Dr Gideon Coster’s team investigates how cells produce accurate copies of their genome during cell division. Importantly, errors during genome replication can be both a cause, and a consequence, of cancer.
Dr Gideon Coster studies how errors during genome DNA replication are avoided or dealt with using a combination of in vitro biochemistry, genetics, proteomics and cell biology. He joined the ICR in October 2018 as a Sir Henry Dale Fellow.
Manuel obtained his PhD from the University of Birmingham in 2018. In January 2019 he joined Dr Gideon Coster's lab at the ICR to investigate mismatch repair and DNA replication.
Sophie completed her BSc in Genetics at the University of Leeds with an Industrial Placement Year at Freeline in London. She joined the Coster lab in October 2019 to carry out her PhD project investigating the effects of G-quadruplex structures on replication.