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Spiteri, I., Caravagna, G., Cresswell, G.D., Vatsiou, A., Nichol, D., Acar, A., Ermini, L., Chkhaidze, K., Werner, B., Mair, R., et al. (2019). Evolutionary dynamics of residual disease in human glioblastoma. Ann oncol, Vol.30 (3), pp. 456-463.  show abstract

Turajlic, S., Sottoriva, A., Graham, T. & Swanton, C. (2019). Resolving genetic heterogeneity in cancer. Nat rev genet, Vol.20 (7), pp. 404-416.  show abstract

Williams, M.J., Sottoriva, A. & Graham, T.A. (2019). Measuring Clonal Evolution in Cancer with Genomics. Annu rev genomics hum genet, Vol.20, pp. 309-329.  show abstract

Williams, M.J., Werner, B., Barnes, C.P., Graham, T.A. & Sottoriva, A. (2018). Reply: Is the evolution of tumors Darwinian or non-Darwinian?. National science review, Vol.5 (1), pp. 17-19.

Sottoriva, A. (2018). Divergent adaptation in thyroid cancers. Ann oncol, Vol.29 (6), pp. 1353-1353.

Barry, P., Vatsiou, A., Spiteri, I., Nichol, D., Cresswell, G.D., Acar, A., Trahearn, N., Hrebien, S., Garcia-Murillas, I., Chkhaidze, K., et al. (2018). The Spatiotemporal Evolution of Lymph Node Spread in Early Breast Cancer. Clinical cancer research, Vol.24 (19), pp. 4763-4770.

Cross, W., Kovac, M., Mustonen, V., Temko, D., Davis, H., Baker, A.-., Biswas, S., Arnold, R., Chegwidden, L., Gatenbee, C., et al. (2018). The evolutionary landscape of colorectal tumorigenesis. Nature ecology & evolution, Vol.2 (10), pp. 1661-1672.

Heindl, A., Khan, A.M., Rodrigues, D.N., Eason, K., Sadanandam, A., Orbegoso, C., Punta, M., Sottoriva, A., Lise, S., Banerjee, S., et al. (2018). Microenvironmental niche divergence shapes BRCA1-dysregulated ovarian cancer morphological plasticity. Nature communications, Vol.9 (1).

Heide, T., Zapata, L., Williams, M.J., Werner, B., Caravagna, G., Barnes, C.P., Graham, T.A. & Sottoriva, A. (2018). Reply to 'Neutral tumor evolution?'. Nat genet, Vol.50 (12), pp. 1633-1637.

Williams, M.J., Werner, B., Heide, T., Barnes, C.P., Graham, T.A. & Sottoriva, A. (2018). Reply to 'Revisiting signatures of neutral tumor evolution in the light of complexity of cancer genomic data'. Nat genet, Vol.50 (12), pp. 1628-1630.

Graham, T.A. & Sottoriva, A. (2017). Measuring cancer evolution from the genome. The journal of pathology, Vol.241 (2), pp. 183-191.

Sottoriva, A., Barnes, C.P. & Graham, T.A. (2017). Catch my drift? Making sense of genomic intra-tumour heterogeneity. Biochimica et biophysica acta (bba) - reviews on cancer, Vol.1867 (2), pp. 95-100.

Maley, C.C., Aktipis, A., Graham, T.A., Sottoriva, A., Boddy, A.M., Janiszewska, M., Silva, A.S., Gerlinger, M., Yuan, Y., Pienta, K.J., et al. (2017). Classifying the evolutionary and ecological features of neoplasms. Nat rev cancer, Vol.17 (10), pp. 605-619.  show abstract

Baker, A.-., Huang, W., Wang, X.-., Jansen, M., Ma, X.-., Kim, J., Anderson, C.M., Wu, X., Pan, L., Su, N., et al. (2017). Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution. Nature communications, Vol.8 (1).

Williams, M.J., Werner, B., Barnes, C.P., Graham, T.A. & Sottoriva, A. (2017). Reply: Uncertainties in tumor allele frequencies limit power to infer evolutionary pressures. Nat genet, Vol.49 (9), pp. 1289-1291.

Werner, B., Scott, J.G., Sottoriva, A., Anderson, A.R., Traulsen, A. & Altrock, P.M. (2016). The Cancer Stem Cell Fraction in Hierarchically Organized Tumors Can Be Estimated Using Mathematical Modeling and Patient-Specific Treatment Trajectories. Cancer research, Vol.76 (7), pp. 1705-1713.

Williams, M.J., Werner, B., Barnes, C.P., Graham, T.A. & Sottoriva, A. (2016). Identification of neutral tumor evolution across cancer types. Nature genetics, Vol.48 (3), pp. 238-244.

Williams, M.J., Werner, B., Graham, T.A. & Sottoriva, A. (2016). Functional versus non-functional intratumor heterogeneity in cancer. Molecular & cellular oncology, Vol.3 (4), pp. e1162897-e1162897.

Eskilsson, E., Rosland, G.V., Talasila, K.M., Knappskog, S., Keunen, O., Sottoriva, A., Foerster, S., Solecki, G., Taxt, T., Jirik, R., et al. (2016). EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation. Neuro-oncology, Vol.18 (12), pp. 1644-1655.

Lipinski, K.A., Barber, L.J., Davies, M.N., Ashenden, M., Sottoriva, A. & Gerlinger, M. (2016). Cancer Evolution and the Limits of Predictability in Precision Cancer Medicine. Trends in cancer, Vol.2 (1), pp. 49-63.  show abstract

Piccirillo, S.G., Spiteri, I., Sottoriva, A., Touloumis, A., Ber, S., Price, S.J., Heywood, R., Francis, N.-., Howarth, K.D., Collins, V.P., et al. (2015). Contributions to drug resistance in glioblastoma derived from malignant cells in the sub-ependymal zone. Cancer res, Vol.75 (1), pp. 194-202.  show abstract

Sottoriva, A., Kang, H., Ma, Z., Graham, T.A., Salomon, M.P., Zhao, J., Marjoram, P., Siegmund, K., Press, M.F., Shibata, D., et al. (2015). A Big Bang model of human colorectal tumor growth. Nat genet, Vol.47 (3), pp. 209-216.  show abstract

Gubernator, M., Slater, S.C., Spencer, H.L., Spiteri, I., Sottoriva, A., Riu, F., Rowlinson, J., Avolio, E., Katare, R., Mangialardi, G., et al. (2015). Epigenetic profile of human adventitial progenitor cells correlates with therapeutic outcomes in a mouse model of limb ischemia. Arterioscler thromb vasc biol, Vol.35 (3), pp. 675-688.  show abstract

Kang, H., Salomon, M.P., Sottoriva, A., Zhao, J., Toy, M., Press, M.F., Curtis, C., Marjoram, P., Siegmund, K. & Shibata, D., et al. (2015). Many private mutations originate from the first few divisions of a human colorectal adenoma. The journal of pathology, Vol.237 (3), pp. 355-362.

Sottoriva, A., Spiteri, I., Shibata, D., Curtis, C. & Tavaré, S. (2013). Single-molecule genomic data delineate patient-specific tumor profiles and cancer stem cell organization. Cancer res, Vol.73 (1), pp. 41-49.  show abstract

Sottoriva, A., Spiteri, I., Piccirillo, S.G., Touloumis, A., Collins, V.P., Marioni, J.C., Curtis, C., Watts, C. & Tavaré, S. (2013). Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics. Proc natl acad sci u s a, Vol.110 (10), pp. 4009-4014.  show abstract

Dvinge, H., Git, A., Gräf, S., Salmon-Divon, M., Curtis, C., Sottoriva, A., Zhao, Y., Hirst, M., Armisen, J., Miska, E.A., et al. (2013). The shaping and functional consequences of the microRNA landscape in breast cancer. Nature, Vol.497 (7449), pp. 378-382.  show abstract

Vermeulen, L., Morrissey, E., van der Heijden, M., Nicholson, A.M., Sottoriva, A., Buczacki, S., Kemp, R., Tavaré, S. & Winton, D.J. (2013). Defining stem cell dynamics in models of intestinal tumor initiation. Science, Vol.342 (6161), pp. 995-998.  show abstract

Ageron, M., Aguilar, J.A., Al Samarai, I., Albert, A., Ameli, F., André, M., Anghinolfi, M., Anton, G., Anvar, S., Ardid, M., et al. (2011). ANTARES: The first undersea neutrino telescope. Nuclear instruments and methods in physics research section a: accelerators, spectrometers, detectors and associated equipment, Vol.656, pp. 11-38.  show abstract

Sottoriva, A., Vermeulen, L. & Tavaré, S. (2011). Modeling Evolutionary Dynamics of Epigenetic Mutations in Hierarchically Organized Tumors. Plos computational biology, Vol.7.

Sottoriva, A., Verhoeff, J.J., Borovski, T., McWeeney, S.K., Naumov, L., Medema, J.P., Sloot, P.M. & Vermeulen, L. (2010). Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity. Cancer res, Vol.70 (1), pp. 46-56.  show abstract

Sottoriva, A., Sloot, P.M., Medema, J.P. & Vermeulen, L. (2010). Exploring cancer stem cell niche directed tumor growth. Cell cycle, Vol.9 (8), pp. 1472-1479.  show abstract

Sottoriva, A. & Tavaré, S. (2010). Integrating approximate Bayesian computation with complex agent-based models for cancer research. Compstat 2010 - proceedings in computational statistics, eds. saporta g & lechevallier y. springer, physica verlag, , pp. 57-66.

Portegies Zwart, S., McMillan, S., Harfst, S., Groen, D., Fujii, M., Nualláin, B.Ó., Glebbeek, E., Heggie, D., Lombardi, J., Hut, P., et al. (2009). A multiphysics and multiscale software environment for modeling astrophysical systems. New astronomy, Vol.14, pp. 369-378.  show abstract

Piccirillo, S.G., Sottoriva, A. & Watts, C. The role of sub-ventricular zone in gliomagenesis. Aging, Vol.7 (10), pp. 738-739.

Ellis, H.P., Greenslade, M., Powell, B., Spiteri, I., Sottoriva, A. & Kurian, K.M. Current Challenges in Glioblastoma: Intratumour Heterogeneity, Residual Disease, and Models to Predict Disease Recurrence. Frontiers in oncology, Vol.5.

Lote, H., Spiteri Sagastume, I., Ermini, L., Vatsiou, A., Roy, A., McDonald, A., Maka, N., Balsitis, M., Bose, N., Simbolo, M., et al. Carbon dating cancer: defining the chronology of metastatic progression in colorectal cancer. Annals of oncology, .

Vlachogiannis, G., Hedayat, S., Vatsiou, A., Jamin, Y., Fernandez Mateos, J., Khan, K., Lampis, A., Eason, K., Burke, R., Rata, M., et al. Patient-derived organoids model treatment response of metastatic gastrointestinal cancers. Science, .

Williams, M., Werner, B., Heide, T., Curtis, C., Sottoriva, A., Barnes, C.P. & Graham, T.A. Quantification of subclonal selection in cancer from bulk sequencing data. Nature genetics, .

Werner, B. & Sottoriva, A. Variation of mutational burden in healthy human tissues suggests non-random strand segregation and allows measuring somatic mutation rates. Plos computational biology, .

Barry, P., Vatsiou, A., Spiteri Sagastume, I., Nichol, D., Cresswell, G., Acar, A., Trahearn, N., Hrebien, S., Garcia-Murillas, I., Chkhaidze, K., et al. The spatio-temporal evolution of lymph node spread in early breast cancer. Clinical cancer research, .

Khan, K., Cunningham, D., Werner, B., Vlachogiannis, G., Spiteri Sagastume, I., Heide, T., Fernandez Mateos, J., Vatsiou, A., Lampis, A., Damavandi, M.D., et al. Longitudinal liquid biopsy and mathematical modelling of clonal evolution forecast waiting time to treatment failure in the PROSPECT-C phase II colorectal cancer clinical trial. Cancer discovery, .

Caravagna, G., Giarratano, Y., Ramazzotti, D., Tomlinson, I., Graham, T.A., Sanguinetti, G. & Sottoriva, A. Detecting repeated cancer evolution from multiregion tumor sequencing data. Nature methods, .

Sottoriva, A., Chkhaidze, K., Heide, T., Werner, B., Williams, M.J., Huang, W., Caravagna, G. & Graham, T.A. Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data. Plos computational biology, .

Sun, R., Hu, Z., Sottoriva, A., Graham, T.A., Harpak, A., Ma, Z., Fisher, J.M., Shibata, D. & Curtis, C. Between-Region Genetic Divergence Reflects the Mode and Tempo of Tumor Evolution. Nature genetics, .

Werner, B., Traulsen, A., Sottoriva, A. & Dingli, D. Detecting truly clonal alterations from multi-region profiling of tumours. Scientific reports, .

Loupakis, F., Depetris, I., Biason, P., Intini, R., Prete, A.A., Leone, F., Lombardi, P., Filippi, R., Spallanzani, A., Cascinu, S., et al. Prediction of Benefit from Checkpoint Inhibitors in Mismatch Repair Deficient Metastatic Colorectal Cancer: Role of Tumor Infiltrating Lymphocytes. The oncologist, .