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Cancer Research UK Children’s Brain Tumour Centre of Excellence

A joint initiative led by The Institute of Cancer Research and the University of Cambridge, this centre brings together world experts in paediatric brain tumour research and drug discovery. We aim to transform the way new curative treatments for children with brain tumours are developed.

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At the ICR, we are applying our expertise in medicinal chemistry to develop new small molecule therapeutics and chemical tools to understand cancer biology.

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Centre staff members

Medicinal Chemistry 2 Team


Dr Lindsay EvansDr Lindsay Evans

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I am a medicinal chemist with a background in both anticancer and antimicrobial drug discovery. I joined the newly established CBTCE in November 2019 and have been working in collaboration with the University of Cambridge to initiate the Centre’s first research projects. The aim of the CBTCE is to transform the way we develop treatments for children with brain tumours. I am interested in developing new small molecule therapeutics and chemical probes to interrogate cancer biology.

 
 

Dr Robert GillespieDr Robert Gillespie

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I joined the ICR in 2020 as a Postdoctoral Training Fellow working in the Children’s Brain Tumour Centre of Excellence (CBTCE). My role within the team is to design and synthesize novel compounds with activity against brain tumours and to design tool compounds for use in target identification experiments. 

 
 

Dr Jack O'HanlonDr Jack O'Hanlon

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I am a medicinal chemist working within the Children's Brain Tumour Centre of Excellence on the synthesis of new compounds for the treatment of paediatric ependymomas. 

 
 

Dr Rosemary HuckvaleDr Rosemary Huckvale

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I am a medicinal chemist and have worked on a number of different drug discovery projects. I design and synthesise drug-like molecules as potential new targeted therapeutics, and I have also worked with small molecule chemical probes to look at how proteins function in cancer cells. I am interested in designing and making compounds with new chemical modalities to hit tumour cells where they are vulnerable.