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Hänsel-Hertsch, R. Simeone, A. Shea, A. Hui, W.W. Zyner, K.G. Marsico, G. Rueda, O.M. Bruna, A. Martin, A. Zhang, X. Adhikari, S. Tannahill, D. Caldas, C. Balasubramanian, S. (2020). Landscape of G-quadruplex DNA structural regions in breast cancer. Nat genet, Vol.52 (9), pp. 878-883.  show abstract

Dev, H. Chiang, T.-. Lescale, C. de Krijger, I. Martin, A.G. Pilger, D. Coates, J. Sczaniecka-Clift, M. Wei, W. Ostermaier, M. Herzog, M. Lam, J. Shea, A. Demir, M. Wu, Q. Yang, F. Fu, B. Lai, Z. Balmus, G. Belotserkovskaya, R. Serra, V. O’Connor, M.J. Bruna, A. Beli, P. Pellegrini, L. Caldas, C. Deriano, L. Jacobs, J.J. Galanty, Y. Jackson, S.P. (2018). Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells. Nature cell biology, Vol.20 (8), pp. 954-965.

Tacconi, E.M. Lai, X. Folio, C. Porru, M. Zonderland, G. Badie, S. Michl, J. Sechi, I. Rogier, M. Matía García, V. Batra, A.S. Rueda, O.M. Bouwman, P. Jonkers, J. Ryan, A. Reina‐San‐Martin, B. Hui, J. Tang, N. Bruna, A. Biroccio, A. Tarsounas, M. (2017). BRCA 1 and BRCA 2 tumor suppressors protect against endogenous acetaldehyde toxicity. Embo molecular medicine, Vol.9 (10), pp. 1398-1414.

Bruna, A. Rueda, O.M. Greenwood, W. Batra, A.S. Callari, M. Batra, R.N. Pogrebniak, K. Sandoval, J. Cassidy, J.W. Tufegdzic-Vidakovic, A. Sammut, S.-. Jones, L. Provenzano, E. Baird, R. Eirew, P. Hadfield, J. Eldridge, M. McLaren-Douglas, A. Barthorpe, A. Lightfoot, H. O’Connor, M.J. Gray, J. Cortes, J. Baselga, J. Marangoni, E. Welm, A.L. Aparicio, S. Serra, V. Garnett, M.J. Caldas, C. (2016). A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds. Cell, Vol.167 (1), pp. 260-274.e22.

Cassidy, J.W. Batra, A.S. Greenwood, W. Bruna, A. (2016). Patient-derived tumour xenografts for breast cancer drug discovery. Endocrine-related cancer, Vol.23 (12), pp. T259-T270.  show abstract

Bruna, A. Rueda, O.M. Caldas, C. (2016). Modeling Breast Cancer Intertumor and Intratumor Heterogeneity Using Xenografts. Cold spring harbor symposia on quantitative biology, Vol.81, pp. 227-230.

Cassidy, J.W. Caldas, C. Bruna, A. (2015). Maintaining Tumor Heterogeneity in Patient-Derived Tumor Xenografts. Cancer research, Vol.75 (15), pp. 2963-2968.

Eirew, P. Steif, A. Khattra, J. Ha, G. Yap, D. Farahani, H. Gelmon, K. Chia, S. Mar, C. Wan, A. Laks, E. Biele, J. Shumansky, K. Rosner, J. McPherson, A. Nielsen, C. Roth, A.J. Lefebvre, C. Bashashati, A. de Souza, C. Siu, C. Aniba, R. Brimhall, J. Oloumi, A. Osako, T. Bruna, A. Sandoval, J.L. Algara, T. Greenwood, W. Leung, K. Cheng, H. Xue, H. Wang, Y. Lin, D. Mungall, A.J. Moore, R. Zhao, Y. Lorette, J. Nguyen, L. Huntsman, D. Eaves, C.J. Hansen, C. Marra, M.A. Caldas, C. Shah, S.P. Aparicio, S. (2015). Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution. Nature, Vol.518 (7539), pp. 422-426.

Tufegdzic Vidakovic, A. Rueda, O.M. Vervoort, S.J. Sati Batra, A. Goldgraben, M.A. Uribe-Lewis, S. Greenwood, W. Coffer, P.J. Bruna, A. Caldas, C. (2015). Context-Specific Effects of TGF-β/SMAD3 in Cancer Are Modulated by the Epigenome. Cell reports, Vol.13 (11), pp. 2480-2490.

Bruna, A. Greenwood, W. Le Quesne, J. Teschendorff, A. Miranda-Saavedra, D. Rueda, O.M. Sandoval, J.L. Vidakovic, A.T. Saadi, A. Pharoah, P. Stingl, J. Caldas, C. (2012). TGFβ induces the formation of tumour-initiating cells in claudinlow breast cancer. Nature communications, Vol.3 (1).

Bruna, A. Darken, R.S. Rojo, F. Ocaña, A. Peñuelas, S. Arias, A. Paris, R. Tortosa, A. Mora, J. Baselga, J. Seoane, J. (2007). High TGFβ-Smad Activity Confers Poor Prognosis in Glioma Patients and Promotes Cell Proliferation Depending on the Methylation of the PDGF-B Gene. Cancer cell, Vol.11 (2), pp. 147-160.

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