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Burns, M.C., Howes, J.E., Sun, Q., Little, A.J., Camper, D.V., Abbott, J.R., Phan, J., Lee, T., Waterson, A.G., Rossanese, O.W., et al. (2018). High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling. Analytical biochemistry, Vol.548, pp. 44-52.

Howes, J.E., Akan, D.T., Burns, M.C., Rossanese, O.W., Waterson, A.G. & Fesik, S.W. (2018). Small Molecule–Mediated Activation of RAS Elicits Biphasic Modulation of Phospho-ERK Levels that Are Regulated through Negative Feedback on SOS1. Molecular cancer therapeutics, Vol.17 (5), pp. 1051-1060.

Hodges, T.R., Abbott, J.R., Little, A.J., Sarkar, D., Salovich, J.M., Howes, J.E., Akan, D.T., Sai, J., Arnold, A.L., Browning, C., et al. (2018). Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS. Journal of medicinal chemistry, Vol.61 (19), pp. 8875-8894.

Wang, F., Jeon, K.O., Salovich, J.M., Macdonald, J.D., Alvarado, J., Gogliotti, R.D., Phan, J., Olejniczak, E.T., Sun, Q., Wang, S., et al. (2018). Discovery of Potent 2-Aryl-6,7-dihydro-5H-pyrrolo[1,2-a]imidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design. Journal of medicinal chemistry, Vol.61 (13), pp. 5623-5642.

Abbott, J.R., Patel, P.A., Howes, J.E., Akan, D.T., Kennedy, J.P., Burns, M.C., Browning, C.F., Sun, Q., Rossanese, O.W., Phan, J., et al. (2018). Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS. Acs medicinal chemistry letters, Vol.9 (9), pp. 941-946.

Shaw, S., Bian, Z., Zhao, B., Tarr, J.C., Veerasamy, N., Jeon, K.O., Belmar, J., Arnold, A.L., Fogarty, S.A., Perry, E., et al. (2018). Optimization of Potent and Selective Tricyclic Indole Diazepinone Myeloid Cell Leukemia-1 Inhibitors Using Structure-Based Design. Journal of medicinal chemistry, Vol.61 (6), pp. 2410-2421.

Abbott, J.R., Hodges, T.R., Daniels, R.N., Patel, P.A., Kennedy, J.P., Howes, J.E., Akan, D.T., Burns, M.C., Sai, J., Sobolik, T., et al. (2018). Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling. Journal of medicinal chemistry, Vol.61 (14), pp. 6002-6017.

Lee, T., Bian, Z., Zhao, B., Hogdal, L.J., Sensintaffar, J.L., Goodwin, C.M., Belmar, J., Shaw, S., Tarr, J.C., Veerasamy, N., et al. (2017). Discovery and biological characterization of potent myeloid cell leukemia-1 inhibitors. Febs letters, Vol.591 (1), pp. 240-251.

Hatch, S.B., Yapp, C., Montenegro, R.C., Savitsky, P., Gamble, V., Tumber, A., Ruda, G.F., Bavetsias, V., Fedorov, O., Atrash, B., et al. (2017). Assessing histone demethylase inhibitors in cells: lessons learned. Epigenetics & chromatin, Vol.10 (1).

Pelz, N.F., Bian, Z., Zhao, B., Shaw, S., Tarr, J.C., Belmar, J., Gregg, C., Camper, D.V., Goodwin, C.M., Arnold, A.L., et al. (2016). Discovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods. Journal of medicinal chemistry, Vol.59 (5), pp. 2054-2066.

Kanu, N., Cerone, M.A., Goh, G., Zalmas, L.-., Bartkova, J., Dietzen, M., McGranahan, N., Rogers, R., Law, E.K., Gromova, I., et al. (2016). DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer. Genome biology, Vol.17 (1).

Patrone, J.D., Pelz, N.F., Bates, B.S., Souza-Fagundes, E.M., Vangamudi, B., Camper, D.V., Kuznetsov, A.G., Browning, C.F., Feldkamp, M.D., Frank, A.O., et al. (2016). Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein A. Chemmedchem, Vol.11 (8), pp. 893-899.

Goodwin, C.M., Rossanese, O.W., Olejniczak, E.T. & Fesik, S.W. (2015). Myeloid cell leukemia-1 is an important apoptotic survival factor in triple-negative breast cancer. Cell death & differentiation, Vol.22 (12), pp. 2098-2106.

Waterson, A.G., Kennedy, J.P., Patrone, J.D., Pelz, N.F., Feldkamp, M.D., Frank, A.O., Vangamudi, B., Souza-Fagundes, E.M., Rossanese, O.W., Chazin, W.J., et al. (2015). Diphenylpyrazoles as Replication Protein A Inhibitors. Acs medicinal chemistry letters, Vol.6 (2), pp. 140-145.

Burke, J.P., Bian, Z., Shaw, S., Zhao, B., Goodwin, C.M., Belmar, J., Browning, C.F., Vigil, D., Friberg, A., Camper, D.V., et al. (2015). Discovery of Tricyclic Indoles That Potently Inhibit Mcl-1 Using Fragment-Based Methods and Structure-Based Design. Journal of medicinal chemistry, Vol.58 (9), pp. 3794-3805.

Bhave, M., Papanikou, E., Iyer, P., Pandya, K., Jain, B.K., Ganguly, A., Sharma, C., Pawar, K., Austin, J., Day, K.J., et al. (2014). Golgi enlargement in Arf-depleted yeast cells is due to altered dynamics of cisternal maturation. Journal of cell science, Vol.127 (1), pp. 250-257.

Burns, M.C., Sun, Q., Daniels, R.N., Camper, D., Kennedy, J.P., Phan, J., Olejniczak, E.T., Lee, T., Waterson, A.G., Rossanese, O.W., et al. (2014). Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange. Proceedings of the national academy of sciences, Vol.111 (9), pp. 3401-3406.

Frank, A.O., Vangamudi, B., Feldkamp, M.D., Souza-Fagundes, E.M., Luzwick, J.W., Cortez, D., Olejniczak, E.T., Waterson, A.G., Rossanese, O.W., Chazin, W.J., et al. (2014). Discovery of a Potent Stapled Helix Peptide That Binds to the 70N Domain of Replication Protein A. Journal of medicinal chemistry, Vol.57 (6), pp. 2455-2461.

Patrone, J.D., Kennedy, J.P., Frank, A.O., Feldkamp, M.D., Vangamudi, B., Pelz, N.F., Rossanese, O.W., Waterson, A.G., Chazin, W.J. & Fesik, S.W., et al. (2013). Discovery of Protein–Protein Interaction Inhibitors of Replication Protein A. Acs medicinal chemistry letters, Vol.4 (7), pp. 601-605.

Rheault, T.R., Stellwagen, J.C., Adjabeng, G.M., Hornberger, K.R., Petrov, K.G., Waterson, A.G., Dickerson, S.H., Mook, R.A., Laquerre, S.G., King, A.J., et al. (2013). Discovery of Dabrafenib: A Selective Inhibitor of Raf Kinases with Antitumor Activity against B-Raf-Driven Tumors. Acs medicinal chemistry letters, Vol.4 (3), pp. 358-362.

Frank, A.O., Feldkamp, M.D., Kennedy, J.P., Waterson, A.G., Pelz, N.F., Patrone, J.D., Vangamudi, B., Camper, D.V., Rossanese, O.W., Chazin, W.J., et al. (2013). Discovery of a Potent Inhibitor of Replication Protein A Protein–Protein Interactions Using a Fragment-Linking Approach. Journal of medicinal chemistry, Vol.56 (22), pp. 9242-9250.

Souza-Fagundes, E.M., Frank, A.O., Feldkamp, M.D., Dorset, D.C., Chazin, W.J., Rossanese, O.W., Olejniczak, E.T. & Fesik, S.W. (2012). A high-throughput fluorescence polarization anisotropy assay for the 70N domain of replication protein A. Analytical biochemistry, Vol.421 (2), pp. 742-749.

Sun, Q., Burke, J.P., Phan, J., Burns, M.C., Olejniczak, E.T., Waterson, A.G., Lee, T., Rossanese, O.W. & Fesik, S.W. (2012). Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-Mediated Activation. Angewandte chemie international edition, Vol.51 (25), pp. 6140-6143.

Stellwagen, J.C., Adjabeng, G.M., Arnone, M.R., Dickerson, S.H., Han, C., Hornberger, K.R., King, A.J., Mook, R.A., Petrov, K.G., Rheault, T.R., et al. (2011). Development of potent B-RafV600E inhibitors containing an arylsulfonamide headgroup. Bioorganic & medicinal chemistry letters, Vol.21 (15), pp. 4436-4440.

Losev, E., Papanikou, E., Rossanese, O.W. & Glick, B.S. (2008). Cdc1p Is an Endoplasmic Reticulum-Localized Putative Lipid Phosphatase That Affects Golgi Inheritance and Actin Polarization by Activating Ca2+ Signaling. Molecular and cellular biology, Vol.28 (10), pp. 3336-3343.

Patel, J.C., Rossanese, O.W. & Galán, J.E. (2005). The functional interface between Salmonella and its host cell: opportunities for therapeutic intervention. Trends in pharmacological sciences, Vol.26 (11), pp. 564-570.

Rossanese, O.W. & Glick, B.S. (2001). Deconstructing Golgi Inheritance. Traffic, Vol.2 (9), pp. 589-596.

ROSSANESE, O.W. (2001). A role for actin, Cdc1p, and Myo2p in the inheritance of late Golgi elements in Saccharomyces cerevisiae. J. cell biol., Vol.153, pp. 47-62.

ROSSANESE, O.W. (1999). Golgi structure correlated wtih transitional endoplasmic reticulum organization in Pichia pastoris and Saccharomyces cerevisiae. J. cell biol., Vol.145, pp. 69-81.

Séron, K., Tieaho, V., Prescianotto-Baschong, C., Aust, T., Blondel, M.-., Guillaud, P., Devilliers, G., Rossanese, O.W., Glick, B.S., Riezman, H., et al. (1998). A Yeast t-SNARE Involved in Endocytosis. Molecular biology of the cell, Vol.9 (10), pp. 2873-2889.  show abstract

Sears, I.B., O'Connor, J., Rossanese, O.W. & Glick, B.S. (1998). A versatile set of vectors for constitutive and regulated gene expression inPichia pastoris. Yeast, Vol.14 (8), pp. 783-790.

Jiang, X., Rossanese, O.W., Brown, N.F., Kujat-Choy, S., Galán, J.E., Finlay, B.B. & Brumell, J.H. The related effector proteins SopD and SopD2 from Salmonella enterica serovar Typhimurium contribute to virulence during systemic infection of mice. Molecular microbiology, Vol.54 (5), pp. 1186-1198.


Conferences

Lee, T., Tarr, J., Zhao, B., Bian, Z., Shaw, S., Belmar, J., Arnold, A., Sensintaffar, J., Moore, W., Stott, G., et al. (2018). Discovery of novel tricyclic Mcl-1 inhibitors that exhibit selective anti-proliferative activity and in vivo efficacy, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol.256.

Waterson, A.G., Kennedy, P., Patrone, J.D., Pelz, N.F., Frank, A.O., Vangamudi, B., Camper, D.V., Souza-Fagundes, E.M., Feldkamp, M.D., Olejniczak, E.T., et al. (2015). Abstract 3695: Discovery of probes to evaluate the disruption of the protein-protein interactions mediated by RPA70N, Presented at Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA, Cancer Chemistry, .

Waterson, A.G., Frank, A.O., Vandgamudi, B., Feldkamp, M.D., Souza-Fagundes, E.M., Luzwick, J.W., Cortez, D., Olejniczak, E.T., Rossanese, O.W., Chazin, W.J., et al. (2014). Abstract 3232: Optimization of a potent stapled helix peptide that binds to Replication Protein A, Presented at Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA, Cancer Chemistry, .

Rossanese, O.W., Burns, M.C., Sun, Q., Daniels, R.N., Camper, D.V., Kennedy, J.P., Phan, J., Olejniczak, E.T., Lee, T., Waterson, A.G., et al. (2014). Abstract 4417: Targeting Ras with small molecules that activate SOS-mediated nucleotide exchange, Presented at Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA, Molecular and Cellular Biology, .

Burns, M., Sun, Q., Daniels, R., Kennedy, J.P., Camper, D., Phan, J., Olejniczak, E., Lee, T., Waterson, A., Rossanese, O., et al. (2013). Abstract PR01: Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange., Presented at Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics--Oct 19-23, 2013; Boston, MA, Protein-Protein Interaction, .

Vangamudi, B., Frank, A.O., Souza-Fagundes, E.M., Feldkamp, M.D., Olejniczak, E.T., Rossanese, O.W. & Fesik, S.W. (2013). Abstract 3340: Stapled helix peptides as probes to evaluate targeted disruption of protein-protein interactions mediated by RPA70N., Presented at Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC, Experimental and Molecular Therapeutics, .

Vangamudi, B., Ayres, A.E., Burke, J.P., Waterson, A.G., Rossanese, O.W. & Fesik, S.W. (2012). Abstract 1813: Evaluation of TBK1 as a novel cancer target in the K-Ras pathway, Presented at Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL, Experimental and Molecular Therapeutics, .

Reinke, C.A., Rossanese, O.W., Bevis, B.J. & Glick, B.S. (2002). Golgi inheritance in Saccharomyces cerevisiae is compromised in an ER inheritance mutant, MOLECULAR BIOLOGY OF THE CELL, Vol.13, p.269A.

Losev, E., Rossanese, O.W. & Glick, B.S. (2002). The predicted phosphoesterase Cdc1p is important for late Golgi inheritance, MOLECULAR BIOLOGY OF THE CELL, Vol.13, p.269A.

Reinke, C.A., Rossanese, O.W., Bevis, B.J. & Glick, B.S. (2000). Genetic analysis of Golgi morphology and inheritance in Saccharomyces cerevisiae., MOLECULAR BIOLOGY OF THE CELL, Vol.11, pp.281A-282A.

Rossanese, O.W. & Glick, B.S. (1998). Genetic analysis of Golgi inheritance in Saccharomyces cerevisiae., MOLECULAR BIOLOGY OF THE CELL, Vol.9, p.223A.

Rossanese, O.W., Soderholm, J., Sears, I.B., Connor, J.O., Williamson, E.K. & Glick, B.S. (1998). Golgi structure correlates with transitional ER organization in budding yeasts., MOLECULAR BIOLOGY OF THE CELL, Vol.9, p.222A.

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