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Scabia, V. Ayyanan, A. De Martino, F. Agnoletto, A. Battista, L. Laszlo, C. Treboux, A. Zaman, K. Stravodimou, A. Jallut, D. Fiche, M. Bucher, P. Ambrosini, G. Sflomos, G. Brisken, C. (2022). Estrogen receptor positive breast cancers have patient specific hormone sensitivities and rely on progesterone receptor. Nature communications, Vol.13 (1).  show abstract

Sflomos, G. Schipper, K. Koorman, T. Fitzpatrick, A. Oesterreich, S. Lee, A.V. Jonkers, J. Brunton, V.G. Christgen, M. Isacke, C. Derksen, P.W. Brisken, C. (2021). Atlas of Lobular Breast Cancer Models: Challenges and Strategic Directions. Cancers (basel), Vol.13 (21).  show abstract

Brisken, C. Scabia, V. (2020). 90 YEARS OF PROGESTERONE: Progesterone receptor signaling in the normal breast and its implications for cancer. Journal of molecular endocrinology, Vol.65 (1), pp. T81-T94.  show abstract

Koch, C. Kuske, A. Joosse, S.A. Yigit, G. Sflomos, G. Thaler, S. Smit, D.J. Werner, S. Borgmann, K. Gärtner, S. Mossahebi Mohammadi, P. Battista, L. Cayrefourcq, L. Altmüller, J. Salinas-Riester, G. Raithatha, K. Zibat, A. Goy, Y. Ott, L. Bartkowiak, K. Tan, T.Z. Zhou, Q. Speicher, M.R. Müller, V. Gorges, T.M. Jücker, M. Thiery, J.-. Brisken, C. Riethdorf, S. Alix-Panabières, C. Pantel, K. (2020). Characterization of circulating breast cancer cells with tumorigenic and metastatic capacity. Embo molecular medicine, Vol.12 (9), pp. e11908-?.  show abstract

Siersbæk, R. Scabia, V. Nagarajan, S. Chernukhin, I. Papachristou, E.K. Broome, R. Johnston, S.J. Joosten, S.E. Green, A.R. Kumar, S. Jones, J. Omarjee, S. Alvarez-Fernandez, R. Glont, S. Aitken, S.J. Kishore, K. Cheeseman, D. Rakha, E.A. D'Santos, C. Zwart, W. Russell, A. Brisken, C. Carroll, J.S. (2020). IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis. Cancer cell, Vol.38 (3), pp. 412-423.e9.  show abstract

Gagniac, L. Rusidzé, M. Boudou, F. Cagnet, S. Adlanmerini, M. Jeannot, P. Gaide, N. Giton, F. Besson, A. Weyl, A. Gourdy, P. Raymond-Letron, I. Arnal, J.-. Brisken, C. Lenfant, F. (2020). Membrane expression of the estrogen receptor ERα is required for intercellular communications in the mammary epithelium. Development (cambridge, england), Vol.147 (5).  show abstract

Cartaxo, A.L. Estrada, M.F. Domenici, G. Roque, R. Silva, F. Gualda, E.J. Loza-Alvarez, P. Sflomos, G. Brisken, C. Alves, P.M. André, S. Brito, C. (2020). A novel culture method that sustains ERα signaling in human breast cancer tissue microstructures. Journal of experimental & clinical cancer research : cr, Vol.39 (1), pp. 161-?.  show abstract

Ataca, D. Aouad, P. Constantin, C. Laszlo, C. Beleut, M. Shamseddin, M. Rajaram, R.D. Jeitziner, R. Mead, T.J. Caikovski, M. Bucher, P. Ambrosini, G. Apte, S.S. Brisken, C. (2020). The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche. Nature communications, Vol.11 (1), pp. 1571-?.  show abstract

Fiche, M. Scabia, V. Aouad, P. Battista, L. Treboux, A. Stravodimou, A. Zaman, K. RLS, Dormoy, V. Ayyanan, A. Sflomos, G. Brisken, C. (2019). Intraductal patient-derived xenografts of estrogen receptor α-positive breast cancer recapitulate the histopathological spectrum and metastatic potential of human lesions. The journal of pathology, Vol.247 (3), pp. 287-292.  show abstract

Nacht, A.S. Ferrari, R. Zaurin, R. Scabia, V. Carbonell-Caballero, J. Le Dily, F. Quilez, J. Leopoldi, A. Brisken, C. Beato, M. Vicent, G.P. (2019). C/EBPα mediates the growth inhibitory effect of progestins on breast cancer cells. The embo journal, Vol.38 (18), pp. e101426-?.  show abstract

Laszlo, C.F. Paz Montoya, J. Shamseddin, M. De Martino, F. Beguin, A. Nellen, R. Bruce, S.J. Moniatte, M. Henry, H. Brisken, C. (2019). A high resolution LC-MS targeted method for the concomitant analysis of 11 contraceptive progestins and 4 steroids. Journal of pharmaceutical and biomedical analysis, Vol.175, pp. 112756-?.  show abstract

Jeitziner, R. Carriere, M. Rougemont, J. Oudot, S. Hess, K. Brisken, C. (2019). Two-Tier Mapper, an unbiased topology-based clustering method for enhanced global gene expression analysis. Bioinformatics, Vol.35, pp. 3339-3347.  show abstract

Ozdemir, B.C. Sflomos, G. Brisken, C. (2018). The challenges of modeling hormone receptor-positive breast cancer in mice. Endocrine-related cancer, Vol.25, pp. R319-R330.  show abstract

Cagnet, S. Ataca, D. Sflomos, G. Aouad, P. Schuepbach-Mallepell, S. Hugues, H. Krust, A. Ayyanan, A. Scabia, V. Brisken, C. (2018). Oestrogen receptor α AF-1 and AF-2 domains have cell population-specific functions in the mammary epithelium. Nature communications, Vol.9 (1), pp. 4723-?.  show abstract

Buric, D. Brisken, C. (2017). Analysis of Mammary Gland Phenotypes by Transplantation of the Genetically Marked Mammary Epithelium. , , pp. 115-129.

Dobrolecki, L.E. Airhart, S.D. Alferez, D.G. Aparicio, S. Behbod, F. Bentires-Alj, M. Brisken, C. Bult, C.J. Cai, S. Clarke, R.B. Dowst, H. Ellis, M.J. Gonzalez-Suarez, E. Iggo, R.D. Kabos, P. Li, S. Lindeman, G.J. Marangoni, E. McCoy, A. Meric-Bernstam, F. Piwnica-Worms, H. Poupon, M.-. Reis-Filho, J. Sartorius, C.A. Scabia, V. Sflomos, G. Tu, Y. Vaillant, F. Visvader, J.E. Welm, A. Wicha, M.S. Lewis, M.T. (2016). Patient-derived xenograft (PDX) models in basic and translational breast cancer research. Cancer and metastasis reviews, Vol.35, pp. 547-573.  show abstract

Sflomos, G. Dormoy, V. Metsalu, T. Jeitziner, R. Battista, L. Scabia, V. Raffoul, W. Delaloye, J.-. Treboux, A. Fiche, M. Vilo, J. Ayyanan, A. Brisken, C. (2016). A Preclinical Model for ER alpha-Positive Breast Cancer Points to the Epithelial Microenvironment as Determinant of Luminal Phenotype and Hormone Response. Cancer cell, Vol.29, pp. 407-422.  show abstract

Ataca, D. Caikovski, M. Piersigilli, A. Moulin, A. Benarafa, C. Earp, S.E. Guri, Y. Kostic, C. Arsenivic, Y. Soininen, R. Apte, S.S. Brisken, C. (2016). Adamts18 deletion results in distinct developmental defects and provides a model for congenital disorders of lens, lung, and female reproductive tract development. Biology open, Vol.5, pp. 1585-1594.  show abstract

Sflomos, G. Shamseddin, M. Brisken, C. (2015). An Ex vivo Model to Study Hormone Action in the Human Breast. Jove-journal of visualized experiments, .  show abstract

Blom, S. Wang, Y. Metsalu, T. Vesterinen, T. Pellinen, T. Grote, A. Linder, N. Saila, J. Valimaki, K. Kovanen, R.-. Monni, O. Kovanen, P. Davies, E. Stock, K. Estrada, M. Sflomos, G. Gruenewald, S. Brito, C. Schueler, J. de Hoogt, R. Brisken, C. van der Kuip, H. van Weerden, W. Barry, S. Sommergruber, W. Anderson, E. Nees, M. Klefstrom, J. Vilo, J. Verschuren, E. Graeser, R. Hickman, J. Lundin, J. Kallioniemi, O. (2015). Systems pathology for characterization of cancer model systems in a multicenter IMI-PREDECT project. Cancer research, Vol.75.

Rajaram, R.D. Buric, D. Caikovski, M. Ayyanan, A. Rougemont, J. Shan, J. Vainio, S.J. Yalcin-Ozuysal, O. Brisken, C. (2015). Progesterone and Wnt4 control mammary stem cells via myoepithelial crosstalk. Embo journal, Vol.34, pp. 641-652.  show abstract

Procopio, M.-. Laszlo, C. Al Labban, D. Kim, D.E. Bordignon, P. Jo, S.-. Goruppi, S. Menietti, E. Stall, P. Ala, U. Provero, P. Hoetzenecker, W. Neel, V. Kilarski, W.W. Swartz, M.A. Brisken, C. Lefort, K. Dotto, G.P. (2015). Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation (vol 17, pg 1193, 2015). Nature cell biology, Vol.17.

Brisken, C. Hess, K. Jeitziner, R. (2015). Progesterone and Overlooked Endocrine Pathways in Breast Cancer Pathogenesis. Endocrinology, Vol.156, pp. 3442-3450.  show abstract

Cimino, D. De Pitta, C. Orso, F. Zampini, M. Casara, S. Penna, E. Quaglino, E. Forni, M. Damasco, C. Pinatel, E. Ponzone, R. Romualdi, C. Brisken, C. De Bortoli, M. Biglia, N. Provero, P. Lanfranchi, G. Taverna, D. (2013). miR148b is a major coordinator of breast cancer progression in a relapse-associated microRNA signature by targeting ITGA5, ROCK1, PIK3CA, NRAS, and CSF1. Faseb journal, Vol.27, pp. 1223-1235.  show abstract

Brisken, C. (2013). Progesterone signalling in breast cancer: a neglected hormone coming into the limelight. Nature reviews cancer, Vol.13, pp. 385-396.  show abstract

Soto, A.M. Brisken, C. Schaeberle, C. Sonnenschein, C. (2013). Does Cancer Start in the Womb? Altered Mammary Gland Development and Predisposition to Breast Cancer due to in Utero Exposure to Endocrine Disruptors. Journal of mammary gland biology and neoplasia, Vol.18, pp. 199-208.  show abstract

Tanos, T. Sflomos, G. Echeverria, P.C. Ayyanan, A. Gutierrez, M. Delaloye, J.-. Raffoul, W. Fiche, M. Dougall, W. Schneider, P. Yalcin-Ozuysal, O. Brisken, C. (2013). Progesterone/RANKL Is a Major Regulatory Axis in the Human Breast. Science translational medicine, Vol.5.  show abstract

Rajaram, R.D. Brisken, C. (2012). Paracrine signaling by progesterone. Molecular and cellular endocrinology, Vol.357, pp. 80-90.  show abstract

Tanos, T. Rojo, L.J. Echeverria, P. Brisken, C. (2012). ER and PR signaling nodes during mammary gland development. Breast cancer research, Vol.14.  show abstract

Dong, J. Huang, S. Caikovski, M. Ji, S. McGrath, A. Custorio, M.G. Creighton, C.J. Maliakkal, P. Bogoslovskaia, E. Du, Z. Zhang, X. Lewis, M.T. Sablitzky, F. Brisken, C. Li, Y. (2011). ID4 regulates mammary gland development by suppressing p38MAPK activity. Development, Vol.138, pp. 5247-5256.  show abstract

Ayyanan, A. Laribi, O. Schuepbach-Mallepell, S. Schrick, C. Gutierrez, M. Tanos, T. Lefebvre, G. Rougemont, J. Yalcin-Ozuysal, O. Brisken, C. (2011). Perinatal Exposure to Bisphenol A Increases Adult Mammary Gland Progesterone Response and Cell Number. Molecular endocrinology, Vol.25, pp. 1915-1923.  show abstract

Booth, B.W. Boulanger, C.A. Anderson, L.H. Jimenez-Rojo, L. Brisken, C. Smith, G.H. (2010). Amphiregulin mediates self-renewal in an immortal mammary epithelial cell line with stem cell characteristics. Experimental cell research, Vol.316, pp. 422-432.  show abstract

Dietrich, C. Weiss, C. Bockamp, E. Brisken, C. Roskams, T. Morris, R. Oesch-Bartlomowicz, B. Oesch, F. (2010). Stem cells in chemical carcinogenesis. Archives of toxicology, Vol.84 (3), pp. 245-251.

Battula, V.L. Evans, K.W. Hollier, B.G. Shi, Y. Marini, F.C. Ayyanan, A. Wang, R.-. Brisken, C. Guerra, R. Andreeff, M. Mani, S.A. (2010). Epithelial-Mesenchymal Transition-Derived Cells Exhibit Multilineage Differentiation Potential Similar to Mesenchymal Stem Cells. Stem cells, Vol.28, pp. 1435-1445.  show abstract

Yalcin-Ozuysal, Ö. Fiche, M. Guitierrez, M. Wagner, K.-. Raffoul, W. Brisken, C. (2010). Antagonistic roles of Notch and p63 in controlling mammary epithelial cell fates. Cell death & differentiation, Vol.17 (10), pp. 1600-1612.

Brisken, C. O’Malley, B. (2010). Hormone Action in the Mammary Gland. Cold spring harbor perspectives in biology, Vol.2.  show abstract

Hu, B. Lefort, K. Qiu, W. Nguyen, B.-. Rajaram, R.D. Castillo, E. He, F. Chen, Y. Angel, P. Brisken, C. Dotto, G.P. (2010). Control of hair follicle cell fate by underlying mesenchyme through a CSL-Wnt5a-FoxN1 regulatory axis. Genes & development, Vol.24, pp. 1519-1532.  show abstract

Yang, C. Chen, L. Li, C. Lynch, M.C. Brisken, C. Schmidt, E.V. (2010). Cyclin D1 Enhances the Response to Estrogen and Progesterone by Regulating Progesterone Receptor Expression. Molecular and cellular biology, Vol.30, pp. 3111-3125.  show abstract

Beleut, M. Rajaram, R.D. Caikovski, M. Ayyanan, A. Germano, D. Choi, Y. Schneider, P. Brisken, C. (2010). Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland. Proceedings of the national academy of sciences of the united states of america, Vol.107, pp. 2989-2994.  show abstract

Cicalese, A. Bonizzi, G. Pasi, C.E. Faretta, M. Ronzoni, S. Giulini, B. Brisken, C. Minucci, S. Di Fiore, P.P. Pelicci, P.G. (2009). The Tumor Suppressor p53 Regulates Polarity of Self-Renewing Divisions in Mammary Stem Cells. Cell, Vol.138, pp. 1083-1095.  show abstract

Yalcin-Ozuysal, O. Brisken, C. (2009). From normal cell types to malignant phenotypes. Breast cancer research, Vol.11.  show abstract

Barbaroux, J.-. Beleut, M. Brisken, C. Mueller, C.G. Groves, R.W. (2008). Epidermal receptor activator of NF-kappa B ligand controls Langerhans cells numbers and proliferation. Journal of immunology, Vol.181, pp. 1103-1108.  show abstract

Boulay, A. Breuleux, M. Stephan, C. Fux, C. Brisken, C. Fiche, M. Wartmann, M. Stumm, M. Lane, H.A. Hynes, N.E. (2008). The Ret receptor tyrosine kinase pathway functionally interacts with the ER alpha pathway in breast cancer. Cancer research, Vol.68, pp. 3743-3751.  show abstract

Mani, S.A. Guo, W. Liao, M.-. Eaton, E.N. Ayyanan, A. Zhou, A.Y. Brooks, M. Reinhard, F. Zhang, C.C. Shipitsin, M. Campbell, L.L. Polyak, K. Brisken, C. Yang, J. Weinberg, R.A. (2008). The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell, Vol.133, pp. 704-715.  show abstract

Tanos, T. Brisken, C. (2008). What Signals Operate in the Mammary Niche?. Breast disease, Vol.29 (1), pp. 69-82.

Brisken, C. (2008). Endocrine disruptors and breast cancer. Chimia, Vol.62, pp. 406-409.  show abstract

Brisken, C. Duss, S. (2007). Stem Cells and the Stem Cell Niche in the Breast: An Integrated Hormonal and Developmental Perspective. Stem cell reviews, Vol.3 (2), pp. 147-156.

Ciarloni, L. Mallepell, S. Brisken, C. (2007). Amphiregulin is an essential mediator of estrogen receptor alpha function in mammary gland development. Proceedings of the national academy of sciences of the united states of america, Vol.104, pp. 5455-5460.  show abstract

Duss, S. Andre, S. Nicoulaz, A.-. Fiche, M. Bonnefoi, H. Brisken, C. Iggo, R.D. (2007). An oestrogen-dependent model of breast cancer created by transformation of normal human mammary epithelial cells. Breast cancer research, Vol.9.  show abstract

Brisken, C. Rajaram, R.D. (2006). Alveolar and Lactogenic Differentiation. Journal of mammary gland biology and neoplasia, Vol.11 (3-4), pp. 239-248.

Ayyanan, A. Civenni, G. Ciarloni, L. Morel, C. Mueller, N. Lefort, K. Mandinova, A. Raffoul, W. Fiche, M. Dotto, G.P. Brisken, C. (2006). Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism. Proceedings of the national academy of sciences, Vol.103 (10), pp. 3799-3804.  show abstract

Mallepell, S. Krust, A. Chambon, P. Brisken, C. (2006). Paracrine signaling through the epithelial estrogen receptor α is required for proliferation and morphogenesis in the mammary gland. Proceedings of the national academy of sciences, Vol.103 (7), pp. 2196-2201.  show abstract

Farmer, P. Bonnefoi, H. Becette, V. Tubiana-Hulin, M. Fumoleau, P. Larsimont, D. MacGrogan, G. Bergh, J. Cameron, D. Goldstein, D. Duss, S. Nicoulaz, A.-. Brisken, C. Fiche, M. Delorenzi, M. Iggo, R. (2005). Identification of molecular apocrine breast tumours by microarray analysis. Oncogene, Vol.24 (29), pp. 4660-4671.

Devgan, V. Mammucari, C. Millar, S.E. Brisken, C. Dotto, G.P. (2005). p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation. Genes & development, Vol.19 (12), pp. 1485-1495.  show abstract

Chu, E.Y. Hens, J. Andl, T. Kairo, A. Yamaguchi, T.P. Brisken, C. Glick, A. Wysolmerski, J.J. Millar, S.E. (2004). Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis. Development, Vol.131 (19), pp. 4819-4829.  show abstract

Gass, S. Harris, J. Ormandy, C. Brisken, C. (2003). Using Gene Expression Arrays to Elucidate Transcriptional Profiles Underlying Prolactin Function. Journal of mammary gland biology and neoplasia, Vol.8 (3), pp. 269-285.

Brisken, C. Ayyanan, A. Doppler, W. (2002). Prolactin signaling and Stat5: going their own separate ways?. Breast cancer research, Vol.4 (6).

Brisken, C. Ayyannan, A. Nguyen, C. Heineman, A. Reinhardt, F. Jan, T. Dey, S.K. Dotto, G.P. Weinberg, R.A. (2002). IGF-2 Is a Mediator of Prolactin-Induced Morphogenesis in the Breast. Developmental cell, Vol.3 (6), pp. 877-887.

Brisken, C. Socolovsky, M. Lodish, H.F. Weinberg, R. (2002). The signaling domain of the erythropoietin receptor rescues prolactin receptor-mutant mammary epithelium. Proceedings of the national academy of sciences, Vol.99 (22), pp. 14241-14245.  show abstract

Brisken, C. Heineman, A. Chavarria, T. Elenbaas, B. Tan, J. Dey, S.K. McMahon, J.A. McMahon, A.P. Weinberg, R.A. (2000). Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling. Genes & development, Vol.14 (6), pp. 650-5.

Brisken, C. Kaur, S. Chavarria, T.E. Binart, N. Sutherland, R.L. Weinberg, R.A. Kelly, P.A. Ormandy, C.J. (1999). Prolactin Controls Mammary Gland Development via Direct and Indirect Mechanisms. Developmental biology, Vol.210 (1), pp. 96-106.

George, A.L. Boulanger, C.A. Anderson, L.H. Cagnet, S. Brisken, C. Smith, G.H. In vivo reprogramming of non-mammary cells to an epithelial cell fate is independent of amphiregulin signaling. Journal of cell science, Vol.130 (12), pp. 2018-2025.  show abstract

Brisken, C. Ataca, D. Endocrine hormones and local signals during the development of the mouse mammary gland. Wiley interdisciplinary reviews-developmental biology, Vol.4, pp. 181-195.  show abstract

Sflomos, G. Battista, L. Aouad, P. De Martino, F. Scabia, V. Stravodimou, A. Ayyanan, A. Ifticene-Treboux, A. RLS, Bucher, P. Fiche, M. Ambrosini, G. Brisken, C. Intraductal xenografts show lobular carcinoma cells rely on their own extracellular matrix and LOXL1. Embo molecular medicine, Vol.13 (3), pp. e13180-?.  show abstract

Shamseddin, M. De Martino, F. Constantin, C. Scabia, V. Lancelot, A.-. Laszlo, C. Ayyannan, A. Battista, L. Raffoul, W. Gailloud-Matthieu, M.-. Bucher, P. Fiche, M. Ambrosini, G. Sflomos, G. Brisken, C. Contraceptive progestins with androgenic properties stimulate breast epithelial cell proliferation. Embo molecular medicine, Vol.13 (7), pp. e14314-?.  show abstract

Juppet, Q. De Martino, F. Marcandalli, E. Weigert, M. Burri, O. Unser, M. Brisken, C. Sage, D. Deep Learning Enables Individual Xenograft Cell Classification in Histological Images by Analysis of Contextual Features. Journal of mammary gland biology and neoplasia, Vol.26 (2), pp. 101-112.  show abstract


Conferences

Villiger, M.L.Beleut, M.Brisken, C.Lasser, T.Leitgeb, R.A. (2007). Extended focus Fourier domain optical coherence microscopy assists developmental biology, SPIE; Opt Soc Amer; European Off Aerosp Res & Dev; AF Off Sci Res; USAF Res Lab; European Opt Soc; Wissensch Gesell Lasermed e V; Deutsch Gesell Lasermed e V. OPTICAL COHERENCE TOMOGRAPHY AND COHERENCE TECHNIQUES III, Vol.6627.

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