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Barry, P., Vatsiou, A., Spiteri, I., Nichol, D., Cresswell, G.D., Acar, A., Trahearn, N., Hrebien, S., Garcia-Murillas, I., Chkhaidze, K., et al. (2018). The Spatiotemporal Evolution of Lymph Node Spread in Early Breast Cancer. Clin cancer res, Vol.24 (19), pp. 4763-4770.  show abstract

Sottoriva, A. (2018). Divergent adaptation in thyroid cancers. Ann oncol, Vol.29 (6), p. 1353.

Williams, M.J., Werner, B., Barnes, C.P., Graham, T.A. & Sottoriva, A. (2018). Reply: Is the evolution of tumors Darwinian or non-Darwinian?. National science review, Vol.5 (1), pp. 17-19.

Williams, M.J., Werner, B., Heide, T., Curtis, C., Barnes, C.P., Sottoriva, A. & Graham, T.A. (2018). Quantification of subclonal selection in cancer from bulk sequencing data. Nat genet, Vol.50 (6), pp. 895-903.  show abstract

Caravagna, G., Giarratano, Y., Ramazzotti, D., Tomlinson, I., Graham, T.A., Sanguinetti, G. & Sottoriva, A. (2018). Detecting repeated cancer evolution from multi-region tumor sequencing data. Nat methods, Vol.15 (9), pp. 707-714.  show abstract

Cross, W., Kovac, M., Mustonen, V., Temko, D., Davis, H., Baker, A.-., Biswas, S., Arnold, R., Chegwidden, L., Gatenbee, C., et al. (2018). The evolutionary landscape of colorectal tumorigenesis. Nat ecol evol, Vol.2 (10), pp. 1661-1672.  show abstract

Khan, K.H., Cunningham, D., Werner, B., Vlachogiannis, G., Spiteri, I., Heide, T., Mateos, J.F., Vatsiou, A., Lampis, A., Damavandi, M.D., et al. (2018). Longitudinal Liquid Biopsy and Mathematical Modeling of Clonal Evolution Forecast Time to Treatment Failure in the PROSPECT-C Phase II Colorectal Cancer Clinical Trial. Cancer discov, Vol.8 (10), pp. 1270-1285.  show abstract

Williams, M.J., Werner, B., Heide, T., Barnes, C.P., Graham, T.A. & Sottoriva, A. (2018). Reply to 'Revisiting signatures of neutral tumor evolution in the light of complexity of cancer genomic data'. Nat genet, .

Heindl, A., Khan, A.M., Rodrigues, D.N., Eason, K., Sadanandam, A., Orbegoso, C., Punta, M., Sottoriva, A., Lise, S., Banerjee, S., et al. (2018). Microenvironmental niche divergence shapes BRCA1-dysregulated ovarian cancer morphological plasticity. Nat commun, Vol.9 (1), p. 3917.  show abstract

Graham, T.A. & Sottoriva, A. (2017). Measuring cancer evolution from the genome. J pathol, Vol.241 (2), pp. 183-191.  show abstract

Sottoriva, A., Barnes, C.P. & Graham, T.A. (2017). Catch my drift? Making sense of genomic intra-tumour heterogeneity. Biochim biophys acta rev cancer, Vol.1867 (2), pp. 95-100.  show abstract

Sun, R., Hu, Z., Sottoriva, A., Graham, T.A., Harpak, A., Ma, Z., Fischer, J.M., Shibata, D. & Curtis, C. (2017). Between-region genetic divergence reflects the mode and tempo of tumor evolution. Nat genet, Vol.49 (7), pp. 1015-1024.  show abstract

Williams, M.J., Werner, B., Barnes, C.P., Graham, T.A. & Sottoriva, A. (2017). Reply: Uncertainties in tumor allele frequencies limit power to infer evolutionary pressures. Nat genet, Vol.49 (9), pp. 1289-1291.

Lipinski, K.A., Barber, L.J., Davies, M.N., Ashenden, M., Sottoriva, A. & Gerlinger, M. (2016). Cancer Evolution and the Limits of Predictability in Precision Cancer Medicine. Trends cancer, Vol.2 (1), pp. 49-63.  show abstract

Williams, M.J., Werner, B., Barnes, C.P., Graham, T.A. & Sottoriva, A. (2016). Identification of neutral tumor evolution across cancer types. Nat genet, Vol.48 (3), pp. 238-244.  show abstract

Williams, M.J., Werner, B., Graham, T.A. & Sottoriva, A. (2016). Functional versus non-functional intratumor heterogeneity in cancer. Mol cell oncol, Vol.3 (4), p. e1162897.  show abstract

Piccirillo, S.G., Spiteri, I., Sottoriva, A., Touloumis, A., Ber, S., Price, S.J., Heywood, R., Francis, N.-., Howarth, K.D., Collins, V.P., et al. (2015). Contributions to drug resistance in glioblastoma derived from malignant cells in the sub-ependymal zone. Cancer res, Vol.75 (1), pp. 194-202.  show abstract

Gubernator, M., Slater, S.C., Spencer, H.L., Spiteri, I., Sottoriva, A., Riu, F., Rowlinson, J., Avolio, E., Katare, R., Mangialardi, G., et al. (2015). Epigenetic profile of human adventitial progenitor cells correlates with therapeutic outcomes in a mouse model of limb ischemia. Arterioscler thromb vasc biol, Vol.35 (3), pp. 675-688.  show abstract

Sottoriva, A., Kang, H., Ma, Z., Graham, T.A., Salomon, M.P., Zhao, J., Marjoram, P., Siegmund, K., Press, M.F., Shibata, D., et al. (2015). A Big Bang model of human colorectal tumor growth. Nat genet, Vol.47 (3), pp. 209-216.  show abstract

Piccirillo, S.G., Sottoriva, A. & Watts, C. (2015). The role of sub-ventricular zone in gliomagenesis. Aging (albany ny), Vol.7 (10), pp. 738-739.

Kang, H., Salomon, M.P., Sottoriva, A., Zhao, J., Toy, M., Press, M.F., Curtis, C., Marjoram, P., Siegmund, K. & Shibata, D., et al. (2015). Many private mutations originate from the first few divisions of a human colorectal adenoma. J pathol, Vol.237 (3), pp. 355-362.  show abstract

Ellis, H.P., Greenslade, M., Powell, B., Spiteri, I., Sottoriva, A. & Kurian, K.M. (2015). Current Challenges in Glioblastoma: Intratumour Heterogeneity, Residual Disease, and Models to Predict Disease Recurrence. Front oncol, Vol.5, p. 251.  show abstract

Sottoriva, A., Spiteri, I., Shibata, D., Curtis, C. & Tavaré, S. (2013). Single-molecule genomic data delineate patient-specific tumor profiles and cancer stem cell organization. Cancer res, Vol.73 (1), pp. 41-49.  show abstract

Sottoriva, A., Spiteri, I., Piccirillo, S.G., Touloumis, A., Collins, V.P., Marioni, J.C., Curtis, C., Watts, C. & Tavaré, S. (2013). Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics. Proc natl acad sci u s a, Vol.110 (10), pp. 4009-4014.  show abstract

Dvinge, H., Git, A., Gräf, S., Salmon-Divon, M., Curtis, C., Sottoriva, A., Zhao, Y., Hirst, M., Armisen, J., Miska, E.A., et al. (2013). The shaping and functional consequences of the microRNA landscape in breast cancer. Nature, Vol.497 (7449), pp. 378-382.  show abstract

Vermeulen, L., Morrissey, E., van der Heijden, M., Nicholson, A.M., Sottoriva, A., Buczacki, S., Kemp, R., Tavaré, S. & Winton, D.J. (2013). Defining stem cell dynamics in models of intestinal tumor initiation. Science, Vol.342 (6161), pp. 995-998.  show abstract

Ageron, M., Aguilar, J.A., Al Samarai, I., Albert, A., Ameli, F., André, M., Anghinolfi, M., Anton, G., Anvar, S., Ardid, M., et al. (2011). ANTARES: The first undersea neutrino telescope. Nuclear instruments and methods in physics research section a: accelerators, spectrometers, detectors and associated equipment, Vol.656, pp. 11-38.  show abstract

Sottoriva, A., Vermeulen, L. & Tavaré, S. (2011). Modeling Evolutionary Dynamics of Epigenetic Mutations in Hierarchically Organized Tumors. Plos computational biology, Vol.7.

Sottoriva, A., Verhoeff, J.J., Borovski, T., McWeeney, S.K., Naumov, L., Medema, J.P., Sloot, P.M. & Vermeulen, L. (2010). Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity. Cancer res, Vol.70 (1), pp. 46-56.  show abstract

Sottoriva, A., Sloot, P.M., Medema, J.P. & Vermeulen, L. (2010). Exploring cancer stem cell niche directed tumor growth. Cell cycle, Vol.9 (8), pp. 1472-1479.  show abstract

Sottoriva, A. & Tavaré, S. (2010). Integrating approximate Bayesian computation with complex agent-based models for cancer research. Compstat 2010 - proceedings in computational statistics, eds. saporta g & lechevallier y. springer, physica verlag, , pp. 57-66.

Portegies Zwart, S., McMillan, S., Harfst, S., Groen, D., Fujii, M., Nualláin, B.Ó., Glebbeek, E., Heggie, D., Lombardi, J., Hut, P., et al. (2009). A multiphysics and multiscale software environment for modeling astrophysical systems. New astronomy, Vol.14, pp. 369-378.  show abstract

Lote, H., Spiteri, I., Ermini, L., Vatsiou, A., Roy, A., McDonald, A., Maka, N., Balsitis, M., Bose, N., Simbolo, M., et al. Carbon dating cancer: defining the chronology of metastatic progression in colorectal cancer. Ann oncol, Vol.28 (6), pp. 1243-1249.  show abstract

Barry, P., Vatsiou, A., Spiteri Sagastume, I., Nichol, D., Cresswell, G., Acar, A., Trahearn, N., Hrebien, S., Garcia-Murillas, I., Chkhaidze, K., et al. The spatio-temporal evolution of lymph node spread in early breast cancer. Clinical cancer research, .

Werner, B. & Sottoriva, A. Variation of mutational burden in healthy human tissues suggests non-random strand segregation and allows measuring somatic mutation rates. Plos comput biol, Vol.14 (6), p. e1006233.  show abstract

Vlachogiannis, G., Hedayat, S., Vatsiou, A., Jamin, Y., Fernández-Mateos, J., Khan, K., Lampis, A., Eason, K., Huntingford, I., Burke, R., et al. Patient-derived organoids model treatment response of metastatic gastrointestinal cancers. Science, Vol.359 (6378), pp. 920-926.  show abstract

Baker, A.-., Huang, W., Wang, X.-., Jansen, M., Ma, X.-., Kim, J., Anderson, C.M., Wu, X., Pan, L., Su, N., et al. Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution. Nat commun, Vol.8 (1), p. 1998.  show abstract

Maley, C.C., Aktipis, A., Graham, T.A., Sottoriva, A., Boddy, A.M., Janiszewska, M., Silva, A.S., Gerlinger, M., Yuan, Y., Pienta, K.J., et al. Classifying the evolutionary and ecological features of neoplasms. Nat rev cancer, Vol.17 (10), pp. 605-619.  show abstract

Werner, B., Traulsen, A., Sottoriva, A. & Dingli, D. Detecting truly clonal alterations from multi-region profiling of tumours. Sci rep, Vol.7, p. 44991.  show abstract

Eskilsson, E., Rosland, G.V., Talasila, K.M., Knappskog, S., Keunen, O., Sottoriva, A., Foerster, S., Solecki, G., Taxt, T., Jirik, R., et al. EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation. Neuro oncol, Vol.18 (12), pp. 1644-1655.  show abstract

Werner, B., Scott, J.G., Sottoriva, A., Anderson, A.R., Traulsen, A. & Altrock, P.M. The Cancer Stem Cell Fraction in Hierarchically Organized Tumors Can Be Estimated Using Mathematical Modeling and Patient-Specific Treatment Trajectories. Cancer res, Vol.76 (7), pp. 1705-1713.  show abstract

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