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Parzych, K., Saavedra-García, P., Valbuena, G.N., Al-Sadah, H.A., Robinson, M.E., Penfold, L., Kuzeva, D.M., Ruiz-Tellez, A., Loaiza, S., Holzmann, V., et al. (2019). The coordinated action of VCP/p97 and GCN2 regulates cancer cell metabolism and proteostasis during nutrient limitation. Oncogene, Vol.38 (17), pp. 3216-3231.

Messiou, C., Hillengass, J., Delorme, S., Lecouvet, F.E., Moulopoulos, L.A., Collins, D.J., Blackledge, M.D., Abildgaard, N., Østergaard, B., Schlemmer, H.-., et al. (2019). Guidelines for Acquisition, Interpretation, and Reporting of Whole-Body MRI in Myeloma: Myeloma Response Assessment and Diagnosis System (MY-RADS). Radiology, Vol.291 (1), pp. 5-13.  show abstract

Ahmed, N., Sriskandarajah, P., Burd, C., Riddell, A., Boyd, K., Kaiser, M. & Messiou, C. (2019). Detection of avascular necrosis on routine diffusion-weighted whole body MRI in patients with multiple myeloma. The british journal of radiology, Vol.92 (1097), pp. 20180822-20180822.

Went, M., Sud, A., Li, N., Johnson, D.C., Mitchell, J.S., Kaiser, M. & Houlston, R.S. (2019). Regions of homozygosity as risk factors for multiple myeloma. Annals of human genetics, Vol.83 (4), pp. 231-238.

Jones, J.R., Weinhold, N., Ashby, C., Walker, B.A., Wardell, C., Pawlyn, C., Rasche, L., Melchor, L., Cairns, D.A., Gregory, W.M., et al. (2019). Clonal evolution in myeloma: the impact of maintenance lenalidomide and depth of response on the genetics and sub-clonal structure of relapsed disease in uniformly treated newly diagnosed patients. Haematologica, Vol.104 (7), pp. 1440-1450.

Hoang, P.H., Cornish, A.J., Dobbins, S.E., Kaiser, M. & Houlston, R.S. (2019). Mutational processes contributing to the development of multiple myeloma. Blood cancer journal, Vol.9 (8).

Jackson, G.H., Davies, F.E., Pawlyn, C., Cairns, D.A., Striha, A., Collett, C., Waterhouse, A., Jones, J.R., Kishore, B., Garg, M., et al. (2019). Response-adapted intensification with cyclophosphamide, bortezomib, and dexamethasone versus no intensification in patients with newly diagnosed multiple myeloma (Myeloma XI): a multicentre, open-label, randomised, phase 3 trial. The lancet haematology, .

Went, M., Kinnersley, B., Sud, A., Johnson, D.C., Weinhold, N., Försti, A., van Duin, M., Orlando, G., Mitchell, J.S., Kuiper, R., et al. (2019). Transcriptome-wide association study of multiple myeloma identifies candidate susceptibility genes. Human genomics, Vol.13 (1).

Shah, V., Sherborne, A.L., Walker, B.A., Johnson, D.C., Boyle, E.M., Ellis, S., Begum, D.B., Proszek, P.Z., Jones, J.R., Pawlyn, C., et al. (2018). Prediction of outcome in newly diagnosed myeloma: a meta-analysis of the molecular profiles of 1905 trial patients. Leukemia, Vol.32 (1), pp. 102-110.

Winfield, J.M., Poillucci, G., Blackledge, M.D., Collins, D.J., Shah, V., Tunariu, N., Kaiser, M.F. & Messiou, C. (2018). Apparent diffusion coefficient of vertebral haemangiomas allows differentiation from malignant focal deposits in whole-body diffusion-weighted MRI. European radiology, Vol.28 (4), pp. 1687-1691.

Shah, V., Johnson, D.C., Sherborne, A.L., Ellis, S., Aldridge, F.M., Howard-Reeves, J., Begum, F., Price, A., Kendall, J., Chiecchio, L., et al. (2018). Subclonal TP53 copy number is associated with prognosis in multiple myeloma. Blood, Vol.132 (23), pp. 2465-2469.  show abstract

Messiou, C. & Kaiser, M. (2018). Whole-Body Imaging in Multiple Myeloma. Magnetic resonance imaging clinics of north america, Vol.26 (4), pp. 509-525.

Boyle, E.M., Ashby, C., Wardell, C.P., Rowczenio, D., Sachchithanantham, S., Wang, Y., Johnson, S.K., Bauer, M.A., Weinhold, N., Kaiser, M.F., et al. (2018). The genomic landscape of plasma cells in systemic light chain amyloidosis. Blood, Vol.132 (26), pp. 2775-2777.

Sriskandarajah, P., Pawlyn, C., Mohammed, K., Dearden, C.E., Davies, F.E., Morgan, G.J., Boyd, K.D. & Kaiser, M.F. (2017). The efficacy and tolerability of pomalidomide in relapsed/refractory myeloma patients in a "real-world" study: the Royal Marsden Hospital experience. Leuk lymphoma, Vol.58 (2), pp. 494-497.

Pawlyn, C., Bright, M.D., Buros, A.F., Stein, C.K., Walters, Z., Aronson, L.I., Mirabella, F., Jones, J.R., Kaiser, M.F., Walker, B.A., et al. (2017). Overexpression of EZH2 in multiple myeloma is associated with poor prognosis and dysregulation of cell cycle control. Blood cancer journal, Vol.7 (3), pp. e549-e549.

Johnson, D.C., Lenive, O., Mitchell, J., Jackson, G., Owen, R., Drayson, M., Cook, G., Jones, J.R., Pawlyn, C., Davies, F.E., et al. (2017). Neutral tumor evolution in myeloma is associated with poor prognosis. Blood, Vol.130 (14), pp. 1639-1643.  show abstract

Moreau, P., Dimopoulos, M.A., Richardson, P.G., Siegel, D.S., Cavo, M., Corradini, P., Weisel, K., Delforge, M., O'Gorman, P., Song, K., et al. (2017). Adverse event management in patients with relapsed and refractory multiple myeloma taking pomalidomide plus low-dose dexamethasone: A pooled analysis. European journal of haematology, Vol.99 (3), pp. 199-206.

Campbell, J.P., Heaney, J.L., Pandya, S., Afzal, Z., Kaiser, M., Owen, R., Child, J.A., Gregory, W., Morgan, G.J., Jackson, G.H., et al. (2017). Active multiple myeloma suppresses and typically eliminates coexisting MGUS. British journal of cancer, Vol.117 (6), pp. 835-839.

Li, N., Johnson, D.C., Weinhold, N., Kimber, S., Dobbins, S.E., Mitchell, J.S., Kinnersley, B., Sud, A., Law, P.J., Orlando, G., et al. (2017). Genetic Predisposition to Multiple Myeloma at 5q15 Is Mediated by an ELL2 Enhancer Polymorphism. Cell reports, Vol.20 (11), pp. 2556-2564.

Shah, V., Boyd, K.D., Houlston, R.S. & Kaiser, M.F. (2017). Constitutional mutation in CDKN2A is associated with long term survivorship in multiple myeloma: a case report. Bmc cancer, Vol.17 (1).

Went, M., Sud, A., Law, P.J., Johnson, D.C., Weinhold, N., Försti, A., van Duin, M., Mitchell, J.S., Chen, B., Kuiper, R., et al. (2017). Assessing the effect of obesity-related traits on multiple myeloma using a Mendelian randomisation approach. Blood cancer j, Vol.7 (6), pp. e573-e573.

Wale, A., Pawlyn, C., Kaiser, M. & Messiou, C. (2016). Frequency, distribution and clinical management of incidental findings and extramedullary plasmacytomas in whole body diffusion weighted magnetic resonance imaging in patients with multiple myeloma. Haematologica, Vol.101 (4), pp. e142-e144.

Pawlyn, C., Fowkes, L., Otero, S., Jones, J.R., Boyd, K.D., Davies, F.E., Morgan, G.J., Collins, D.J., Sharma, B., Riddell, A., et al. (2016). Whole-body diffusion-weighted MRI: a new gold standard for assessing disease burden in patients with multiple myeloma?. Leukemia, Vol.30 (6), pp. 1446-1448.

Mitchell, J.S., Li, N., Weinhold, N., Försti, A., Ali, M., van Duin, M., Thorleifsson, G., Johnson, D.C., Chen, B., Halvarsson, B.-., et al. (2016). Genome-wide association study identifies multiple susceptibility loci for multiple myeloma. Nature communications, Vol.7 (1).

Brown, S., Hinsley, S., Ballesteros, M., Bourne, S., McGarry, P., Sherratt, D., Flanagan, L., Gregory, W., Cavenagh, J., Owen, R., et al. (2016). The MUK five protocol: a phase II randomised, controlled, parallel group, multi-centre trial of carfilzomib, cyclophosphamide and dexamethasone (CCD) vs cyclophosphamide, bortezomib (Velcade) and dexamethasone (CVD) for first relapse and primary refractory multiple myeloma. Bmc hematology, Vol.16 (1).

Jones, J.R., Cairns, D.A., Gregory, W.M., Collett, C., Pawlyn, C., Sigsworth, R., Striha, A., Henderson, R., Kaiser, M.F., Jenner, M., et al. (2016). Second malignancies in the context of lenalidomide treatment: an analysis of 2732 myeloma patients enrolled to the Myeloma XI trial. Blood cancer journal, Vol.6 (12), pp. e506-e506.

Dimopoulos, M.A., Palumbo, A., Corradini, P., Cavo, M., Delforge, M., Di Raimondo, F., Weisel, K.C., Oriol, A., Hansson, M., Vacca, A., et al. (2016). Safety and efficacy of pomalidomide plus low-dose dexamethasone in STRATUS (MM-010): a phase 3b study in refractory multiple myeloma. Blood, Vol.128 (4), pp. 497-503.  show abstract

Johnson, D.C., Weinhold, N., Mitchell, J.S., Chen, B., Kaiser, M., Hillengass, J., Bertsch, U., Gregory, W.A., Cairns, D., Jackson, G.H., et al. (2016). Genome-wide association study identifies variation at 6q25 1 associated with survival in multiple myeloma. Nature communications, Vol.7.

Johnson, D.C., Weinhold, N., Mitchell, J., Chen, B., Stephens, O.W., Försti, A., Nickel, J., Kaiser, M., Gregory, W.A., Cairns, D., et al. (2016). Genetic factors influencing the risk of multiple myeloma bone disease. Leukemia, Vol.30, pp. 883-888.

Li, N., Johnson, D.C., Weinhold, N., Studd, J.B., Orlando, G., Mirabella, F., Mitchell, J.S., Meissner, T., Kaiser, M., Goldschmidt, H., et al. (2016). Multiple myeloma risk variant at 7p15 3 creates an IRF4-binding site and interferes with CDCA7L expression. Nature communications, Vol.7.

Pawlyn, C., Kaiser, M.F., Heuck, C., Melchor, L., Wardell, C.P., Murison, A., Chavan, S.S., Johnson, D.C., Dahir, N.M., Proszek, P.Z., et al. (2016). The spectrum and clinical impact of epigenetic modifier mutations in myeloma. Clinical cancer research, Vol.22, pp. 5783-5794.

Boyle, E.M., Proszek, P.Z., Kaiser, M.F., Begum, D., Dahir, N., Savola, S., Wardell, C.P., Leleu, X., Ross, F.M., Chiecchio, L., et al. (2015). A Molecular Diagnostic Approach Able to Detect the Recurrent Genetic Prognostic Factors Typical of Presenting Myeloma. Genes chromosomes & cancer, Vol.54 (2), pp. 91-98.

Kühnl, A., Valk, P.J., Sanders, M.A., Ivey, A., Hills, R.K., Mills, K.I., Gale, R.E., Kaiser, M.F., Dillon, R., Joannides, M., et al. (2015). Downregulation of the Wnt inhibitor CXXC5 predicts a better prognosis in acute myeloid leukemia. Blood, Vol.125 (19), pp. 2985-2994.  show abstract

Messiou, C. & Kaiser, M. (2015). Whole body diffusion weighted MRI - a new view of myeloma. British journal of haematology, Vol.171 (1), pp. 29-37.

Pawlyn, C., Melchor, L., Murison, A., Wardell, C.P., Brioli, A., Boyle, E.M., Kaiser, M.F., Walker, B.A., Begum, D.B., Dahir, N.B., et al. (2015). Coexistent hyperdiploidy does not abrogate poor prognosis in myeloma with adverse cytogenetics and may precede IGH translocations. Blood, Vol.125 (5), pp. 831-840.  show abstract

Walker, B.A., Wardell, C.P., Murison, A., Boyle, E.M., Dahir, N.M., Proszek, P.Z., Melchor, L., Pawlyn, C., Kaiser, M.F., Johnson, D.C., et al. (2015). APOBEC family mutational signatures are associated with poor prognosis translocations in multiple myeloma. Nature communications, Vol.6.

Wu, P., Walker, B.A., Broyl, A., Kaiser, M., Johnson, D.C., Kuiper, R., van Duin, M., Gregory, W.M., Davies, F.E., Brewer, D., et al. (2015). A gene expression based predictor for high risk myeloma treated with intensive therapy and autologous stem cell rescue. Leukemia & lymphoma, Vol.56, pp. 594-601.

Mitchell, J.S., Johnson, D.C., Litchfield, K., Broderick, P., Weinhold, N., Davies, F.E., Gregory, W.A., Jackson, G.H., Kaiser, M., Morgan, G.J., et al. (2015). Implementation of genome-wide complex trait analysis to quantify the heritability in multiple myeloma. Scientific reports, Vol.5.

Walker, B.A., Boyle, E.M., Wardell, C.P., Murison, A., Begum, D.B., Dahir, N.M., Proszek, P.Z., Johnson, D.C., Kaiser, M.F., Melchor, L., et al. (2015). Mutational spectrum, copy number changes, and outcome: results of a sequencing study of patients with newly diagnosed myeloma. Journal of clinical oncology, Vol.33, pp. 3911-3920.

Walker, B.A., Wardell, C.P., Melchor, L., Brioli, A., Johnson, D.C., Kaiser, M.F., Mirabella, F., Lopez-Corral, L., Humphray, S., Murray, L., et al. (2014). Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms. Leukemia, Vol.28 (2), pp. 384-390.  show abstract

Pawlyn, C., Kaiser, M.F., Davies, F.E. & Morgan, G.J. (2014). Current and potential epigenetic targets in multiple myeloma. Epigenomics, Vol.6 (2), pp. 215-228.  show abstract

Pawlyn, C., Hookway, E., Cain, P., Pliuskys, L., Kaiser, M.F., Bright, M., Aronson, L.I., Murison, A., Lindow, M., Obad, S., et al. (2014). Histone Demethylase Inhibition As a Novel Therapeutic Strategy in Myeloma. Blood, Vol.124 (21).

Melchor, L., Brioli, A., Wardell, C.P., Murison, A., Potter, N.E., Kaiser, M.F., Fryer, R.A., Johnson, D.C., Begum, D.B., Hulkki Wilson, S., et al. (2014). Single-cell genetic analysis reveals the composition of initiating clones and phylogenetic patterns of branching and parallel evolution in myeloma. Leukemia, Vol.28 (8), pp. 1705-1715.  show abstract

Pawlyn, C., Khan, M.S., Muls, A., Sriskandarajah, P., Kaiser, M.F., Davies, F.E., Morgan, G.J. & Andreyev, H.J. (2014). Lenalidomide-induced diarrhea in patients with myeloma is caused by bile acid malabsorption that responds to treatment. Blood, Vol.124 (15), pp. 2467-2468.

Brioli, A., Giles, H., Pawlyn, C., Campbell, J.P., Kaiser, M.F., Melchor, L., Jackson, G.H., Gregory, W.M., Owen, R.G., Child, J.A., et al. (2014). Serum free immunoglobulin light chain evaluation as a marker of impact from intraclonal heterogeneity on myeloma outcome. Blood, Vol.123 (22), pp. 3414-3419.  show abstract

Mirabella, F., Murison, A., Aronson, L.I., Wardell, C.P., Thompson, A.J., Hanrahan, S.J., Fok, J.H., Pawlyn, C., Kaiser, M.F., Walker, B.A., et al. (2014). A novel functional role for MMSET in RNA processing based on the link between the REIIBP isoform and its interaction with the SMN complex. Plos one, Vol.9 (6), p. e99493.  show abstract

Mirabella, F., Wu, P., Wardell, C.P., Kaiser, M.F., Walker, B.A., Johnson, D.C. & Morgan, G.J. (2013). MMSET is the key molecular target in t(4;14) myeloma. Blood cancer j, Vol.3, p. e114.

Kaiser, M.F., Heider, U., Mieth, M., Zang, C., von Metzler, I. & Sezer, O. (2013). The proteasome inhibitor bortezomib stimulates osteoblastic differentiation of human osteoblast precursors via upregulation of vitamin D receptor signalling. Eur j haematol, Vol.90 (4), pp. 263-272.  show abstract

Kaiser, M.F., Heider, U., Mieth, M., Zang, C., von Metzler, I. & Sezer, O. (2013). The proteasome inhibitor bortezomib stimulates osteoblastic differentiation of human osteoblast precursors via upregulation of vitamin D receptor signalling. European journal of haematology, Vol.90 (4), pp. 263-272.

Brioli, A., Boyd, K.D., Kaiser, M.F., Pawlyn, C., Wu, P., Gregory, W.M., Owen, R., Ross, F.M., Jackson, G.H., Cavo, M., et al. (2013). Response and biological subtype of myeloma are independent prognostic factors and combine to define outcome after high-dose therapy. Br j haematol, Vol.161 (2), pp. 291-294.

Kaiser, M.F., Walker, B.A., Hockley, S.L., Begum, D.B., Wardell, C.P., Gonzalez, D., Ross, F.M., Davies, F.E. & Morgan, G.J. (2013). A TC classification-based predictor for multiple myeloma using multiplexed real-time quantitative PCR. Leukemia, Vol.27 (8), pp. 1754-1757.

Wu, P., Agnelli, L., Walker, B.A., Todoerti, K., Lionetti, M., Johnson, D.C., Kaiser, M., Mirabella, F., Wardell, C., Gregory, W.M., et al. (2013). Improved risk stratification in myeloma using a microRNA-based classifier. British journal of haematology, Vol.162 (3), pp. 348-359.

Brioli, A., Kaiser, M.F., Pawlyn, C., Wu, P., Gregory, W.M., Owen, R., Ross, F.M., Jackson, G.H., Cavo, M., Davies, F.E., et al. (2013). Biologically defined risk groups can be used to define the impact of thalidomide maintenance therapy in newly diagnosed multiple myeloma. Leuk lymphoma, Vol.54 (9), pp. 1975-1981.  show abstract

Kaiser, M.F., Johnson, D.C., Wu, P., Walker, B.A., Brioli, A., Mirabella, F., Wardell, C.P., Melchor, L., Davies, F.E. & Morgan, G.J., et al. (2013). Global methylation analysis identifies prognostically important epigenetically inactivated tumor suppressor genes in multiple myeloma. Blood, Vol.122 (2), pp. 219-226.  show abstract

Walker, B.A., Wardell, C.P., Johnson, D.C., Kaiser, M.F., Begum, D.B., Dahir, N.B., Ross, F.M., Davies, F.E., Gonzalez, D. & Morgan, G.J., et al. (2013). Characterization of IGH locus breakpoints in multiple myeloma indicates a subset of translocations appear to occur in pregerminal center B cells. Blood, Vol.121 (17), pp. 3413-3419.  show abstract

Lamottke, B., Kaiser, M., Mieth, M., Heider, U., Gao, Z., Nikolova, Z., Jensen, M.R., Sterz, J., von Metzler, I. & Sezer, O., et al. (2012). The novel, orally bioavailable HSP90 inhibitor NVP-HSP990 induces cell cycle arrest and apoptosis in multiple myeloma cells and acts synergistically with melphalan by increased cleavage of caspases. Eur j haematol, Vol.88 (5), pp. 406-415.  show abstract

Morgan, G.J. & Kaiser, M.F. (2012). How to use new biology to guide therapy in multiple myeloma. Hematology am soc hematol educ program, Vol.2012, pp. 342-349.  show abstract

Huetter, G., Kaiser, M., Neumann, M., Mossner, M., Nowak, D., Baldus, C.D., Goekbuget, N., Hoelzer, D., Thiel, E. & Hofmann, W.-., et al. (2011). Epigenetic regulation of PAX5 expression in acute T-cell lymphoblastic leukemia. Leukemia research, Vol.35 (5), pp. 614-619.

Kaiser, M., Kuehnl, A., Reins, J., Fischer, S., Ortiz-Tanchez, J., Schlee, C., Mochmann, L.H., Heesch, S., Benlasfer, O., Hofmann, W.-., et al. (2011). Antileukemic activity of the HSP70 inhibitor pifithrin-mu in acute leukemia. Blood cancer journal, Vol.1.

Kühnl, A., Gökbuget, N., Kaiser, M., Schlee, C., Stroux, A., Burmeister, T., Mochmann, L.H., Hoelzer, D., Hofmann, W.-., Thiel, E., et al. (2011). Overexpression of LEF1 predicts unfavorable outcome in adult patients with B-precursor acute lymphoblastic leukemia. Blood, Vol.118 (24), pp. 6362-6367.  show abstract

Kühnl, A., Kaiser, M., Neumann, M., Fransecky, L., Heesch, S., Radmacher, M., Marcucci, G., Bloomfield, C.D., Hofmann, W.-., Thiel, E., et al. (2011). High expression of IGFBP2 is associated with chemoresistance in adult acute myeloid leukemia. Leuk res, Vol.35 (12), pp. 1585-1590.  show abstract

Heider, U., Rademacher, J., Kaiser, M., Kleeberg, L., von Metzler, I. & Sezer, O. (2010). Decrease in CD4+ T-cell counts in patients with multiple myeloma treated with bortezomib. Clin lymphoma myeloma leuk, Vol.10 (2), pp. 134-137.  show abstract

Kaiser, M., Lamottke, B., Mieth, M., Jensen, M.R., Quadt, C., Garcia-Echeverria, C., Atadja, P., Heider, U., von Metzler, I., Türkmen, S., et al. (2010). Synergistic action of the novel HSP90 inhibitor NVP-AUY922 with histone deacetylase inhibitors, melphalan, or doxorubicin in multiple myeloma. Eur j haematol, Vol.84 (4), pp. 337-344.  show abstract

Sterz, J., Jakob, C., Kuckelkorn, U., Heider, U., Mieth, M., Kleeberg, L., Kaiser, M., Kloetzel, P.-., Sezer, O. & von Metzler, I., et al. (2010). BSc2118 is a novel proteasome inhibitor with activity against multiple myeloma. Eur j haematol, Vol.85 (2), pp. 99-107.  show abstract

Heider, U., Kaiser, M., Mieth, M., Lamottke, B., Rademacher, J., Jakob, C., Braendle, E., Stover, D. & Sezer, O. (2009). Serum concentrations of DKK-1 decrease in patients with multiple myeloma responding to anti-myeloma treatment. Eur j haematol, Vol.82 (1), pp. 31-38.  show abstract

von Metzler, I., Krebbel, H., Kuckelkorn, U., Heider, U., Jakob, C., Kaiser, M., Fleissner, C., Terpos, E. & Sezer, O. (2009). Curcumin diminishes human osteoclastogenesis by inhibition of the signalosome-associated I kappaB kinase. J cancer res clin oncol, Vol.135 (2), pp. 173-179.  show abstract

von Metzler, I., Heider, U., Mieth, M., Lamottke, B., Kaiser, M., Jakob, C. & Sezer, O. (2009). Synergistic interaction of proteasome and topoisomerase II inhibition in multiple myeloma. Exp cell res, Vol.315 (14), pp. 2471-2478.  show abstract

Kleeberg, L., Morgera, S., Jakob, C., Hocher, B., Schneider, M., Peters, H., Rötzer, S., Müller, C., Kaiser, M., Fleissner, C., et al. (2009). Novel renal replacement strategies for the elimination of serum free light chains in patients with kappa light chain nephropathy. Eur j med res, Vol.14, pp. 47-54.  show abstract

Heider, U., von Metzler, I., Kaiser, M., Rosche, M., Sterz, J., Rötzer, S., Rademacher, J., Jakob, C., Fleissner, C., Kuckelkorn, U., et al. (2008). Synergistic interaction of the histone deacetylase inhibitor SAHA with the proteasome inhibitor bortezomib in mantle cell lymphoma. Eur j haematol, Vol.80 (2), pp. 133-142.  show abstract

Kaiser, M., Mieth, M., Liebisch, P., Oberländer, R., Rademacher, J., Jakob, C., Kleeberg, L., Fleissner, C., Braendle, E., Peters, M., et al. (2008). Serum concentrations of DKK-1 correlate with the extent of bone disease in patients with multiple myeloma. Eur j haematol, Vol.80 (6), pp. 490-494.  show abstract

Jakob, C., Sterz, J., Liebisch, P., Mieth, M., Rademacher, J., Goerke, A., Heider, U., Fleissner, C., Kaiser, M., von Metzler, I., et al. (2008). Incorporation of the bone marker carboxy-terminal telopeptide of type-1 collagen improves prognostic information of the International Staging System in newly diagnosed symptomatic multiple myeloma. Leukemia, Vol.22 (9), pp. 1767-1772.  show abstract

Hecht, M., von Metzler, I., Sack, K., Kaiser, M. & Sezer, O. (2008). Interactions of myeloma cells with osteoclasts promote tumour expansion and bone degradation through activation of a complex signalling network and upregulation of cathepsin K, matrix metalloproteinases (MMPs) and urokinase plasminogen activator (uPA). Exp cell res, Vol.314 (5), pp. 1082-1093.  show abstract

Schwarzer, R., Kaiser, M., Acikgoez, O., Heider, U., Mathas, S., Preissner, R., Sezer, O., Doerken, B. & Jundt, F. (2008). Notch inhibition blocks multiple myeloma cell-induced osteoclast activation. Leukemia, Vol.22 (12), pp. 2273-2277.

Jakob, C., Egerer, K., Liebisch, P., Türkmen, S., Zavrski, I., Kuckelkorn, U., Heider, U., Kaiser, M., Fleissner, C., Sterz, J., et al. (2007). Circulating proteasome levels are an independent prognostic factor for survival in multiple myeloma. Blood, Vol.109 (5), pp. 2100-2105.  show abstract

Hecht, M., Heider, U., Kaiser, M., von Metzler, I., Sterz, J. & Sezer, O. (2007). Osteoblasts promote migration and invasion of myeloma cells through upregulation of matrix metalloproteinases, urokinase plasminogen activator, hepatocyte growth factor and activation of p38 MAPK. Br j haematol, Vol.138 (4), pp. 446-458.  show abstract

von Metzler, I., Krebbel, H., Hecht, M., Manz, R.A., Fleissner, C., Mieth, M., Kaiser, M., Jakob, C., Sterz, J., Kleeberg, L., et al. (2007). Bortezomib inhibits human osteoclastogenesis. Leukemia, Vol.21 (9), pp. 2025-2034.  show abstract

Zavrski, I., Jakob, C., Kaiser, M., Fleissner, C., Heider, U. & Sezer, O. (2007). Molecular and clinical aspects of proteasome inhibition in the treatment of cancer. Recent results cancer res, Vol.176, pp. 165-176.  show abstract

Zavrski, I., Kleeberg, L., Kaiser, M., Fleissner, C., Heider, U., Sterz, J., Jakob, C. & Sezer, O. (2007). Proteasome as an emerging therapeutic target in cancer. Curr pharm des, Vol.13 (5), pp. 471-485.  show abstract

Heider, U., Kaiser, M., Sterz, J., Zavrski, I., Jakob, C., Fleissner, C., Eucker, J., Possinger, K. & Sezer, O. (2006). Histone deacetylase inhibitors reduce VEGF production and induce growth suppression and apoptosis in human mantle cell lymphoma. Eur j haematol, Vol.76 (1), pp. 42-50.  show abstract

Kaiser, M., Zavrski, I., Sterz, J., Jakob, C., Fleissner, C., Kloetzel, P.-., Sezer, O. & Heider, U. (2006). The effects of the histone deacetylase inhibitor valproic acid on cell cycle, growth suppression and apoptosis in multiple myeloma. Haematologica, Vol.91 (2), pp. 248-251.  show abstract

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