Main Menu

Publications Highlights View all by category

Types of Publications

Journal Articles

Jones, M. Beuron, F. Borg, A. Nans, A. Earl, C.P. Briggs, D.C. Snijders, A.P. Bowles, M. Morris, E.P. Linch, M. McDonald, N.Q. (2020). Cryo-EM structures of the XPF-ERCC1 endonuclease reveal how DNA-junction engagement disrupts an auto-inhibited conformation. Nature communications, Vol.11 (1).

Faull, S.V. Lau, A.M. Martens, C. Ahdash, Z. Hansen, K. Yebenes, H. Schmidt, C. Beuron, F. Cronin, N.B. Morris, E.P. Politis, A. (2019). Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome. Nature communications, Vol.10 (1).

Burgoyne, T. Heumann, J.M. Morris, E.P. Knupp, C. Liu, J. Reedy, M.K. Taylor, K.A. Wang, K. Luther, P.K. (2019). Three-dimensional structure of the basketweave Z-band in midshipman fish sonic muscle. Proceedings of the national academy of sciences, Vol.116 (31), pp. 15534-15539.  show abstract

Morris, E.P. da Fonseca, P.C. (2017). High-resolution cryo-EM proteasome structures in drug development. Acta crystallographica section d structural biology, Vol.73 (6), pp. 522-533.  show abstract

Paul, D.M. Squire, J.M. Morris, E.P. (2017). Relaxed and active thin filament structures; a new structural basis for the regulatory mechanism. Journal of structural biology, Vol.197 (3), pp. 365-371.

Squire, J.M. Paul, D.M. Morris, E.P. (2017). Myosin and Actin Filaments in Muscle: Structures and Interactions. , , pp. 319-371.

Bachmann, G. Richards, M.W. Winter, A. Beuron, F. Morris, E. Bayliss, R. (2016). A closed conformation of the Caenorhabditis elegans separase–securin complex. Open biology, Vol.6 (4), pp. 160032-160032.

Mariotti, L. Templeton, C.M. Ranes, M. Paracuellos, P. Cronin, N. Beuron, F. Morris, E. Guettler, S. (2016). Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-β-Catenin Signaling. Molecular cell, Vol.63 (3), pp. 498-513.  show abstract

Taylor, A.I. Beuron, F. Peak-Chew, S.-. Morris, E.P. Herdewijn, P. Holliger, P. (2016). Nanostructures from Synthetic Genetic Polymers. Chembiochem, Vol.17 (12), pp. 1107-1110.

Burgoyne, T. Morris, E.P. Luther, P.K. (2015). Three-Dimensional Structure of Vertebrate Muscle Z-Band: The Small-Square Lattice Z-Band in Rat Cardiac Muscle. Journal of molecular biology, Vol.427 (22), pp. 3527-3537.

da Fonseca, P.C. Morris, E.P. (2015). Cryo-EM reveals the conformation of a substrate analogue in the human 20S proteasome core. Nature communications, Vol.6 (1).

Coster, G. Frigola, J. Beuron, F. Morris, E.P. Diffley, J.F. (2014). Origin licensing requires ATP binding and hydrolysis by the MCM replicative helicase. Mol cell, Vol.55 (5), pp. 666-677.  show abstract

On, K.F. Beuron, F. Frith, D. Snijders, A.P. Morris, E.P. Diffley, J.F. (2014). Prereplicative complexes assembled in vitro support origin-dependent and independent DNA replication. Embo j, Vol.33 (6), pp. 605-620.  show abstract

Goodman, K.M. Kjær, S. Beuron, F. Knowles, P.P. Nawrotek, A. Burns, E.M. Purkiss, A.G. George, R. Santoro, M. Morris, E.P. McDonald, N.Q. (2014). RET recognition of GDNF-GFRα1 ligand by a composite binding site promotes membrane-proximal self-association. Cell rep, Vol.8 (6), pp. 1894-1904.  show abstract

Al-Khayat, H.A. Kensler, R.W. Squire, J.M. Marston, S.B. Morris, E.P. (2013). Atomic model of the human cardiac muscle myosin filament. Proc natl acad sci u s a, Vol.110 (1), pp. 318-323.  show abstract

Zhang, Z. Yang, J. Kong, E.H. Chao, W.C. Morris, E.P. da Fonseca, P.C. Barford, D. (2013). Recombinant expression, reconstitution and structure of human anaphase-promoting complex (APC/C). Biochem j, Vol.449 (2), pp. 365-371.  show abstract

Lamber, E.P. Beuron, F. Morris, E.P. Svergun, D.I. Mittnacht, S. (2013). Structural insights into the mechanism of phosphoregulation of the retinoblastoma protein. Plos one, Vol.8 (3), p. e58463.  show abstract

Pinotsis, N. Chatziefthimiou, S.D. Berkemeier, F. Beuron, F. Mavridis, I.M. Konarev, P.V. Svergun, D.I. Morris, E. Rief, M. Wilmanns, M. (2012). Superhelical Architecture of the Myosin Filament-Linking Protein Myomesin with Unusual Elastic Properties. Plos biology, Vol.10 (2).

Spagnolo, L. Barbeau, J. Curtin, N.J. Morris, E.P. Pearl, L.H. (2012). Visualization of a DNA-PK/PARP1 complex. Nucleic acids res, Vol.40 (9), pp. 4168-4177.  show abstract

He, J. Kulkarni, K. da Fonseca, P.C. Krutauz, D. Glickman, M.H. Barford, D. Morris, E.P. (2012). The structure of the 26S proteasome subunit Rpn2 reveals its PC repeat domain as a closed toroid of two concentric α-helical rings. Structure, Vol.20 (3), pp. 513-521.  show abstract

da Fonseca, P.C. He, J. Morris, E.P. (2012). Molecular model of the human 26S proteasome. Mol cell, Vol.46 (1), pp. 54-66.  show abstract

Bhanumathy, C. da Fonseca, P.C. Morris, E.P. Joseph, S.K. (2012). Identification of functionally critical residues in the channel domain of inositol trisphosphate receptors. J biol chem, Vol.287 (52), pp. 43674-43684.  show abstract

Enchev, R.I. Scott, D.C. da Fonseca, P.C. Schreiber, A. Monda, J.K. Schulman, B.A. Peter, M. Morris, E.P. (2012). Structural basis for a reciprocal regulation between SCF and CSN. Cell rep, Vol.2 (3), pp. 616-627.  show abstract

Al-Khayat, H.A. Kensler, R.W. Squire, J.M. Marston, S.B. Morris, E.P. (2012). 3-Dimensional Structure of Human Cardiac Muscle Myosin Filaments by Electron Microscopy and Single Particle Analysis. Biophysical journal, Vol.102 (3), pp. 149A-150A.

Morris, E.P. Rivera-Calzada, A. da Fonseca, P.C. Llorca, O. Pearl, L.H. Spagnolo, L. (2011). Evidence for a remodelling of DNA-PK upon autophosphorylation from electron microscopy studies. Nucleic acids res, Vol.39 (13), pp. 5757-5767.  show abstract

da Fonseca, P.C. Kong, E.H. Zhang, Z. Schreiber, A. Williams, M.A. Morris, E.P. Barford, D. (2011). Structures of APC/C(Cdh1) with substrates identify Cdh1 and Apc10 as the D-box co-receptor. Nature, Vol.470 (7333), pp. 274-278.  show abstract

Schreiber, A. Stengel, F. Zhang, Z. Enchev, R.I. Kong, E.H. Morris, E.P. Robinson, C.V. da Fonseca, P.C. Barford, D. (2011). Structural basis for the subunit assembly of the anaphase-promoting complex. Nature, Vol.470 (7333), pp. 227-232.  show abstract

Paul, D.M. Squire, J.M. Morris, E.P. (2010). A novel approach to the structural analysis of partially decorated actin based filaments. J struct biol, Vol.170 (2), pp. 278-285.  show abstract

Anyatonwu, G. Khan, M.T. Schug, Z.T. da Fonseca, P.C. Morris, E.P. Joseph, S.K. (2010). Calcium-dependent Conformational Changes in Inositol Trisphosphate Receptors. J biol chem, Vol.285 (32), pp. 25085-25093.  show abstract

Al-Khayat, H.A. Kensler, R.W. Morris, E.P. Squire, J.M. (2010). Three-Dimensional Structure of the M-region (Bare Zone) of Vertebrate Striated Muscle Myosin Filaments by Single-Particle Analysis. J mol biol, Vol.403 (5), pp. 763-776.  show abstract

Enchev, R.I. Schreiber, A. Beuron, F. Morris, E.P. (2010). Structural insights into the COP9 signalosome and its common architecture with the 26S proteasome lid and eIF3. Structure, Vol.18 (4), pp. 518-527.  show abstract

Wolfram, F. Morris, E. Taylor, C.W. (2010). Three-dimensional structure of recombinant type 1 inositol 1,4,5-trisphosphate receptor. Biochem j, Vol.428 (3), pp. 483-489.  show abstract

Hodgkinson, J.L. Horsley, A. Stabat, D. Simon, M. Johnson, S. da Fonseca, P.C. Morris, E.P. Wall, J.S. Lea, S.M. Blocker, A.J. (2009). Three-dimensional reconstruction of the Shigella T3SS transmembrane regions reveals 12-fold symmetry and novel features throughout. Nat struct mol biol, Vol.16 (5), pp. 477-485.  show abstract

Al-Khayat, H.A. Morris, E.P. Squire, J.M. (2009). The 7-stranded structure of relaxed scallop muscle myosin filaments: Support for a common head configuration in myosin-regulated muscles. J struct biol, Vol.166 (2), pp. 183-194.  show abstract

Remus, D. Beuron, F. Tolun, G. Griffith, J.D. Morris, E.P. Diffley, J.F. (2009). Concerted Loading of Mcm2-7 Double Hexamers around DNA during DNA Replication Origin Licensing. Cell, Vol.139 (4), pp. 719-730.  show abstract

Altschuler, G.M. Dekker, C. McCormack, E.A. Morris, E.P. Klug, D.R. Willison, K.R. (2009). A single amino acid residue is responsible for species-specific incompatibility between CCT and alpha-actin. Febs lett, Vol.583 (4), pp. 782-786.  show abstract

Paul, D.M. Morris, E.P. Kensler, R.W. Squire, J.M. (2009). Structure and orientation of troponin in the thin filament. J biol chem, Vol.284 (22), pp. 15007-15015.  show abstract

Schug, Z.T. da Fonseca, P.C. Bhanumathy, C.D. Wagner, L. Zhang, X.C. Bailey, B. Morris, E.P. Yule, D.I. Joseph, S.K. (2008). Molecular characterization of the inositol 1,4,5-trisphosphate receptor pore-forming segment. J biol chem, Vol.283 (5), pp. 2939-2948.  show abstract

Al-Khayat, H.A. Morris, E.P. Kensler, R.W. Squire, J.M. (2008). Myosin filament 3D structure in mammalian cardiac muscle. J struct biol, Vol.163 (2), pp. 117-126.  show abstract

da Fonseca, P.C. Morris, E.P. (2008). Structure of the human 26S proteasome: subunit radial displacements open the gate into the proteolytic core. J biol chem, Vol.283 (34), pp. 23305-23314.  show abstract

Al-Khayat, H.A. Morris, E.P. Kensler, R.W. Squire, J.M. (2006). 3D structure of relaxed fish muscle myosin filaments by single particle analysis. J struct biol, Vol.155 (2), pp. 202-217.  show abstract

Morosinotto, T. Bassi, R. Frigerio, S. Finazzi, G. Morris, E. Barber, J. (2006). Biochemical and structural analyses of a higher plant photosystem II supercomplex of a photosystem I-less mutant of barley - Consequences of a chronic over-reduction of the plastoquinone pool. Febs j, Vol.273 (20), pp. 4616-4630.  show abstract

Taylor, C.W. da Fonseca, P.C. Morris, E.P. (2004). IP3 receptors: the search for structure. Trends biochem sci, Vol.29 (4), pp. 210-219.  show abstract

Paul, D. Patwardhan, A. Squire, J.M. Morris, E.P. (2004). Single particle analysis of filamentous and highly elongated macromolecular assemblies. J struct biol, Vol.148 (2), pp. 236-250.  show abstract

Patwardhan, A. Paul, D. Al-Khayat, H.A. Morris, E.P. (2004). A measure for the angle between projections based on the extent of correlation between corresponding central sections. J mol biol, Vol.344 (3), pp. 707-724.  show abstract

Al-Khayat, H.A. Morris, E.P. Squire, J.M. (2004). Single particle analysis: a new approach to solving the 3D structure of myosin filaments. J muscle res cell motil, Vol.25 (8), pp. 635-644.  show abstract

da Fonseca, P.C. Morris, S.A. Nerou, E.P. Taylor, C.W. Morris, E.P. (2003). Domain organization of the type 1 inositol 1,4,5-trisphosphate receptor as revealed by single-particle analysis. Proc natl acad sci u s a, Vol.100 (7), pp. 3936-3941.  show abstract

Luther, P.K. Morris, E.P. (2003). Cryoelectron microscopy of refrozen cryosections. J struct biol, Vol.142 (2), pp. 233-240.  show abstract

Barber, J. Morris, E.P. da Fonseca, P.C. (2003). Interaction of the allophycocyanin core complex with photosystem II. Photochem photobiol sci, Vol.2 (5), pp. 536-541.  show abstract

Daniell, S.J. Kocsis, E. Morris, E. Knutton, S. Booy, F.P. Frankel, G. (2003). 3D structure of EspA filaments from enteropathogenic Escherichia coli. Mol microbiol, Vol.49 (2), pp. 301-308.  show abstract

Nield, J. Morris, E.P. Bibby, T.S. Barber, J. (2003). Structural analysis of the photosystem I supercomplex of cyanobacteria induced by iron deficiency. Biochemistry, Vol.42 (11), pp. 3180-3188.  show abstract

Eakins, F. AL-Khayat, H.A. Kensler, R.W. Morris, E.P. Squire, J.M. (2002). 3D Structure of fish muscle myosin filaments. J struct biol, Vol.137 (1-2), pp. 154-163.  show abstract

Squire, J.M. Eakins, F. Kensler, R.W. Morris, E.P. Al-Khayat, H.A. (2002). 3D reconstruction of isolated myosin filaments in fish muscle. Biophys j, Vol.82 (1), pp. 5A-5A.

da Fonseca, P. Morris, E.P. Hankamer, B. Barber, J. (2002). Electron crystallographic study of photosystem II of the cyanobacterium Synechococcus elongatus. Biochemistry, Vol.41 (16), pp. 5163-5167.  show abstract

Hankamer, B. Morris, E. Nield, J. Gerle, C. Barber, J. (2001). Three-dimensional structure of the photosystem II core dimer of higher plants determined by electron microscopy. J struct biol, Vol.135 (3), pp. 262-269.  show abstract

Büchel, C. Morris, E. Orlova, E. Barber, J. (2001). Localisation of the PsbH subunit in photosystem II: a new approach using labelling of His-tags with a Ni(2+)-NTA gold cluster and single particle analysis. J mol biol, Vol.312 (2), pp. 371-379.  show abstract

Morris, E.P. Török, K. (2001). Oligomeric structure of alpha-calmodulin-dependent protein kinase II. J mol biol, Vol.308 (1), pp. 1-8.  show abstract

Nield, J. Orlova, E.V. Morris, E.P. Gowen, B. van Heel, M. Barber, J. (2000). 3D map of the plant photosystem II supercomplex obtained by cryoelectron microscopy and single particle analysis. Nat struct biol, Vol.7 (1), pp. 44-47.  show abstract

Morris, E.P. Hankamer, B.D. Barber, J. (2000). Three-dimensional structure of photosystem II determined by electron crystallography. Biophys j, Vol.78 (1), pp. 8A-8A.

Kruse, O. Hankamer, B. Konczak, C. Gerle, C. Morris, E. Radunz, A. Schmid, G.H. Barber, J. (2000). Phosphatidylglycerol is involved in the dimerization of photosystem II. J biol chem, Vol.275 (9), pp. 6509-6514.  show abstract

Büchel, C. Morris, E. Barber, J. (2000). Crystallisation of CP43, a chlorophyll binding protein of photosystem II: an electron microscopy analysis of molecular packing. J struct biol, Vol.131 (3), pp. 181-186.  show abstract

Barber, J. Morris, E. Büchel, C. (2000). Revealing the structure of the photosystem II chlorophyll binding proteins, CP43 and CP47. Biochim biophys acta, Vol.1459 (2-3), pp. 239-247.  show abstract

Barber, J. Nield, J. Morris, E.P. Hankamer, B. (1999). Subunit positioning in photosystem II revisited. Trends biochem sci, Vol.24 (2), pp. 43-45.

Hankamer, B. Morris, E.P. Barber, J. (1999). Revealing the structure of the oxygen-evolving core dimer of photosystem II by cryoelectron crystallography. Nat struct biol, Vol.6 (6), pp. 560-564.  show abstract

Knupp, C. Luther, P.K. Morris, E.P. Knight, D.P. Squire, J.M. (1999). Partially systematic molecular packing in the hexagonal columnar phase of dogfish egg case collagen. J struct biol, Vol.126 (2), pp. 121-130.  show abstract

Barber, J. Rhee, K.H. Morris, E. Hankamer, B. Nield, J. Boekema, E. Kuhlbrandt, W. (1998). Towards the elucidation of the structure of photosystem II at high resolution. Biophys j, Vol.74 (2), pp. A328-A328.

Squire, J.M. Morris, E.P. (1998). A new look at thin filament regulation in vertebrate skeletal muscle. Faseb j, Vol.12 (10), pp. 761-771.  show abstract

Harford, J. Cantino, M. Chew, M. Denny, R. Hudson, L. Luther, P. Mendelson, R. Morris, E. Squire, J. (1998). Myosin crossbridge configurations in equilibrium states of vertebrate skeletal muscle Heads swing axially or turn upside-down between resting and rigor. Adv exp med biol, Vol.453, pp. 297-308.  show abstract

Rhee, K.H. Morris, E.P. Zheleva, D. Hankamer, B. Kuhlbrandt, W. Barber, J. (1997). Two-dimensional structure of plant photosystem II at 8-angstrom resolution. Nature, Vol.389 (6650), pp. 522-526.  show abstract

Mendelson, R. Morris, E.P. (1997). The structure of the acto-myosin subfragment 1 complex: Results of searches using data from electron microscopy and x-ray crystallography. P natl acad sci usa, Vol.94 (16), pp. 8533-8538.  show abstract

Barber, J. Nield, J. Morris, E.P. Zheleva, D. Hankamer, B. (1997). The structure, function and dynamics of photosystem two. Physiol plantarum, Vol.100 (4), pp. 817-827.  show abstract

Morris, E.P. Hankamer, B. Zheleva, D. Friso, G. Barber, J. (1997). The three-dimensional structure of a photosystem II core complex determined by electron crystallography. Structure, Vol.5 (6), pp. 837-849.  show abstract

Torok, K. Morris, E.P. (1996). Calmodulin dependent protein kinase II structure and interactions with TA-calmodulin. Biophys j, Vol.70 (2), pp. SU144-SU144.

Knupp, C. Chew, M. Morris, E. Squire, J. (1996). Three-Dimensional Reconstruction of a Collagen IV Analogue in the Dogfish Egg Case Wall. J struct biol, Vol.117 (3), pp. 209-221.  show abstract


Morris, E.P. Katayama, E. Squire, J.M. (1994). Evaluation of high-resolution shadowing applied to freeze-fractured, deep-etched particles: 3-D helical reconstruction of shadowed actin filaments. J struct biol, Vol.113 (1), pp. 47-55.  show abstract




MORRIS, E. (1990). MUSCLE REGULATION - ON THE OTHER HAND. Nature, Vol.345 (6271), pp. 116-117.

Morris, E.P. Nneji, G. Squire, J.M. (1990). The three-dimensional structure of the nemaline rod Z-band. J cell biol, Vol.111 (6 Pt 2), pp. 2961-2978.  show abstract

Enchev, R.I. Scott, D.C. da Fonseca, P.C. Schreiber, A. Monda, J.K. Schulman, B.A. Peter, M. Morris, E.P. Structural Basis for a Reciprocal Regulation between SCF and CSN. Cell reports, .

Abascal-Palacios, G. Ramsay, E.P. Beuron, F. Morris, E. Vannini, A. Structural basis of RNA Polymerase III transcription initiation. Nature, .

Knupp, Morris, Squire, The Interacting Head Motif Structure Does Not Explain the X-Ray Diffraction Patterns in Relaxed Vertebrate (Bony Fish) Skeletal Muscle and Insect (Lethocerus) Flight Muscle. Biology, Vol.8 (3), pp. 67-67.  show abstract


Morris, E.Beuron, F.da Fonseca, P. (2014). The Structure Of The Human Hybrid Proteasome, PROTEIN SCIENCE, Vol.23, pp.211-212.

da Fonseca, P.C.Morris, E.P. (2013). Unravelling the structure of the human 26S proteasome: a hybrid approach, Acta Crystallographica Section A Foundations of Crystallography, Vol.69 (a1), p.s36.

Barford, D.Schreiber, A.Stengel, F.Zhang, Z.Enchev, R.Kong, E.Morris, E.P.Robinson, C.V.da Fonseca, P. (2011). Structural basis of the anaphase promoting complex, Acta Crystallographica Section A Foundations of Crystallography, Vol.67 (a1), p.C23.

Schug, Z.T.da Fonseca, P.Morris, E.P.Joseph, S.K. (2007). Molecular characterization of the inositol trisphosphate receptor pore-forming segment, Presented at 51st Annual Meeting of the Biophysical-Society, Baltimore, MD. BIOPHYSICAL JOURNAL, , p.447A.

Fernando, P.L.Taylor, E.Morris, E.P.da Fonseca, P.C.Riley, F.Potter, B.V.Taylor, C.W. (2005). Three dimensional structure of type 1 inositol 1,4,5-trisphosphate (IP3) receptor bound to IP3, Presented at 49th Annual Meeting of the Biopysical-Society, Long Beach, CA. BIOPHYSICAL JOURNAL, Vol.88 (1), pp.331A-332A.

Paul, D.M.Squire, J.M.Morris, E.P. (2005). Visualisation of troponin by single particle analysis of negatively stained electron micrographs, Presented at 49th Annual Meeting of the Biopysical-Society, Long Beach, CA. BIOPHYSICAL JOURNAL, Vol.88 (1), p.359A.

Squire, J.M.Al-Khayat, H.A.Morris, E.P.Kensler, R.W. (2005). Myosin filament structure using single particle analysis, Presented at 49th Annual Meeting of the Biopysical-Society, Long Beach, CA. BIOPHYSICAL JOURNAL, Vol.88 (1), p.632A.

Cantino, M.E.Chew, M.W.Luther, P.K.Morris, E.Squire, J.M. (2002). Structure and nucleotide-dependent changes of thick filaments in relaxed and rigor plaice fin muscle, Presented at Workshop on Coiled-Coils, Collagen, and Co-Proteins, ALPBACH, AUSTRIA. JOURNAL OF STRUCTURAL BIOLOGY, Vol.137 (1-2), pp.164-175.

Hankamer, B.Morris, E.Nield, J.Carne, A.Barber, J. (2001). Subunit positioning and transmembrane helix organisation in the core dimer of photosystem II, Presented at Conference on Structure, Dynamics and Function of Proteins in Biological Membranes, MONTE VERITA, SWITZERLAND. FEBS LETTERS, Vol.504 (3), pp.142-151.

Buchel, C.Morris, E.Barber, J. (1998). Isolation and characterisation of photosystem II complexes for crystallisation, Presented at XIth International Congress on Photosynthesis - Mechanisms and Effects, BUDAPEST, HUNGARY. PHOTOSYNTHESIS: MECHANISMS AND EFFECTS, VOLS I-V, , pp.953-956.

Hankamer, B.Morris, E.P.Barber, J. (1998). Cryoelectron microscopy of photosystem two shows that CP43 and CP47 are located on opposite sides of the D1/D2 reaction center proteins, Presented at XIth International Congress on Photosynthesis - Mechanisms and Effects, BUDAPEST, HUNGARY. PHOTOSYNTHESIS: MECHANISMS AND EFFECTS, VOLS I-V, , pp.957-960.

Hankamer, B.Morris, E.Zheleva, D.Barber, J. (1995). Biochemical characterisation and structural analysis of monomeric and dimeric photosystem II core preparations, Presented at Xth International Photosynthesis Congress, MONTPELLIER, FRANCE. PHOTOSYNTHESIS: FROM LIGHT TO BIOSPHERE, VOL III, , pp.365-368.