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Journal Articles

Young, K. Starling, N. Sadanandam, A. (2020). The molecular biology of pancreatic neuroendocrine neoplasms: Challenges and translational opportunities. Seminars in cancer biology, Vol.61, pp. 132-138.

Cremolini, C. Benelli, M. Fontana, E. Pagani, F. Rossini, D. Fucà, G. Busico, A. Conca, E. Di Donato, S. Loupakis, F. Schirripa, M. Lonardi, S. Borelli, B. Ongaro, E. Eason, K. Morano, F. Casagrande, M. Fassan, M. Sadanandam, A. de Braud, F. Falcone, A. Pietrantonio, F. (2019). Benefit from anti-EGFRs in RAS and BRAF wild-type metastatic transverse colon cancer: a clinical and molecular proof of concept study. Esmo open, Vol.4 (2), pp. e000489-e000489.  show abstract

Fontana, E. Eason, K. Cervantes, A. Salazar, R. Sadanandam, A. (2019). Context matters—consensus molecular subtypes of colorectal cancer as biomarkers for clinical trials. Annals of oncology, Vol.30 (4), pp. 520-527.

Neuzillet, C. Tijeras‐Raballand, A. Ragulan, C. Cros, J. Patil, Y. Martinet, M. Erkan, M. Kleeff, J. Wilson, J. Apte, M. Tosolini, M. Wilson, A.S. Delvecchio, F.R. Bousquet, C. Paradis, V. Hammel, P. Sadanandam, A. Kocher, H.M. (2019). Inter‐ and intra‐tumoural heterogeneity in cancer‐associated fibroblasts of human pancreatic ductal adenocarcinoma. The journal of pathology, Vol.248 (1), pp. 51-65.

Nyamundanda, G. Fontana, E. Sadanandam, A. (2019). Is the tumour microenvironment a critical prognostic factor in early-stage colorectal cancer?. Annals of oncology, Vol.30 (10), pp. 1538-1540.

Ragulan, C. Eason, K. Fontana, E. Nyamundanda, G. Tarazona, N. Patil, Y. Poudel, P. Lawlor, R.T. Del Rio, M. Koo, S.-. Tan, W.-. Sclafani, F. Begum, R. Teixeira Mendes, L.S. Martineau, P. Scarpa, A. Cervantes, A. Tan, I.B. Cunningham, D. Sadanandam, A. (2019). Analytical Validation of Multiplex Biomarker Assay to Stratify Colorectal Cancer into Molecular Subtypes. Scientific reports, Vol.9 (1).

Poudel, P. Nyamundanda, G. Patil, Y. Cheang, M.C. Sadanandam, A. (2019). Heterocellular gene signatures reveal luminal-A breast cancer heterogeneity and differential therapeutic responses. Npj breast cancer, Vol.5 (1).

Heindl, A. Khan, A.M. Rodrigues, D.N. Eason, K. Sadanandam, A. Orbegoso, C. Punta, M. Sottoriva, A. Lise, S. Banerjee, S. Yuan, Y. (2018). Microenvironmental niche divergence shapes BRCA1-dysregulated ovarian cancer morphological plasticity. Nature communications, Vol.9 (1).

Smyth, E.C. Nyamundanda, G. Cunningham, D. Fontana, E. Ragulan, C. Tan, I.B. Lin, S.J. Wotherspoon, A. Nankivell, M. Fassan, M. Lampis, A. Hahne, J.C. Davies, A.R. Lagergren, J. Gossage, J.A. Maisey, N. Green, M. Zylstra, J.L. Allum, W.H. Langley, R.E. Tan, P. Valeri, N. Sadanandam, A. (2018). A seven-Gene Signature assay improves prognostic risk stratification of perioperative chemotherapy treated gastroesophageal cancer patients from the MAGIC trial. Annals of oncology, Vol.29 (12), pp. 2356-2362.

Eason, K. Nyamundanda, G. Sadanandam, A. (2018). polyClustR: defining communities of reconciled cancer subtypes with biological and prognostic significance. Bmc bioinform., Vol.19, pp. 182:1-182:1.

Bijlsma, M.F. Sadanandam, A. Tan, P. Vermeulen, L. (2017). Molecular subtypes in cancers of the gastrointestinal tract. Nature reviews gastroenterology & hepatology, Vol.14 (6), pp. 333-342.

Battersby, N.J. Dattani, M. Rao, S. Cunningham, D. Tait, D. Adams, R. Moran, B.J. Khakoo, S. Tekkis, P. Rasheed, S. Mirnezami, A. Quirke, P. West, N.P. Nagtegaal, I. Chong, I. Sadanandam, A. Valeri, N. Thomas, K. Frost, M. Brown, G. (2017). A rectal cancer feasibility study with an embedded phase III trial design assessing magnetic resonance tumour regression grade (mrTRG) as a novel biomarker to stratify management by good and poor response to chemoradiotherapy (TRIGGER): study protocol for a randomised controlled trial. Trials, Vol.18 (1).

Nyamundanda, G. Poudel, P. Patil, Y. Sadanandam, A. (2017). A Novel Statistical Method to Diagnose, Quantify and Correct Batch Effects in Genomic Studies. Scientific reports, Vol.7 (1).

Fontana, E. Homicsko, K. Eason, K. Sadanandam, A. (2016). Molecular Classification of Colon Cancer: Perspectives for Personalized Adjuvant Therapy. Current colorectal cancer reports, Vol.12 (6), pp. 296-302.

Eason, K. Sadanandam, A. (2016). Molecular or Metabolic Reprograming: What Triggers Tumor Subtypes?. Cancer research, Vol.76 (18), pp. 5195-5200.

Sadanandam, A. Wullschleger, S. Lyssiotis, C.A. Grotzinger, C. Barbi, S. Bersani, S. Korner, J. Wafy, I. Mafficini, A. Lawlor, R.T. Simbolo, M. Asara, J.M. Blaker, H. Cantley, L.C. Wiedenmann, B. Scarpa, A. Hanahan, D. (2015). A Cross-Species Analysis in Pancreatic Neuroendocrine Tumors Reveals Molecular Subtypes with Distinctive Clinical, Metastatic, Developmental, and Metabolic Characteristics. Cancer discovery, Vol.5 (12), pp. 1296-1313.

Guinney, J. Dienstmann, R. Wang, X. de Reyniès, A. Schlicker, A. Soneson, C. Marisa, L. Roepman, P. Nyamundanda, G. Angelino, P. Bot, B.M. Morris, J.S. Simon, I.M. Gerster, S. Fessler, E. De Sousa E Melo, F. Missiaglia, E. Ramay, H. Barras, D. Homicsko, K. Maru, D. Manyam, G.C. Broom, B. Boige, V. Perez-Villamil, B. Laderas, T. Salazar, R. Gray, J.W. Hanahan, D. Tabernero, J. Bernards, R. Friend, S.H. Laurent-Puig, P. Medema, J.P. Sadanandam, A. Wessels, L. Delorenzi, M. Kopetz, S. Vermeulen, L. Tejpar, S. (2015). The consensus molecular subtypes of colorectal cancer. Nature medicine, Vol.21 (11), pp. 1350-1356.

Kapoor, A. Yao, W. Ying, H. Hua, S. Liewen, A. Wang, Q. Zhong, Y. Wu, C.-. Sadanandam, A. Hu, B. Chang, Q. Chu, G.C. Al-Khalil, R. Jiang, S. Xia, H. Fletcher-Sananikone, E. Lim, C. Horwitz, G.I. Viale, A. Pettazzoni, P. Sanchez, N. Wang, H. Protopopov, A. Zhang, J. Heffernan, T. Johnson, R.L. Chin, L. Wang, Y.A. Draetta, G. DePinho, R.A. (2014). Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer. Cell, Vol.158 (1), pp. 185-197.  show abstract

Purohit, A. Sadanandam, A. Myneni, P. Singh, R.K. (2014). Semaphorin 5A mediated cellular navigation: connecting nervous system and cancer. Biochim biophys acta, Vol.1846 (2), pp. 485-493.  show abstract

Bansal, M. Yang, J. Karan, C. Menden, M.P. Costello, J.C. Tang, H. Xiao, G. Li, Y. Allen, J. Zhong, R. Chen, B. Kim, M. Wang, T. Heiser, L.M. Realubit, R. Mattioli, M. Alvarez, M.J. Shen, Y. Gallahan, D. Singer, D. Saez-Rodriguez, J. Xie, Y. Stolovitzky, G. Califano, A. (2014). A community computational challenge to predict the activity of pairs of compounds. Nature biotechnology, Vol.32 (12), pp. 1213-1222.

Costello, J.C. Heiser, L.M. Georgii, E. Gönen, M. Menden, M.P. Wang, N.J. Bansal, M. Ammad-ud-din, M. Hintsanen, P. Khan, S.A. Mpindi, J.-. Kallioniemi, O. Honkela, A. Aittokallio, T. Wennerberg, K. Collins, J.J. Gallahan, D. Singer, D. Saez-Rodriguez, J. Kaski, S. Gray, J.W. Stolovitzky, G. (2014). A community effort to assess and improve drug sensitivity prediction algorithms. Nature biotechnology, Vol.32 (12), pp. 1202-1212.

Sadanandam, A. Wang, X. de Sousa E Melo, F. Gray, J.W. Vermeulen, L. Hanahan, D. Medema, J.P. (2014). Reconciliation of classification systems defining molecular subtypes of colorectal cancer: interrelationships and clinical implications. Cell cycle, Vol.13 (3), pp. 353-357.  show abstract

Sadanandam, A. Lyssiotis, C.A. Homicsko, K. Collisson, E.A. Gibb, W.J. Wullschleger, S. Ostos, L.C. Lannon, W.A. Grotzinger, C. Del Rio, M. Lhermitte, B. Olshen, A.B. Wiedenmann, B. Cantley, L.C. Gray, J.W. Hanahan, D. (2013). A colorectal cancer classification system that associates cellular phenotype and responses to therapy. Nat med, Vol.19 (5), pp. 619-625.  show abstract

Hunter, K.E. Quick, M.L. Sadanandam, A. Hanahan, D. Joyce, J.A. (2013). Identification and characterization of poorly differentiated invasive carcinomas in a mouse model of pancreatic neuroendocrine tumorigenesis. Plos one, Vol.8 (5), p. e64472.  show abstract

Sadanandam, A. Lal, A. Benz, S.C. Eppenberger-Castori, S. Scott, G. Gray, J.W. Spellman, P. Waldman, F. Benz, C.C. (2012). Genomic aberrations in normal tissue adjacent to HER2-amplified breast cancers: field cancerization or contaminating tumor cells?. Breast cancer res treat, Vol.136 (3), pp. 693-703.  show abstract

Heiser, L.M. Sadanandam, A. Kuo, W.-. Benz, S.C. Goldstein, T.C. Ng, S. Gibb, W.J. Wang, N.J. Ziyad, S. Tong, F. Bayani, N. Hu, Z. Billig, J.I. Dueregger, A. Lewis, S. Jakkula, L. Korkola, J.E. Durinck, S. Pepin, F. Guan, Y. Purdom, E. Neuvial, P. Bengtsson, H. Wood, K.W. Smith, P.G. Vassilev, L.T. Hennessy, B.T. Greshock, J. Bachman, K.E. Hardwicke, M.A. Park, J.W. Marton, L.J. Wolf, D.M. Collisson, E.A. Neve, R.M. Mills, G.B. Speed, T.P. Feiler, H.S. Wooster, R.F. Haussler, D. Stuart, J.M. Gray, J.W. Spellman, P.T. (2012). Subtype and pathway specific responses to anticancer compounds in breast cancer. Proc natl acad sci u s a, Vol.109 (8), pp. 2724-2729.  show abstract

Sadanandam, A. Sidhu, S.S. Wullschleger, S. Singh, S. Varney, M.L. Yang, C.-. Ashour, A.E. Batra, S.K. Singh, R.K. (2012). Secreted semaphorin 5A suppressed pancreatic tumour burden but increased metastasis and endothelial cell proliferation. Br j cancer, Vol.107 (3), pp. 501-507.  show abstract

Collisson, E.A. Sadanandam, A. Olson, P. Gibb, W.J. Truitt, M. Gu, S. Cooc, J. Weinkle, J. Kim, G.E. Jakkula, L. Feiler, H.S. Ko, A.H. Olshen, A.B. Danenberg, K.L. Tempero, M.A. Spellman, P.T. Hanahan, D. Gray, J.W. (2011). Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy. Nat med, Vol.17 (4), pp. 500-503.  show abstract

Sadanandam, A. Futakuchi, M. Lyssiotis, C.A. Gibb, W.J. Singh, R.K. (2011). A cross-species analysis of a mouse model of breast cancer-specific osteolysis and human bone metastases using gene expression profiling. Bmc cancer, Vol.11, p. 304.  show abstract

Sadanandam, A. Rosenbaugh, E.G. Singh, S. Varney, M. Singh, R.K. (2010). Semaphorin 5A promotes angiogenesis by increasing endothelial cell proliferation, migration, and decreasing apoptosis. Microvasc res, Vol.79 (1), pp. 1-9.  show abstract

Sadanandam, A. Varney, M.L. Singh, S. Ashour, A.E. Moniaux, N. Deb, S. Lele, S.M. Batra, S.K. Singh, R.K. (2010). High gene expression of semaphorin 5A in pancreatic cancer is associated with tumor growth, invasion and metastasis. Int j cancer, Vol.127 (6), pp. 1373-1383.  show abstract

Loss, L.A. Sadanandam, A. Durinck, S. Nautiyal, S. Flaucher, D. Carlton, V.E. Moorhead, M. Lu, Y. Gray, J.W. Faham, M. Spellman, P. Parvin, B. (2010). Prediction of epigenetically regulated genes in breast cancer cell lines. Bmc bioinformatics, Vol.11, p. 305.  show abstract

Singh, S. Sadanandam, A. Varney, M.L. Nannuru, K.C. Singh, R.K. (2010). Small interfering RNA-mediated CXCR1 or CXCR2 knock-down inhibits melanoma tumor growth and invasion. Int j cancer, Vol.126 (2), pp. 328-336.  show abstract

Hu, Z. Huang, G. Sadanandam, A. Gu, S. Lenburg, M.E. Pai, M. Bayani, N. Blakely, E.A. Gray, J.W. Mao, J.-. (2010). The expression level of HJURP has an independent prognostic impact and predicts the sensitivity to radiotherapy in breast cancer. Breast cancer res, Vol.12 (2), p. R18.  show abstract

Futakuchi, M. Nannuru, K.C. Varney, M.L. Sadanandam, A. Nakao, K. Asai, K. Shirai, T. Sato, S.-. Singh, R.K. (2009). Transforming growth factor-beta signaling at the tumor-bone interface promotes mammary tumor growth and osteoclast activation. Cancer sci, Vol.100 (1), pp. 71-81.  show abstract

Singh, S. Sadanandam, A. Nannuru, K.C. Varney, M.L. Mayer-Ezell, R. Bond, R. Singh, R.K. (2009). Small-molecule antagonists for CXCR2 and CXCR1 inhibit human melanoma growth by decreasing tumor cell proliferation, survival, and angiogenesis. Clin cancer res, Vol.15 (7), pp. 2380-2386.  show abstract

Singh, S. Nannuru, K. Sadanandam, A. Varney, M. Singh, R. (2009). Expression of CXCR1 and CXCR2 enhances human melanoma tumorigenesis, growth and invasion. Cancer research, Vol.69.

Kuo, W.-. Das, D. Ziyad, S. Bhattacharya, S. Gibb, W.J. Heiser, L.M. Sadanandam, A. Fontenay, G.V. Hu, Z. Wang, N.J. Bayani, N. Feiler, H.S. Neve, R.M. Wyrobek, A.J. Spellman, P.T. Marton, L.J. Gray, J.W. (2009). A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047. Bmc med, Vol.7, p. 77.  show abstract

Singh, S. Nannuru, K.C. Sadanandam, A. Varney, M.L. Singh, R.K. (2009). CXCR1 and CXCR2 enhances human melanoma tumourigenesis, growth and invasion. Br j cancer, Vol.100 (10), pp. 1638-1646.  show abstract

Nannuru, K.C. Futakuchi, M. Sadanandam, A. Wilson, T.J. Varney, M.L. Myers, K.J. Li, X. Marcusson, E.G. Singh, R.K. (2009). Enhanced expression and shedding of receptor activator of NF-kappaB ligand during tumor-bone interaction potentiates mammary tumor-induced osteolysis. Clin exp metastasis, Vol.26 (7), pp. 797-808.  show abstract

Sadanandam, A. Varney, M.L. Singh, R.K. (2008). Identification of semaphorin 5A interacting protein by applying apriori knowledge and peptide complementarity related to protein evolution and structure. Genomics proteomics bioinformatics, Vol.6 (3-4), pp. 163-174.  show abstract

Wilson, T.J. Nannuru, K.C. Futakuchi, M. Sadanandam, A. Singh, R.K. (2008). Cathepsin G enhances mammary tumor-induced osteolysis by generating soluble receptor activator of nuclear factor-kappaB ligand. Cancer res, Vol.68 (14), pp. 5803-5811.  show abstract

Sadanandam, A. Pal, S.N. Ziskovsky, J. Hegde, P. Singh, R.K. (2008). MCAM: a database to accelerate the identification of functional cell adhesion molecules. Cancer inform, Vol.6, pp. 47-50.  show abstract

Ashour, A.E. Lin, X. Wang, X. Turnquist, H.R. Burns, N.M. Tuli, A. Sadanandam, A. Suleiman, K. Singh, R.K. Talmadge, J.E. Solheim, J.C. (2007). CCL21 is an effective surgical neoadjuvant for treatment of mammary tumors. Cancer biol ther, Vol.6 (8), pp. 1206-1210.  show abstract

Singh, S. Sadanandam, A. Singh, R.K. (2007). Chemokines in tumor angiogenesis and metastasis. Cancer metastasis rev, Vol.26 (3-4), pp. 453-467.  show abstract

Sadanandam, A. Varney, M.L. Kinarsky, L. Ali, H. Mosley, R.L. Singh, R.K. (2007). Identification of functional cell adhesion molecules with a potential role in metastasis by a combination of in vivo phage display and in silico analysis. Omics, Vol.11 (1), pp. 41-57.  show abstract

Sadanandam, A. Sadanandam, A. Collisson, E. Gibb, W. Hanahan, D. Gray, J. Identification of Molecular Subtypes in Pancreatic Adenocarcinoma with Predictive and Prognostic Importance. Protocol exchange, .

Sadanandam, A. Consensus gene expression subtypes of epithelial tumours. Biorxiv (the preprint server for biology), .

Vlachogiannis, G. Hedayat, S. Vatsiou, A. Jamin, Y. Fernandez Mateos, J. Khan, K. Lampis, A. Eason, K. Burke, R. Rata, M. Koh, D.-. Tunariu, N. Collins, D. Hulkki, S. Ragulan, C. Spiteri Sagastume, I. Moorcraft, S.Y. Chau, I. Rao, S. Watkins, D. Fotiadis, N. Bali, M. Darvish Damavandi, M. Lote, H. Eltahir, Z. Smyth, L. Begum, R. Clarke, P. Hahne, J. Dowsett, M. De Bono, J. Workman, P. Sadanandam, A. Eccles, S. Starling, N. Braconi, C. Sottoriva, A. Robinson, S. Cunningham, D. Valeri, N. Patient-derived organoids model treatment response of metastatic gastrointestinal cancers. Science, .

Wagner, S. Vlachogiannis, G. De Haven Brandon, A. Valenti, M. Box, G. Jenkins, L. Mancusi, C. Self, A. Manodoro, F. Assiotis, I. Robinson, P. Chauhan, R. Rust, A. Matthews, N. Eason, K. Khan, K. Starling, N. Cunningham, D. Sadanandam, A. Isacke, C. Kirkin, V. Valeri, N. Whittaker, S. Suppression of interferon gene expression overcomes resistance to MEK inhibition in KRAS-mutant colorectal cancer. Oncogene, .

Dillon, M. ATR inhibition potentiates the radiation induced inflammatory tumor microenvironment. Clinical cancer research, .

Woolston, A. Khan, K. Spain, G. Barber, L. Griffiths, B. Gonzalez-Exposito, R. Hornsteiner, L. Punta, M. Patil, Y. Newey, A. Mansukhani, S. Davies, M. Furness, A. Sclafani, F. Peckitt, C. Jimanez, M. Kouvelakis, K. Ranftl, R. Begum, R. Rana, I. Thomas, J. Bryant, A. Quezada, S. Wotherspoon, A. Khan, N. Fotiadis, N. Marafioti, T. Powles, T. Lise, S. Calvo, F. Guettler, S. von Loga, K. Rao, S. Watkins, D. Starling, N. Chau, I. Sadanandam, A. Cunningham, D. Gerlinger, M. Genomic and transcriptomic determinants of therapy resistance and immune landscape evolution during anti-EGFR treatment in colorectal cancer. Cancer cell, .

Sadanandam, A. Bopp, T. Dixit, S. Knapp, D.J. Emperumal, C.P. Rajalingam, K. Melcher, A. Kannan, N. A blood-based comprehensive and systems-level analysis of disease stages, immune regulation and symptoms in COVID-19 patients. , .  show abstract

Book Chapters

Collisson, E.A. Sadanandam, A. Spellman, P.T. Gray, J.W. (2009). Cancer genome aberrations: measure, causes, and consequences. In Holland-Frei Cancer Medicine, (Ed.), . Eight (pp. 359-363). BC Decker Publications in collaboration with AACR.

Sadanandam, A. GIbb, W. Singh, R.K. Bioinformatics analysis to identify cell adhesion molecules in cancer. In Preedy, V.R. (Ed.), Modern Insights into Disease from Molecules to Man. Science Publishers.


Poudel, P.Neuzillet, C.Kocher, H.Sadanandam, A. (2019). Abstract 3094: Reclassification of pancreatic adenocarcinoma with distinct fibroblast and immune characteristics and therapeutic targets, Presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, Clinical Research (Excluding Clinical Trials), .

Fontana, E.Wilkins, A.Patil, Y.Nyamundanda, G.Ragulan, C.Mansfield, D.Kingston, J.Errington-Mais, F.West, N.Bottomley, D.Downs, J.Demaria, S.Harrington, K.J.Melcher, A.Sadanandam, A. (2019). Characterization of chemoradiation-induced changes in immune cells and targets for personalized therapy in locally advanced rectal cancer (LARC)., Journal of Clinical Oncology, Vol.37 (4_suppl), p.589.

Sclafani, F.Cascione, L.Cunningham, D.Young, K.Carotenuto, P.Fassan, M.Salati, M.Lanese, A.Berenguer Pina, J.Kouvelakis, K.Vendrell, I.Said-Huntingford, I.Previdi, M.Begum, R.Gillbanks, A.Hedayat, S.Sadanandam, A.Lampis, A.Hahne, J.Valeri, N.Chau, I.Braconi, C. (2019). Identification of a nanostring signature that differentiates early pancreatic cancers according to stromal composition and predicts clinical outcome, Annals of Oncology, Vol.30, pp.iv110-iv111.

Fontana, E.Nyamundanda, G.Cunningham, D.Jonker, D.J.Siu, L.L.Tu, D.Sclafani, F.Eason, K.V.Ragulan, C.Hulkki-Wilson, S.Loree, J.M.Giordano, M.Lawrence, P.V.Shapiro, J.Cremolini, C.Starling, N.Pietrantonio, F.Trusolino, L.O'Callaghan, C.Sadanandam, A. (2019). Association between transit-amplifying signature and outcomes of patients treated with anti-epidermal growth factor receptor (EGFR) therapy in colorectal cancer, ANNALS OF ONCOLOGY, Vol.30, pp.201-+.

Desai, K.Ragulan, C.Lawrence, P.V.Wullschleger, S.Tichet, M.L.Box, G.Fontana, E.Young, K.Larkin, J.M.Hanahan, D.Cunningham, D.Starling, N.Sadanandam, A. (2019). A personalised approach for anti-GITR-based immunotherapy in preclinical models of pancreatic ductal adenocarcinoma, ANNALS OF ONCOLOGY, Vol.30, p.53.

Sadanandam, A.Young, K.Lawlor, R.Patil, Y.Ragulan, C.Luchini, C.Cantu, C.Mansfield, D.Melcher, A.Cunningham, D.Starling, N.Scarpa, A. (2019). Immune Characteristics of Pancreatic Neuroendocrine Tumors According to Grade and Molecular Subtypes, NEUROENDOCRINOLOGY, Vol.108, p.34.

Chua, C.W.Cukuroglu, E.Fontana, E.Koo, S.L.Yeong, J.P.Nguyen, A.Sanborn, J.Z.Benz, S.Tan, E.J.Mathew, R.Toh, E.-.Ng, S.B.Lim, T.K.Skanderup, A.J.Rabizadeh, S.Sadanandam, A.Göke, J.Tan, I.B. (2018). Abstract 5693: Tumor whole-transcriptome sequencing and multiplex immunohistochemistry of immune cell populations in 158 Asian colorectal cancers, Presented at Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL, Immunology, .

Wagner, S.Vlachogiannis, G.Brandon, A.D.Valenti, M.Box, G.Jenkins, L.Mancusi, C.Self, A.Chauhan, R.Rust, A.Matthews, N.Eason, K.Sadanandam, A.Isacke, C.Kirkin, V.Valeri, N.Whittaker, S.R. (2018). Abstract LB-094: Suppression of inflammatory gene expression overcomes resistance to MEK inhibition in KRAS-mutant colorectal cancer, Presented at Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL, Experimental and Molecular Therapeutics, .

Khan, K.H.Woolston, A.Spain, G.Barber, L.Patil, Y.Griffiths, B.GonzalezExposito, R.Mansukhani, S.Davies, M.Rao, S.Watkins, D.Sclafani, F.Suntharanathan, J.Peckitt, C.Begum, R.Rana, I.Thomas, J.Oates, J.Bryant, A.Wotherspoon, A.Fotiadis, N.Khan, N.Guettler, S.Loga, K.V.Starling, N.Chau, I.Sadanandam, A.Cunningham, D.Gerlinger, M. (2018). Abstract 4339: Molecular subtypes and novel genetic mechanisms of primary and acquired anti-EGFR resistance in colorectal cancer in the Prospect C biomarker trial, Presented at Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL, Molecular and Cellular Biology / Genetics, .

Carotenuto, P.Zito, D.Previdi, M.C.Raj, M.Fassan, M.Lampis, A.Scalafani, F.Lanese, A.Said-Huntingford, I.Hahne, J.C.Young, K.Begum, R.Ethiar, Z.Wotherspoon, A.Starling, N.Sadanandam, A.Cunningham, D.Chau, I.Workman, P.Chopra, R.Valeri, N.Braconi, C. (2018). Abstract 4977: MIR1307 mediates pancreatic cancer resistance to FOLFIRINOX chemotherapy by affecting response to DNA damage, Presented at Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL, Molecular and Cellular Biology / Genetics, .

Damavandi, M.D.Vlachogiannis, G.Nyamundanda, G.Lampis, A.Parkes, H.Hedayat, S.Hahne, J.Fassan, M.Sadanandam, A.Sansom, O.Valeri, N. (2018). Defining microRNA mediated regulation of CD157 involved in colon cancer progression, BRITISH JOURNAL OF CANCER, Vol.119 (11), pp.21-22.

Sadanandam, A.Young, K.Nyamundanda, G.Ragulan, C.Lawlor, R.Scarpa, A. (2018). Development of Multiplex Biomarker Assay to Subtype Pancreatic Neuroendocrine Tumors (PanNETs) with Distinct Prognosis and Mutations, NEUROENDOCRINOLOGY, Vol.106, p.164.

Cros, J.Bucau, M.Raffenne, J.Soukeur, M.Dumont, F.De Koning, Mestier, L.Hentic, O.Sauvanet, A.Sadanandam, A.Ruszniewski, P.Couvelard, A. (2018). Mitochondrial or Aerobic Glycolysis Oriented Metabolism May Define Pancreatic Neuroendocrine Tumors (PanNET) Resistance to mTOR-Targeting Therapies, NEUROENDOCRINOLOGY, Vol.106, p.27.

Ragulan, C.Poudel, P.Young, K.Nyamundanda, G.Lawlor, R.T.Scarpa, A.Sadanandam, A. (2017). Undiscovered immune heterogeneity in pancreatic adenocarcinoma (PDAC), ANNALS OF ONCOLOGY, Vol.28.

Neuzillet, C.Tijeras-Raballand, A.Sadanandam, A.Bourgoin, P.Bourget, P.Poudel, P.Serova, M.Gramont, A.D.Ruszniewski, P.Paradis, V.Raymond, E.Cros, J.Hammel, P. (2016). Abstract B57: Effects of MEK inhibition alone or in combination with PI3K-mTOR pathway inhibitors in pancreatic ductal adenocarcinoma in vitro and on an innovative ex vivo fresh tumor tissue culture model, Presented at Abstracts: AACR Special Conference on Pancreatic Cancer: Advances in Science and Clinical Care; May 12-15, 2016; Orlando, FL, Molecular Drivers of Pancreatic Cancer Biology and Metastasis, .

Kapoor, A.Yao, W.Ying, H.Hua, S.Liewen, A.Sadanandam, A.Al-Khalil, R.Viale, A.Pettazzoni, P.Sanchez, N.Protopopov, A.Zhang, J.Heffernan, T.Johnson, R.L.Chin, L.Wang, Y.A.Draetta, G.DePinho, R.A. (2015). Abstract A94: Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer, Presented at Abstracts: AACR Special Conference on Pancreatic Cancer: Innovations in Research and Treatment; May 18-21, 2014; New Orleans, LA, New Therapies, .

Guinney, J.Dienstmann, R.Wang, Reynies, A.Schlicker, A.Soneson, C.Marisa, L.Roepman, P.Nyamundanda, G.Angelino, P.Bot, B.Morris, J.S.Simon, I.Gerster, S.Fessler, Sousa e Melo, F.Missiaglia, E.Ramay, H.Barras, D.Homicsko, K.Maru, D.Manyam, G.Broom, B.Boige, V.Laderas, T.Salazar, R.Gray, J.W.Tabernero, J.Bernards, R.Friend, S.Laurent-Puig, P.Medema, J.P.Sadanandam, A.Wessels, L.Delorenzi, M.Kopetz, S.Vermeulen, L.Tejpar, S. (2015). Abstract 603: Consensus molecular subtyping through a community of experts advances unsupervised gene expression-based disease classification and facilitates clinical translation, Presented at Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA, Clinical Research (Excluding Clinical Trials), .

Darvish Damavandi, M.Braconi, C.Cascione, L.Lampis, A.Hahne, J.Murgia, C.Ghidini, M.Nyamundanda, G.Sadanandam, A.Croce, C.Sansom, O.Valeri, N. (2015). Abstract 3083: Global gene expression profiling of mice tumor-derived organoids identifies key microRNAs and metabolic genes involved in CRC progression, Presented at Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA, Molecular and Cellular Biology, .


Kapoor, A.Yao, W.Ying, H.Hua, S.Liewen, A.Wang, Q.Zhong, Y.Wu, C.-.Sadanandam, A.Hu, B.Chang, Q.Chu, G.Al-Khalil, R.Jiang, S.Xia, H.Fletcher-Sananikone, E.Lim, C.Horwitz, G.Viale, A.Pettazzoni, P.Sanchez, N.Wang, H.Protopopov, A.Zhang, J.Heffernan, T.Johnson, R.Chin, L.Wang, A.Draetta, G.DePinho, R. (2014). Abstract PR01: Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer, Presented at Abstracts: AACR Special Conference on RAS Oncogenes: From Biology to Therapy; February 24-27, 2014; Lake Buena Vista, FL, Models of RAS-driven Cancers, .

Dienstmann, R.Guinney, J.Delorenzi, M.De Reynies, A.Roepman, P.Sadanandam, A.Vermeulen, L.Schlicker, A.Missiaglia, E.Soneson, C.Marisa, L.Homicsko, K.Wang, X.Simon, I.Laurent-Puig, P.Wessels, L.F.Medema, J.P.Kopetz, S.Friend, S.H.Tejpar, S.Subtyping, C.C. (2014). Colorectal Cancer Subtyping Consortium (CRCSC) identification of a consensus of molecular subtypes., JOURNAL OF CLINICAL ONCOLOGY, Vol.32 (15).

Sadanandam, A.Hanahan, D. (2013). Abstract SY18-02: Molecular genetic subtypes of pancreas and colon cancer: Phenotypes and potential therapeutic significance., Presented at Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC, Molecular and Cellular Biology, .

Sadanandam, A.Wullschleger, S.Spellman, P.Hanahan, D.Gray, J.W. (2012). Abstract LB-403: Recurrent fusion transcripts in breast cancer, Presented at Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL, Molecular and Cellular Biology, .

Sadanandam, A.Collisson, E.A.Olson, P.Gibb, W.J.Truitt, M.Olshen, A.Tempero, M.A.Spellman, P.T.Hanahan, D.Gray, J.W. (2011). Abstract LB-24: Molecular subtypes of pancreatic adenocarcinoma with different biological characteristics and therapeutical responses, Presented at Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL, Cellular and Molecular Biology, .

Sadanandam, A.Gibb, W.Heiser, L.Kuo, W.-.Spellman, P.Gray, J. (2009). Integrated omic analysis of breast cancer cell lines, CANCER RESEARCH, Vol.69.

Sadanandam, A.Varney, M.L.Hollingsworth, M.A.Batra, S.K.Sretavan, D.W.Puschel, A.W.Singh, R.K. (2007). Expression of semaphorin 5A in metastatic pancreatic cancer cells and modulates cellular proliferation, invasion and tumor growth and metastasis, CLINICAL & EXPERIMENTAL METASTASIS, Vol.24 (4), pp.256-257.

Singh, R.Varney, M.Sadanandam, A.Solheim, J.Talmadge, J. (2007). Vascular endothelial growth factor (VEGF)-C and VEGF receptor-3 signaling directly and indirectly modulates murine mammary tumor growth and metastasis, CLINICAL & EXPERIMENTAL METASTASIS, Vol.24 (4), p.232.

Varney, M.L.Sadanandam, A.Solheim, J.C.Talmadge, J.E.Singh, R.K. (2006). VEGFR3 antagonist (MAZ51) directly and indirectly inhibits murine mammary tumor growth and metastasis, CANCER RESEARCH, Vol.66 (8).

Futakuchi, M.Varney, M.L.Sadanandam, A.Nakao, K.Asai, K.Shirai, T.Singh, R.K. (2006). TGF-beta directly and indirectly promote mammary tumor growth in the bone microenvironment by increasing osteoclastgenesis, CANCER RESEARCH, Vol.66 (8).

Sadanandam, A.Varney, M.L.Hollingsworth, M.A.Batra, S.K.Sretavan, D.W.Pueschel, A.W.Singh, R.K. (2006). SEMA5A expression in pancreatic cancer is associated with metastases and regulates pancreatic cancer cell proliferation and their adherence in different microenvironment, CANCER RESEARCH, Vol.66 (8).

Sadanandam, A.Futakuchi, M.Varney, M.Qiu, F.Singh, R. (2006). Gene expression profiling using a unique murine mammary tumor model reveal role of novel genes regulating tumor-stromal interaction in mammary tumor-induced osteolysis, FASEB JOURNAL, Vol.20 (4), p.A222.

Huang, X.Ali, H.H.Sadanandam, A.Singh, R.K. (2005). Protein Motif Searching Through Similar Enriched Parikh Vector Identification., BIBE, , pp.285-289.

Huang, X.Ali, H.H.Sadanandam, A.Singh, R.K. (2004). SRPVS: A New Motif Searching Algorithm for Protein Analysis., CSB, , pp.674-675.

Sadanandam, A.Varney, M.L.Singh, R.K. (2004). High-Throughput Computational and Experimental Biology Strategy in Identifying Tumor Expressing CAMs., CSB, , pp.450-451.