Photo-dynamic versus white light-guided treatment of non-muscle invasive bladder cancer: randomised phase III trial of clinical and cost-effectiveness
Disease site: Bladder cancer
Treatment modality: Surgery
Status: In follow-up
PHOTO is a pragmatic, multicentre, randomised controlled phase III trial, investigating the efficacy of using photo-dynamic diagnosis (PDD) under blue light – instead of white light – for transurethral resection of bladder tumour (TURBT) in intermediate and high risk non-muscle invasive bladder cancer.
533 patients will be recruited from UK sites. Half of the participants will undergo surgery using PDD under blue light. The other participants will undergo surgery using standard white light. All participants will be followed up regularly during the three year trial period.
The PHOTO trial is managed by ICR and CHaRT.
Chief Investigator: Mr Rakesh Heer, The Newcastle upon Tyne Hospitals NHS Foundation Trust
ICR-CTSU Scientific Lead: Prof Emma Hall
Trial management contacts: [email protected] and [email protected]
Sponsor: The Newcastle upon Tyne Hospitals NHS Foundation Trust
Funding: National Institute for Health Research
View PHOTO on the UK Clinical Trials Gateway.
Read a plain English summary of PHOTO from Cancer Research UK.
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