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Journal Articles

Lipinski, K.A., Barber, L.J., Davies, M.N., Ashenden, M., Sottoriva, A. & Gerlinger, M. (2016). Cancer Evolution and the Limits of Predictability in Precision Cancer Medicine. Trends cancer, Vol.2 (1), pp. 49-63.  show abstract

Gerlinger, M., Horswell, S., Larkin, J., Rowan, A.J., Salm, M.P., Varela, I., Fisher, R., McGranahan, N., Matthews, N., Santos, C.R., et al. (2014). Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing. Nat genet, Vol.46 (3), pp. 225-233.  show abstract

de Bruin, E.C., McGranahan, N., Mitter, R., Salm, M., Wedge, D.C., Yates, L., Jamal-Hanjani, M., Shafi, S., Murugaesu, N., Rowan, A.J., et al. (2014). Spatial and temporal diversity in genomic instability processes defines lung cancer evolution. Science, Vol.346 (6206), pp. 251-256.  show abstract

Barber, L.J., Davies, M.N. & Gerlinger, M. (2014). Dissecting cancer evolution at the macro-heterogeneity and micro-heterogeneity scale. Current opinion in genetics and development, Vol.30 (Cancer Genomics), pp. 1-6.  show abstract

Gerlinger, M., Rowan, A.J., Horswell, S., Larkin, J., Endesfelder, D., Gronroos, E., Martinez, P., Matthews, N., Stewart, A., Tarpey, P., et al. (2012). Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing. New england journal of medicine, Vol.366 (10), pp. 883-892.

Barber, L., Mansukhani, S., Kleftogiannis, D., Moorcraft, S.Y., Davidson, M., Woolston, A., Proszek, P., Griffiths, B., Fenwick, K., Matthews, N., et al. Ultra-sensitive mutation detection and genome-wide DNA copy number reconstruction by error corrected circulating tumor DNA sequencing. Clinical chemistry, .

Gonzalez-Exposito, R., Semiannikova, M., Griffiths, B., Khan, K., Barber, L., Woolston, A., Spain, G., von Loga, K., Challoner, B., Patel, R., et al. CEA Expression Heterogeneity and Plasticity Confer Resistance to the CEA-Targeting Bispecific Immunotherapy Antibody Cibisatamab (CEA-TCB) in Patient-Derived Colorectal Cancer Organoids. Journal for immunotherapy of cancer, .  show abstract

Davidson, M., Barber, L.J., Woolston, A., Cafferkey, C., Mansukhani, S., Griffiths, B., Moorcraft, S.-., Rana, I., Begum, R., Assiotis, I., et al. Detecting and Tracking Circulating Tumour DNA Copy Number Profiles during First Line Chemotherapy in Oesophagogastric Adenocarcinoma. Cancers, Vol.11 (5), pp. 736-736.  show abstract

Woolston, A., Khan, K., Spain, G., Barber, L., Griffiths, B., Gonzalez-Exposito, R., Hornsteiner, L., Punta, M., Patil, Y., Newey, A., et al. Genomic and transcriptomic determinants of therapy resistance and immune landscape evolution during anti-EGFR treatment in colorectal cancer. Cancer cell, .