Symposium, San Antonio, TX. BREAST CANCER RESEARCH AND TREATMENT, Vol.106, pp.S95-S96.

Leach, M.O. (2007). Principle of magnetic resonance, Presented at Conference of the NATO-Advanced-Study-Institute on Optimising Detectors, Imaging and Computing Technologies form Nuclear Physics in General and Security Applications, Archamps, FRANCE. Physics for Medical Imaging Applications, Vol.240, pp.25-36.

Leach, M.O. (2006). MRI for breast cancer screening, Presented at 31st ESMO Congress, Istanbul, TURKEY. ANNALS OF ONCOLOGY, Vol.17, pp.X325-X331.

Tanner, C., Hawkes, D.J., Khazen, M., Kessar, P., Leach, M.O. & IEEE, (2006). Does registration improve the performance of a computer aided diagnosis system for dynamic contrast-enhanced MR mammography?, 2006 3RD IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING: MACRO TO NANO, VOLS 1-3, , pp.466-+.

Leach, M.O. & Collaborators MARIBS Study, (2005). Screening in women at genetic risk of breast cancer: Results of the UK multicentre study of magnetic resonance imaging (MRI) and X-ray mammography (XRM)., Presented at 41st Annual Meeting of the American-Society-of-Clinical-Oncology, Orlando, FL. JOURNAL OF CLINICAL ONCOLOGY, Vol.23 (16), p.9S.

Ah-See, M.W., Padhani, A.R., Taylor, N.J., Harris, A.L., Burcombe, R.J., Fox, S.B., Richman, P.I., Daley, F.M., Stirling, J.J., Leach, M.O., et al. (2005). Lack of correlation between microvessel density & pericyte coverage index within breast cancer biopsies & functional dynamic contrast-enhanced MRI-derived vascular parameters, Presented at 28th Annual San Antonio Breast Cancer Symposium, San Antonio, TX. BREAST CANCER RESEARCH AND TREATMENT, Vol.94, pp.S74-S75.

Syms, R.R., Ahmad, M.M., Young, I.R., Gilderdale, D., Collins, D.J. & Leach, M.O. (2005). Micro-coils for MR spectroscopy by deep silicon etching, Journal of Physics: Conference Series, Vol.15, pp.13-18.

Lessmann, B., Degenhard, A., Kessar, P., Pointon, L., Khazen, M., Leach, M.O. & Nattkemper, T.W. (2005). SOM-based wavelet filtering for the exploration of medical images, Presented at 15th International Conference on Artificial Neural Networks (ICANN 2005), Warsaw, POLAND. ARTIFICIAL NEURAL NETWORKS: BIOLOGICAL INSPIRATIONS - ICANN 2005, PT 1, PROCEEDINGS, Vol.3696, pp.671-676.

Syms, R.R., Ahmad, M.M., Young, I.R., Gilderdale, D., Collins, D.J., Leach, M.O. & IEEE, (2005). Batch fabrication of micro-coils for MR spectroscopy on silicon, 2005 IEEE SENSORS, VOLS 1 AND 2, , pp.227-230.

Tanner, C., Khazen, M., Kessar, P., Leach, M.O. & Hawkes, D.J. (2004). Classification improvement by segmentation refinement: Application to contrast-enhanced MR-mammography, Presented at 7th International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI 2004), St Malo, FRANCE. MEDICAL IMAGE COMPUTING AND COMPUTER-ASSISTED INTERVENTION - MICCAI 2004, PT 1, PROCEEDINGS, Vol.3216, pp.184-191.

Anderson, J., Walker, L.G., Leach, M.O. & MRC Study Advisory Grp, (2004). Magnetic resonance imaging: an accepatble way of screening women with a family history of breast cancer, Presented at 27th Annual Charles A Colman San Antonio Breast Cancer Symposium, San Antonio, TX. BREAST CANCER RESEARCH AND TREATMENT, Vol.88, p.S188.

Saalbach, A., Twellmann, T., Nattkemper, T., White, M., Khazen, M. & Leach, M.O. (2004). Visualization of multivariate image data using image fusion and perceptually optimized color scales based on sRGB, Presented at Medical Imaging 2004, Medical Imaging 2004: Visualization, Image-Guided Procedures, and Display, .

Ah-See, M.W., Padhani, A.R., Taylor, N.J., Daley, F.M., Bentzen, S.M., Burcombe, R.J., Harrison, M., Stirling, J.J., Leach, M.O. & Makris, A., et al. (2004). Tumour microvasculature, assessment by dynamic contrast-enhanced MRI fails to correlate with VEGF expression in breast cancer biopsies, Presented at British Cancer Research Meeting 2004, Manchester, ENGLAND. BRITISH JOURNAL OF CANCER, Vol.91, p.S16.

Chung, Y.L., Troy, H., Judson, I.R., Leek, R., Leach, M.O., Stubbs, M., Harris, A.L. & Griffiths, J.R. (2004). Pharmacokinetic measurements of a 5FU pro-drug, capecitabine, in bladder tumours over-expressing thymidine phosphorylase, Presented at British Cancer Research Meeting 2004, Manchester, ENGLAND. BRITISH JOURNAL OF CANCER, Vol.91, p.S43.

Lee, C.P., Payne, G.S., Ruddle, R.R., Raynaud, F.I., Tan, S.K., Campbell, M.J., Tracy, M., McNamara, J.P., Leach, M.O., Judson, I.R., et al. (2004). Sr4554 as a non-invasive probe of tumour hypoxia detected by magnetic resonance spectroscopy: Results of a phase I trial, Presented at British Cancer Research Meeting 2004, Manchester, ENGLAND. BRITISH JOURNAL OF CANCER, Vol.91, p.S45.

Ah-See, M.W., Makris, A., Taylor, N.J., Harrison, M., Ostler, P.J., Richman, P.I., Stirling, J.J., Burcombe, R.J., Leach, M.O., Pittam, M.R., et al. (2004). Changes in dynamic contrast-enhanced MRI as an early predictor of response to neoadjuvant chemotherapy in primary breast cancer, Presented at British Cancer Research Meeting 2004, Manchester, ENGLAND. BRITISH JOURNAL OF CANCER, Vol.91, p.S22.

Degenhard, A., Mutz, M., Nattkemper, T.W., Saalbach, A., Twellmann, T., White, M.J., Khazen, M., Pointon, L. & Leach, M.O. (2004). Multiscale entropy analysis in dynamic contrast-enhanced MRI, Presented at Medical Imaging 2004, Medical Imaging 2004: Image Processing, .

Zheng, Y., Tanner, C., Hill, D.L., Hawkes, D.J., White, M.J., Khazen, M. & Leach, M.O. (2004). Alignment of dynamic contrast-enhanced MR volumes of the breast for a multicenter trial: an exemplar grid application, Presented at Medical Imaging 2004, Medical Imaging 2004: Image Processing, .

Ah-See, M.L., Makris, A., Taylor, N.J., Burcombe, R.J., Harrison, M., Stirling, J.J., Richman, P.I., Leach, M.O. & Padhani, A.R. (2004). Does vascular imaging with MRI predict response to neoadjuvant chemotherapy in primary breast cancer?, Presented at 40th Annual Meeting of the American-Society-of-Clinical-Oncology, New Orleans, LA. JOURNAL OF CLINICAL ONCOLOGY, Vol.22 (14), p.22S.

Chung, Y.L., Troy, H., Judson, I.R., Leek, R., Leach, M.O., Stubbs, M., Harris, A.L. & Griffiths, J.R. (2003). Pharmacokinetic measurements of a 5FU pro-drug, capecitabine, in bladder tumours over-expressing thymidine phosphorylase., Presented at AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, BOSTON, MASSACHUSETTS. CLINICAL CANCER RESEARCH, Vol.9 (16), pp.6257S-6258S.

Ah-See, M.L., Makris, A., Taylor, N.J., Harrison, M., Richman, P.I., D'arcy, J.A., Burcombe, R.J., Pittam, M.R., Ravichandran, D., Stirling, J.J., et al. (2003). Multi-functional magnetic resonance imaging predicts for clinico-pathological response to neoadjuvant chemotherapy in primary breast cancer., Presented at 26th Annual San Antonio Breast Cancer Symposium, SAN ANTONIO, TEXAS. BREAST CANCER RESEARCH AND TREATMENT, Vol.82, p.S59.

Chung, Y.L., Maxwell, R.J., Aboagye, E.A., Griffiths, J.R., Leach, M.O., Price, P., Rathbone, R., Zweit, J. & Workman, P. (2003). A framework for incorporating non-invasive pharmacokinetic and pharmacodynamic endpoints into the development of new anti-cancer drugs., CLINICAL CANCER RESEARCH, Vol.9 (16), p.6202S.

Vaidya, S.J., Chung, Y.L., Payne, G.S., Leach, M.O., Griffiths, J.R. & Pinkerton, C.R. (2003). Magnetic resonance spectroscopy (MRS) to study chemotherapy response in a paediatric embryonal rhabdomyosarcoma (Rd) model., Presented at British Cancer Research Meeting 2003, BOURNEMOUTH, ENGLAND. BRITISH JOURNAL OF CANCER, Vol.88, p.S17.

Ah-See, M.L., Taylor, N.J., Makris, A., Burcombe, R.J., Stirling, J.J., Cladd, H.J., Leach, M.O. & Padhani, A.R. (2003). Valuation of multi-functional dynamic contrast-enhanced MRI to predict response to neoadjuvant chemotherapy in primary breast cancer, BRITISH JOURNAL OF CANCER, Vol.88, p.S41.

Tanner, C., Degenhard, A., Schnabel, J.A., Castellano-Smith, A.D., Hayes, C., Sonoda, L.I., Leach, M.O., Hose, D.R., Hill, D.L. & Hawkes, D.J., et al. (2002). Comparison of biomechanical breast models: a case study, Presented at Medical Imaging 2002, Medical Imaging 2002: Image Processing, .

Schnabel, J.A., Tanner, C., Castellano-Smith, A.D., Degenhard, A., Hayes, C., Leach, M.O., Hose, D.R., Hill, D.L. & Hawkes, D.J. (2002). Finite-element based validation of nonrigid registration using single- and multilevel free-form deformations: application to contrast-enhanced MR mammography, Presented at Medical Imaging 2002, Medical Imaging 2002: Image Processing, .

Tanner, C., Schnabel, J.A., Degenhard, A., Castellano-Smith, A.D., Hayes, C., Leach, M.O., Hose, D.R., Hill, D.L. & Hawkes, D.J. (2002). Validation of volume-preserving non-rigid registration: Application to contrast-enhanced MR-mammography, Presented at 5th International Conference on Medical Image Computing and Computer-Assisted Intervention, TOKYO, JAPAN. MEDICAL IMAGE COMPUTING AND COMPUTER-ASSISTED INTERVENTION-MICCAI 2002, PT 1, Vol.2488, pp.307-314.

Leach, M.O. (2001). Assessing response to treatment using magnetic resonance, Presented at Topical Meeting on Medical Radiation Physics and Engineering (TM-MeRPE), LISBON, PORTUGAL. PHYSICA MEDICA, Vol.17, pp.50-52.

Anderson, J., Leach, M.O. & Walker, L.G. (2001). Annual screening for women with a family history of breast cancer: The relative impact of magnetic resonance and x-ray mammography, PSYCHO-ONCOLOGY, Vol.10 (3), p.264.

Anderson, J., Walker, L.G., Leach, M. & UK, M.R. (2000). MRI screening for breast cancer in women at genetic risk: Protocol for a psychosocial assessment of the relative impact of MRM and XRM, PSYCHO-ONCOLOGY, Vol.9 (5), p.447.

Workman, P., Aboagye, E., Burtles, S., Griffiths, J., Leach, M., Maxwell, R., McSheehy, P., Price, P. & Verdon, V. (1999). Development of novel pharmacokinetic and pharmacodynamic technologies for phase I clinical trials: The UKCRC experience and future plans., CLINICAL CANCER RESEARCH, Vol.5, p.3828S.

Rueckert, D., Sonoda, L.I., Denton, E.R., Rankin, S., Hayes, C., Leach, M.O., Hill, D.L. & Hawkes, D.J. (1999). Comparison and evaluation of rigid and nonrigid registration of breast MR images, Presented at Medical Imaging '99, Medical Imaging 1999: Image Processing, .

Rivens, I., Rowland, I., Denbow, M., Fisk, N., Leach, M. & ter Haar, G. (1998). Focused ultrasound surgery induced vascular occlusion in fetal medicine, Presented at Conference on Surgical Applications of Energy, SAN JOSE, CA. SURGICAL APPLICATIONS OF ENERGY, PROCEEDINGS OF, Vol.3249, pp.260-266.

Rueckert, D., Hayes, C., Studholme, C., Summers, P., Leach, M. & Hawkes, D.J. (1998). Non-rigid registration of breast MR images using mutual information, Presented at 1st International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI 98), CAMBRIDGE, MA. MEDICAL IMAGE COMPUTING AND COMPUTER-ASSISTED INTERVENTION - MICCAI'98, Vol.1496, pp.1144-1152.

Wolber, J., Rowland, I.J., Leach, M.O. & Bifone, A. (1998). Intravascular delivery of hyperpolarized (129)xenon for in vivo MRI, Presented at Joint 29th AMPERE / 13th ISMAR International Conference on Magnetic Resonance and Related Phenomena, BERLIN, GERMANY. APPLIED MAGNETIC RESONANCE, Vol.15 (3-4), pp.343-352.

Miller, N.R., Bamber, J.C., Doyley, M.M. & Leach, M.O. (1997). Visual detectability of elastic contrast in real-time ultrasound images, Presented at Medical Imaging 1997 Conference on Image Perception, NEWPORT BEACH, CA. IMAGE PERCEPTION, Vol.3036, pp.264-272.

Smith, T.A., Eccles, S., Box, G., Titley, J.C., Leach, M.O. & McCready, V.R. (1996). Phosphocholine and choline content of rat sarcoma cells grown in the presence and absence of serum, Presented at Symposium on Lipid Metabolism and Function in Cancer - Significance of Magnetic Resonance Spectroscopy (MRS) Measurements in Relation to Biochemical Processes and Cellular Control, at the 5th International Conference of Anticancer Research Eu Biomed 1, CORFU, GREECE. ANTICANCER RESEARCH, Vol.16 (3B), pp.1389-1392.

Parker, G.J., Padhani, A.R., Suckling, J., Tanner, S.F., Husband, J.E. & Leach, M.O. (1996). Parametric image overlay software for dynamic MR imaging studies (MR imaging workbench), RADIOLOGY, Vol.201, p.9112.

Finnigan, D.J., Tanner, S.F., Dearnaley, D.P., Edser, E., Horwich, A., Khoo, V.S., Mayles, W.P., Shentall, G. & Leach, M.O. (1996). Distortion-corrected MR images for pelvic radiotherapy treatment planning, Presented at 19th L H Gray Conference on Quantitative Imaging in Oncology, NEWCASTLE TYNE, ENGLAND. QUANTITATIVE IMAGING IN ONCOLOGY, , pp.72-76.

Leach, M.O. (1996). Quantitative assessment of tumour response - Quantitative assessment of tumour response using MRI/MRS, Presented at 19th L H Gray Conference on Quantitative Imaging in Oncology, NEWCASTLE TYNE, ENGLAND. QUANTITATIVE IMAGING IN ONCOLOGY, , pp.126-132.

Doyley, M.M., Bamber, J.C., Shiina, T. & Leach, M.O. (1996). Reconstruction of elastic modulus distribution from envelope detected B-mode data, Presented at 1996 IEEE Ultrasonic Symposium, SAN ANTONIO, TX. 1996 IEEE ULTRASONICS SYMPOSIUM, PROCEEDINGS, VOLS 1 AND 2, , pp.1611-1614.

GLAHOLM, J., COLLINS, D., MANSI, J., SHARP, J.C., LEACH, M.O., MCCREADY, V.R., SMITH, I.E., POWLES, T. & HIND, A.J. (1991). THE IMPORTANCE OF SIGNAL LOCALIZATION AND MEASUREMENT OF ABSOLUTE METABOLITE CHANGES WHEN MONITORING THE TREATMENT RESPONSE OF HUMAN BREAST-CARCINOMA WITH INVIVO P-31 NMR-SPECTROSCOPY, RADIOACTIVE ISOTOPES IN CLINICAL MEDICINE AND RESEARCH, , pp.158-164.

GLAHOLM, J., SHARP, J.C., COLLINS, D.J., MCREADY, V.R., HIND, A. & LEACH, M.O. (1989). INVIVO P-31 NUCLEAR-RESONANCE SPECTROSCOPY OF HUMAN-BREAST CARCINOMA - THE IMPORTANCE OF LOCALIZATION, BRITISH JOURNAL OF CANCER, Vol.59 (5), pp.830-831.

Tanner, C., Degenhard, A., Schnabel, J.A., Smith, A.C., Hayes, C., Sonoda, L.I., Leach, M.O., Hose, D.R., Hill, D.L. & Hawkes, D.J., et al. A method for the comparison of biomechanical breast models, Presented at Workshop on Mathematical Methods in Biomedical Image Analysis, Proceedings IEEE Workshop on Mathematical Methods in Biomedical Image Analysis (MMBIA 2001), .