Professor Richard Houlston’s team works to identify cancer susceptibility genes and understand how these can cause cancer.
Professor Richard Houlston is Head of the Division of Genetics and Epidemiology. His research focuses on the identification and characterisation of genetic susceptibility to cancer.
I come from a PhD background in applied statistics, with knowledge of both frequentist and Bayesian statistics, and our group is using a variety of methods to understand how the incidence of colorectal cancer is affected by both genetic and environmental variables. In particular, I hope to improve my skills in bioinformatics and systems biology within the application of cancer.
Dr Andrea Gunnell is a cell biologist working on the identification of new predisposition alleles for myeloma through GWAS analysis and molecular genetic functional studies to elucidate biological basis for genetic susceptibility.
Dr Sureyya Kose recently earned her PhD in Chemistry, investigating the interaction between microbial gene expression and host innate immunity to reveal processes that may lead to cholelithiasis.
Presently, her work involves the identification of genetic susceptibility to childhood cancer.
I am currently investigating the molecular mechanism of drug resistance in multiple myeloma using molecular and cell biology techniques.
Dr James Smith is a molecular biologist working on the integration of 3D chromatin data and epigenetic landscapes to identify non-coding regions if the genome involved in both colon and renal cancer predisposition and tumour development.
Dr Amit Sud is an Academic Clinical Lecturer in Genetics and Epidemiology at the ICR and is completing his Haematology training at The Royal Marsden hospital.
Dr Jayaram Vijayakrishnan is a molecular geneticist investigating genetic predisposition to cancer. His work involves the use of molecular and cell biology techniques and subsequent bioinformatic analysis of data.
I'm in the first year of my postdoc after finishing my PhD in the Houlston Lab. I’m investigating inherited predisposition to multiple myeloma. My work involves the identification and characterisation of germline risk variants for myeloma with a view to improve our understanding of pathways relevant to the disease.