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Innocenti, P., Woodward, H.L., Solanki, S., Naud, S., Westwood, I.M., Cronin, N., Hayes, A., Roberts, J., Henley, A.T., Baker, R., et al. (2016). Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle Kinase 1 (MPS1) Using a Structure-Based Hybridization Approach. J med chem, Vol.59 (8), pp. 3671-3688.  show abstract

Drouin, L., McGrath, S., Vidler, L.R., Chaikuad, A., Monteiro, O., Tallant, C., Philpott, M., Rogers, C., Fedorov, O., Liu, M., et al. (2015). Structure enabled design of BAZ2-ICR, a chemical probe targeting the bromodomains of BAZ2A and BAZ2B. J med chem, Vol.58 (5), pp. 2553-2559.  show abstract

Gurden, M.D., Westwood, I.M., Faisal, A., Naud, S., Cheung, K.-., McAndrew, C., Wood, A., Schmitt, J., Boxall, K., Mak, G., et al. (2015). Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance. Cancer research, Vol.75 (16), pp. 3340-3354.

Innocenti, P., Woodward, H., O'Fee, L. & Hoelder, S. (2015). Expanding the scope of fused pyrimidines as kinase inhibitor scaffolds: synthesis and modification of pyrido[3,4-d]pyrimidines. Org biomol chem, Vol.13 (3), pp. 893-904.  show abstract

Vidler, L.R., Filippakopoulos, P., Fedorov, O., Picaud, S., Martin, S., Tomsett, M., Woodward, H., Brown, N., Knapp, S. & Hoelder, S., et al. (2013). Discovery of novel small-molecule inhibitors of BRD4 using structure-based virtual screening. J med chem, Vol.56 (20), pp. 8073-8088.  show abstract

Vidler, L.R., Brown, N., Knapp, S. & Hoelder, S. (2012). Druggability analysis and structural classification of bromodomain acetyl-lysine binding sites. J med chem, Vol.55 (17), pp. 7346-7359.  show abstract

Solanki, S., Innocenti, P., Mas-Droux, C., Boxall, K., Barillari, C., van Montfort, R.L., Aherne, G.W., Bayliss, R. & Hoelder, S. (2011). Benzimidazole inhibitors induce a DFG-out conformation of never in mitosis gene A-related kinase 2 (Nek2) without binding to the back pocket and reveal a nonlinear structure-activity relationship. J med chem, Vol.54 (6), pp. 1626-1639.  show abstract

Whelligan, D.K., Thomson, D.W., Taylor, D. & Hoelder, S. (2010). Two-step synthesis of aza- and diazaindoles from chloroamino-N-heterocycles using ethoxyvinylborolane. J org chem, Vol.75 (1), pp. 11-15.  show abstract

Whelligan, D.K., Solanki, S., Taylor, D., Thomson, D.W., Cheung, K.-., Boxall, K., Mas-Droux, C., Barillari, C., Burns, S., Grummitt, C.G., et al. (2010). Aminopyrazine inhibitors binding to an unusual inactive conformation of the mitotic kinase Nek2: SAR and structural characterization. J med chem, Vol.53 (21), pp. 7682-7698.  show abstract

Richards, M.W., O'Regan, L., Mas-Droux, C., Blot, J.M., Cheung, J., Hoelder, S., Fry, A.M. & Bayliss, R. (2009). An autoinhibitory tyrosine motif in the cell-cycle-regulated Nek7 kinase is released through binding of Nek9. Mol cell, Vol.36 (4), pp. 560-570.  show abstract