Main Menu

Evolutionary Genomics and Modelling Team

Professor Andrea Sottoriva’s team uses biological, clinical and mathematical expertise, in order to decipher how cancer progresses, metastasises and develops treatment resistance.

Team leader

Professor Andrea Sottoriva

Professor Andrea Sottoriva

Professor Andrea Sottoriva uses genomics and computational approaches to understand cancer as a complex system. He obtained a degree in computer science and worked in particle physics before switching to biomedical research. He is the Deputy Director of the ICR's Centre for Evolution and Cancer.

ORCID 0000-0001-6709-9533

Team members

 Giulio  Caravagna
Giulio Caravagna
Postdoctoral Researcher

I am a Data Scientist with a background in Computer Science. I am now training in Cancer Evolution with Professor Sottoriva. Previously, I was at the University of Edinburgh (Lab of Machine Learning for Computational Biology and Bioinformatics), and at Milan-Bicoocca (Bioinformatics and Systems Biology). I hold a PhD in from the University of Pisa. At the ICR, I develop new methods to measure cancer evolutionary dynamics from genome sequencing data.

 Kate Chkhaidze

I am a PhD student studying cancer evolution using statistical and computational methods. My background is in pure mathematics (BSc) and statistics (MSc). I joined the lab in October 2015 to commence my studies.

 George Cresswell
George Cresswell
Postdoctoral Researcher ORCID 0000-0003-3303-068X

I am a post-doctoral bioinformatician researching cancer evolution using genomics with a particular interest in chromosomal instability. I obtained my degree in Biochemistry at the University of Manchester and then my PhD at the Francis Crick Institute researching paediatric cancer evolution. As part of Professor Sottoriva's team, I am involved in multiple projects focusing on the evolutionary patterns of several adult cancers including breast, colon and prostate.

 Inma Spiteri
Inma Spiteri
Lab manager ORCID 0000-0002-1097-8972

I am a Senior Scientific Officer specialising in cancer genomics. I joined Professor Sottoriva's lab in October 2014 and have been involved in multiple projects developing and applying novel genomics methodologies to study tumour evolution. I studied Pharmacy and Biochemistry in Madrid (Spain) and did my PhD at the University of Kingston (UK).

 Reda Stankunaite
Reda Stankunaite
PhD Student ORCID 0000-0003-3977-7020

I obtained an MSci in Biochemistry from the University of Glasgow in 2018. In October 2018 I joined the labs of Dr Michael Hubank and Professor Andrea Sottoriva to investigate the use of liquid biopsy to monitor clonal frequency and emergence of resistance mutations in paediatric cancers.

 Katharine Webb
Katharine Webb
Clinical PhD Student

I am an oncology doctor, taking time out of registrar training to do a PhD in Professor Sottoriva’s lab. I obtained my medical degree and a BSc (Psychiatry) at Imperial College, and an MSc at the ICR (Oncology). My project will be focusing on studying clonal evolution in prostate cancer.

 Bingjie Chen
Bingjie Chen
Postdoctoral Training Fellow
 Javier Fernandez Mateos
Javier Fernandez Mateos
Postdoctoral Researcher
 Timon Heide
Timon Heide
PhD Student
Chela James
Senior Bioinformatics Officer – Data Scientist
 Haider Tari
Haider Tari
PhD student
 Nick Trahearn
Nick Trahearn
Postdoctoral Researcher
 Erika Yara
Erika Yara
Higher Scientific Officer
Luis Zapata Ortiz
Postdoctoral Researcher