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Journal Articles

Coker, E.A. Mitsopoulos, C. Tym, J.E. Komianou, A. Kannas, C. Di Micco, P. Villasclaras Fernandez, E. Ozer, B. Antolin, A.A. Workman, P. Al-Lazikani, B. (2019). canSAR: update to the cancer translational research and drug discovery knowledgebase. Nucleic acids research, Vol.47 (D1), pp. D917-D922.  show abstract

Wedge, D.C. Gundem, G. Mitchell, T. Woodcock, D.J. Martincorena, I. Ghori, M. Zamora, J. Butler, A. Whitaker, H. Kote-Jarai, Z. Alexandrov, L.B. Van Loo, P. Massie, C.E. Dentro, S. Warren, A.Y. Verrill, C. Berney, D.M. Dennis, N. Merson, S. Hawkins, S. Howat, W. Lu, Y.-. Lambert, A. Kay, J. Kremeyer, B. Karaszi, K. Luxton, H. Camacho, N. Marsden, L. Edwards, S. Matthews, L. Bo, V. Leongamornlert, D. McLaren, S. Ng, A. Yu, Y. Zhang, H. Dadaev, T. Thomas, S. Easton, D.F. Ahmed, M. Bancroft, E. Fisher, C. Livni, N. Nicol, D. Tavaré, S. Gill, P. Greenman, C. Khoo, V. Van As, N. Kumar, P. Ogden, C. Cahill, D. Thompson, A. Mayer, E. Rowe, E. Dudderidge, T. Gnanapragasam, V. Shah, N.C. Raine, K. Jones, D. Menzies, A. Stebbings, L. Teague, J. Hazell, S. Corbishley, C. CAMCAP Study Group, de Bono, J. Attard, G. Isaacs, W. Visakorpi, T. Fraser, M. Boutros, P.C. Bristow, R.G. Workman, P. Sander, C. TCGA Consortium, Hamdy, F.C. Futreal, A. McDermott, U. Al-Lazikani, B. Lynch, A.G. Bova, G.S. Foster, C.S. Brewer, D.S. Neal, D.E. Cooper, C.S. Eeles, R.A. (2018). Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets. Nature genetics, Vol.50 (5), pp. 682-692.  show abstract

Antolin, A.A. Tym, J.E. Komianou, A. Collins, I. Workman, P. Al-Lazikani, B. (2018). Objective, Quantitative, Data-Driven Assessment of Chemical Probes. Cell chem biol, Vol.25 (2), pp. 194-205.e5.  show abstract

Campbell, J. Ryan, C.J. Brough, R. Bajrami, I. Pemberton, H.N. Chong, I.Y. Costa-Cabral, S. Frankum, J. Gulati, A. Holme, H. Miller, R. Postel-Vinay, S. Rafiq, R. Wei, W. Williamson, C.T. Quigley, D.A. Tym, J. Al-Lazikani, B. Fenton, T. Natrajan, R. Strauss, S.J. Ashworth, A. Lord, C.J. (2016). Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines. Cell reports, Vol.14 (10), pp. 2490-2501.  show abstract

Workman, P. Clarke, P.A. Al-Lazikani, B. (2016). Blocking the survival of the nastiest by HSP90 inhibition. Oncotarget, Vol.7 (4), pp. 3658-3661.

Patel, M.N. Halling-Brown, M.D. Tym, J.E. Workman, P. Al-Lazikani, B. (2013). Objective assessment of cancer genes for drug discovery. Nat rev drug discov, Vol.12 (1), pp. 35-50.  show abstract

Gaulton, A. Bellis, L.J. Bento, A.P. Chambers, J. Davies, M. Hersey, A. Light, Y. McGlinchey, S. Michalovich, D. Al-Lazikani, B. Overington, J.P. (2012). ChEMBL: a large-scale bioactivity database for drug discovery. Nucleic acids res, Vol.40 (Database issue), pp. D1100-D1107.  show abstract

Halling-Brown, M.D. Bulusu, K.C. Patel, M. Tym, J.E. Al-Lazikani, B. (2012). canSAR: an integrated cancer public translational research and drug discovery resource. Nucleic acids res, Vol.40 (Database issue), pp. D947-D956.  show abstract

Al-Lazikani, B. Banerji, U. Workman, P. (2012). Combinatorial drug therapy for cancer in the post-genomic era. Nat biotechnol, Vol.30 (7), pp. 679-692.  show abstract

Berriman, M. Haas, B.J. LoVerde, P.T. Wilson, R.A. Dillon, G.P. Cerqueira, G.C. Mashiyama, S.T. Al-Lazikani, B. Andrade, L.F. Ashton, P.D. Aslett, M.A. Bartholomeu, D.C. Blandin, G. Caffrey, C.R. Coghlan, A. Coulson, R. Day, T.A. Delcher, A. DeMarco, R. Djikeng, A. Eyre, T. Gamble, J.A. Ghedin, E. Gu, Y. Hertz-Fowler, C. Hirai, H. Hirai, Y. Houston, R. Ivens, A. Johnston, D.A. Lacerda, D. Macedo, C.D. McVeigh, P. Ning, Z. Oliveira, G. Overington, J.P. Parkhill, J. Pertea, M. Pierce, R.J. Protasio, A.V. Quail, M.A. Rajandream, M.-. Rogers, J. Sajid, M. Salzberg, S.L. Stanke, M. Tivey, A.R. White, O. Williams, D.L. Wortman, J. Wu, W. Zamanian, M. Zerlotini, A. Fraser-Liggett, C.M. Barrell, B.G. El-Sayed, N.M. (2009). The genome of the blood fluke Schistosoma mansoni. Nature, Vol.460 (7253), pp. 352-358.  show abstract

Agüero, F. Al-Lazikani, B. Aslett, M. Berriman, M. Buckner, F.S. Campbell, R.K. Carmona, S. Carruthers, I.M. Chan, A.W. Chen, F. Crowther, G.J. Doyle, M.A. Hertz-Fowler, C. Hopkins, A.L. McAllister, G. Nwaka, S. Overington, J.P. Pain, A. Paolini, G.V. Pieper, U. Ralph, S.A. Riechers, A. Roos, D.S. Sali, A. Shanmugam, D. Suzuki, T. Van Voorhis, W.C. Verlinde, C.L. (2008). Genomic-scale prioritization of drug targets: the TDR Targets database. Nat rev drug discov, Vol.7 (11), pp. 900-907.  show abstract

Overington, J.P. Al-Lazikani, B. Hopkins, A.L. (2006). How many drug targets are there?. Nat rev drug discov, Vol.5 (12), pp. 993-996.  show abstract

Santos, R. Ursu, O. Gaulton, A. Bento, A.P. Donadi, R.S. Bologa, C.G. Karlsson, A. Al-Lazikani, B. Hersey, A. Oprea, T.I. Overington, J.P. A comprehensive map of molecular drug targets. Nat rev drug discov, Vol.16 (1), pp. 19-34.  show abstract

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